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Aphasia

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1. Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke. (Abstract)

Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke. Stroke is one of the leading causes of disability worldwide and aphasia among survivors is common. Current speech and language therapy (SLT) strategies have only limited effectiveness in improving aphasia. A possible adjunct to SLT for improving SLT outcomes might be non-invasive brain stimulation by transcranial direct current stimulation (tDCS) to modulate cortical excitability and hence (...) to improve aphasia.To assess the effects of tDCS for improving aphasia in people who have had a stroke.We searched the Cochrane Stroke Group Trials Register (June 2018), CENTRAL (Cochrane Library, June 2018), MEDLINE (1948 to June 2018), Embase (1980 to June 2018), CINAHL (1982 to June 2018), AMED (1985 to June 2018), Science Citation Index (1899 to June 2018), and seven additional databases. We also searched trial registers and reference lists, handsearched conference proceedings and contacted authors

2019 Cochrane

2. Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia: the Big CACTUS three-arm RCT Full Text available with Trip Pro

Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia: the Big CACTUS three-arm RCT Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia: the Big CACTUS three-arm RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found

2020 NIHR HTA programme

3. Assessment of aphasia

in the brain. However, because fluency is a multi-dimensional term based on factors that can dissociate (grammatical accuracy, rate of speech, prosody, effort, articulatory precision, hesitations), it is often difficult to judge. A patient can be fluent on one dimension and non-fluent on another. Therefore, there is often disagreement between two people in judging fluency of an aphasic individual. Fluent aphasias are typically due to lesions posterior to the central sulcus: Wernicke aphasia with fluent (...) /17431404?tool=bestpractice.com Saur D, Kreher BW, Schnell S, et al. Ventral and dorsal pathways for language. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18035-40. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584675/ http://www.ncbi.nlm.nih.gov/pubmed/19004769?tool=bestpractice.com Follow-up treatment After identifying and treating the underlying cause of aphasia, such as acute stroke or herpes encephalitis, patients may have a residual aphasia. Such aphasic individuals benefit from referral

2018 BMJ Best Practice

4. Computerised speech and language therapy can help people with aphasia find words following a stroke. (Abstract)

Computerised speech and language therapy can help people with aphasia find words following a stroke. The studyPalmer R, Dimairo M, Cooper C, et al. Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS): a multicentre, single-blinded, randomised controlled trial. Lancet Neurol 2019;18:821-33.This project was funded by the NIHR Health Technology Assessment Programme (project number 12/21/01

2020 BMJ

5. The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study Full Text available with Trip Pro

The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study Primary progressive aphasia is a language-led dementia, often associated with frontotemporal dementia. It presents as insidious deterioration of language skills (e.g. naming objects and understanding complex sentences), with relative sparing of cognitive skills initially. There is little research examining (...) the effectiveness of communication skills training for primary progressive aphasia, yet speech and language therapists (SLTs) report regularly using this in clinical practice. 'Better Conversations with Primary Progressive Aphasia' has potential to reduce barriers and increase facilitators to conversation and consequently improve confidence in communication and quality of life for people living with primary progressive aphasia and their conversation partners. The aim of this pilot study is to examine

2018 Pilot and feasibility studies Controlled trial quality: predicted high

6. Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. Full Text available with Trip Pro

Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients.The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological

2018 Dementia and Geriatric Cognitive Disorders

7. What do people with aphasia want to be able to say? A content analysis of words identified as personally relevant by people with aphasia. Full Text available with Trip Pro

What do people with aphasia want to be able to say? A content analysis of words identified as personally relevant by people with aphasia. Word finding is a common difficulty for people with aphasia. Targeting words that are relevant to the individual could maximise the usefulness and impact of word finding therapy.To provide insights into words that people with aphasia perceive to be personally relevant.100 people with aphasia were each asked to identify 100 words that would be particularly (...) or specialist words for which material needs to be individually prepared. However there is some commonality in the words chosen by people with aphasia. This could inform pre-prepared materials for use in word finding therapy from which personally relevant words could be selected for practice.

