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41. Cerebral palsy: Scenario: Adult with confirmed cerebral palsy

or joint disorder is suspected and causing pain or affecting posture or function. These may include osteoarthritis, cervical instability or spondylosis (including athetosis), spinal deformity (including scoliosis, kyphosis and lordosis), subluxation of the hips, wrist and shoulders, biomechanical knee problems, and abnormalities of the foot structure. Be aware that low bone mineral density is common in adults with CP, particularly in people with reduced mobility or reduced weight bearing, taking

2016 NICE Clinical Knowledge Summaries

42. Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in the Era of Doppler Echocardiography Full Text available with Trip Pro

, and the movements should be differentiated from tics, athetosis, conversion reaction, and hyperkinesis. Evidence of a recent group A streptococcal infection may be difficult or impossible to document because of the long latent period between the inciting streptococcal infection and the onset of chorea. Worsening of choreiform movements in a child with previous low-grade residual chorea may be hard to distinguish from a new attack of chorea. Skin Findings Erythema marginatum is the unique, evanescent, pink rash

2015 American Heart Association


. In most studies, the instruments of assessment encompassed the domains of functions, body structure, and activity. The percentage of posterior root sections was close to 50%. Primary indications for SDR included ambulatory spastic diplegia, presence of spasticity that interfered with mobility, good strength of lower limbs and trunk muscles, no musculoskeletal deformities, dystonia, ataxia or athetosis, and good cognitive function. Postoperative physical therapy is part of SDR treatment protocols

2018 Revista Paulista de Pediatria

44. Genetic landscape of pediatric movement disorders and management implications Full Text available with Trip Pro

, targeted next-generation sequencing, or whole exome sequencing.There were 51 patients in the Pediatric Genetic Movement Disorder Clinic. Twenty-five patients had dystonia, 27 patients had ataxia, 7 patients had chorea-athetosis, 8 patients had tremor, and 7 patients had hyperkinetic movements. A genetic diagnosis was confirmed in 26 patients, including in 20 patients with ataxia and 6 patients with dystonia. Targeted next-generation sequencing panels confirmed a genetic diagnosis in 9 patients

2018 Neurology: Genetics

45. Functions and dysfunctions of the basal ganglia in humans Full Text available with Trip Pro

Functions and dysfunctions of the basal ganglia in humans Involuntary movements and parkinsonism have been interesting and important topics in neurology since the last century. The development of anatomical and physiological studies of the neural circuitry of motor systems has encouraged the study of movement disorders by means of pathophysiology and brain imaging.Multichannel electromyography from affected muscles has generated objective and analytical data on chorea, ballism, athetosis

2018 Proceedings of the Japan Academy. Series B, Physical and biological sciences

46. DBS in the Treatment of Intractable Movement Disorders

Essential Tremors, Dystonia, Chorea, Dyskinesia, and Athetosis. Hypokinetic movement disorders refer to akinesia (lack of movement), hypokinesia (reduced amplitude of movements), bradykinesia (slow movement) and rigidity. In primary movement disorders, the abnormal movement is the primary manifestation of the disorder. In secondary movement disorders, the abnormal movement is a manifestation of another systemic or neurological disorder. The basal ganglia include the striatum (caudate. putamen, nucleus

2018 Clinical Trials

47. Comparing Virtual Reality Therapy With Modified-CIMT Versus Modified-CIMT Alone in Hemiparetic Children

more than 3 at shoulder/elbow /wrist Contractures of the affected limb Severe movement disorder like dystonia, choreo-athetosis or ballismus interfering with purposeful limb movement Any congenital brain malformation detected on conventional MRI brain Recent orthopedic surgery/cast/splint in the affected limb Botulinum toxin/phenol blocking in the affected limb in the past 6 months or are planning to receive in the study period Those receiving tone modifying agents in week before enrollment

