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Aphasia

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1. Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke. Full Text available with Trip Pro

Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke. Stroke is one of the leading causes of disability worldwide and aphasia among survivors is common. Current speech and language therapy (SLT) strategies have only limited effectiveness in improving aphasia. A possible adjunct to SLT for improving SLT outcomes might be non-invasive brain stimulation by transcranial direct current stimulation (tDCS) to modulate cortical excitability and hence (...) to improve aphasia.To assess the effects of tDCS for improving aphasia in people who have had a stroke.We searched the Cochrane Stroke Group Trials Register (June 2018), CENTRAL (Cochrane Library, June 2018), MEDLINE (1948 to June 2018), Embase (1980 to June 2018), CINAHL (1982 to June 2018), AMED (1985 to June 2018), Science Citation Index (1899 to June 2018), and seven additional databases. We also searched trial registers and reference lists, handsearched conference proceedings and contacted authors

2019 Cochrane

2. Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia: the Big CACTUS three-arm RCT Full Text available with Trip Pro

Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia: the Big CACTUS three-arm RCT Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia: the Big CACTUS three-arm RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found

2020 NIHR HTA programme

3. Assessment of aphasia

in the brain. However, because fluency is a multi-dimensional term based on factors that can dissociate (grammatical accuracy, rate of speech, prosody, effort, articulatory precision, hesitations), it is often difficult to judge. A patient can be fluent on one dimension and non-fluent on another. Therefore, there is often disagreement between two people in judging fluency of an aphasic individual. Fluent aphasias are typically due to lesions posterior to the central sulcus: Wernicke aphasia with fluent (...) /17431404?tool=bestpractice.com Saur D, Kreher BW, Schnell S, et al. Ventral and dorsal pathways for language. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18035-40. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584675/ http://www.ncbi.nlm.nih.gov/pubmed/19004769?tool=bestpractice.com Follow-up treatment After identifying and treating the underlying cause of aphasia, such as acute stroke or herpes encephalitis, patients may have a residual aphasia. Such aphasic individuals benefit from referral

2018 BMJ Best Practice

4. Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia. Full Text available with Trip Pro

Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia. Language impairments caused by stroke (post-stroke aphasia, PSA) and neurodegeneration (primary progressive aphasia, PPA) have overlapping symptomatology, nomenclature and are classically divided into categorical subtypes. Surprisingly, PPA and PSA have rarely been directly compared in detail. Rather, previous studies have compared certain subtypes (e.g. semantic variants) or have (...) be a better conceptualization of aphasia from both causes; and (ii) despite the very different types of pathology, these broad classes of aphasia have considerable features in common.© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain.

2020 Brain

6. Efficacy of spoken word comprehension therapy in patients with chronic aphasia: a cross-over randomised controlled trial with structural imaging Full Text available with Trip Pro

Efficacy of spoken word comprehension therapy in patients with chronic aphasia: a cross-over randomised controlled trial with structural imaging Efficacy of spoken word comprehension therapy in patients with chronic aphasia: a cross-over randomised controlled trial with structural imaging - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily (...) 5;jnnp-2020-324256. doi: 10.1136/jnnp-2020-324256. Online ahead of print. Efficacy of spoken word comprehension therapy in patients with chronic aphasia: a cross-over randomised controlled trial with structural imaging # , # , , , , , , , , , , , , , Affiliations Expand Affiliations 1 UCL Queen Square Institute of Neurology, University College London, London, UK victoria.fleming@ucl.ac.uk. 2 School of Health and Rehabilitation Sciences, The University of Queensland, Saint Lucia, Queensland

2021 EvidenceUpdates

7. Neuroplasticity in post-stroke aphasia: A systematic review and meta-analysis of functional imaging studies of reorganization of language processing Full Text available with Trip Pro

Neuroplasticity in post-stroke aphasia: A systematic review and meta-analysis of functional imaging studies of reorganization of language processing Neuroplasticity in Post-Stroke Aphasia: A Systematic Review and Meta-Analysis of Functional Imaging Studies of Reorganization of Language Processing | Neurobiology of Language | MIT Press Journals Create a new account Email Can't sign in? Forgot your password? Enter your email address below and we will send you the reset instructions Email (...) Quick Email Links To submit proposals to either launch new journals or bring an existing journal to MIT Press, please contact Director for Journals and Open Access, Nick Lindsay at To submit an article please follow the submission guidelines for the appropriate journal(s). > > > > Neuroplasticity in Post-Stroke Aphasia: A Systematic Review and Meta-Analysis of Functional Imaging Studies of Reorganization of Language Processing Article navigation More About Neurobiology of Language Journal Resources

