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Aphasia

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61. Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting. Full Text available with Trip Pro

Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting.

2017 Lancet Controlled trial quality: predicted high

62. A case report on crossed aphasia in dextrals: Consideration about clinical features and neural network. Full Text available with Trip Pro

A case report on crossed aphasia in dextrals: Consideration about clinical features and neural network. The term crossed aphasia in dextrals (CAD) describes aphasia following a right hemisphere lesion in right-handed subjects. The diagnostic criteria for CAD, defined on the basis of clinical cases observed over the years, are aphasia; lesion in right hemisphere; strong preference for right hand use without familial history of left handedness; structural integrity of left hemisphere; and absence (...) of brain damage in childhood. The studies of CAD have mainly been focused on the neurobiological mechanisms underlying the functional neurocognitive lateralization and organization of the brain, such as a dissociation between language and handedness, language and praxis, or other cognitive functions.Patient concerns: We described a case of a patient affected by an aphasic syndrome following cerebral hemorrhage located in right hemisphere.Considering the correlation between clinical data

2019 Medicine

63. A systematic review of gesture treatments for post-stroke aphasia

A systematic review of gesture treatments for post-stroke aphasia A systematic review of gesture treatments for post-stroke aphasia A systematic review of gesture treatments for post-stroke aphasia Rose ML, Raymer AM, Lanyon LE, Attard MC CRD summary The authors concluded that there was some evidence of a benefit from combined gesture plus verbal treatment for some individuals with aphasia after a stroke. It was unclear whether this benefit was greater than that produced by verbal treatment (...) alone. The authors' cautious conclusions reflect the quality and amount of evidence presented. Authors' objectives To evaluate the effects of gesture training for patients with aphasia after a stroke. Searching MEDLINE, CINAHL, PsycINFO, EMBASE, Cochrane Database of Systematic Reviews, and Clinical Aphasiology Conference archives were searched to September 2012; search terms were reported. Google Scholar was used to search the Internet. Reference lists of retrieved studies were checked. Study

2013 DARE.

64. Therapeutic interventions for aphasia initiated more than six months post stroke: a review of the evidence Full Text available with Trip Pro

Therapeutic interventions for aphasia initiated more than six months post stroke: a review of the evidence Therapeutic interventions for aphasia initiated more than six months post stroke: a review of the evidence Therapeutic interventions for aphasia initiated more than six months post stroke: a review of the evidence Allen L, Mehta S, McClure JA, Teasell R CRD summary The authors concluded that there was evidence to support the use of several treatments for chronic aphasia post-stroke (...) , but further research was required. Most individual interventions were assessed by only one small study, reducing the reliability of the results, but the authors' overall conclusion is supported by the limited evidence available. Authors' objectives To assess the effectiveness of therapeutic interventions for aphasia, initiated more than six months post-stroke. Searching Multiple databases were searched for English language studies, including MEDLINE, EMBASE, CINAHL and Scopus; search terms were reported

2012 DARE.

65. Stress and Depression Scales in Aphasia: Relation between the Aphasia Depression Rating Scale, Stroke Aphasia Depression Questionnaire-10, and the Perceived Stress Scale Full Text available with Trip Pro

patients with aphasia. The second aim was to evaluate the relation between these scales and a measure of perceived stress.Twenty-five (16 male; 9 female) individuals with history of left hemisphere cerebrovascular accident (CVA) were assessed for depression and perceived stress using the Stroke Aphasic Depression Questionnaire-10 (SADQ-10), the Aphasia Depression Rating Scale (ADRS), and the Perceived Stress Scale (PSS).SADQ-10 and ADRS ratings were strongly correlated with each other (r = 0.708, p (...) Stress and Depression Scales in Aphasia: Relation between the Aphasia Depression Rating Scale, Stroke Aphasia Depression Questionnaire-10, and the Perceived Stress Scale Assessment and diagnosis of post-stroke depression (PSD) among patients with aphasia presents unique challenges. A gold standard assessment of PSD among this population has yet to be identified.The first aim was to investigate the association between two depression scales developed for assessing depressive symptoms among

