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3641. Stroke: a randomized trial of exercise or relaxation. (Abstract)

Stroke: a randomized trial of exercise or relaxation. To determine the feasibility and effect of exercise training after stroke.Randomized exploratory trial comparing exercise training (including progressive endurance and resistance training) with relaxation (attention control).Interventions were performed in a rehabilitation hospital.Sixty-six independently ambulatory patients (mean age 72, 36 men) without significant dysphasia, confusion, or medical contraindications to exercise training who

2007 Journal of the American Geriatrics Society Controlled trial quality: uncertain

3642. Neural correlates of Dutch Verb Second in speech production. (Abstract)

Neural correlates of Dutch Verb Second in speech production. Dutch speakers with agrammatic Broca's aphasia are known to have problems with the production of finite verbs in main clauses. This performance pattern has been accounted for in terms of the specific syntactic complexity of the Dutch main clause structure, which requires an extra syntactic operation (Verb Second), relative to the basic Subject-Object-Verb order surfacing in Dutch subordinate clauses. We report an fMRI study

2008 Brain and language

3643. The effect of topical application of pure honey on radiation-induced mucositis: a randomized clinical trial. (Abstract)

The effect of topical application of pure honey on radiation-induced mucositis: a randomized clinical trial. Radiation-induced mucositis is an early effect of head and neck radiotherapy. Mucositis can cause ulcers, and patients may experience pain and dysphasia which need treatment. The aim of this study is to evaluate the effect of pure natural honey on radiation induced mucositis.In this randomized single blind (examiner blind) clinical trial 40 patients with head and neck cancer requiring

2008 The journal of contemporary dental practice Controlled trial quality: uncertain

3644. Intraoperative subcortical stimulation mapping of language pathways in a consecutive series of 115 patients with Grade II glioma in the left dominant hemisphere. (Abstract)

paraphasia when stimulated; 2) inferior frontooccipital fasciculus, generating semantic paraphasia when stimulated; 3) subcallosal fasciculus, inducing transcortical motor aphasia during stimulation; 4) frontoparietal phonological loop, eliciting speech apraxia during stimulation; and 5) fibers coming from the ventral premotor cortex, inducing anarthria when stimulated. These structures were preserved, representing the limits of the resection. Despite a transient immediate postoperative worsening, all

2008 Journal of Neurosurgery

3645. Intraoperative mapping of language functions: a longitudinal neurolinguistic analysis. Full Text available with Trip Pro

, including cases both with and without preoperative disturbances. Risk factors for postoperative aphasic disturbance were preoperative aphasia (p<0.0002), intraoperative complications (p<0.02), language-positive sites within the tumor (p<0.001), and nonfrontal lesion location (p<0.001). In patients without a preoperative deficit, a normal (yet submaximal) naming performance was a powerful predictor for an early postoperative aphasic disturbance (p<0.0003). Seven months after treatment 10.9% of the 128 (...) cases without preoperative aphasic disturbances continued to demonstrate new postoperative language disturbances. A total of 17.6% of all cases demonstrated new postoperative language disturbances after 7 months. Risk factors for persistent aphasic disturbance were increased age (>40 years, p<0.02) and preoperative aphasia (p<0.001).Every attempt should be undertaken to preserve language-relevant areas intraoperatively, even when they are located within the tumor. New postoperative deficits resolve

2008 Journal of Neurosurgery

3646. Mesenteric pseudoaneurysm and cerebral stroke as sequelae of infective endocarditis in an adolescent. (Abstract)

and eventual cardiac murmur and was found to have vancomycin-resistant Enterococcus growing as a vegetation on a previously undiagnosed bicuspid aortic valve. He had a cerebral stroke presenting as Broca's aphasia before cardiac surgery, as well as a superior mesenteric artery pseudoaneurysm several days postoperatively. The case highlights some of the serious surgical complications that can occur in young persons with infective endocarditis, as well as many of the problems involved in managing a patient

