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Base Excess

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161. Challenges of Integrating an Evidence-based Intervention in Health Departments to Prevent Excessive Gestational Weight Gain among Low-income Women Full Text available with Trip Pro

Challenges of Integrating an Evidence-based Intervention in Health Departments to Prevent Excessive Gestational Weight Gain among Low-income Women To examine health departments' (HD) capacity to adapt and implement an intervention to prevent excessive gestational weight gain.Seventy-seven stakeholders (nurses, nutritionists, social workers, health educators, health directors, and multilingual service providers) in nine HDs participated. A descriptive mixed methods approach was used to collect (...) data at workshops held onsite to introduce the evidence-based intervention (EBI) and discuss its adaptation.A survey was administered to assess the intervention's fit with the HDs context. Generalized logit mixed models were used to analyze the survey data. The discussions of adaptation were audiotaped and thematically analyzed to identify factors influencing implementation.The majority of stakeholders desired to participate in the training portion of the EBI, but they were reluctant to adopt

2016 Public health nursing (Boston, Mass.)

162. A School-Based Intervention to Reduce Excess Weight in Overweight and Obese Primary School Students. (Abstract)

A School-Based Intervention to Reduce Excess Weight in Overweight and Obese Primary School Students. This study evaluated the effect of an intervention for reducing excess weight gain in primary school-age children in Tehran.A cluster-randomized controlled trial was conducted in 12 primary schools in Tehran. Three hundred thirty-four pupils, 167 in the intervention and 167 in the comparison group, determined to be overweight or obese based on World Health Organization standards, were recruited

2016 Biological research for nursing Controlled trial quality: uncertain

163. A Comparison between Two Dilute Citrate Solutions (15 vs. 18 mmol/l) in Continuous Renal Replacement Therapy: The Base Excess and Renal Substitution Solution Study. (Abstract)

A Comparison between Two Dilute Citrate Solutions (15 vs. 18 mmol/l) in Continuous Renal Replacement Therapy: The Base Excess and Renal Substitution Solution Study. The study aimed to compare the changes in biochemistry occurring in patients undergoing continuous renal replacement therapy (CRRT) using 2 trisodium citrate solutions, Baxter hemofiltration fluid containing 18 mmol/l (C18) and Baxter NamSol, a custom manufactured solution containing 15 mmol/l (C15), both delivered as regional (...) base excess and serum bicarbonate concentration, all being higher in the C18 group (p < 0.01). By day 5, the PaCO2 had also risen in the C18 group (p = 0.03).The C15 solution provided equivalent filter life to the C18 solution but without significant hypernatremia and metabolic alkalosis.© 2016 S. Karger AG, Basel.

2016 Blood purification Controlled trial quality: uncertain

164. Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study. Full Text available with Trip Pro

Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study. This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20-40 years in a nationwide population database in Taiwan.Subjects were selected from Taiwan's National Health Insurance Research Database for the period 2001-2008 and were followed up until the end of 2010. A total of 4,523 subjects were admitted for the first time with primary diagnosis of hip

2016 BMC Musculoskeletal Disorders

165. Will the Need-Based Planning of Health Human Resources Currently Undertaken in Several Countries Lead to Excess Supply and Inefficiency? A Comment on Basu and Pak. (Abstract)

Will the Need-Based Planning of Health Human Resources Currently Undertaken in Several Countries Lead to Excess Supply and Inefficiency? A Comment on Basu and Pak. Basu and Pak (2014) argue that need-based workforce planning models would not maximize social welfare, and use of need-based models would result in inefficiency. They propose that planning be based on service utilization to incorporate preferences or other socioeconomic factors. We show that the analysis is based on inappropriate (...) considerations of the nature of healthcare demand, a misrepresentation of need-based approaches and misunderstanding publicly funded healthcare system objectives. We explain how current levels of utilization emerge from workload and income interests of providers that underlie utilization-based models and are incompatible with public goals of maximizing health gains. Copyright © 2016 John Wiley & Sons, Ltd.Copyright © 2016 John Wiley & Sons, Ltd.