2016 Topics in stroke rehabilitation

66. Combining rTMS With Intensive Language-Action Therapy in Chronic Aphasia: A Randomized Controlled Trial. Full Text available with Trip Pro

Combining rTMS With Intensive Language-Action Therapy in Chronic Aphasia: A Randomized Controlled Trial. Neuromodulation technologies, such as transcranial magnetic stimulation (TMS), are promising tools for neurorehabilitation, aphasia therapy included, but not yet in common clinical use. Combined with behavioral techniques, in particular treatment-efficient Intensive Language-Action Therapy (ILAT, previously CIAT or CILT), TMS could substantially amplify the beneficial effect (...) of such behavioral therapy alone (Thiel et al., 2013; Martin et al., 2014; Mendoza et al., 2016; Kapoor, 2017). In this randomized study of 17 subjects with post-stroke aphasia in the chronic stage, we studied the combined effect of ILAT and 1-Hz placebo-controlled navigated repetitive TMS (rTMS) to the right-hemispheric inferior frontal cortex-that is, to the anterior part of the non-dominant hemisphere's homolog Broca's area (pars triangularis). Patients were randomized to groups A and B. Patients in group

2018 Frontiers in neuroscience Controlled trial quality: uncertain

67. Technology-enhanced writing therapy for people with aphasia: results of a quasi-randomized waitlist controlled study. Full Text available with Trip Pro

Technology-enhanced writing therapy for people with aphasia: results of a quasi-randomized waitlist controlled study. Acquired writing impairment, or dysgraphia, is common in aphasia. It affects both handwriting and typing, and may recover less well than other aphasic symptoms. Dysgraphia is an increasing priority for intervention, particularly for those wishing to participate in online written communication. Effective dysgraphia treatment studies have been reported, but many did not target (...) of writing, which was administered in handwriting and on a computer with assistive technology enabled. Secondary measures were: The Boston Naming Test (written version), Communication Activities of Daily Living-2, Visual Analogue Mood Scales (Sad question), and the Assessment of Living with Aphasia. Analyses of variance (ANOVA) were used to examine change on the outcome measures over two time points, between which the immediate group had received therapy but the delayed group had not. Pre-therapy, post

2018 International Journal of Language & Communication Disorders Controlled trial quality: uncertain

68. Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia. (Abstract)

Effect of type of language therapy on expressive language skills in patients with post-stroke aphasia. Constraint-induced (language) aphasia therapy (CIAT), based on constraint usage of the language channel only, massed practice and shaping through therapeutic language games, has been suggested as a more efficient therapy approach than traditional aphasia therapies.To examine the comparative efficacy of CIAT and a traditional therapy approach on expressive language ability, with the intensity (...) of therapy controlled and matched, in the treatment of post-stroke aphasia.Two successive 4-week blocks of intense (1 h, 5 days a week) of aphasia therapy programmes were delivered in a randomized within-subject crossover design: one therapy block consisted of stimulation aphasia therapy (SAT, a common traditional therapy approach), another of CIAT. Twenty consecutive patients, up to 1 year after stroke, were randomly assigned either to have SAT followed by CIAT (S1C2 group) or to have CIAT followed

2018 International Journal of Language & Communication Disorders Controlled trial quality: uncertain

69. Telerehabilitation Combined Speech-Language and Cognitive Training Effectively Promoted Recovery in Aphasia Patients. Full Text available with Trip Pro

