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Aphasia

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1. Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke. (PubMed)

Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke. Stroke is one of the leading causes of disability worldwide and aphasia among survivors is common. Current speech and language therapy (SLT) strategies have only limited effectiveness in improving aphasia. A possible adjunct to SLT for improving SLT outcomes might be non-invasive brain stimulation by transcranial direct current stimulation (tDCS) to modulate cortical excitability and hence (...) to improve aphasia.To assess the effects of tDCS for improving aphasia in people who have had a stroke.We searched the Cochrane Stroke Group Trials Register (June 2018), CENTRAL (Cochrane Library, June 2018), MEDLINE (1948 to June 2018), Embase (1980 to June 2018), CINAHL (1982 to June 2018), AMED (1985 to June 2018), Science Citation Index (1899 to June 2018), and seven additional databases. We also searched trial registers and reference lists, handsearched conference proceedings and contacted authors

2019 Cochrane

2. Assessment of aphasia

Assessment of aphasia Assessment of aphasia - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of aphasia Last reviewed: February 2019 Last updated: July 2018 Summary Aphasia is an acquired impairment of language that affects comprehension and production of words, sentences, and/or discourse. It is typically characterised by errors in word retrieval or selection, including: Semantic paraphasias (substituting (...) . Definitions: aphasia, dysarthria, and apraxia It is important to distinguish aphasia from dysarthria or apraxia. Aphasia is a selective impairment of language or the cognitive processes that underlie language. Individuals with dementia often have language problems, but they also have at least equally severe deficits in episodic memory, visuospatial skills and/or executive functions (e.g., organisation, planning, decision making). Dysarthria is an acquired disorder of speech production due to weakness

2018 BMJ Best Practice

3. REhabilitation and recovery of peopLE with Aphasia after StrokE (RELEASE): utilizing secondary data to enhance speech and language therapy interventions for people with aphasia after stroke

REhabilitation and recovery of peopLE with Aphasia after StrokE (RELEASE): utilizing secondary data to enhance speech and language therapy interventions for people with aphasia after stroke Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites

2018 PROSPERO

4. The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study (PubMed)

The ‘Better Conversations with Primary Progressive Aphasia (BCPPA)’ program for people with PPA (Primary Progressive Aphasia): protocol for a randomised controlled pilot study Primary progressive aphasia is a language-led dementia, often associated with frontotemporal dementia. It presents as insidious deterioration of language skills (e.g. naming objects and understanding complex sentences), with relative sparing of cognitive skills initially. There is little research examining (...) the effectiveness of communication skills training for primary progressive aphasia, yet speech and language therapists (SLTs) report regularly using this in clinical practice. 'Better Conversations with Primary Progressive Aphasia' has potential to reduce barriers and increase facilitators to conversation and consequently improve confidence in communication and quality of life for people living with primary progressive aphasia and their conversation partners. The aim of this pilot study is to examine

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2018 Pilot and feasibility studies Controlled trial quality: predicted high

5. Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. (PubMed)

Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients.The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological

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2018 Dementia and Geriatric Cognitive Disorders

6. What do people with aphasia want to be able to say? A content analysis of words identified as personally relevant by people with aphasia. (PubMed)

What do people with aphasia want to be able to say? A content analysis of words identified as personally relevant by people with aphasia. Word finding is a common difficulty for people with aphasia. Targeting words that are relevant to the individual could maximise the usefulness and impact of word finding therapy.To provide insights into words that people with aphasia perceive to be personally relevant.100 people with aphasia were each asked to identify 100 words that would be particularly (...) or specialist words for which material needs to be individually prepared. However there is some commonality in the words chosen by people with aphasia. This could inform pre-prepared materials for use in word finding therapy from which personally relevant words could be selected for practice.

