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Argyria

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1. Localized argyria: Troublesome side effect of acupuncture. (PubMed)

Localized argyria: Troublesome side effect of acupuncture. 28833654 2018 02 21 1468-3083 32 2 2018 Feb Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Localized argyria: troublesome side-effect of acupuncture. e62-e65 10.1111/jdv.14526 Park M Y MY Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea. Lee J S JS Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH

2017 Journal of the European Academy of Dermatology and Venereology

2. Occupational Argyria of the Nasal Mucosa (PubMed)

Occupational Argyria of the Nasal Mucosa A biopsy specimen from the nasal mucosa of a 37-year-old man disclosed a subepithelial accumulation of black granules mainly running parallel to the surface in the absence of any inflammatory infiltrate. Since the mucosal pigment was negative with Perls' stain and resisted to melanin bleach, an exogenous pigmentation was suspected. The biopsy specimen had been taken because of a diffuse steel-blue pigmentation of the nasal mucosa, incidentally discovered (...) during routine clinical examination. A diagnosis of occupational argyria of the nasal mucosa was finally made since the patient was a silver cleaner. Argyria is a rare cause of nasopharyngeal mucosal pigmentation; it is not a precancerous condition, but it can be mistaken for a melanosis or a melanocytic tumor both clinically and histopathologically. Clinicopathological correlation is mandatory, since the final diagnosis is based on a history of chronic silver exposure.

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2017 Head and neck pathology

3. A case of generalized argyria presenting with muscle weakness (PubMed)

A case of generalized argyria presenting with muscle weakness Argyria is a rare irreversible cutaneous pigmentation disorder caused by prolonged exposure to silver. Herein, we report a case of generalized argyria that developed after chronic ingestion of soluble silver-nano particles and presented with muscle weakness.A 74-year-old woman visited our emergency room, complaining of fever and mental deterioration. She was diagnosed with acute pyelonephritis and recovered after antibiotic therapy (...) . At presentation, diffuse slate gray-bluish pigmented patches were noticed on her face and nails. Two months prior to visiting our hospital, she was diagnosed with inflammatory myopathy and given steroid therapy at another hospital. We performed a nerve conduction study that revealed polyneuropathy. In skin biopsies from pigmented areas of the forehead and nose, the histopathologic results showed brown-black granules in basement membranes of sweat gland epithelia, which are diagnostic findings of argyria. We

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2017 Annals of occupational and environmental medicine

4. In vivo reflectance confocal microscopy characterization of silver deposits in localized cutaneous argyria. (PubMed)

In vivo reflectance confocal microscopy characterization of silver deposits in localized cutaneous argyria. Localized cutaneous argyria is a rare condition secondary to skin deposition of silver following exposure to substances containing this metal. The clinical appearance and dermoscopy findings require deep melanocytic lesions and particularly melanoma metastasis to be ruled out. Silver deposits are usually confirmed by scanning electron microscopy and/or energy-dispersive X-ray spectroscopy (...) . Herein we describe the in vivo reflectance confocal microscopy (RCM) features observed in one case of localized cutaneous argyria. These features include the presence of a hyperrefractile network in the papillary dermis and a periadnexal dotted bright pattern. In vivo RCM might be a useful tool for an early diagnosis of this uncommon entity.© 2016 British Association of Dermatologists.

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2016 British Journal of Dermatology

5. Pauci Immune crescentic glomerulonephritis in a patient with T-cell lymphoma and argyria. (PubMed)

Pauci Immune crescentic glomerulonephritis in a patient with T-cell lymphoma and argyria. Silver is a transition metal, toxic when ingested in significant amounts, causing argyria (skin deposition) and argyrosis (eye deposition). It is excreted mainly via the gastrointestinal tract with only small amounts eliminated by the kidneys, and rarely have cases of nephrotoxicity due to silver been reported. Here we present the case of a woman who used colloidal silver as an alternative remedy for a T (...) cell lymphoma, who subsequently developed argyria and a pauci-immune crescentic glomerulonephritis with evidence of extensive glomerular basement membrane silver deposition.A 47 year old woman of Indo-Asian descent with a T-cell lymphoma who refused conventional chemotherapy for 18 months but self-medicated with a remedy containing colloidal silver, was admitted with acute dialysis-dependent kidney injury. A kidney biopsy demonstrated a pauci-immune crescentic glomerulonephritis with deposition

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2016 BMC Nephrology

6. Argyria

Argyria Argyria Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Argyria Argyria Aka: Argyria , Silver Poisoning From Related Chapters (...) II. Pathophysiology Excessive oral silver intake Results in silver salt deposition in skin III. Symptoms Asymptomatic IV. Signs Permanent blue to bronze discoloration of skin, mucosa Darker coloration where skin exposed to light Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Argyria." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Argyria

2018 FP Notebook

7. 1064 nm Q-switched Nd:YAG laser for the treatment of Argyria: a systematic review.

