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Antithyroid Drug

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121. Efficiency analysis of using tailored individual doses of radioiodine and fine tuning using a low-dose antithyroid drug in the treatment of Graves' disease. (Abstract)

Efficiency analysis of using tailored individual doses of radioiodine and fine tuning using a low-dose antithyroid drug in the treatment of Graves' disease. To evaluate the effect of using tailored individual doses of radioiodine (¹³¹I) and fine tuning using low-dose antithyroid drug (ATD) in the treatment of Graves' disease, and an attempt to establish a therapeutic strategy that can keep both high rate of euthyroidism and low incidence of hypothyroidism.The dose of radioiodine was calculated (...) using the calculated dose formula, and low-dose ATD was used as a way of fine tuning during follow-up. The intended dose of radioiodine was modified according to the patient's age at radioiodine therapy, thyroid size, and duration of hyperthyroidism before radioiodine therapy in the study group; it was set as 2.96 MBq/g of thyroid in the control group. Twenty patients with Graves' disease were nonrandomly assigned to the control group and 98 patients with Graves' disease to the study group

2011 Nuclear medicine communications Controlled trial quality: uncertain

122. Antithyroid Substances in the Treatment of Hyperthyroidism Full Text available with Trip Pro

Antithyroid Substances in the Treatment of Hyperthyroidism 14808173 2004 02 15 2018 12 01 0035-9157 43 12 1950 Dec Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Antithyroid substances in the treatment of hyperthyroidism. 937-46 DUNLOP D M DM ROLLAND C F CF eng Journal Article England Proc R Soc Med 7505890 0035-9157 0 Antithyroid Agents OM Antithyroid Agents Humans Hyperthyroidism 5120:39504:373 THYROID ANTAGONISTS THYROID, HYPERTHYROIDISM 1950 12 1 1950 12 1 0 1 1950 12 1 0 0

1950 Proceedings of the Royal Society of Medicine

123. Antithyroid Activity of N-Phthalyl Glutamic Acid Imide (K 17) Full Text available with Trip Pro

Antithyroid Activity of N-Phthalyl Glutamic Acid Imide (K 17) 13489320 2000 07 01 2018 12 01 0007-1447 1 5062 1958 Jan 11 British medical journal Br Med J Antithyroid activity of N-phthalyl glutamic acid imide (K17). 84-5 MURDOCH J M JM CAMPBELL G D GD eng Journal Article England Br Med J 0372673 0007-1447 0 Antithyroid Agents 0 Hypnotics and Sedatives 0 Imides 3KX376GY7L Glutamic Acid OM Antithyroid Agents Glutamic Acid Hypnotics and Sedatives pharmacology Imides 5833:32367:253:504 HYPNOTICS

1958 British medical journal

124. Hypothyroidism as a Late Sequela in Patients with Graves' Disease Treated with Antithyroid Agents Full Text available with Trip Pro

Hypothyroidism as a Late Sequela in Patients with Graves' Disease Treated with Antithyroid Agents In 1971, thyroid function was evaluated in 15 unselected patients whose only therapy for diffuse toxic goiter was a course of thionamide drug treatment completed 20-27 yr earlier. One patient was frankly hypothyroid by clinical and laboratory criteria. The remaining 14 patients appeared clinically euthyroid and had a normal serum thyroxine (T(4)) concentration and thyroid radioiodine uptake (RAIU (...) that progressive failure of thyroid function is a common occurence in long-standing Graves' disease, and it is suggested that this results from concomitant chronic thyroiditis. We postulate that this inherent tendency toward thyroid failure is exaggerated by surgery or radioactive iodine, explaining the progressive increase in, and inordinate frequency of, hypothyroidism after ablative modes of therapy in diffuse toxic goiter.

1979 Journal of Clinical Investigation

125. Thyroid Suppressibility: Follow-up for Two Years after Antithyroid Treatment Full Text available with Trip Pro

Thyroid Suppressibility: Follow-up for Two Years after Antithyroid Treatment In hyperthyroidism suppression and non-suppression of early radioiodine neck uptake by exogenous thyroid hormone after a course of antithyroid drugs does not indicate clearly those patients who will eventually relapse or have a remission. Sixty-four hyperthyroid patients have been followed up for two years after an 18 to 24 months' course of carbimazole. Twenty-eight patients had suppressed at the end

1971 British medical journal

126. Antithyroid treatment: a personal series. Full Text available with Trip Pro

Antithyroid treatment: a personal series. 4166808 1967 10 20 2018 11 13 0032-5473 43 497 1967 Mar Postgraduate medical journal Postgrad Med J Antithyroid treatment: a personal series. 146-9 Willcox P H PH eng Journal Article England Postgrad Med J 0234135 0032-5473 0 Antithyroid Agents 0 Imidazoles QW24888U5F Methylthiouracil IM Adolescent Adult Aged Antithyroid Agents therapeutic use Child Female Humans Hyperthyroidism drug therapy Imidazoles therapeutic use Male Methylthiouracil therapeutic