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2017 PLoS ONE

7. Speech and language therapy for aphasia following stroke. (PubMed)

Speech and language therapy for aphasia following stroke. Aphasia is an acquired language impairment following brain damage that affects some or all language modalities: expression and understanding of speech, reading, and writing. Approximately one third of people who have a stroke experience aphasia.To assess the effects of speech and language therapy (SLT) for aphasia following stroke.We searched the Cochrane Stroke Group Trials Register (last searched 9 September 2015), CENTRAL (2015, Issue (...) participants) assessed SLT with social support and stimulation; meta-analyses found no evidence of a difference in functional communication, but more participants withdrew from social support interventions than SLT. Thirty-eight randomised comparisons (1242 participants) assessed two approaches to SLT. Functional communication was significantly better in people with aphasia that received therapy at a high intensity, high dose, or over a long duration compared to those that received therapy at a lower

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2016 Cochrane

8. Perspectives of people with aphasia post-stroke towards recovery, living successfully with aphasia and related constructs: a systematic review and qualitative thematic synthesis

Perspectives of people with aphasia post-stroke towards recovery, living successfully with aphasia and related constructs: a systematic review and qualitative thematic synthesis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email

2017 PROSPERO

9. ‘I felt pain. Deep pain…’: Experiences of primary caregivers of stroke survivors with aphasia in a South African township (PubMed)

‘I felt pain. Deep pain…’: Experiences of primary caregivers of stroke survivors with aphasia in a South African township Aphasia is an acquired impairment in language and in the cognitive processes that underlie language. Aphasia affects the quality of life of the person with aphasia (PWA) and his or her families in various ways in diverse contexts and cultures. It is therefore important that speech language therapists understand how different contextual and cultural factors may mediate (...) were analysed according to the principles of thematic analysis.Findings indicated that caregivers are unfamiliar with aphasia and the support available to them. Participants experienced frustration and found communication to be challenging owing to their lack of communication strategies. The participants' experiences reflected their context-specific experiences, such as feminisation of caregiving, barriers to healthcare, the influence of low health literacy and contextual perspectives on stroke

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2018 African journal of disability

10. Effects of multimodal communication program on patients with chronic aphasia: a single-subject A-B-A design study (PubMed)

Effects of multimodal communication program on patients with chronic aphasia: a single-subject A-B-A design study Aphasia as a common consequence of stroke, is an acquired neurologic communication disorder that can affect symbol language processing. Different types of intervention approaches have been introduced. Multimodal Communication Program (MCP) is a new augmentative alternative communication approach in chronic aphasia. The aim of this study was to investigate the effect of MCP (...) on communication skills of patients with chronic aphasia.This prospective, single subject, A-B-A design study was done during 2016 in Semnan, Iran. Participants were two patients with severe aphasia with a single left-hemisphere stroke. Three phases, including baseline, intervention and follow-up were administered. The patients received nine-hour intervention, over 10 working days.Three different scores were calculated for each patient: verbal efforts, the frequency of each modality and the accuracy

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2018 Electronic physician Controlled trial quality: uncertain

11. Efficacy of early cognitive-linguistic treatment for aphasia due to stroke: A randomised controlled trial (Rotterdam Aphasia Therapy Study-3) (PubMed)

Efficacy of early cognitive-linguistic treatment for aphasia due to stroke: A randomised controlled trial (Rotterdam Aphasia Therapy Study-3) One third of patients with acute stroke have aphasia. The majority receive speech and language therapy. There is evidence for a beneficial effect of speech and language therapy on restoring communication, but it is unknown whether and how efficacy of speech and language therapy is influenced by timing of treatment. We studied whether speech and language (...) therapy early after stroke by way of intensive cognitive-linguistic treatment is more effective than no speech and language therapy in the Rotterdam Aphasia Therapy Study-3, a multicentre randomised single-blind trial.Stroke patients with first-ever aphasia were randomised within 2 weeks of onset to either 4 weeks of early intensive cognitive-linguistic treatment (1 h/day) or no language treatment. Hereafter, both groups received regular speech and language therapy. Primary outcome was the score

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2017 European Stroke Journal Controlled trial quality: predicted high

12. Neuroimaging Correlates of Post-Stroke Aphasia Rehabilitation in a Pilot Randomized Trial of Constraint-Induced Aphasia Therapy (PubMed)

