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Aphasia

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3881. Screening and Treatment of Depression in the Community

Inclusion Criteria: > 60 years without dementia, Major depressive disorder, Bipolar disorder, Dysthymia disorder, Anxiety disorder, Mania/hypomania Exclusion Criteria: Severe post-stroke dementia or aphasia, History of mania, psychiatric consultation or admission to hospital in past 3 months, MMSE score <18, Fully dependent at 3 or more basic activities of daily living, Very high BDI score (>=30), Serious suicidal risk, Current psychotic symptoms, Current alcohol abuse, Very high GDS score (>=12

2007 Clinical Trials

3882. Brain Oxygenation Monitoring in Patients Undergoing Coronary Artery Bypass Surgery

Volunteers: No Criteria Inclusion Criteria: Primary coronary artery bypass surgery Ages 18-90 Voluntary participation with signed informed consent Exclusion Criteria: An unwillingness to participate in the study Inability to obtain informed consent Expressive or receptive aphasia Inability to correctly perform the neurocognitive tests preoperatively Inability to correctly perform the saccadic and anti-saccadic eye movement tests preoperatively Non-English speaking candidates Patients for whom it is known

2005 Clinical Trials

3883. Role of the Right Brain in Recovery of Language Function in Chronic Stroke

will include patients with thromboembolic non-hemorrhagic hemispheric lesions and with hemorrhagic hemispheric lesions (as documented by CT or MRI) at least 12 months after the stroke. We will choose subjects with chronic stable aphasia, that initially presented with severe aphasia and have partially recovered. Assessment of the initial functional state will be taken either from patient report or medical records. All of the aphasic patients are already known to the investigators from the NIDCD. EXCLUSION (...) ) Information provided by: National Institutes of Health Clinical Center (CC) Study Details Study Description Go to Brief Summary: This study will examine in healthy individuals and in patients with aphasia (a language disturbance that is usually caused by stroke, brain disease, or injury) which parts of the brain are involved in naming everyday objects. In most people, language and speech originate in the left side of the brain. When this side of the brain is damaged, language function is often impaired

2004 Clinical Trials

3884. Direct Current Brain Polarization in Frontotemporal Dementia

table for additonal information ClinicalTrials.gov Identifier: Other Study ID Numbers: 040122 04-N-0122 First Posted: February 13, 2004 Last Update Posted: March 4, 2008 Last Verified: August 2005 Keywords provided by National Institutes of Health Clinical Center (CC): Treatment Transcranial Stimulation Frontal Lobe Pick's Disease Cognitive Impairment Dementia Frontotemporal Dementia FTD Additional relevant MeSH terms: Layout table for MeSH terms Dementia Frontotemporal Dementia Aphasia, Primary (...) Progressive Pick Disease of the Brain Brain Diseases Central Nervous System Diseases Nervous System Diseases Neurocognitive Disorders Mental Disorders Frontotemporal Lobar Degeneration TDP-43 Proteinopathies Neurodegenerative Diseases Proteostasis Deficiencies Metabolic Diseases Aphasia Speech Disorders Language Disorders Communication Disorders Neurobehavioral Manifestations Neurologic Manifestations Signs and Symptoms

2004 Clinical Trials

3885. L-Carnitine to Treat Fatigue in AIDS Patients

or alcohol use or dependence History of any central nervous system disease involving the brain that may put the patient at risk for seizure (e.g., primary or metastatic brain tumor, stroke) or history of seizure History of dementia, aphasia, or other deficits of cognition or speech/language function Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided

2004 Clinical Trials

3886. Assessing the Effectiveness of Communication Therapy in the North West (The ACT NoW Pilot Study)

: NHS Health Technology Assessment Programme Information provided by: NHS Health Technology Assessment Programme Study Details Study Description Go to Brief Summary: This study investigates the effectiveness and cost-effectiveness of speech and language therapy for adults who suffer communication difficulties following a stroke. Condition or disease Intervention/treatment Phase Speech or Language Impairment Following Stroke Procedure: Speech and Language therapy for dysarthria and/or aphasia (...) effectiveness and net benefit of the intervention group compared to the control group from a societal perspective. The qualitative study will examine service users' and carers' perspectives on the process and effects of Speech and Language Therapy or the control treatment. Sample Group: Adults with dysarthria or aphasia, seen early after admission to hospital with a stroke. Exclusions: subarachnoid haemorrhage, progressive dementia, expected recovery without therapy. Study Design Go to Layout table