2008 Journal of Pediatric Surgery

3647. Arcuate fasciculus tractography integrated into Gamma Knife surgery. Full Text available with Trip Pro

malformations adjacent to the AF. Diffusion tensor images were acquired before the frame was affixed to the patient's head and DT tractography images of the AF were created using the authors' original software. The data from DT tractography and stereotactic 3D imaging studies obtained after frame fixation were transported to a treatment planning workstation for GKS and coregistered so that the delivered doses and incidence of posttreatment aphasia could be assessed.The AF could not be depicted in 2 patients (...) who initially presented with motor aphasia caused by hemorrhaging from arteriovenous malformations. During the median follow-up period of 29 months after GKS, aphasia developed in 2 patients: 30 Gy delivered to the frontal portion of the AF caused conduction aphasia in 1 patient, and 9.6 Gy to the temporal portion led to motor aphasia in the other. Speech dysfunction was not observed after a maximum radiation dose of 10.0-16.8 Gy was delivered to the frontal fibers in 4 patients, and 3.6-5.2 Gy

2008 Journal of Neurosurgery

3648. Treatment of a middle cerebral artery giant aneurysm using a covered stent. Case report. (Abstract)

Treatment of a middle cerebral artery giant aneurysm using a covered stent. Case report. The authors report the case of a 60-year-old man harboring a wide-necked giant aneurysm of the M1 segment of the left middle cerebral artery (MCA); his symptoms included transient ischemic attacks characterized by right hemiparesis and aphasia. The aneurysm was treated by placing a covered stent across the orifice of the aneurysm. The 18-month follow-up examination showed a very good outcome, with perfect (...) left MCA patency, no new ischemic lesion, and minor residual aphasia and right hemiparesis. This is the first report in the literature of an MCA aneurysm treated using a covered stent.

2006 Journal of Neurosurgery

3649. Correlation of carotid artery stump pressure and neurologic changes during 474 carotid endarterectomies performed in awake patients. Full Text available with Trip Pro

baseline. Accurate SPs were confirmed by the finding of flatline waveforms after internal carotid artery clamping. Selective shunting was performed when neurologic changes occurred (aphasia, inability to squeeze the contralateral hand, decreased consciousness), regardless of SP. During this same period, 142 patients underwent CEA using GA, and SP was also measured.Shunting was necessary because of neurologic changes in 7.2% (34/474) of all CEAs performed using CBA: 0.9% (3/335) with SPs > or = 50 mm Hg

2005 Journal of Vascular Surgery

3650. Prospective evaluation of electroencephalography, carotid artery stump pressure, and neurologic changes during 314 consecutive carotid endarterectomies performed in awake patients. Full Text available with Trip Pro

(contralateral motor weakness, aphasia, loss of consciousness, or seizures) occurred, regardless of SP or EEG changes.Shunt placement was necessary because of neurologic changes in 10% (32/314) of all CEAs performed under CBA. Only 3 patients (1.4%) of 216 required shunt placement if SP was 50 mm Hg or more, vs 29 (29.6%) of 98 if SP was less than 50 mm Hg (P < .00001; sensitivity, 29.8%; specificity, 98.6%). In patients with SP of 40 mm Hg or more, 7 (2.6%) of 270 required shunt placement, vs 25 (56.8

2007 Journal of Vascular Surgery

3651. Recurrent late cerebral necrosis with aggressive characteristics after radiosurgical treatment of an arteriovenous malformation. Case report. (Abstract)

malformation (AVM) treated with linear accelerator radiosurgery 13 years before presentation and complicated by radiation necrosis 11 years before presentation, exhibited new-onset mixed aphasia, right hemiparesis, and right hemineglect. Imaging studies demonstrated hemorrhage and an enlarging, heterogeneously enhancing mass in the region of the previously treated AVM. The patient was treated medically with corticosteroid agents, and stabilized temporarily. Unfortunately, his condition worsened

2006 Journal of Neurosurgery

3652. Gamma Knife surgery targeting the centromedian nucleus of the thalamus for the palliative management of thalamic pain: durable response in stroke-induced thalamic pain syndrome. (Abstract)

the thalamus, suffered a right hemiplegia and expressive aphasia. One year poststroke, severe right-sided facial, scalp, arm, and trunk pain developed and was exacerbated by any tactile contact. Medical treatment had failed. Medical illness, including mandatory anticoagulation therapy for atrial fibrillation, precluded surgical procedures. Minimally invasive radiosurgery was offered as an alternative. Magnetic resonance imaging and computed tomography were used to localize the left CMN. A single shot