2017 Clinical Trials

48. Audiological findings in children with ataxia-telangiectasia (A-T) syndrome. (Abstract)

Audiological findings in children with ataxia-telangiectasia (A-T) syndrome. To assess peripheral and central hearing in children with A-T.3 children diagnosed with A-T according to the diagnostic criteria for A-T of the European Society for Immunodeficiencies. Involuntary movements were seen in the form of chorea-athetosis together with tremors. They were examined to assess both peripheral and central hearing was assessed (hearing thresholds). Sound-field testing, tympanometry, acoustic

2017 International Journal of Pediatric Otorhinolaryngology

49. The Movement Disorder of Brain-Lung-Thyroid Syndrome Can be Responsive to Methylphenidate Full Text available with Trip Pro

, And Neonatal Respiratory Distress IM Athetosis drug therapy genetics physiopathology Central Nervous System Stimulants therapeutic use Child Chorea drug therapy genetics physiopathology Congenital Hypothyroidism drug therapy genetics physiopathology Female Humans Methylphenidate therapeutic use Respiratory Distress Syndrome, Newborn drug therapy genetics physiopathology Thyroid Nuclear Factor 1 genetics Chorea NKX2-1-related disorder brain-lung-thyroid syndrome methylphenidate psychostimulant Funding

2017 Tremor and Other Hyperkinetic Movements

50. Huntington's Chorea

dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including

2018 FP Notebook

51. Kernicterus

of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child (...) Neurology, 5th ed, p613) Definition (CSP) brain disorder associated with high levels of bilrubin; clinical features include athetosis, muscle spasticity or hypotonia, impaired vertical gaze, and deafness; nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the blood-brain barrier; this condition occurs primarily in neonates with perinatal blood incompatibilities, but may rarely occur in adults. Concepts Disease or Syndrome ( T047 ) MSH

2018 FP Notebook

52. Dentatorubral-Pallidoluysian Atrophy (DRPLA)

; choreoathetosis (involuntary movements consisting of brief and irregular contractions [chorea] and writhing motions [athetosis]); psychiatric disturbances (including personality changes, hallucinations, and delusions); and dementia. However, these correlations are not absolute and there is phenotypic overlap between the juvenile and adult forms of the condition. In addition, DRPLA patients may experience additional neurological symptoms, such as tremor, dystonia (sustained muscle contractions), and dysarthria

2011 Health Technology Assessment (HTA) Database.

53. Rater reliability and scoring duration of the Quality Function Measure in ambulant children with hyperkinetic movement disorders. Full Text available with Trip Pro

Rater reliability and scoring duration of the Quality Function Measure in ambulant children with hyperkinetic movement disorders. To examine intra- and interrater reliability/agreement, and time taken to score, when the Quality Function Measure (QFM) is applied to children with hyperkinetic movement disorders (HMD; e.g. dystonia, chorea, athetosis, tremor, and myoclonus).Fifteen ambulant children with HMD participated (eight males, seven females; mean age 13y 7mo, SD 3y 7mo). Three trained

2016 Developmental Medicine and Child Neurology

54. A Pilot Study of the Effect of Botulinum Toxin Type a (Dysport®, Abobotulinum Toxin A) Injection on Changes in Musculotendinous Length and Dynamics of Hamstring Muscles During Gait in Children With Spastic Cerebral Palsy Walking With Excessive Knee Flexi

previous BoNT-A injections Children who have a mixed type of CP (Athetosis, dystonia) or other movement disorder (eg. ataxia) Children who are participating in other investigational study at the moment Children who are not suitable for this study according to the investigator's discretion Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided

2016 Clinical Trials

55. The hyperkinetic movement disorder of FOXG1-related epileptic-dyskinetic encephalopathy. Full Text available with Trip Pro

with different mutations or copy number variations affecting the FOXG1 gene and describe the peculiar pattern of the associated movement disorder.The age of the patients in the study ranged from 2 to 17 years old (six females, two males). They had severe epilepsy and exhibited a complex motor disorder including various combinations of dyskinetic and hyperkinetic movements featuring dystonia, chorea, and athetosis. The onset of the movement disorder was apparent within the first year of life, reached its