2005 Clinical Trials

3887. Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

2008 Keywords provided by Assistance Publique - Hôpitaux de Paris: Amyotrophic lateral sclerosis Frontotemporal dementia Mutations spectrum Linkage studies Genetic epidemiology Additional relevant MeSH terms: Layout table for MeSH terms Sclerosis Dementia Motor Neuron Disease Amyotrophic Lateral Sclerosis Frontotemporal Dementia Aphasia, Primary Progressive Pick Disease of the Brain Pathologic Processes Brain Diseases Central Nervous System Diseases Nervous System Diseases Neurocognitive Disorders (...) Mental Disorders Neurodegenerative Diseases Neuromuscular Diseases Spinal Cord Diseases TDP-43 Proteinopathies Proteostasis Deficiencies Metabolic Diseases Frontotemporal Lobar Degeneration Aphasia Speech Disorders Language Disorders Communication Disorders Neurobehavioral Manifestations Neurologic Manifestations Signs and Symptoms

2005 Clinical Trials

3888. Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients

information Ages Eligible for Study: 50 Years to 95 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Chronic obstructive pulmonary disease by American Thoracic Society criteria Major depression by DSM-IV criteria 17-item Hamilton score >14 English speaking Exclusion Criteria: Inability to give informed consent MiniMental score <24 Aphasia Nursing home placement after discharge Contacts and Locations Go to Information from the National

2005 Clinical Trials

3889. Treatment of Depression in the Elderly

. deafness, blindness, severe aphasia Patients who cannot speak Danish well enough to make psychometric assessment possible and meaningful Patients with congenital or early acquired intellectual deficits Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number

2005 Clinical Trials

3890. Treatment Study of Frontotemporal Dementia

Dementia or Primary Progressive Aphasia. Ages 45 to 95 years old. Mild-to-moderate (CDR 1 to 2) FTD with an assigned durable power of attorney. EXCLUSION CRITERIA: Diagnosis of any form of dementia besides FTD, including AD, Lewy body dementia, vascular dementia, dementia associated with Parkinson's disease, Corticobasal Degeneration and Progressive Supranuclear Palsy. Severe dementia (CDR 3). Known allergy or serious adverse reaction to quetiapine or dextroamphetamine. Patient is already receiving (...) Frontotemporal Dementia Aphasia, Primary Progressive Pick Disease of the Brain Frontotemporal Lobar Degeneration Brain Diseases Central Nervous System Diseases Nervous System Diseases Neurocognitive Disorders Mental Disorders TDP-43 Proteinopathies Neurodegenerative Diseases Proteostasis Deficiencies Metabolic Diseases Aphasia Speech Disorders Language Disorders Communication Disorders Neurobehavioral Manifestations Neurologic Manifestations Signs and Symptoms

2004 Clinical Trials

3891. Diabetes Telemedicine Consultation: A Systems Improvement Intervention

) Current prescription of insulin or an oral hypoglycemic agent 2) A1c > 7.0% 3) fasting glucose levels > 130 mg/dl 4) referred to see a consultant and are seen during the active intervention phase. Patients with either Type I or Type II DM will be included A Primary Care Provider for a Cleveland CBOC Exclusion Criteria: 1) primary care obtained at more than one site (based on stop codes with evidence of more than 1 CBOC involved in care during the last 6 months) 2) documented dementia, aphasia

2005 Clinical Trials

3892. Telephone Disease Management At-Risk Drinking (TDM II)

diagnosis of current alcohol dependence current hallucinations and delusions current symptoms of PTSD a history of mania or hypomania. have adequate hearing to participate in telephone assessments and access to a telephone. Subjects will also show an absence of other barriers to verbal communication (e.g., aphasia) and will be cognitively intact (Brief Orientation Memory and Concentration task greater than 15 for those over age 54). not actively participating in specialized addiction treatment within

2005 Clinical Trials

3893. Fluoxetine on Motor Rehabilitation After Ischemic Stroke

Depression requiring pharmacological treatment Previous stroke with motor relapse Fugl Meyer Motor Scale > 55 Modified Rankin Scale = 0 or 6 Patients needing carotid surgery within 3 months Aphasia preventing correct evaluation of motor and depression scales. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study