Telerehabilitation Combined Speech-Language and Cognitive Training Effectively Promoted Recovery in Aphasia Patients. The present study investigated the efficacy of a computerized intervention for aphasia that combined speech-language and cognitive training delivered on an inpatient unit or via telerehabilitation to discharged patients. Forty inpatient and discharged aphasia patients were recruited and randomly assigned to the training group or control group. Computerized speech-language (...) and cognitive training was provided for 14 days to the inpatients and 30 days to the discharged patients. Compared with the control group, training group had significantly more improved language function as assessed by the Western Aphasia Battery (WAB) and practical communication skills as assessed by the Communicative Abilities in Daily Living Test (CADL). It was also found that the positive effects of the computerized training when delivered via telerehabilitation to the discharged group were smaller than

2018 Frontiers in psychology Controlled trial quality: uncertain

70. 'What's cooking?' A comparison of an activity-oriented and a table-top programme of therapy on the language performance of people with aphasia. Full Text available with Trip Pro

'What's cooking?' A comparison of an activity-oriented and a table-top programme of therapy on the language performance of people with aphasia. Many people with aphasia have word-finding difficulties, with some showing particular difficulties with verbs. Picture-naming therapy is often used to improve naming, but gains are usually limited to therapy items and do not transfer to conversation. Therapy where words are produced in sentences and in real-life activities may be more effective.The (...) in spoken narratives. Participants predominantly chose positive terms to describe their experience of the programme, but did not prefer one therapy over the other.Preliminary findings suggest that an activity-oriented therapy approach, whether it involves carrying out tasks or paper-based activities, can result in clinically meaningful improvements for people with chronic aphasia. Further research using a randomized control trial is required to determine whether cooking therapy alone is effective.© 2018

2018 International Journal of Language & Communication Disorders Controlled trial quality: uncertain

71. tDCS over the motor cortex improves lexical retrieval of action words in poststroke aphasia. Full Text available with Trip Pro

tDCS over the motor cortex improves lexical retrieval of action words in poststroke aphasia. One-third of stroke survivors worldwide suffer from aphasia. Speech and language therapy (SLT) is considered effective in treating aphasia, but because of time constraints, improvements are often limited. Noninvasive brain stimulation is a promising adjuvant strategy to facilitate SLT. However, stroke might render "classical" language regions ineffective as stimulation sites. Recent work showed (...) the effectiveness of motor cortex stimulation together with intensive naming therapy to improve outcomes in aphasia (Meinzer et al. 2016). Although that study highlights the involvement of the motor cortex, the functional aspects by which it influences language remain unclear. In the present study, we focus on the role of motor cortex in language, investigating its functional involvement in access to specific lexico-semantic (object vs. action relatedness) information in poststroke aphasia. To this end, we

2018 Journal of neurophysiology Controlled trial quality: uncertain

72. The Acute Aphasia IMplementation Study (AAIMS): a pilot cluster randomized controlled trial. (Abstract)

The Acute Aphasia IMplementation Study (AAIMS): a pilot cluster randomized controlled trial. Effective implementation strategies to improve speech and language therapists' (SLTs) aphasia management practices are needed. Australian SLTs working in the acute setting have reported inconsistent implementation of post-stroke aphasia guideline recommendations. Therefore, implementation efforts to address these gaps are necessary. However, little is known about the effectiveness of behaviour-change (...) strategies in SLTs providing acute aphasia management.This study designed and tested the feasibility, acceptability and potential effectiveness of a tailored implementation strategy to improve acute SLTs' uptake of evidence in two areas of practice: aphasia-friendly information provision; and collaborative goal setting.A pilot cluster randomized controlled trial design was used (retrospective trial registration number ACTRN12618000170224). Four acute SLT teams were randomly assigned to receive either

2018 International Journal of Language & Communication Disorders Controlled trial quality: uncertain

73. Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial. Full Text available with Trip Pro