2017 PLoS ONE

8. Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines

Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines | CADTH.ca Find the information you need Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines Three-Ounce Water Swallow Challenge for Oropharyngeal Dysphasia: Diagnostic Accuracy and Guidelines Published on: April 4, 2016 Project Number: RB0977-000 (...) , dysphagia, dysphasia, swallowing, water, water intake, Diagnostic, Yale, bedside, oropharyngeal Files Rapid Response Summary of Abstracts Published : April 4, 2016 Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter:

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

9. Effects of multimodal communication program on patients with chronic aphasia: a single-subject A-B-A design study Full Text available with Trip Pro

Effects of multimodal communication program on patients with chronic aphasia: a single-subject A-B-A design study Aphasia as a common consequence of stroke, is an acquired neurologic communication disorder that can affect symbol language processing. Different types of intervention approaches have been introduced. Multimodal Communication Program (MCP) is a new augmentative alternative communication approach in chronic aphasia. The aim of this study was to investigate the effect of MCP (...) on communication skills of patients with chronic aphasia.This prospective, single subject, A-B-A design study was done during 2016 in Semnan, Iran. Participants were two patients with severe aphasia with a single left-hemisphere stroke. Three phases, including baseline, intervention and follow-up were administered. The patients received nine-hour intervention, over 10 working days.Three different scores were calculated for each patient: verbal efforts, the frequency of each modality and the accuracy

2018 Electronic physician Controlled trial quality: uncertain

10. ‘I felt pain. Deep pain…’: Experiences of primary caregivers of stroke survivors with aphasia in a South African township Full Text available with Trip Pro

‘I felt pain. Deep pain…’: Experiences of primary caregivers of stroke survivors with aphasia in a South African township Aphasia is an acquired impairment in language and in the cognitive processes that underlie language. Aphasia affects the quality of life of the person with aphasia (PWA) and his or her families in various ways in diverse contexts and cultures. It is therefore important that speech language therapists understand how different contextual and cultural factors may mediate (...) were analysed according to the principles of thematic analysis.Findings indicated that caregivers are unfamiliar with aphasia and the support available to them. Participants experienced frustration and found communication to be challenging owing to their lack of communication strategies. The participants' experiences reflected their context-specific experiences, such as feminisation of caregiving, barriers to healthcare, the influence of low health literacy and contextual perspectives on stroke

2018 African journal of disability

11. Efficacy of early cognitive-linguistic treatment for aphasia due to stroke: A randomised controlled trial (Rotterdam Aphasia Therapy Study-3) Full Text available with Trip Pro

Efficacy of early cognitive-linguistic treatment for aphasia due to stroke: A randomised controlled trial (Rotterdam Aphasia Therapy Study-3) One third of patients with acute stroke have aphasia. The majority receive speech and language therapy. There is evidence for a beneficial effect of speech and language therapy on restoring communication, but it is unknown whether and how efficacy of speech and language therapy is influenced by timing of treatment. We studied whether speech and language (...) therapy early after stroke by way of intensive cognitive-linguistic treatment is more effective than no speech and language therapy in the Rotterdam Aphasia Therapy Study-3, a multicentre randomised single-blind trial.Stroke patients with first-ever aphasia were randomised within 2 weeks of onset to either 4 weeks of early intensive cognitive-linguistic treatment (1 h/day) or no language treatment. Hereafter, both groups received regular speech and language therapy. Primary outcome was the score

