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Aphasia

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3761. Factors affecting completion of the SF-36 in older people. Full Text available with Trip Pro

of individual questions and time taken to complete.severe functional impairment (Barthel index < or = 12) was found in 22.4% (51/228), cognitive impairment in 54.1% (132/244), depressed mood in 77.0% (151/196) and visuospatial dysfunction in 71.3% (134/188). The median number of impairments was three (interquartile range 1-4). Specific physical impairments were visual in 13.2% (31/235), hearing in 30.2% (74/245), impaired manual dexterity in 18.0% (44/245) and dysphasia in 23% (55/239). In multivariate

2006 Age and ageing

3762. Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage. (Abstract)

in the nimodipine group. Good recovery evaluated by the Glasgow Outcome Scale was achieved by 23 of 33 patients in the fasudil group and 19 of 34 patients in the nimodipine group. Both drugs significantly improved consciousness levels and neurological deficits such as aphasia. However, fasudil hydrochloride improved motor disturbance more than nimodipine. Adverse reactions occurred in 13 of 37 patients receiving fasudil hydrochloride and 15 of 35 patients receiving nimodipine. There were no serious adverse

2006 Neurologia medico-chirurgica Controlled trial quality: uncertain

3763. Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia. (Abstract)

, and hemolytic anemia; Grade 3 nervous system AEs included aphasia; peripheral neuropathy, not otherwise specified; and peripheral sensory neuropathy. Although no objective responses were achieved in patients with fludarabine-refractory B-cell CLL, single-agent bortezomib demonstrated biologic activity. In view of the evidence for its activity, further exploration of bortezomib in combination with other agents is warranted.

2006 Cancer Controlled trial quality: uncertain

3765. D2 gastrectomy -- a safe operation in experienced hands. (Abstract)

%) patients developed dysphasia, of which two (6%) had anastomotic stricture requiring dilatation. We feel D2 gastrectomy with splenectomy and distal pancreatectomy when performed electively is a safe procedure in experienced hands. Oesophago-jejunal anastomosis can be safely performed using circular stapler.

2005 International journal of clinical practice

3766. Temporal dissociation of early lexical access and articulation using a delayed naming task--an FMRI study. Full Text available with Trip Pro

Temporal dissociation of early lexical access and articulation using a delayed naming task--an FMRI study. Neuroimaging studies of overt speech hold an important practical advantage allowing monitoring of subject performance, particularly valuable in disorders like aphasia. However, speech production is not a monotonic process but a complex sequence of stages. Levelt and colleagues have described these as roughly corresponding to two originally independent systems--conceptual and sensorimotor

2006 Cerebral cortex (New York, N.Y. : 1991) Controlled trial quality: uncertain

3767. Comparing fixed- and randomized-interval spaced retrieval in anomia treatment. (Abstract)

Comparing fixed- and randomized-interval spaced retrieval in anomia treatment. Spaced retrieval (SR) has recently been modified to target anomia in persons with aphasia (PWA). It relies on a strict management of the inter-stimulus interval (ISI) where the time between stimulus presentations is doubled or halved based on response accuracy. Although SR is successful in treating anomia, it remains to be studied whether the strict ISI management is necessary. The present study compared fixed (...) in RISR, is sufficient for successful treatment outcome.Readers will be able to describe the spaced retrieval treatment approach using both fixed- and randomized-interval stimulus schedules, as well as applications of this technique in the treatment of anomia in aphasia.

2005 Journal of communication disorders

3768. [Clinical treatment of apoplectic aphemia with multi-needle puncture of scalp-points in combination with visual-listening-speech training]. (Abstract)

and acupuncture [Dingqu: 1 cun and 2 cun parallel to the line joining Baihui (GV 20) and Qianding (GV 21) respectively on the bilateral sides. Dingqianqu: 1 cun and 2 cun parallel to the line joining GV21 and Xinghui (GV 22) separately on both sides. etc] combined with rehabilitation (Acup+ Rehab) group. Aphasia Battery of Chinese (ABC) was used to assess the patient's speech ability, i.e., aphasia quocient (AQ); The Chinese functional communication (CFCP) test was used to evaluate the patient's daily life (...) speech communication ability, and Boston Diagnostic Aphasia Examination (BDAE) was also conducted to assess the severity of aphasia.After the treatment, the speech ability, oral presentation, listening comprehension, writing ability, AQ index and CFCP were all improved significantly in 3 groups (P < 0.005, 0.01); the total effective rate (85.00%) of Acup+ Rehab group was significantly higher than those of Rehab group (77.78%) and control group (64.71%, P < 0.05, 0.01). The scores of ABC, AQ index