1064 nm Q-switched Nd:YAG laser for the treatment of Argyria: a systematic review. Argyria is a benign skin disease characterized by blue to slate-grey discoloration that is caused by deposition of silver granules in the skin and/or mucus membranes as a result of long-term ingestion of ionized silver solutions or exposure to airborne silver particles. The skin discoloration can be generalized or localized and is exacerbated by sunlight. The skin discoloration is usually permanent, and until (...) recently, there has been no effective treatment for argyria. Over the past 6 years, a number of case reports and one case series have described cases of argyria that were successfully treated with a 1064 nm Q-switched (QS) neodymium-doped yttrium aluminium garnet (Nd:YAG) laser; however, a review of these studies has never been reported in the dermatologic literature. To review the use of the 1064 nm QS Nd:YAG laser for the treatment of argyria. A search of the National Library of Medicine's PubMed

2015 Journal of the European Academy of Dermatology and Venereology : JEADV

8. Dystrophic calcification and accentuated localized argyria after fractionated carbon dioxide laser therapy of hypertrophic scars. (PubMed)

Dystrophic calcification and accentuated localized argyria after fractionated carbon dioxide laser therapy of hypertrophic scars. Fractionated, ultrapulsed carbon dioxide (CO2) laser therapy is a powerful tool for the treatment of scars. Common adverse effects of this therapeutic modality have been previously documented. We describe 2 unreported adverse effects of ultrapulsed CO2 laser treatment of mature scars in a patient previously treated with silver-impregnated dressings.A teenage survivor (...) of toxic epidermal necrolysis presented with faint but diffuse dyschromia clinically and histologically consistent with localized argyria secondary to silver-impregnated dressings used years earlier. The patient was subsequently treated with fractionated CO2 for her scarring, but her hyperpigmentation worsened with each treatment. A subsequent biopsy specimen revealed a zone of dystrophic calcification with adjacent pseudo-ochronotic fibers that were not appreciated on biopsy specimens taken before CO2

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2014 JAMA dermatology (Chicago, Ill.)

9. Argyria (Follow-up)

Argyria (Follow-up) Argyria Treatment & Management: Medical Care, Surgical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTEyMS10cmVhdG1lbnQ= processing > Argyria Treatment & Management Updated: Sep 12 (...) , 2017 Author: Kamila K Padlewska, MD, PhD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Argyria Treatment Medical Care Treatment with depigmenting preparations is not satisfactory; however, according to some reports, 5% hydroquinone treatment may reduce the number of silver granules in the upper dermis and around sweat glands and diminish the number of melanocytes. Chelation attempts to remove silver from the body have been unsuccessful. Sunscreens and opaque

2014 eMedicine.com

10. Argyria (Overview)

Argyria (Overview) Argyria: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTEyMS1vdmVydmlldw== processing > Argyria Updated: Sep 12, 2017 Author: Kamila K Padlewska, MD (...) , PhD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Argyria Overview Background Argyria results from prolonged contact with or ingestion of silver salts. Argyria is characterized by gray to gray-black staining of the skin and mucous membranes produced by silver deposition. Silver may be deposited in the skin either from industrial exposure or as a result of medications containing silver salts. See the image below. A 92-year-old asymptomatic white man

2014 eMedicine.com

11. Argyria (Diagnosis)

Argyria (Diagnosis) Argyria: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTEyMS1vdmVydmlldw== processing > Argyria Updated: Sep 12, 2017 Author: Kamila K Padlewska, MD (...) , PhD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Argyria Overview Background Argyria results from prolonged contact with or ingestion of silver salts. Argyria is characterized by gray to gray-black staining of the skin and mucous membranes produced by silver deposition. Silver may be deposited in the skin either from industrial exposure or as a result of medications containing silver salts. See the image below. A 92-year-old asymptomatic white man

2014 eMedicine.com

12. Argyria (Treatment)

Argyria (Treatment) Argyria Treatment & Management: Medical Care, Surgical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTEyMS10cmVhdG1lbnQ= processing > Argyria Treatment & Management Updated: Sep 12 (...) , 2017 Author: Kamila K Padlewska, MD, PhD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Argyria Treatment Medical Care Treatment with depigmenting preparations is not satisfactory; however, according to some reports, 5% hydroquinone treatment may reduce the number of silver granules in the upper dermis and around sweat glands and diminish the number of melanocytes. Chelation attempts to remove silver from the body have been unsuccessful. Sunscreens and opaque