2016 Health economics

166. Measuring baseline level of excessive alcohol intake in pregnancy in the West of Scotland

in Pregnancy. Alcohol Research & Health. 28:38-43. 6 7 APPENDIX Box 1: Deriving a “Best Guess” estimate of the prevalence of heavy drinking in the most deprived regions of Glasgow, using two approaches: (1) Based on smoking figures alone: in the three most deprived regions of Glasgow smoking during pregnancy is approximately 60-80% higher than the Scottish average (source: GCPH profiles). If we assume that heavy drinking during pregnancy has a similar excess then we might expect the prevalence of heavy (...) (based on the sex patterning in alcohol related GP consultations [ongoing work, DeS]), giving an estimated excess of alcohol related deaths in these neighbourhoods of around 60-80% compared to the Scottish estimates. The excess of heavy drinking during pregnancy is likely to be lower still, based on that seen with smoking figures (2a, above). Reflecting this, the estimated excess in heavy drinking of 60-80% can be reduced by a further 5-20% giving an estimated excess of heavy drinking during

2012 Glasgow Centre for Population Health

167. Predictors for Development of Excessive Daytime Sleepiness in Women: A Population-Based 10-Year Follow-Up Full Text available with Trip Pro

Predictors for Development of Excessive Daytime Sleepiness in Women: A Population-Based 10-Year Follow-Up To analyze predictors of excessive daytime sleepiness (EDS) and to analyze how changes within risk factors over time predict incident EDS in women.Population-based prospective study.General population of the City of Uppsala, Sweden.From a random, general population sample of 7,051 women from the Sleep and HEalth in women ("SHE") cohort, 4,322 women without EDS at baseline were followed up (...) for predicting incident excessive daytime sleepiness (EDS) and, in addition, somatic disease, obesity, and snoring predicted EDS. It is important not only to treat these conditions but also to inform women of the importance of a healthy lifestyle in order to prevent and reduce EDS in women.© 2015 Associated Professional Sleep Societies, LLC.

2015 Sleep

168. Adoption and maintenance of gym-based strength training in the community setting in adults with excess weight or type 2 diabetes: a randomized controlled trial. Full Text available with Trip Pro

Adoption and maintenance of gym-based strength training in the community setting in adults with excess weight or type 2 diabetes: a randomized controlled trial. Participant adoption and maintenance is a major challenge in strength training (ST) programs in the community-setting. In adults who were overweight or with type 2 diabetes (T2DM), the aim of this study was to compare the effectiveness of a standard ST program (SST) to an enhanced program (EST) on the adoption and maintenance of ST (...) 1.5-45.5). No significant between-group differences were observed for maintenance of ST in either pooled or stratified analyses. In those with T2DM, there was a significant reduction in HbA1c in the EST compared to SST group during the adoption phase (net difference, -0.13 % [-0.26 to -0.01]), which persisted after 12-months (-0.17 % [-0.3 to -0.05]).A behaviorally-focused community-based EST intervention was more effective than a SST program for the adoption of ST in adults with excess weight

2015 The international journal of behavioral nutrition and physical activity Controlled trial quality: uncertain

169. Internet-based Exposure Therapy for Excessive Worry

Internet-based Exposure Therapy for Excessive Worry Internet-based Exposure Therapy for Excessive Worry - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Internet-based Exposure Therapy for Excessive Worry (...) to Brief Summary: The purpose of this study is to examine if an internet-based exposure therapy is effective in reducing excessive worry amongst patients who suffer from this problem. Condition or disease Intervention/treatment Phase Excessive Worry Rumination Behavioral: Internet-based cognitive-behavior therapy Not Applicable Detailed Description: Trial Objectives: Primary objective is to investigate whether an Internet-based exposure therapy can effectively reduce the degree of excessive worry

2015 Clinical Trials

170. Long Term Excess Mortality of Acute Myocardial Infarction in Patients With and Without Diabetes: A Population-based Cohort Study

Long Term Excess Mortality of Acute Myocardial Infarction in Patients With and Without Diabetes: A Population-based Cohort Study Long Term Excess Mortality of Acute Myocardial Infarction in Patients With and Without Diabetes: A Population-based Cohort Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have (...) reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Long Term Excess Mortality of Acute Myocardial Infarction in Patients With and Without Diabetes: A Population-based Cohort Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02591576 Recruitment