1967 Postgraduate medical journal

127. Twelve Years' Experience of Antithyroid Treatment Full Text available with Trip Pro

Twelve Years' Experience of Antithyroid Treatment 14007075 1998 11 01 2018 12 01 0032-5473 38 1962 May Postgraduate medical journal Postgrad Med J Twelve years' experience of antithyroid treatment. 275-80 WILLCOX P H PH eng Journal Article England Postgrad Med J 0234135 0032-5473 59X161SCYL Thiouracil OM Humans Hyperthyroidism therapy Thiouracil therapy HYPERTHROIDISM/therapy THIOURACIL/therapy 1962 5 1 1962 5 1 0 1 1962 5 1 0 0 ppublish 14007075 PMC2481958 Practitioner. 1953 Nov;171(1025):533

1962 Postgraduate medical journal

128. Drug-Induced Olfactory Dysfunction

. , , ) (e.g. , ) s s (Lamasil) s s V. Causes: Miscellaneous Antiproliferative drugs (e.g. Cisplatin) Antirheumatic Drugs (e.g. ) Antithyroid Medications s Anticonvulsants Azelastine ( ) Zopiclone (for ) VI. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Drug-Induced Olfactory Dysfunction." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related (...) Olfactory Dysfunction Drug-Induced Olfactory Dysfunction Aka: Drug-Induced Olfactory Dysfunction , Drug-Induced Gustatory Dysfunction , Altered Sensation of Smell due to Medication , Medication Causes of Disordered Sense of Smell , Medication Causes of Disordered Sense of Taste From Related Chapters II. Causes: Cardiovascular -Converting Enzyme Inhibitor ( ) (ARB) s s lowering agents III. Causes: Nasal Preparations Intranasal Nasal Sprays in general IV. Causes: Antimicrobials Antibiotics ( ) s (e.g

2015 FP Notebook

129. Medications Affecting Thyroid Function

Medications Affecting Thyroid Function Medications Affecting Thyroid Function Aka: Medications Affecting Thyroid Function , Drug-Induced Thyroiditis From Related Chapters II. Causes: Medications associated with Hypothyroidism Inorganic Iodide Cyanates Interleukin-2 inhibitors III. Causes: Medications associated with Hyperthyroidism Excess hormone intake Excess exposure Dietary (contains ) (contains 37% ) IV. Causes: Medications causing Thyroiditis Type 1 -induced Increased hormone synthesis (pre-existing (...) ) Treated with antithyroid medications (and s as needed for symptom control) Type 2 -induced Destructive results in increased T4 and T3 release into circulation Treated with glucocorticoids (and s as needed for symptom control) Denileukin (Ontak) CD25 cytotoxin used in CTCL, CLL, causes Autoimmune mechanism causes with or Interleukin-2 Autoimmune mechanism causes with more often than Autoimmune mechanism causes with more often than inhibitors uptake inhibition results in V. References Images: Related

2015 FP Notebook

130. Medication Causes of Myositis

of Myositis Medication Causes of Myositis Aka: Medication Causes of Myositis , Toxic Myopathy , Drug Induced Myositis , Muscle Weakness due to Medications II. Causes Antithyroid medications s Chemotherapeutics Emetine s ( agents) Interferon Leuprolide (Lupron) s Niflumic acid Phenylbutazone medications (e.g. ) s III. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Medication Causes of Myositis." Click on the image (or right (...) Medication Causes of Myositis Medication Causes of Myositis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Medication Causes

2015 FP Notebook

131. Arthritis Associated With Antithyroid Therapy in a 15-Year-Old Girl Full Text available with Trip Pro

Arthritis Associated With Antithyroid Therapy in a 15-Year-Old Girl A 15-year-old white girl with autoimmune thyroiditis developed arthritis 3 weeks after starting therapy with the antithyroid drug thiamazole. Because an adverse drug reaction of thionamide therapy was suspected, thiamazole was withdrawn, and symptoms disappeared rapidly. Thionamide therapy is indicated for hyperthyroidism and has been widely used since 1948. Reported adverse drug reactions range from mild to potentially life (...) threatening. Arthritis is an uncommon but serious side effect and can develop as a part of the antithyroid arthritis syndrome or as a part of antineutrophil cytoplasmic antibody-associated vasculitis that is induced by antithyroid drugs. Little is known about the exact pathogenesis. Therapy consists of prompt discontinuation of the drug, where upon symptoms rapidly disappear. Because of possible cross-reactivity with alternative thionamides, another form of treatment for hyperthyroidism is recommended