Neuroimaging Correlates of Post-Stroke Aphasia Rehabilitation in a Pilot Randomized Trial of Constraint-Induced Aphasia Therapy BACKGROUND Recovery from post-stroke aphasia is a long and complex process with an uncertain outcome. Various interventions have been proposed to augment the recovery, including constraint-induced aphasia therapy (CIAT). CIAT has been applied to patients suffering from post-stroke aphasia in several unblinded studies to show mild-to-moderate linguistic gains. The aim (...) of the present study was to evaluate the neuroimaging correlates of CIAT in patients with chronic aphasia related to left middle cerebral artery stroke. MATERIAL AND METHODS Out of 24 patients recruited in a pilot randomized blinded trial of CIAT, 19 patients received fMRI of language. Eleven of them received CIAT (trained) and eight served as a control group (untrained). Each patient participated in three fMRI sessions (before training, after training, and 3 months later) that included semantic decision

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2017 Medical science monitor : international medical journal of experimental and clinical research Controlled trial quality: uncertain

13. Discourse Characteristics in Aphasia Beyond the Western Aphasia Battery Cutoff (PubMed)

Discourse Characteristics in Aphasia Beyond the Western Aphasia Battery Cutoff This study examined discourse characteristics of individuals with aphasia who scored at or above the 93.8 cutoff on the Aphasia Quotient subtests of the Western Aphasia Battery-Revised (WAB-R; Kertesz, 2007). They were compared with participants without aphasia and those with anomic aphasia.Participants were from the AphasiaBank database and included 28 participants who were not aphasic by WAB-R score (NABW), 92 (...) participants with anomic aphasia, and 177 controls. Cinderella narratives were analyzed using the Computerized Language Analysis programs (MacWhinney, 2000). Outcome measures were words per minute, percent word errors, lexical diversity using the moving average type-token ratio (Covington, 2007b), main concept production, number of utterances, mean length of utterance, and proposition density.Results showed that the NABW group was significantly different from the controls on all measures except MLU

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2017 American Journal of Speech-Language Pathology

14. Constraint-induced aphasia therapy in post-stroke aphasia rehabilitation: A systematic review and meta-analysis of randomized controlled trials. (PubMed)

Constraint-induced aphasia therapy in post-stroke aphasia rehabilitation: A systematic review and meta-analysis of randomized controlled trials. Constraint-induced aphasia therapy (CIAT) has been widely used in post-stroke aphasia rehabilitation. An increasing number of clinical controlled trials have investigated the efficacy of the CIAT for the post-stroke aphasia.To systematically review the randomized controlled trials (RCTs) concerning the effect of the CIAT in post-stroke patients (...) with aphasia, and to identify the useful components of CIAT in post-stroke aphasia rehabilitation.A computerized database search was performed through five databases (Pubmed, EMbase, Medline, ScienceDirect and Cochrane library). Cochrane handbook domains were used to evaluate the methodological quality of the included RCTs.Eight RCTs qualified in the inclusion criteria. Inconsistent results were found in comparing the CIAT with conventional therapies without any component from the CIAT based on the results

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2017 PloS one

15. Diagnosis of aphasia in stroke populations: A systematic review of language tests. (PubMed)

Diagnosis of aphasia in stroke populations: A systematic review of language tests. Accurate aphasia diagnosis is important in stroke care. A wide range of language tests are available and include informal assessments, tests developed by healthcare institutions and commercially published tests available for purchase in pre-packaged kits. The psychometrics of these tests are often reported online or within the purchased test manuals, not the peer-reviewed literature, therefore the diagnostic (...) capabilities of these measures have not been systematically evaluated. This review aimed to identify both commercial and non-commercial language tests and tests used in stroke care and to examine the diagnostic capabilities of all identified measures in diagnosing aphasia in stroke populations.Language tests were identified through a systematic search of 161 publisher databases, professional and resource websites and language tests reported to be used in stroke care. Two independent reviewers evaluated