2017 European Stroke Journal Controlled trial quality: predicted high

12. Discourse Characteristics in Aphasia Beyond the Western Aphasia Battery Cutoff Full Text available with Trip Pro

Discourse Characteristics in Aphasia Beyond the Western Aphasia Battery Cutoff This study examined discourse characteristics of individuals with aphasia who scored at or above the 93.8 cutoff on the Aphasia Quotient subtests of the Western Aphasia Battery-Revised (WAB-R; Kertesz, 2007). They were compared with participants without aphasia and those with anomic aphasia.Participants were from the AphasiaBank database and included 28 participants who were not aphasic by WAB-R score (NABW), 92 (...) participants with anomic aphasia, and 177 controls. Cinderella narratives were analyzed using the Computerized Language Analysis programs (MacWhinney, 2000). Outcome measures were words per minute, percent word errors, lexical diversity using the moving average type-token ratio (Covington, 2007b), main concept production, number of utterances, mean length of utterance, and proposition density.Results showed that the NABW group was significantly different from the controls on all measures except MLU

2017 American Journal of Speech-Language Pathology

13. Neuroimaging Correlates of Post-Stroke Aphasia Rehabilitation in a Pilot Randomized Trial of Constraint-Induced Aphasia Therapy Full Text available with Trip Pro

Neuroimaging Correlates of Post-Stroke Aphasia Rehabilitation in a Pilot Randomized Trial of Constraint-Induced Aphasia Therapy BACKGROUND Recovery from post-stroke aphasia is a long and complex process with an uncertain outcome. Various interventions have been proposed to augment the recovery, including constraint-induced aphasia therapy (CIAT). CIAT has been applied to patients suffering from post-stroke aphasia in several unblinded studies to show mild-to-moderate linguistic gains. The aim (...) of the present study was to evaluate the neuroimaging correlates of CIAT in patients with chronic aphasia related to left middle cerebral artery stroke. MATERIAL AND METHODS Out of 24 patients recruited in a pilot randomized blinded trial of CIAT, 19 patients received fMRI of language. Eleven of them received CIAT (trained) and eight served as a control group (untrained). Each patient participated in three fMRI sessions (before training, after training, and 3 months later) that included semantic decision

2017 Medical science monitor : international medical journal of experimental and clinical research Controlled trial quality: uncertain

14. Efficacy of intensive aphasia therapy in patients with chronic stroke: a randomised controlled trial Full Text available with Trip Pro

Efficacy of intensive aphasia therapy in patients with chronic stroke: a randomised controlled trial Recent evidence has fuelled the debate on the role of massed practice in the rehabilitation of chronic post-stroke aphasia. Here, we further determined the optimal daily dosage and total duration of intensive speech-language therapy.Individuals with chronic aphasia more than 1 year post-stroke received Intensive Language-Action Therapy in a randomised, parallel-group, blinded-assessment (...) , controlled trial. Participants were randomly assigned to one of two outpatient groups who engaged in either highly-intensive practice (Group I: 4 hours daily) or moderately-intensive practice (Group II: 2 hours daily). Both groups went through an initial waiting period and two successive training intervals. Each phase lasted 2 weeks. Co-primary endpoints were defined after each training interval.Thirty patients-15 per group-completed the study. A primary outcome measure (Aachen Aphasia Test) revealed

2018 EvidenceUpdates

15. Transcranial Direct Current Stimulation Does Not Improve Language Outcome in Subacute Poststroke Aphasia Full Text available with Trip Pro

Transcranial Direct Current Stimulation Does Not Improve Language Outcome in Subacute Poststroke Aphasia The aim of the present study is to investigate the effect of transcranial direct current stimulation on word-finding treatment outcome in subacute poststroke aphasia.In this multi-center, double-blind, randomized controlled trial with 6-month follow-up, we included 58 patients with subacute aphasia (<3 months poststroke), who were enrolled in a stroke rehabilitation program. Patients

2018 EvidenceUpdates

16. Effects of repetitive transcranial magnetic stimulation with different frequencies on post-stroke aphasia: A PRISMA-compliant meta-analysis. Full Text available with Trip Pro