2015 Developmental Medicine and Child Neurology

56. Dystonia and Paroxysmal Dyskinesias: Under-Recognized Movement Disorders in Domestic Animals? A Comparison with Human Dystonia/Paroxysmal Dyskinesias Full Text available with Trip Pro

Dystonia and Paroxysmal Dyskinesias: Under-Recognized Movement Disorders in Domestic Animals? A Comparison with Human Dystonia/Paroxysmal Dyskinesias Dystonia is defined as a neurological syndrome characterized by involuntary sustained or intermittent muscle contractions causing twisting, often repetitive movements, and postures. Paroxysmal dyskinesias are episodic movement disorders encompassing dystonia, chorea, athetosis, and ballism in conscious individuals. Several decades of research have

2015 Frontiers in veterinary science

57. Outcomes of cochlear implanted children with cerebral palsy: A holistic approach. (Abstract)

audiological, language, and communication assessments complemented by the assessment of functional abilities and the level of independence as evaluated by the Pediatric Evaluation of Disability Inventory (PEDI) and Gross Motor Function Classification System (GMFCS).The outcomes varied, as two children achieved hearing comprehension in open-set evaluations. These children presented the same type of CP, athetosis, but with different functional skills and GMFCS levels. Only one of the subjects had any spoken

2015 International Journal of Pediatric Otorhinolaryngology

58. Evaluating cerebellar dentatotomy for the treatment of spasticity with or without dystonia. (Abstract)

University (Smetwick, UK) in the 1980s. The following clinical aspects were analyzed: severity of spasticity, occurrence of abnormal movements (dystonia/athetosis), language fluency, gait, and overall clinical condition. Follow-up ranged from 0.5 to 94 (mean: 31.6) months. Immediate improvement was noted in 10 patients, and five of them had sustained this improvement at the time of the last assessment. A more pronounced improvement was observed for gait, relative to speech and abnormal movements

2015 British Journal of Neurosurgery

59. Do lycra garments improve function and movement in children with cerebral palsy?

case series and there was one case study. Relevant Paper(s) Author, date and country Patient group Study type (level of evidence) Outcomes Key results Study Weaknesses Blair et al, 24 Patients (15 months to 14 years) with cerebral palsy (7 spasticity, 5 athetosis, 7 dystonia, 4 ataxia, 1 hypotonia) and 8 controls (matched by age and ability). 8 patients given Lycra suits, for 8 h/day (4 weeks' wear, 3 weeks without, 6 weeks' wear) Descriptive study, crossover trial and recipient-control study (...) ). Children who continued to wear garments showed benefits on standardised tests and questionnaire Unable to carry out statistical analysis owing to small sample size. Lack of control group. Potential assessor bias as author was main assessor in every case except one. Lack of patient appropriate upper limb assessment tool Rennie et al, 8 Patients (5–11 years) (7 with cerebral palsy, 1 with Duchenne's muscular dystrophy). Predominant impairment: 5 spasticity, 1 athetosis, 1 hypotonia, 1 weakness. Wearing

2010 BestBETS

60. Motor Severity in Children With Cerebral Palsy Studied in a High-Resource and Low-Resource Country. Full Text available with Trip Pro

significantly with more spasticity and less dyskinetic types in the Australian sample (spasticity, P < .01; dystonia, P < .01; athetosis, P < .01). Birth risk factors were more common in the Bangladesh sample, with risk factors of low Apgar scores (Australia, P < .01), lethargy/seizures (Australia, P = .01), and term birth (Bangladesh, P = .03) associated with poorer gross motor function. Cognitive impairments were significantly more common in the Bangladesh children (P < .01), and visual impairments more

2014 Pediatrics

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