Melodic intonation therapy in post-stroke nonfluent aphasia: a randomized pilot trial. To collect data to estimate the sample size of a definitive randomized controlled trial to evaluate the effects of Melodic Intonation Therapy in post-stroke nonfluent aphasia.A randomized, crossover, interventional pilot trial.Departments of Neurology and Rehabilitation from a university general hospital.Stroke survivors with post-stroke nonfluent aphasia.Patients randomized to group 1 had treatment (...) with Melodic Intonation Therapy first (12 sessions over six weeks) followed by no treatment; the patients in group 2 started active treatment between three and six months after their inclusion in the study, serving as waiting list controls for the first phase.The Communicative Activity Log (CAL) questionnaire and the Boston Diagnostic Aphasia Examination (BDAE) were evaluated at baseline, and at six and 12 weeks.Twenty patients were included. Four of the patients allocated to group 2 crossed over to group

2018 Clinical rehabilitation Controlled trial quality: predicted high

74. Transcranial Cerebellar Direct Current Stimulation Enhances Verb Generation but Not Verb Naming in Poststroke Aphasia. Full Text available with Trip Pro

Transcranial Cerebellar Direct Current Stimulation Enhances Verb Generation but Not Verb Naming in Poststroke Aphasia. Although the role of the cerebellum in motor function is well recognized, its involvement in the lexical domain remains to be further elucidated. Indeed, it has not yet been clarified whether the cerebellum is a language structure per se or whether it contributes to language processing when other cognitive components (e.g., cognitive effort, working memory) are required (...) by the language task. Neuromodulation studies on healthy participants have suggested that cerebellar transcranial direct current stimulation (tDCS) is a valuable tool to modulate cognitive functions. However, so far, only a single case study has investigated whether cerebellar stimulation enhances language recovery in aphasic individuals. In a randomized, crossover, double-blind design, we explored the effect of cerebellar tDCS coupled with language treatment for verb improvement in 12 aphasic individuals

2018 Journal of cognitive neuroscience Controlled trial quality: uncertain

75. Effects of different frequencies of repetitive transcranial magnetic stimulation in stroke patients with non-fluent aphasia: a randomized, sham-controlled study. (Abstract)

Effects of different frequencies of repetitive transcranial magnetic stimulation in stroke patients with non-fluent aphasia: a randomized, sham-controlled study. The purpose of this study was to compare the efficacy of repetitive transcranial magnetic stimulation (rTMS) applied at different frequencies to the contra-lesional hemisphere to optimize the treatment of post-stroke non-fluent aphasia.Patients with post-stroke non-fluent aphasia were divided randomly into four groups: a high-frequency (...) by the Chinese version of the Western Aphasia Battery (WAB).When measured immediately post-treatment, as well as at 2 months post-treatment, the LF-rTMS group exhibited a more marked improvement than the HF-rTMS group in spontaneous speech, auditory comprehension, and aphasia quotients (AQ). Compared to the control group, the HF-rTMS cohort exhibited significant improvement at 2-months post-treatment in repetition and AQ.LF-rTMS and HF-rTMS are both beneficial to the recovery of linguistic function

2018 Neurological research Controlled trial quality: uncertain

76. Transcranial direct current stimulation: a study on naming performance in aphasic individuals. Full Text available with Trip Pro

Transcranial direct current stimulation: a study on naming performance in aphasic individuals. Compare the results in naming tasks of after-stroke aphasic individuals divided into active and placebo groups pre- and post-transcranial direct current stimulation.A double-blind, randomized, controlled study conducted with 14 individuals. Patients underwent five 20-min sessions with stimulation of 2mA's on consecutive days. The cathode was placed over the Broca's homologous area and the anode (...) ) is a method that can improve the rehabilitation of patients with anomic and Broca's aphasia after stroke, and that language strategies should be considered in the analysis of naming task responses.