Effects of repetitive transcranial magnetic stimulation with different frequencies on post-stroke aphasia: A PRISMA-compliant meta-analysis. Previous studies indicated inconsistent results for the treatment effect of repetitive transcranial magnetic stimulation (rTMS) on post-stroke aphasics. The study conducted a meta-analysis to evaluate whether the rTMS with different frequencies demonstrated any effect in patients with post-stroke aphasia.Electronic databases (PubMed, Web of Science (...) , Medline, EMBASE, and Google Scholar) were searched for articles published before July 2019. Statistical analyses were made using STATA 12.0 software. Standard mean difference (SMD) with 95% confidence intervals (CI) were calculated for the treatment effect of rTMS on post-stroke aphasia.Meta-analysis indicated significant treatment effects on naming of rTMS in post-stroke aphasics (SMD 0.76, 95%CI 0.16 to 1.36, I = 76.9%, P < .001). Subgroup analyses showed significant treatment effects on naming

2020 Medicine

17. Speech therapy for treatment of adults with primary progressive aphasia

Speech therapy for treatment of adults with primary progressive aphasia Speech therapy for treatment of adults with primary progressive aphasia Speech therapy for treatment of adults with primary progressive aphasia HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Speech therapy for treatment of adults with primary progressive aphasia (...) . Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2016 Authors' conclusions Description of Technology: Speech therapy is effective for patients with acquired aphasia (e.g., after a stroke). Speech therapy in patients with primary progressive aphasia (PPA) and other forms of aphasia should be tailored to the needs of the patient, the caregiver, and the progression of the patient's underlying disease. Speech therapy is necessarily subjective, and the selection of activities during therapy

2016 Health Technology Assessment (HTA) Database.

18. Combined Dextroamphetamine and Transcranial Direct Current Stimulation in Poststroke Aphasia. (Abstract)

Combined Dextroamphetamine and Transcranial Direct Current Stimulation in Poststroke Aphasia. There is a growing need for various effective adjunctive treatment options for speech recovery after stroke. A pharmacological agent combined with noninvasive brain stimulation has not been previously reported for poststroke aphasia recovery. In this "proof of concept" study, we aimed to test the safety of a combined intervention consisting of dextroamphetamine, transcranial direct current stimulation (...) , and speech and language therapy in subjects with nonfluent aphasia. Ten subjects with chronic nonfluent aphasia underwent two experiments where they received dextroamphetamine or placebo along with transcranial direct current stimulation and speech and language therapy on two separate days. The Western Aphasia Battery-Revised was used to monitor changes in speech performance. No serious adverse events were observed. There was no significant increase in blood pressure with amphetamine or deterioration

2017 American journal of physical medicine & rehabilitation Controlled trial quality: uncertain

19. The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature. Full Text available with Trip Pro

The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature. Akinetic mutism is a key diagnostic feature of prion diseases, however, their rapidly progressive nature makes detailed investigation of the language disorder in a large cohort extremely challenging. This study aims to position prion diseases in the nosology of language disorders and improve early clinical recognition.A systematic, prospective investigation of language (...) . Patients were also impaired on a test of dynamic aphasia.These results provide evidence that the language disorder in prion disease is rarely an isolated clinical or cognitive feature. The language abnormality is indicative of a dynamic aphasia in the context of a prominent dysexecutive syndrome, similar to that seen in patients with the degenerative movement disorder progressive supranuclear palsy (PSP).

2018 PLoS ONE

20. What speech and language therapy do community dwelling stroke survivors with aphasia receive in the UK? Full Text available with Trip Pro

What speech and language therapy do community dwelling stroke survivors with aphasia receive in the UK? Speech and language therapy provision for aphasia (a language disorder) post stroke has been studied over time through surveys completed by speech and language therapists. This paper revisits provision based on what was received by 278 patients in 21 UK speech and language therapy departments in 2014-2016.To explore the speech and language therapy received by community dwelling people (...) with post stroke aphasia in the UK.A quantitative content analysis was conducted by two speech and language therapist researchers. Therapy goals recorded were coded into categories and subcategories. Descriptive statistics were used to identify the frequency with which goal categories were targeted, average therapy time received, length and frequency of therapy sessions, personnel involved and mode of delivery.Forty-five percent of participants were in receipt of therapy in the three month window

2018 PLoS ONE Controlled trial quality: uncertain

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