2007 Zhen ci yan jiu = Acupuncture research / [Zhongguo yi xue ke xue yuan Yi xue qing bao yan jiu suo bian ji] Controlled trial quality: uncertain

3769. Stroke: a randomized trial of exercise or relaxation. (Abstract)

Stroke: a randomized trial of exercise or relaxation. To determine the feasibility and effect of exercise training after stroke.Randomized exploratory trial comparing exercise training (including progressive endurance and resistance training) with relaxation (attention control).Interventions were performed in a rehabilitation hospital.Sixty-six independently ambulatory patients (mean age 72, 36 men) without significant dysphasia, confusion, or medical contraindications to exercise training who

2007 Journal of the American Geriatrics Society Controlled trial quality: uncertain

3770. Neural correlates of Dutch Verb Second in speech production. (Abstract)

Neural correlates of Dutch Verb Second in speech production. Dutch speakers with agrammatic Broca's aphasia are known to have problems with the production of finite verbs in main clauses. This performance pattern has been accounted for in terms of the specific syntactic complexity of the Dutch main clause structure, which requires an extra syntactic operation (Verb Second), relative to the basic Subject-Object-Verb order surfacing in Dutch subordinate clauses. We report an fMRI study

2008 Brain and language

3771. The effect of topical application of pure honey on radiation-induced mucositis: a randomized clinical trial. (Abstract)

The effect of topical application of pure honey on radiation-induced mucositis: a randomized clinical trial. Radiation-induced mucositis is an early effect of head and neck radiotherapy. Mucositis can cause ulcers, and patients may experience pain and dysphasia which need treatment. The aim of this study is to evaluate the effect of pure natural honey on radiation induced mucositis.In this randomized single blind (examiner blind) clinical trial 40 patients with head and neck cancer requiring

2008 The journal of contemporary dental practice Controlled trial quality: uncertain

3772. Intraoperative subcortical stimulation mapping of language pathways in a consecutive series of 115 patients with Grade II glioma in the left dominant hemisphere. (Abstract)

paraphasia when stimulated; 2) inferior frontooccipital fasciculus, generating semantic paraphasia when stimulated; 3) subcallosal fasciculus, inducing transcortical motor aphasia during stimulation; 4) frontoparietal phonological loop, eliciting speech apraxia during stimulation; and 5) fibers coming from the ventral premotor cortex, inducing anarthria when stimulated. These structures were preserved, representing the limits of the resection. Despite a transient immediate postoperative worsening, all

2008 Journal of Neurosurgery

3773. Intraoperative mapping of language functions: a longitudinal neurolinguistic analysis. Full Text available with Trip Pro

, including cases both with and without preoperative disturbances. Risk factors for postoperative aphasic disturbance were preoperative aphasia (p<0.0002), intraoperative complications (p<0.02), language-positive sites within the tumor (p<0.001), and nonfrontal lesion location (p<0.001). In patients without a preoperative deficit, a normal (yet submaximal) naming performance was a powerful predictor for an early postoperative aphasic disturbance (p<0.0003). Seven months after treatment 10.9% of the 128 (...) cases without preoperative aphasic disturbances continued to demonstrate new postoperative language disturbances. A total of 17.6% of all cases demonstrated new postoperative language disturbances after 7 months. Risk factors for persistent aphasic disturbance were increased age (>40 years, p<0.02) and preoperative aphasia (p<0.001).Every attempt should be undertaken to preserve language-relevant areas intraoperatively, even when they are located within the tumor. New postoperative deficits resolve

2008 Journal of Neurosurgery

3774. Mesenteric pseudoaneurysm and cerebral stroke as sequelae of infective endocarditis in an adolescent. (Abstract)

and eventual cardiac murmur and was found to have vancomycin-resistant Enterococcus growing as a vegetation on a previously undiagnosed bicuspid aortic valve. He had a cerebral stroke presenting as Broca's aphasia before cardiac surgery, as well as a superior mesenteric artery pseudoaneurysm several days postoperatively. The case highlights some of the serious surgical complications that can occur in young persons with infective endocarditis, as well as many of the problems involved in managing a patient