2011 The Journal of Pediatric Pharmacology and Therapeutics : JPPT

132. The influence of preoperative drug treatment on the extent of hyperplasia of the thymus in primary thyrotoxicosis. Full Text available with Trip Pro

The influence of preoperative drug treatment on the extent of hyperplasia of the thymus in primary thyrotoxicosis. Thymic biopsies taken from women at the beginning of the operation of subtotal thyroidectomy were studied by the point-counting histometric technique. In all patients with primary thyrotoxicosis, the thymus is hyperplastic. After pretreatment with antithyroid drugs, the pattern of thymic involution with age is similar to, but at higher levels, than that in control groups (...) of patients with non-toxic goitre in whom there is no evidence of immunological abnormality. By contrast, after propranolol pretreatment very little age involution is seen. The differences in the appearance of the thymus in female primary thyrotoxixosis patients prepared for operation with different drug treatment regimes are probably related to the pharmacological actions of the drugs and may indicate an interaction between primary immunological and secondary endocrinological factors in the disease

1975 Clinical and experimental immunology

133. Innate and drug-induced resistance to acute lung damage caused in rats by alpha-naphthyl thiourea (ANTU) and related compounds. Full Text available with Trip Pro

), with other toxic and non-toxic antithyroid drugs or with iodine or iodide--even if the rats were pretreated at an early age before susceptibility to the agent developed. ANTU-tachyphylaxis was dose-dependent. Total thyroidectomy did not affect either lung damage induced by ANTU or the resistance due to tachyphylaxis or to pretreatment with iodide or the antithyroid drugs thiourea, 1-ethyl-1-phenyl thiourea or propyl thiouracil. Neither total nor medullary adrenalectomy affected ANTU toxicity. Marked (...) Innate and drug-induced resistance to acute lung damage caused in rats by alpha-naphthyl thiourea (ANTU) and related compounds. During the 3rd and 4th weeks of life rats were highly resistant to the toxic effects of alpha-naphthyl thiourea (ANTU) and of thiourea and its derivatives but toxicity developed rapidly during the following 2 weeks. Marked resistance to lung damage by toxic thioureas could be induced in older, mature rats by pretreatment with the toxic agent itself (tachyphylaxis

1976 British journal of experimental pathology

134. Today's Drugs Full Text available with Trip Pro

Today's Drugs 4181617 1969 07 06 2013 11 21 0007-1447 2 5655 1969 May 24 British medical journal Br Med J Drug treatment of thyrotoxicosis. 496-7 eng Journal Article England Br Med J 0372673 0007-1447 0 Antithyroid Agents 0 Imidazoles 0 Iodides 0 Perchlorates 59X161SCYL Thiouracil 9679TC07X4 Iodine AIM IM Adult Antithyroid Agents therapeutic use Child Exophthalmos drug therapy Female Humans Hyperthyroidism complications drug therapy Imidazoles therapeutic use Iodides therapeutic use Iodine

1969 British medical journal

135. Prolonged drug treatment of hyperthyroidism. Full Text available with Trip Pro

Prolonged drug treatment of hyperthyroidism. 70878 1977 10 31 2018 11 13 0065-7778 88 1977 Transactions of the American Clinical and Climatological Association Trans. Am. Clin. Climatol. Assoc. Prolonged drug treatment of hyperthyroidism. 219-26 Burrows B A BA Slingerland D W DW eng Journal Article Research Support, U.S. Gov't, Non-P.H.S. United States Trans Am Clin Climatol Assoc 7507559 0065-7778 0 Antithyroid Agents 721M9407IY Propylthiouracil IM Antithyroid Agents adverse effects (...) therapeutic use Female Follow-Up Studies Humans Hyperthyroidism drug therapy Hypothyroidism etiology Male Propylthiouracil adverse effects therapeutic use Thyroid Function Tests 1977 1 1 1977 1 1 0 1 1977 1 1 0 0 ppublish 70878 PMC2441413 N Engl J Med. 1960 Jun 16;262:1228-9 13808223 Proc R Soc Med. 1961 Oct;54:869-71 13922623 Br Med J. 1964 Apr 18;1(5389):1005-10 14108470 N Engl J Med. 1964 Nov 12;271:1037-42 14195756 Scott Med J. 1964 Dec;9:505-13 14245982 Metabolism. 1972 Sep;21(9):883-94 4115791 J

