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Antibiotics in Pregnancy

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21. HTA of C-reactive protein point-of-care testing to guide antibiotic prescribing

HTA of C-reactive protein point-of-care testing to guide antibiotic prescribing Health Technology Assessment (HTA) of CRP POCT Health Information and Quality Authority i Health Technology Assessment of C-reactive protein point-of-care testing to guide antibiotic prescribing for acute respiratory tract infections in primary care settings April 2019 Health Technology Assessment (HTA) of CRP POCT Health Information and Quality Authority ii Health Technology Assessment (HTA) of CRP POCT Health (...) a range of health services, in conjunction with the Department of Health and the HSE. Health Technology Assessment (HTA) of CRP POCT Health Information and Quality Authority iv Foreword Antimicrobial resistance occurs when bacteria adapt in response to the use of medicines. When bacteria become antibiotic resistant, infections become more difficult to manage and treat. Antimicrobial resistance is a significant threat to public health, and widely acknowledged to be associated with the excessive

2019 Health Information and Quality Authority

22. The Collaborative Assessment, OTCA12, on “C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs)

The Collaborative Assessment, OTCA12, on “C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs) Dec2015 © EUnetHTA, 2015. Reproduction is authorised provided EUnetHTA is explicitly acknowledged 1 EUnetHTA Joint Action 3 WP4 Version 1.4, +31 January 2019] Rapid assessment of other technologies using the HTA Core Model ® for Rapid Relative Effectiveness Assessment C-REACTIVE PROTEIN POINT-OF-CARE (...) TESTING (CRP POCT) TO GUIDE ANTIBIOTIC PRESCRIBING IN PRIMARY CARE SETTINGS FOR ACUTE RESPIRATORY TRACT INFECTIONS (RTIS) Project ID: OTCA012 C-reactive protein point-of-care testing to guide antibiotic prescribing for acute respiratory tract infections in primary care EUnetHTA Joint Action 3 WP4 2 DOCUMENT HISTORY AND CONTRIBUTORS Version Date Description V1.0 26/10/2018 First draft. V1.1 03/12/2018 Input from co-author has been processed. V1.2 03/12/2018 Input from dedicated reviewers has been

2019 EUnetHTA

23. Antibiotics for neonates born through meconium-stained amniotic fluid. (Full text)

Antibiotics for neonates born through meconium-stained amniotic fluid. Approximately 1 in 10 pregnancies is affected by meconium passage at delivery, which can result in meconium aspiration syndrome (MAS). MAS can cause respiratory complications and, very rarely, death. Antibiotics have been prescribed for neonates exposed to meconium in amniotic fluid, with the intention of preventing infection due to potential bacterial contaminants.We conducted this review to assess the efficacy and safety (...) of antibiotics for:1. prevention of infection, morbidity, and mortality among infants born through meconium-stained amniotic fluid (MSAF) who are asymptomatic at birth; and2. prevention of infection, morbidity, and mortality among infants born through MSAF who have signs and symptoms compatible with meconium aspiration syndrome (MAS).We performed a literature search using the following databases: MEDLINE (1966 to July 2016); Embase (1980 to July 2016); the Cumulative Index to Nursing and Allied Health

2017 Cochrane

24. Antibiotic prophylaxis for operative vaginal delivery. (Full text)

infectious puerperal morbidities in women undergoing operative vaginal deliveries including vacuum or forceps deliveries, or both.We searched Cochrane Pregnancy and Childbirth's Trials Register (12 July 2017), ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP) (12 July 2017) and reference lists of retrieved studies.All randomised trials comparing any prophylactic antibiotic regimens with placebo or no treatment in women undergoing vacuum or forceps deliveries were (...) Antibiotic prophylaxis for operative vaginal delivery. Vacuum and forceps assisted vaginal deliveries are reported to increase the incidence of postpartum infections and maternal readmission to hospital compared to spontaneous vaginal delivery. Prophylactic antibiotics may be prescribed to prevent these infections. However, the benefit of antibiotic prophylaxis for operative vaginal deliveries is still unclear.To assess the effectiveness and safety of antibiotic prophylaxis in reducing

2017 Cochrane

25. Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity. (Full text)

administration of prophylactic antibiotics to women after normal (uncomplicated) vaginal birth, compared with placebo or no antibiotic prophylaxis, reduces postpartum maternal infectious morbidities and improves outcomes.We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 August 2017), LILACS, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP) (22 August 2017) and reference lists of retrieved studies.We planned to include randomised or quasi (...) Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity. Infectious morbidities contribute to considerable maternal and perinatal morbidity and mortality, including women at no apparent increased risk of infection. To reduce the incidence of infections, antibiotics are often administered to women after uncomplicated childbirth, particularly in settings where women are at higher risk of puerperal infectious morbidities.To assess whether routine