2020 Neurobiology of Language

8. Computerised speech and language therapy can help people with aphasia find words following a stroke. (Abstract)

Computerised speech and language therapy can help people with aphasia find words following a stroke. The studyPalmer R, Dimairo M, Cooper C, et al. Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS): a multicentre, single-blinded, randomised controlled trial. Lancet Neurol 2019;18:821-33.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/21/01

2020 BMJ

9. Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines

Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines | CADTH.ca Find the information you need Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines Published on: April 4, 2016 Project Number: RB0977-000 (...) , dysphagia, dysphasia, swallowing, water, water intake, Diagnostic, Yale, bedside, oropharyngeal Files Rapid Response Summary of Abstracts Published : April 4, 2016 Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter:

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

10. The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study Full Text available with Trip Pro

The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study Primary progressive aphasia is a language-led dementia, often associated with frontotemporal dementia. It presents as insidious deterioration of language skills (e.g. naming objects and understanding complex sentences), with relative sparing of cognitive skills initially. There is little research examining (...) the effectiveness of communication skills training for primary progressive aphasia, yet speech and language therapists (SLTs) report regularly using this in clinical practice. 'Better Conversations with Primary Progressive Aphasia' has potential to reduce barriers and increase facilitators to conversation and consequently improve confidence in communication and quality of life for people living with primary progressive aphasia and their conversation partners. The aim of this pilot study is to examine

2018 Pilot and feasibility studies Controlled trial quality: predicted high

11. Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. Full Text available with Trip Pro

Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients.The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological

2018 Dementia and Geriatric Cognitive Disorders

12. Speech therapy for treatment of adults with primary progressive aphasia

Speech therapy for treatment of adults with primary progressive aphasia Speech therapy for treatment of adults with primary progressive aphasia Speech therapy for treatment of adults with primary progressive aphasia HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Speech therapy for treatment of adults with primary progressive aphasia (...) . Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2016 Authors' conclusions Description of Technology: Speech therapy is effective for patients with acquired aphasia (e.g., after a stroke). Speech therapy in patients with primary progressive aphasia (PPA) and other forms of aphasia should be tailored to the needs of the patient, the caregiver, and the progression of the patient's underlying disease. Speech therapy is necessarily subjective, and the selection of activities during therapy

2016 Health Technology Assessment (HTA) Database.

13. Effects of multimodal communication program on patients with chronic aphasia: a single-subject A-B-A design study Full Text available with Trip Pro

Effects of multimodal communication program on patients with chronic aphasia: a single-subject A-B-A design study Aphasia as a common consequence of stroke, is an acquired neurologic communication disorder that can affect symbol language processing. Different types of intervention approaches have been introduced. Multimodal Communication Program (MCP) is a new augmentative alternative communication approach in chronic aphasia. The aim of this study was to investigate the effect of MCP (...) on communication skills of patients with chronic aphasia.This prospective, single subject, A-B-A design study was done during 2016 in Semnan, Iran. Participants were two patients with severe aphasia with a single left-hemisphere stroke. Three phases, including baseline, intervention and follow-up were administered. The patients received nine-hour intervention, over 10 working days.Three different scores were calculated for each patient: verbal efforts, the frequency of each modality and the accuracy

2018 Electronic physician Controlled trial quality: uncertain

14. ‘I felt pain. Deep pain…’: Experiences of primary caregivers of stroke survivors with aphasia in a South African township Full Text available with Trip Pro

‘I felt pain. Deep pain…’: Experiences of primary caregivers of stroke survivors with aphasia in a South African township Aphasia is an acquired impairment in language and in the cognitive processes that underlie language. Aphasia affects the quality of life of the person with aphasia (PWA) and his or her families in various ways in diverse contexts and cultures. It is therefore important that speech language therapists understand how different contextual and cultural factors may mediate (...) were analysed according to the principles of thematic analysis.Findings indicated that caregivers are unfamiliar with aphasia and the support available to them. Participants experienced frustration and found communication to be challenging owing to their lack of communication strategies. The participants' experiences reflected their context-specific experiences, such as feminisation of caregiving, barriers to healthcare, the influence of low health literacy and contextual perspectives on stroke

2018 African journal of disability

15. Types of Neuroplasticity and Factors Affecting Language Recovery in Patients with Aphasia: A Systematic Review Full Text available with Trip Pro