2015 Clinical Trials

171. Excess mortality in severe mental illness: 10-year population-based cohort study in rural Ethiopia. Full Text available with Trip Pro

Excess mortality in severe mental illness: 10-year population-based cohort study in rural Ethiopia. Evidence on mortality in severe mental illness (SMI) comes primarily from clinical samples in high-income countries.To describe mortality in people with SMI among a population cohort from a low-income country.We followed-up 919 adults (from 68 378 screened) with SMI over 10 years. Standardised mortality ratios (SMR) and years of life lost (YLL) as a result of premature mortality were

2015 British Journal of Psychiatry

172. Excessive daytime sleepiness and falls among older men and women: cross-sectional examination of a population-based sample Full Text available with Trip Pro

Excessive daytime sleepiness and falls among older men and women: cross-sectional examination of a population-based sample Excessive daytime sleepiness (EDS) has been associated with an increased risk for falls among clinical samples of older adults. However, there is little detailed information among population-representative samples. The current study aimed to assess the relationship between EDS and falls among a cohort of population-based older adults.This study assessed 367 women aged 60-93

2015 BMC geriatrics

173. Excess cause-specific mortality in in-patient-treated individuals with personality disorder: 25-year nationwide population-based study. Full Text available with Trip Pro

Excess cause-specific mortality in in-patient-treated individuals with personality disorder: 25-year nationwide population-based study. Although personality disorders are associated with increased overall mortality, less is known about cause of death and personality type.To determine causes of mortality in ICD personality disorders.Based on data from Swedish nationwide registers, individuals admitted to hospital with a primary diagnosis of personality disorder between 1987 and 2011 were

2015 British Journal of Psychiatry

174. Feasibility and Initial Efficacy Evaluation of a Community-Based Cognitive-Behavioral Lifestyle Intervention to Prevent Excessive Weight Gain During Pregnancy in Latina Women Full Text available with Trip Pro

Feasibility and Initial Efficacy Evaluation of a Community-Based Cognitive-Behavioral Lifestyle Intervention to Prevent Excessive Weight Gain During Pregnancy in Latina Women About 48 % of US women gain more weight during pregnancy than recommended by the Institute of Medicine (IOM). Excessive gestational weight gain is a major risk factor for obesity in both women and offspring over their lifetimes, and should be avoided. This study was designed to test the feasibility and initial efficacy (...) of a prenatal behavioral intervention in a sample of low-income, predominantly Latina women. The intervention was delivered in groups of 8-10 women in a community recreation center, and structured to reduce the proportion of women who gained weight in excess of IOM guidelines. Recruitment targets were met in 3 months: 135 pregnant women (>10 and <28 weeks) were randomly assigned to receive a 12-week intervention (n = 68) or usual care (n = 67). Retention rate was 81 %. On average, women attended 4 of 12

2015 Maternal and child health journal Controlled trial quality: uncertain

175. Comparing biomarkers of traumatic shock: the utility of anion gap, base excess, and serum lactate in the ED. (Abstract)

Comparing biomarkers of traumatic shock: the utility of anion gap, base excess, and serum lactate in the ED. Biomarkers such as serum lactate, anion gap (AG), and base excess (BE) have been shown to be of use in determining shock in patients with seemingly normal vital signs. We seek to determine if these biomarkers can be used interchangeably in patients with trauma in the emergency setting based on their test characteristics and correlation to each other.A prospective observational cohort

2015 American Journal of Emergency Medicine

176. Outpatient biopsy for diagnosis of suspicious lesions of the larynx pharynx and tongue base

Outpatient biopsy for diagnosis of suspicious lesions of the larynx pharynx and tongue base SHTG Advice Statement | 1 Advice Statement 012-18 October 2018 Advice Statement Outpatient biopsy, for diagnosis of suspicious lesions of the larynx, pharynx and tongue base Advice for NHSScotland Outpatient biopsy has a low rate of complications and, in most cases, sufficient tissue for pathological examination can be obtained. Where there strong clinical suspicion of malignancy, outpatient biopsy (...) and neck outpatient clinics commonly undergo transnasal endoscopy to visualise the larynx, pharynx and tongue base. When suspected malignant lesions are identified, the ‘gold standard’ investigation is direct laryngoscopy under general anaesthetic in the operating theatre. In addition to anaesthetic risk, this carries risk of dental damage, and in some cases, requirement for SHTG Advice Statement | 2 tracheostomy. The need to schedule theatre time, an overnight or day-case hospital bed and pre