1977 Transactions Of The American Clinical And Climatological Association

136. Fetal and neonatal toxicity of drugs. Full Text available with Trip Pro

Fetal and neonatal toxicity of drugs. 4169817 1968 03 30 2018 11 13 0008-4409 98 6 1968 Feb 10 Canadian Medical Association journal Can Med Assoc J Fetal and neonatal toxicity of drugs. 301-6 Yaffe S J SJ eng Journal Article Review Canada Can Med Assoc J 0414110 0008-4409 0 Analgesics 0 Anesthetics 0 Anti-Infective Agents 0 Antithyroid Agents 0 Hormones 0 Hypnotics and Sedatives 0 Sulfonamides AIM IM Abnormalities, Drug-Induced Analgesics adverse effects Anesthetics adverse effects Anti (...) -Infective Agents adverse effects Antithyroid Agents adverse effects Female Fetus drug effects Hormones adverse effects Humans Hypnotics and Sedatives adverse effects Maternal-Fetal Exchange drug effects Pregnancy Sulfonamides adverse effects 25 1968 2 10 1968 2 10 0 1 1968 2 10 0 0 ppublish 4169817 PMC1923815 J Clin Invest. 1949 Sep;28(5 Pt 2):1144-62 16695787 Pharmacol Rev. 1960 Mar;12:37-90 13796010 J Physiol. 1949 Sep;109(3-4):412-20 15407426 J Pharmacol Exp Ther. 1960 Nov;130:285-93 13723612 J

1968 Canadian Medical Association Journal

137. Drugs for Anginal Pain Full Text available with Trip Pro

Drugs for Anginal Pain 14120952 1996 12 01 2018 12 01 0008-4409 90 1964 Feb 15 Canadian Medical Association journal Can Med Assoc J DRUGS FOR ANGINAL PAIN. 491 SEGALL H N HN eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 0 Antithyroid Agents 0 Vasodilator Agents 7C0697DR9I Atropine 8017-89-8 Amyl Nitrite G59M7S0WS3 Nitroglycerin OM Amyl Nitrite Angina Pectoris Antithyroid Agents Atropine Coronary Vessels Humans Nitroglycerin Vasodilator Agents AMYL NITRITE ANGINA PECTORIS ATROPINE

1964 Canadian Medical Association Journal

138. To-day's Drugs: Treatment of Thyroid Disorders Full Text available with Trip Pro

To-day's Drugs: Treatment of Thyroid Disorders 14161993 1996 12 01 2018 12 01 0007-1447 2 5407 1964 Aug 22 British medical journal Br Med J TO-DAY'S DRUGS. TREATMENT OF THYROID DISORDERS. 493-7 WAYNE E E BLACKBURN G G DAVIS R H RH eng Journal Article England Br Med J 0372673 0007-1447 0 Antithyroid Agents 0 Iodine Isotopes OM Antithyroid Agents Female Goiter Graves Disease Heart Diseases Humans Iodine Isotopes therapeutic use Pregnancy Pregnancy Complications Thyroid Diseases Thyroidectomy

1964 British medical journal

139. Low Level Laser Therapy for Autoimmune Thyroiditis

, Outcomes Assessor) Primary Purpose: Treatment Official Title: Long-term Follow-up After Treatment of Chronic Autoimmune Thyroiditis With Low Level Laser Study Start Date : September 2014 Actual Primary Completion Date : March 2016 Actual Study Completion Date : March 2016 Resource links provided by the National Library of Medicine related topics: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: Low-level laser therapy This group of patients was treated with a continuous (...) Low Level Laser Therapy for Autoimmune Thyroiditis Low Level Laser Therapy for Autoimmune Thyroiditis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Low Level Laser Therapy for Autoimmune Thyroiditis

2014 Clinical Trials

140. Symptomatic aggravation after corticosteroid pulse therapy in definite sporadic Creutzfeldt-Jakob disease with the feature of Hashimoto¿s encephalopathy. Full Text available with Trip Pro

titers of antithyroid antibodies, corticosteroid pulse therapy is typically performed with expectations of near complete recovery from Hashimoto's encephalopathy. Herein, we provide the first case report that exhibited a negative effect of corticosteroid pulse therapy for a patient with Creutzfeldt-Jakob disease with features of Hashimoto's encephalopathy.We report a case of 59-year-old Asian woman with blurred vision, dysarthria, myoclonus, and rapidly progressive dementia. Cerebrospinal fluid (...) showed 14-3-3 protein positive. Electroencephalogram showed periodic sharp waves (1.5 Hz) at the bilateral frontal or occipital areas. Magnetic resonance imaging showed high signal intensities at the bilateral cerebral cortex, caudate nucleus, and putamen. The patient was diagnosed with probable Creutzfeldt-Jakob disease. However, serum analysis showed a high titer of antithyroid antibodies. We started corticosteroid pulse therapy with subsequent aggravation of seizure activity including generalized

2014 BMC Neurology

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