2008 Journal of Pediatric Surgery

3775. Arcuate fasciculus tractography integrated into Gamma Knife surgery. Full Text available with Trip Pro

malformations adjacent to the AF. Diffusion tensor images were acquired before the frame was affixed to the patient's head and DT tractography images of the AF were created using the authors' original software. The data from DT tractography and stereotactic 3D imaging studies obtained after frame fixation were transported to a treatment planning workstation for GKS and coregistered so that the delivered doses and incidence of posttreatment aphasia could be assessed.The AF could not be depicted in 2 patients (...) who initially presented with motor aphasia caused by hemorrhaging from arteriovenous malformations. During the median follow-up period of 29 months after GKS, aphasia developed in 2 patients: 30 Gy delivered to the frontal portion of the AF caused conduction aphasia in 1 patient, and 9.6 Gy to the temporal portion led to motor aphasia in the other. Speech dysfunction was not observed after a maximum radiation dose of 10.0-16.8 Gy was delivered to the frontal fibers in 4 patients, and 3.6-5.2 Gy

2008 Journal of Neurosurgery

3776. Treatment of a middle cerebral artery giant aneurysm using a covered stent. Case report. (Abstract)

Treatment of a middle cerebral artery giant aneurysm using a covered stent. Case report. The authors report the case of a 60-year-old man harboring a wide-necked giant aneurysm of the M1 segment of the left middle cerebral artery (MCA); his symptoms included transient ischemic attacks characterized by right hemiparesis and aphasia. The aneurysm was treated by placing a covered stent across the orifice of the aneurysm. The 18-month follow-up examination showed a very good outcome, with perfect (...) left MCA patency, no new ischemic lesion, and minor residual aphasia and right hemiparesis. This is the first report in the literature of an MCA aneurysm treated using a covered stent.

2006 Journal of Neurosurgery

3777. Correlation of carotid artery stump pressure and neurologic changes during 474 carotid endarterectomies performed in awake patients. Full Text available with Trip Pro

baseline. Accurate SPs were confirmed by the finding of flatline waveforms after internal carotid artery clamping. Selective shunting was performed when neurologic changes occurred (aphasia, inability to squeeze the contralateral hand, decreased consciousness), regardless of SP. During this same period, 142 patients underwent CEA using GA, and SP was also measured.Shunting was necessary because of neurologic changes in 7.2% (34/474) of all CEAs performed using CBA: 0.9% (3/335) with SPs > or = 50 mm Hg

2005 Journal of Vascular Surgery

3778. Prospective evaluation of electroencephalography, carotid artery stump pressure, and neurologic changes during 314 consecutive carotid endarterectomies performed in awake patients. Full Text available with Trip Pro

(contralateral motor weakness, aphasia, loss of consciousness, or seizures) occurred, regardless of SP or EEG changes.Shunt placement was necessary because of neurologic changes in 10% (32/314) of all CEAs performed under CBA. Only 3 patients (1.4%) of 216 required shunt placement if SP was 50 mm Hg or more, vs 29 (29.6%) of 98 if SP was less than 50 mm Hg (P < .00001; sensitivity, 29.8%; specificity, 98.6%). In patients with SP of 40 mm Hg or more, 7 (2.6%) of 270 required shunt placement, vs 25 (56.8

2007 Journal of Vascular Surgery

3779. Recurrent late cerebral necrosis with aggressive characteristics after radiosurgical treatment of an arteriovenous malformation. Case report. (Abstract)

malformation (AVM) treated with linear accelerator radiosurgery 13 years before presentation and complicated by radiation necrosis 11 years before presentation, exhibited new-onset mixed aphasia, right hemiparesis, and right hemineglect. Imaging studies demonstrated hemorrhage and an enlarging, heterogeneously enhancing mass in the region of the previously treated AVM. The patient was treated medically with corticosteroid agents, and stabilized temporarily. Unfortunately, his condition worsened

2006 Journal of Neurosurgery

3780. Gamma Knife surgery targeting the centromedian nucleus of the thalamus for the palliative management of thalamic pain: durable response in stroke-induced thalamic pain syndrome. (Abstract)

the thalamus, suffered a right hemiplegia and expressive aphasia. One year poststroke, severe right-sided facial, scalp, arm, and trunk pain developed and was exacerbated by any tactile contact. Medical treatment had failed. Medical illness, including mandatory anticoagulation therapy for atrial fibrillation, precluded surgical procedures. Minimally invasive radiosurgery was offered as an alternative. Magnetic resonance imaging and computed tomography were used to localize the left CMN. A single shot

2006 Journal of Neurosurgery

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