2017 Cochrane

26. Antibiotic prophylaxis for episiotomy repair following vaginal birth. (Full text)

of infection after vaginal birth is high. However, available evidence is unclear concerning the role of prophylactic antibiotics in preventing infections after an episiotomy.To assess whether routine antibiotic prophylaxis before or immediately after incision or repair of episiotomy for women with an uncomplicated vaginal birth, compared with either placebo or no antibiotic prophylaxis, prevents maternal infectious morbidities and improves outcomes.We searched the Cochrane Pregnancy and Childbirth's Trials (...) Antibiotic prophylaxis for episiotomy repair following vaginal birth. Bacterial infections occurring during labour, childbirth, and the puerperium may be associated with considerable maternal and perinatal morbidity and mortality. Antibiotic prophylaxis might reduce wound infection incidence after an episiotomy, particularly in situations associated with a higher risk of postpartum perineal infection, such as midline episiotomy, extension of the incision, or in settings where the baseline risk

2017 Cochrane

27. Pregnancy and lower urinary tract infection: opt for cefuroxime

antibiotics are cefuroxime and the combination of amoxicillin + clavulanic acid, because a large amount of data on short-term exposure is available. This includes around 400 pregnancies exposed from the first trimester to cefuroxime, and 500 exposed to the combination of amoxicillin + clavulanic acid, in which no problem was identified. In mid-2017, proprietary drugs based on single-dose fosfomycin trometamol were authorised in France for urinary tract infections in pregnant women, after having been (...) recommended by a range of institutions. This recommendation was based on a few clinical trials which showed similar efficacy to that of standard antibiotic treatment. Fosfomycin trometamol crosses the placenta and is widely distributed in the body. During the first trimester, assessment of the consequences for the unborn child of exposure to fosfomycin trometamol is based on around 150 pregnancies. No worrying safety alert has appeared, but these data are too few in number to exclude a significant risk

2019 Prescrire

28. Pregnancy and Renal Disease

Pregnancy and Renal Disease Clinical Practice Guideline Pregnancy and Renal Disease Authors: Kate Wiles - Chair NIHR Doctoral Research Fellow in Obstetric Nephrology, Guy’s and St. Thomas’ NHS Foundation Trust and King's College London Lucy Chappell Professor of Obstetrics, King's College London and Consultant Obstetrician, Guy’s and St. Thomas’ NHS Foundation Trust Katherine Clark Specialist Midwife, King’s College Hospital NHS Foundation Trust Louise Elman Expert Patient Matt Hall Consultant (...) Nephrologist, King’s College Hospital NHS Foundation Trust and King’s College London Final Version: September 2019 Review Date: September 2024 Renal Association Clinical Practice Guideline Pregnancy and Renal Disease – September 2019 2 Endorsements The National Institute for Health and Care Excellence (NICE) has accredited the process used by the Renal Association to produce its Clinical Practice Guidelines. Accreditation is valid for 5 years from January 2017. More information on accreditation can

2019 Renal Association

29. Interventions during pregnancy to prevent preterm birth: an overview of Cochrane systematic reviews. (Full text)

, bedrest for women with singleton pregnancy and antibiotic prophylaxis during the second and third trimester were of no effect or equivalent to a comparator.Possible benefitFour SRs found possible benefit in: group antenatal care for all pregnant women; antibiotics for pregnant women with asymptomatic bacteriuria; pharmacological interventions for smoking cessation for pregnant women who smoke; and vitamin D supplements alone for women without pre-existing conditions such as diabetes.Possible harmOne (...) ; and fetal and umbilical Doppler for high-risk pregnant women.Clear evidence of harmNo included SR reported clear evidence of harm.No effect or equivalenceFor pregnant women at high risk of PTB, antibiotic prophylaxis during the second and third trimester was of no effect or equivalent to a comparator.Possible benefitOne SR reported possible benefit with cervical cerclage for women with singleton pregnancy and high risk of PTB.Possible harmOne SR reported possible harm associated with a reduced schedule

2018 Cochrane

30. Is there an association between chronic endometritis and recurrent pregnancy loss or preterm birth? And does treatment with antibiotics improve pregnancy outcome?

Is there an association between chronic endometritis and recurrent pregnancy loss or preterm birth? And does treatment with antibiotics improve pregnancy outcome? Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2016 PROSPERO

31. Antibiotics in Pregnancy

Antibiotics in Pregnancy Antibiotics in Pregnancy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Antibiotics in Pregnancy Antibiotics (...) in Pregnancy Aka: Antibiotics in Pregnancy , Antifungal Medications in Pregnancy , Antiparasitic Medications in Pregnancy , Antiviral Medications in Pregnancy II. Background Pregnancy Categories will be replaced on medication bottles with specific warnings and precautions by 2020 in U.S. Although are no longer FDA designated, they are included here As of 2018, succinct guidance (to replace ABCDX) on specific drugs in pregnancy is lacking III. Class B: No risk in controlled animal studies Topical Agents