2014 eMedicine.com

13. Argyria mimicking a blue nevis: dermoscopy features (PubMed)

Argyria mimicking a blue nevis: dermoscopy features Argyria is a rare disease caused by prolonged skin contact with silver. Localized cases have been described regarding the use of topical medications, and trauma with objects containing this metal such as acupuncture needles and jewelry. Clinically, a macule or a patch, round or oval, appears in the infected area, with a characteristic bluey-gray color. To our knowledge this is the first time that this clinical condition has been described

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2013 Anais brasileiros de dermatologia

14. Argyria

Argyria Argyria Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Argyria Argyria Aka: Argyria , Silver Poisoning From Related Chapters (...) II. Pathophysiology Excessive oral silver intake Results in silver salt deposition in skin III. Symptoms Asymptomatic IV. Signs Permanent blue to bronze discoloration of skin, mucosa Darker coloration where skin exposed to light Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Argyria." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Argyria

2015 FP Notebook

15. Successful treatment of argyria using a low-fluence Q-switched 1064-nm Nd:YAG laser. (PubMed)

Successful treatment of argyria using a low-fluence Q-switched 1064-nm Nd:YAG laser. Argyria is a rare skin disease caused by cutaneous deposits of silver granules as a result of exposure to silver substrates or ingestion of silver salt. This pigmentation change causes cosmetic problems, and there was previously no recognized effective treatments for argyria.To evaluate the treatment effect of a low-fluence Q-switched 1064-nm Nd:YAG laser on argyria.Case report of a 49-year-old with a history (...) of ingestion of a colloidal silver solution daily for approximately one year as a traditional remedy.After seven sessions of treatment, the patient's skin color returned to normal.A low-fluence Q-switched 1064-nm Nd:YAG laser provided safe and effective treatment for the skin discoloration associated with argyria.© 2011 The International Society of Dermatology.

2011 International Journal of Dermatology

16. Occupational Argyria (PubMed)

Occupational Argyria 19992943 2010 06 24 2010 06 24 0035-9157 37 11 1944 Sep Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Occupational Argyria. 648-9 Wigley J E JE Deville P M PM eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1944 9 1 0 0 1944 9 1 0 1 ppublish 19992943 PMC2181032

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1944 Proceedings of the Royal Society of Medicine

17. The Use of BAL in Generalized Argyria (PubMed)

The Use of BAL in Generalized Argyria 18109373 2007 12 27 2018 12 01 0008-1264 70 2 1949 Feb California medicine Calif Med The use of BAL in generalized argyria. 133 KLECKNER M S MS Jr eng Journal Article United States Calif Med 0410260 0008-1264 0 Coloring Agents 0 Silver Compounds 3M4G523W1G Silver OM Argyria Coloring Agents Humans Silver toxicity Silver Compounds 4916:588v SILVER/toxicity 1949 2 1 0 0 2008 1 17 9 0 1949 2 1 0 0 ppublish 18109373 PMC1643584 J Clin Invest. 1946 Jul;25(4):549

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1949 California Medicine

18. An Electron Microscopic Study of Human Generalized Argyria (PubMed)

An Electron Microscopic Study of Human Generalized Argyria 13986364 1998 11 01 2018 12 01 0002-9440 42 1963 Mar The American journal of pathology Am. J. Pathol. An electron microscopic study of human generalized argyria. 293-9 PROSE P H PH eng Journal Article United States Am J Pathol 0370502 0002-9440 OM Argyria Electrons Humans Microscopy, Electron Multiple Myeloma Nephrosis Pneumonia Pneumonia, Pneumococcal ARGYRIA MULTIPLE MYELOMA NEPHROSIS PNEUMONIA, LOBAR 1963 3 1 1963 3 1 0 1 1963 3 1 0

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1963 The American journal of pathology

19. Experimental Argyria: A Model For Basement Membrane Studies (PubMed)

Experimental Argyria: A Model For Basement Membrane Studies 5135534 1972 03 24 2018 11 13 0007-1021 52 6 1971 Dec British journal of experimental pathology Br J Exp Pathol Experimental argyria: a model for basement membrane studies. 589-93 Walker F F eng Journal Article England Br J Exp Pathol 0372543 0007-1021 059QF0KO0R Water 3M4G523W1G Silver IM Animals Argyria pathology Basement Membrane anatomy & histology cytology pathology Eye cytology Kidney anatomy & histology cytology Liver cytology

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1971 British journal of experimental pathology

20. Argyria (PubMed)

Argyria 19974265 2010 06 24 2010 06 24 0035-9157 3 Dermatol Sect 1910 Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Argyria. 75-6 Weber F P FP Norman R H RH eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1910 1 1 0 0 1910 1 1 0 1 ppublish 19974265 PMC1960903

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1910 Proceedings of the Royal Society of Medicine

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