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2018 PLoS ONE

16. Perspectives of people with aphasia post-stroke towards personal recovery and living successfully: A systematic review and thematic synthesis. (PubMed)

Perspectives of people with aphasia post-stroke towards personal recovery and living successfully: A systematic review and thematic synthesis. There is increased focus on supporting people with chronic conditions to live well via person-centred, integrated care. There is a growing body of qualitative literature examining the insider perspectives of people with post-stroke aphasia (PWA) on topics relating to personal recovery and living successfully (PR-LS). To date no synthesis has been (...) appraised using predetermined criteria. Inductive and iterative analysis generated 5 analytical themes about promoting PR-LS. Aphasia occurs in the context of a wider social network that provides valued support and social companionship and has its own need for formal support. PWA want to make a positive contribution to society. The participation of PWA is facilitated by enabling environments and opportunities. PWA benefit from access to a flexible, responsive, life-relevant range of services in the long

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2019 PLoS ONE

17. Attention control comparisons with SLT for people with aphasia following stroke: methodological concerns raised following a systematic review

Attention control comparisons with SLT for people with aphasia following stroke: methodological concerns raised following a systematic review Attention control comparisons in trials of stroke rehabilitation require care to minimize the risk of comparison choice bias. We compared the similarities and differences in SLT and social support control interventions for people with aphasia.Trial data from the 2016 Cochrane systematic review of SLT for aphasia after stroke Methods: Direct and indirect (...) difference in therapy interventions. Social support is an important adjunct to formal language rehabilitation. Therapists should continue to enable those close to the person with aphasia to provide tailored communication support, functional language stimulation and opportunities to apply rehabilitation gains. Systematic group differences in completion rates is a design-related risk of bias in outcomes observed.

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2018 EvidenceUpdates

18. Efficacy of intensive aphasia therapy in patients with chronic stroke: a randomised controlled trial

Efficacy of intensive aphasia therapy in patients with chronic stroke: a randomised controlled trial Recent evidence has fuelled the debate on the role of massed practice in the rehabilitation of chronic post-stroke aphasia. Here, we further determined the optimal daily dosage and total duration of intensive speech-language therapy.Individuals with chronic aphasia more than 1 year post-stroke received Intensive Language-Action Therapy in a randomised, parallel-group, blinded-assessment (...) , controlled trial. Participants were randomly assigned to one of two outpatient groups who engaged in either highly-intensive practice (Group I: 4 hours daily) or moderately-intensive practice (Group II: 2 hours daily). Both groups went through an initial waiting period and two successive training intervals. Each phase lasted 2 weeks. Co-primary endpoints were defined after each training interval.Thirty patients-15 per group-completed the study. A primary outcome measure (Aachen Aphasia Test) revealed

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2018 EvidenceUpdates

19. Transcranial Direct Current Stimulation Does Not Improve Language Outcome in Subacute Poststroke Aphasia

Transcranial Direct Current Stimulation Does Not Improve Language Outcome in Subacute Poststroke Aphasia The aim of the present study is to investigate the effect of transcranial direct current stimulation on word-finding treatment outcome in subacute poststroke aphasia.In this multi-center, double-blind, randomized controlled trial with 6-month follow-up, we included 58 patients with subacute aphasia (<3 months poststroke), who were enrolled in a stroke rehabilitation program. Patients

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2018 EvidenceUpdates

20. Speech therapy for treatment of adults with primary progressive aphasia

Speech therapy for treatment of adults with primary progressive aphasia Speech therapy for treatment of adults with primary progressive aphasia Speech therapy for treatment of adults with primary progressive aphasia HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Speech therapy for treatment of adults with primary progressive aphasia (...) . Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2016 Authors' conclusions Description of Technology: Speech therapy is effective for patients with acquired aphasia (e.g., after a stroke). Speech therapy in patients with primary progressive aphasia (PPA) and other forms of aphasia should be tailored to the needs of the patient, the caregiver, and the progression of the patient's underlying disease. Speech therapy is necessarily subjective, and the selection of activities during therapy

2016 Health Technology Assessment (HTA) Database.

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