2008 Clinical Trials

3894. Angioplasty of an Idiopathic Intracranial Arterial Stenosis (Full text)

intracranial stenosis which was refractory to medical therapy and was successfully treated with percutaneous transluminal angioplasty. The presenting symptoms included multiple episodes of aphasia and right-sided weakness as well as a left basal ganglia infarct. The patient underwent treatment with two intracranial angioplasty procedures. There was a recurrence of the stenosis and symptoms following the first procedure. However, after a second treatment with a slightly larger balloon, flow in the MCA

2007 Interventional Neuroradiology PubMed abstract

3895. Prevalence and misdiagnosis of chronic heart failure in nursing home residents: the role of B-type natriuretic peptides (Full text)

but their use in nursing home residents is limited. We examined the number of misdiagnoses, the CHF prevalence and the role of natriuretic peptide.Residents in one centre without aphasia, cognitive impairments or metastatic cancer were screened for CHF; the natriuretic peptide levels were measured separately.Of the 150 residents, 103 (64%) were included (79+/-11 years). The diagnosis of CHF was established in 24 of these 103 residents with NTproBNP 1871 (IQR 539 to 4262) and BNP 194 (IQR 92 to 460) pg/ml

2008 Netherlands Heart Journal PubMed abstract

3896. Clinical profile of venomous snake bites in north Indian Military Hospital (Full text)

administration of ASV. All patients recovered without sequelae. Soldiers during military exercise are vulnerable to snakebites. Neurotoxic snakebites predominate in our study and usually present with autonomic features along with headache, abdominal pain, ptosis, diplopia and dysphasia. Preventive measures to minimize snake bites and planned treatment regimens should be emphasized among medical and military personnel deployed in the field operations.

2008 Journal of Emergencies, Trauma and Shock PubMed abstract

3897. What Is the Evidence for Use Dependent Learning After Stroke? (Full text)

United States P01 NS046588-05 NS NINDS NIH HHS United States P51-NS046588 NS NINDS NIH HHS United States Journal Article Research Support, N.I.H., Extramural Review 2008 12 08 United States Stroke 0235266 0039-2499 IM Aphasia physiopathology therapy Brain physiopathology Communication Humans Language Therapy methods Magnetic Resonance Imaging Stroke physiopathology therapy Verbal Learning physiology 15 2008 12 10 9 0 2009 3 27 9 0 2008 12 10 9 0 ppublish 19064775 STROKEAHA.108.534925 10.1161

2008 Stroke; a journal of cerebral circulation PubMed abstract

3898. Combined transcranial direct current stimulation and robot-assisted arm training in subacute stroke patients: a pilot study. (Abstract)

Aphasie Test.No major side effects occurred. Arm function of three patients (two with a subcortical lesion) improved significantly, with FM scores increasing from 6 to 28, 10 to 49 and 11 to 48. In the remaining seven patients, all with cortical lesions, arm function changed little, FM scores did not increase more than 5 points. Unexpectedly, aphasia improved in 4 patients.These procedures are safe, and easy to use in a clinical setting. In future studies, patients should be stratified by degree (...) of arm weakness and lesion site, also the unexpected aphasia improvement warrants following-up.

2007 Restorative neurology and neuroscience

3899. Gliadel wafers in the treatment of malignant glioma: a systematic review. (Full text)

adverse events were convulsions, confusion, brain edema, infection, hemiparesis, aphasia, and visual field defects.Gliadel is an option for selected patients with newly diagnosed malignant glioma where a near gross total resection is possible. No evidence is available comparing Gliadel with systemic therapy, and a decision to combine Gliadel with systemic therapy should be made for patients individually. The patient population that would benefit from Gliadel (age, histology, and performance status

2007 Current oncology (Toronto, Ont.) PubMed abstract

3900. Noninvasive brain stimulation improves language learning. (Abstract)

Noninvasive brain stimulation improves language learning. Anodal transcranial direct current stimulation (tDCS) is a reliable technique to improve motor learning. We here wanted to test its potential to enhance associative verbal learning, a skill crucial for both acquiring new languages in healthy individuals and for language reacquisition after stroke-induced aphasia. We applied tDCS (20 min, 1 mA) over the posterior part of the left peri-sylvian area of 19 young right-handed individuals

2008 Journal of cognitive neuroscience

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