2006 Journal of Neurosurgery

3653. Long-term follow-up of meningiomas of the cavernous sinus after surgical treatment alone. Full Text available with Trip Pro

surgery was performed via a presigmoid-retrolabyrinthine or retrosigmoid approach in 13 and 14 patients, respectively.The mortality rate was 5% and two patients had severe hemiplegic or aphasic sequelae. The creation or aggravation of disorders in vision, ocular motility, or trigeminal function occurred in 19, 29, and 24% of patients respectively, with a significantly higher rate of complications when resection was performed inside the CS (p < 0.05). Gross-total removal of both the extra

2007 Journal of Neurosurgery

3654. Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients. 1989. (Abstract)

, and for those with lesions acquired in early life or adulthood. These findings indicate a need for revision of the classical model of language localization. The combination of discrete localization in individual patients but substantial individual variability between patients also has major clinical implications for cortical resections of the dominant hemisphere, for it means that language cannot be reliably localized on anatomic criteria alone. A maximal resection with minimal risk of postoperative aphasia

2008 Journal of Neurosurgery

3655. Migraine aura or transient ischemic attacks? A five-year follow-up case-control study of women with transient central nervous system disorders in pregnancy. Full Text available with Trip Pro

during the five-year follow-up.The diagnosis of migraine aura was difficult because for many patients it was their first ever attack and headache tended to be absent or of non-migraineous type. The aura features were more complex, with several aura symptoms and a higher prevalence of sensory and dysphasic aura than usual. Gradually developing aura symptoms, or different aura symptoms occurring in succession as described in the International Classification of Headache Disorders, seem to be useful

2007 BMC Medicine

3656. Incidence of hemorrhage associated with electrophysiological studies performed using macroelectrodes and microelectrodes in functional neurosurgery. (Abstract)

of hemorrhage. Nineteen patients with arterial hypertension underwent 28 surgical procedures. Five cases of hemorrhage (2.02%) occurred. One patient presented with hemiparesis and dysphasia but no surgery was required. The incidence of hemorrhage in patients in whom MER was performed was 2.9%, whereas the incidence in patients in whom MER was not used was 1.4% (p = 0.6529). Bleeding occurred in 10.71% of patients with hypertension and 0.91% of those who were nonhypertensive (p = 0.0111). Among the 104

2005 Journal of Neurosurgery

3657. Hashimoto's encephalopathy mimicking migraine with aura. (Abstract)

Hashimoto's encephalopathy mimicking migraine with aura. We describe a patient with Hashimoto's encephalopathy presenting as long-standing episodes of aphasia associated with migraine-like headache. Repeated thyroid hormone levels were within normal values, but high titers of antithyroid antibodies in serum, and diffuse EEG slowing and CSF abnormalities during one episode led to the diagnosis.

2007 Headache

3658. Cluster-like headache aura status. (Abstract)

Cluster-like headache aura status. We describe a patient with successive attacks (40 to 90 minutes) of cluster-like headache associated with aphasia, and contralateral hemihypesthesia and hemiplegia. The condition can best be described as cluster-like headache aura status.

2005 Headache

3659. [Effects of three-stage rehabilitation treatment on acute cerebrovascular diseases: a prospective, randomized, controlled, multicenter study]. (Abstract)

, Barthel index, SF-36 scale, Lowenstein occupational therapy cognitive assessment (LOTCA), Westen aphasia battery, Hamilton depression scale, and modified Ashworth spasm scale, one week after the onset and by the ends of 1, 2, 3, 4, 5, and 6 months after the onset respectively.The scores of clinical neurological impairment, Fugl-Meyer scores, SF-36 scores, incidence of PSD, and modified Ashworth scores (for upper and lower limbs) were lower, and LOTCA scores and Barthel indexes were higher at different

2004 Zhonghua yi xue za zhi Controlled trial quality: uncertain

3660. Verbal mediation and memory for novel figural designs: a dual interference study. (Abstract)

Verbal mediation and memory for novel figural designs: a dual interference study. To the extent that all types of visual stimuli can be verbalized to some degree, verbal mediation is intrinsic in so-called "visual" memory processing. This impurity complicates the interpretation of visual memory performance, particularly in certain neurologically impaired populations (e.g., aphasia). The purpose of this study was to investigate the relative contributions of verbal mediation to recognition memory

2005 Brain and cognition Controlled trial quality: uncertain

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