, Lincoln NB. Spontaneous recovery of language in patients with aphasia between 4 and 34 weeks after stroke. J Neurol Neurosurg Psychiatry . 1985; 48 (8):743-8. [PubMed: ]. [PubMed Central: ]. 20. Kertesz A, McCabe P. Recovery Patterns and Prognosis in Aphasia. Brain . 1977; 100 (1):1-18. doi: . 21. Borod JC, Carper JM, Naeser M. Long-term language recovery in left-handed aphasic patients. Aphasiology . 1990; 4 (6):561-72. doi: . 22. Basso A. Aphasia in left-handers *1Comparison of aphasia profiles (...) Types of Neuroplasticity and Factors Affecting Language Recovery in Patients with Aphasia: A Systematic Review Types of Neuroplasticity and Factors Affecting Language Recovery in Patients with Aphasia: A Systematic Review | Archives of Neuroscience | Full Text ARTICLE AUTHORS ARTICLE INFO Archives of Neuroscience Approved by the Scientific and Research Publications, IR Iran Articles About Journal , Ehsan Hemmati , Leila Ghasisin , 1 Student Research Committee, Isfahan University of Medical

2018 Archives of neuroscience

16. Gender differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query Full Text available with Trip Pro

Gender differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query Sex differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query | bioRxiv Search for this keyword New Results Sex differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query Mikkel Wallentin doi: https://doi.org/10.1101/407296 Mikkel Wallentin 1 Department of Linguistics, Cognitive Science and Semiotics, Aarhus University (...) , Jens Chr. Skous Vej 2, 8000 Aarhus C, Denmark 2 Center of Functionally Integrative Neuroscience, Aarhus University Hospital , Denmark 3 Interacting Minds Centre, Aarhus University , Denmark For correspondence: Abstract Background Studies have suggested that aphasia rates are different in men and women following stroke. One hypothesis says that men have more lateralized language function than women. Given unilateral stroke, this would lead to a prediction of men having higher aphasia rates than

2018 Cold Spring Harbor Laboratory

18. Structural white matter connectometry of word production in aphasia: an observational study. Full Text available with Trip Pro

Structural white matter connectometry of word production in aphasia: an observational study. While current dual-steam neurocognitive models of language function have coalesced around the view that distinct neuroanatomical networks subserve semantic and phonological processing, respectively, the specific white matter components of these networks remain a matter of debate. To inform this debate, we investigated relationships between structural white matter connectivity and word production (...) in a cross-sectional study of 42 participants with aphasia due to unilateral left hemisphere stroke. Specifically, we reconstructed a local connectome matrix for each participant from diffusion spectrum imaging data and regressed these matrices on indices of semantic and phonological ability derived from their responses to a picture-naming test and a computational model of word production. These connectometry analyses indicated that both dorsally located (arcuate fasciculus) and ventrally located

2020 Brain

19. Taking the sublexical route: brain dynamics of reading in the semantic variant of primary progressive aphasia. Full Text available with Trip Pro

Taking the sublexical route: brain dynamics of reading in the semantic variant of primary progressive aphasia. Reading aloud requires mapping an orthographic form to a phonological one. The mapping process relies on sublexical statistical regularities (e.g. 'oo' to |uː|) or on learned lexical associations between a specific visual form and a series of sounds (e.g. yacht to/jɑt/). Computational, neuroimaging, and neuropsychological evidence suggest that sublexical, phonological and lexico (...) -semantic processes rely on partially distinct neural substrates: a dorsal (occipito-parietal) and a ventral (occipito-temporal) route, respectively. Here, we investigated the spatiotemporal features of orthography-to-phonology mapping, capitalizing on the time resolution of magnetoencephalography and the unique clinical model offered by patients with semantic variant of primary progressive aphasia (svPPA). Behaviourally, patients with svPPA manifest marked lexico-semantic impairments including

2020 Brain

20. Value of Vascular and Non-Vascular Pattern on Computed Tomography Perfusion in Patients With Acute Isolated Aphasia. (Abstract)

Value of Vascular and Non-Vascular Pattern on Computed Tomography Perfusion in Patients With Acute Isolated Aphasia. Acute onset aphasia may be due to stroke but also to other causes, which are commonly referred to as stroke mimics. We hypothesized that, in patients with acute isolated aphasia, distinct brain perfusion patterns are related to the cause and the clinical outcome. Herein, we analyzed the prognostic yield and the diagnostic usefulness of computed tomography perfusion (CTP (...) ) in patients with acute isolated aphasia.From a single-center registry, we selected a cohort of 154 patients presenting with acute isolated aphasia who had a whole-brain CTP study available. We collected the main clinical and radiological data. We categorized brain perfusion studies on CTP into vascular and nonvascular perfusion patterns and the cause of aphasia as ischemic stroke, transient ischemic attack, stroke mimic, and undetermined cause. The primary clinical outcome was the persistence of aphasia

2020 Stroke

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