2018 CoDAS Controlled trial quality: uncertain

77. Comparison of two configurations of transcranial direct current stimulation for aphasia treatment. Full Text available with Trip Pro

Comparison of two configurations of transcranial direct current stimulation for aphasia treatment. To compare 2 configurations of transcranial direct current stimulation (tDCS) for treatment of aphasia.Randomized cross-over study.Patients with chronic post-stroke aphasia (n = 13).tDCS was combined with word-finding therapy in 3 single sessions. In session 1, sham-tDCS/pseudo-stimulation was applied. In sessions 2 and 3, 2 active configurations were provided in random order: anodal tDCS over (...) active tDCS; either in the l-IFG condition (n = 4; 31%) or in both the l-IFG and l-STG conditions (n = 2; 15%). On the untrained items there was no improvement (median = 0%; interquartile range  = 0-0).This randomized cross-over single-session protocol to determine an optimal tDCS configuration for treatment of aphasia suggests that only performance on trained items can be used as guidance for configuration, and that it is relevant for half of the patients. For this subgroup, the l-IFG configuration

2018 Journal of Rehabilitation Medicine Controlled trial quality: uncertain

78. Computerized Training in Poststroke Aphasia: What About the Long-Term Effects? A Randomized Clinical Trial. (Abstract)

Computerized Training in Poststroke Aphasia: What About the Long-Term Effects? A Randomized Clinical Trial. Poststroke aphasia is a very disabling disorder, which may affect speech expression, comprehension, and reading or writing. Treatment of aphasia should be initiated as soon as possible after the brain injury; however, the improvement of language functions can occur also in the chronic phase.Thirty-two patients were randomly assigned to either an experimental group (17 patients) treated (...) was significant only concerning Functional Independence Measure and ideomotor praxis. Notably, the improvements in cognitive and language functions were maintained at 3-month follow-up only in the experimental group.The software Power-Afa can be considered a valuable tool in improving the linguistic and cognitive recovery in patients affected by poststroke aphasia in the chronic phase. Further studies with larger samples and longer follow-up periods are needed to confirm such promising findings.Copyright ©

2018 Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association Controlled trial quality: uncertain

79. Further Evidence of the Positive Influence of Repetitive Transcranial Magnetic Stimulation on Speech and Language in Patients with Aphasia after Stroke: Results from a Double-Blind Intervention with Sham Condition. (Abstract)

Further Evidence of the Positive Influence of Repetitive Transcranial Magnetic Stimulation on Speech and Language in Patients with Aphasia after Stroke: Results from a Double-Blind Intervention with Sham Condition. After a stroke, up to 20% of patients suffer from aphasia. The preferred treatment for stroke-related aphasia (SRA) is regular speech and language training (SLT). In the present study, we investigated to what extent adjuvant repetitive transcranial magnetic stimulation (rTMS) might (...) enhance recovery. While there is growing evidence of the positive effect of adjuvant rTMS on aphasia, no study has yet been based on an Iranian sample.A total of 12 patients (mean age: 55 years; right-handed; 7 women) underwent treatment for SRA 1 month after stroke. The standard treatment consisted of regular 45-min SLT sessions 5 times a week for 2 consecutive weeks. Additionally, patients were randomly assigned either to adjuvant rTMS (5 times a week for 30 min) or to a sham condition (5 times

2018 Neuropsychobiology Controlled trial quality: uncertain

80. Non-invasive brain stimulation and computational models in post-stroke aphasic patients: single session of transcranial magnetic stimulation and transcranial direct current stimulation. A randomized clinical trial. Full Text available with Trip Pro

Non-invasive brain stimulation and computational models in post-stroke aphasic patients: single session of transcranial magnetic stimulation and transcranial direct current stimulation. A randomized clinical trial. Patients undergoing the same neuromodulation protocol may present different responses. Computational models may help in understanding such differences. The aims of this study were, firstly, to compare the performance of aphasic patients in naming tasks before and after one session (...) at Faculdade de Ciências Médicas da Santa Casa de São Paulo.Patients with aphasia received one session of tDCS, TMS or sham stimulation. The time taken to name pictures and the response time were evaluated before and after neuromodulation. Selected patients from the first intervention underwent a computational model stimulation procedure that simulated tDCS.The results did not indicate any statistically significant differences from before to after the stimulation.The computational models showed different

2018 Sao Paulo medical journal = Revista paulista de medicina Controlled trial quality: uncertain

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