2019 Evidence Notes from Healthcare Improvement Scotland

177. Systematic evidence-based review: outcomes from exome and genome sequencing for pediatric patients with congenital anomalies or intellectual disability

Systematic evidence-based review: outcomes from exome and genome sequencing for pediatric patients with congenital anomalies or intellectual disability Systematic evidence-based review: outcomes from exome and genome sequencing for pediatric patients with congenital anomalies or intellectual disability A full list of authors and affiliations appears at the end of the paper. Disclaimer: The ACMG has recruited expert panels, chosen for their scientific and clinical expertise, to conduct (...) ,andtoconsiderothermedicalandscientificinformationthatbecomesavailableafter that date. Purpose: Exome and genome sequencing (ES/GS) are performed frequently in patients with congenital anomalies, developmental delay, or intellectual disability (CA/DD/ID), but the impact of resultsfromES/GSonclinicalmanagementandpatientoutcomesis not well characterized. A systematic evidence review (SER) can support future evidence-based guideline development for use of ES/ GS in this patient population. Methods: We undertook an SER to identify primary literature from January 2007

2020 American College of Medical Genetics and Genomics

178. Knowledge-based clinical decision support systems

Knowledge-based clinical decision support systems SHTG Assessment | 1 SHTG Assessment Number 02 April 2020 Knowledge-based clinical decision support systems What were we asked to look at? The Scottish Government asked us to review the evidence on the impact of knowledge- based clinical decision support systems on service delivery, patient, and clinical outcomes. They also asked that we review the evidence on barriers and enablers for successful implementation of these systems in clinical (...) practice. Why is this important? Healthcare professionals are required to make decisions relating to patient care on a daily basis. With the increasing volume of evidence available, and improvements in technology, there is an opportunity to introduce tools to aid healthcare professionals in making decisions relating to patient care. Clinical decision support systems (CDSS) are one such tool, generating evidence-based, patient-specific advice at the point-of-care. What was our approach? We produced

2020 SHTG Advice Statements

179. Prior psychiatric hospitalization is associated with excess mortality in patients hospitalized with non-cardiac chest pain: a data linkage study based on the full Scottish population (1991-2006) Full Text available with Trip Pro

Prior psychiatric hospitalization is associated with excess mortality in patients hospitalized with non-cardiac chest pain: a data linkage study based on the full Scottish population (1991-2006) Non-cardiac chest pain (NCCP) is considered a benign condition. We investigate case-fatality following an incident hospitalization for NCCP and determine whether previous psychiatric hospitalization is associated with short-term mortality.This was a population-based retrospective cohort study of 159 888

2012 EvidenceUpdates

180. Overview of acid-base and electrolyte disorders

Overview of acid-base and electrolyte disorders Overview of acid-base and electrolyte disorders - Summary of relevant conditions | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Overview of acid-base and electrolyte disorders Last reviewed: February 2019 Last updated: November 2018 Introduction Disorders of blood chemistry may be caused by dietary factors, underlying medical conditions, and medical treatments. Resulting imbalances include acidosis (pH (...) (a mineralocorticoid hormone), and parathyroid hormone (PTH). Acid-base balance is linked to fluid and electrolyte balance, and is normally controlled and maintained by immediate buffer systems via the kidneys and the pulmonary system. Berend K, de Vries AP, Gans RO. Physiological approach to assessment of acid-base disturbances. N Engl J Med. 2014 Oct 9;371(15):1434-45. http://www.ncbi.nlm.nih.gov/pubmed/25295502?tool=bestpractice.com Respiratory acidosis and alkalosis are accompanied by compensatory renal

2018 BMJ Best Practice

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