2018 FP Notebook

32. Antibiotic Therapy in Preterm Premature Rupture of the Membranes

PPROM at 32 weeks' gestation, antibiotics should be administered to women who are not in labour in order to prolong pregnancy and to decrease maternal and neonatal morbidity (I-A). 2. The use of antibiotics should be gestational-age dependent. The evidence for benefit is greater at earlier gestational ages (<32 weeks) (I-A). 3. For women with PPROM at >32 weeks' gestation, administration of antibiotics to prolong pregnancy is recommended if fetal lung maturity cannot be proven and/or delivery (...) Antibiotic Therapy in Preterm Premature Rupture of the Membranes No. 233-Antibiotic Therapy in Preterm Premature Rupture of the Membranes - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 39, Issue 9, Pages e207–e212 No. 233-Antibiotic Therapy in Preterm Premature Rupture of the Membranes x Mark H. Yudin , MD Toronto, ON x Julie van Schalkwyk , MD Vancouver, BC x Nancy Van Eyk , MD Halifax, NS No. 233, September 2017

2017 Society of Obstetricians and Gynaecologists of Canada

33. Care of Women with Obesity in Pregnancy

Care of Women with Obesity in Pregnancy Care of Women with Obesity in Pregnancy Green-top Guideline No. 72 November 2018 Please cite this paper as: Denison FC, Aedla NR, Keag O, Hor K, Reynolds RM, Milne A, Diamond A, on behalf of the Royal College of Obstetricians and Gynaecologists. Care of Women with Obesity in Pregnancy. Green-top Guideline No. 72. BJOG 2018DOI: 10.1111/1471-0528.15386 RCOG Green-top Guidelines Care of Women with Obesity in Pregnancy FC Denison, NR Aedla, O Keag, K Hor, RM (...) Reynolds, A Milne, A Diamond, on behalf of the Royal College of Obstetricians and Gynaecologists Correspondence: Royal College of Obstetricians and Gynaecologists, 27 Sussex Place, Regent’s Park, London NW1 4RG. Email: clinicaleffectiveness@rcog.org.uk This is the second edition of this guideline. The ?rst edition was published in 2010 as a joint guideline with the Centre of Maternal and Child Enquiries under the title ‘Management of Women with Obesity in Pregnancy’. Executive summary Prepregnancy care

2018 Royal College of Obstetricians and Gynaecologists

34. Management of Group B Streptococcal Bacteriuria in Pregnancy

, and Costs The recommendations in this guideline are designed to help clinicians identify pregnancies in which it is appropriate to treat GBS bacteriuria to optimize maternal and perinatal outcomes, to reduce the occurrences of antibiotic anaphylaxis, and to prevent increases in antibiotic resistance to GBS and non-GBS pathogens. No cost-benefit analysis is provided. Recommendations 1. Treatment of any bacteriuria with colony counts ≥100 000 CFU/mL in pregnancy is an accepted and recommended strategy (...) and includes treatment with appropriate antibiotics (II-2A). 2. Women with documented group B streptococcal bacteriuria (regardless of level of colony-forming units per mL) in the current pregnancy should be treated at the time of labour or rupture of membranes with appropriate intravenous antibiotics for the prevention of early-onset neonatal group B streptococcal disease (II-2A). 3. Asymptomatic women with urinary group B streptococcal colony counts <100 000 CFU/mL in pregnancy should not be treated

2018 Society of Obstetricians and Gynaecologists of Canada

35. Management of Cardiovascular Diseases during Pregnancy

Management of Cardiovascular Diseases during Pregnancy We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy | European Heart Journal | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter search input Article Navigation Close (...) mobile search navigation Article navigation 07 September 2018 Article Contents Article Navigation 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy Vera Regitz-Zagrosek Chairperson Corresponding authors. Vera Regitz-Zagrosek, Charité Universitaetsmedizin Berlin, Institute for Gender in Medicine, CCR, DZHK, partner site Berlin, Hessische Str 3-4, 10115 Berlin, Germany, Tel: +49 30 450 525 288, Fax: +49 30 450 7 525 288, E-mail: . Search for other works by this author

2018 European Society of Cardiology

36. Pregnancy

cause serious adverse pregnancy outcomes for both mother and child including preterm birth and small-for-gestational-age babies. Interventions used to prevent RUTI in women who are pregnant can be pharmacological (antibiotics) or non-pharmacological (cranberry products, acupuncture, probiotics and behavioural (...) modifications). So far little is known about the best way to prevent RUTI in pregnant women. OBJECTIVES: To assess the effects of interventions for preventing RUTI in pregnant women.The (...) Pregnancy Top results for pregnancy - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Latest and Greatest

37. Bacterial vaginosis in pregnancy and risk of spontaneous preterm delivery

Bacterial vaginosis in pregnancy and risk of spontaneous preterm delivery Bacterial vaginosis, proposal for the Danish guideline meeting 2015 (version 190214) Page 1 Bacterial vaginosis in pregnancy and risk of spontaneous preterm delivery Approved at the obstetrical guideline-meeting January 2015 Danish Society of Obstetrics and Gynecology (DSOG) Update February 2019 The Lancet has now published reference 31b, by Subtil et al. (2018). The 2015 version of the DSOG guideline included (...) The objective of this guideline is to evaluate bacterial vaginosis in pregnancy concerning • Different treatments for prevention of preterm delivery. • Screening of pregnant women with low as well as high risk of sPTD. • Stratification into gestational ages below and above 16 weeks. • Diagnostic methods. Key words Bacterial vaginosis, vaginal pH, pH-glove, vaginal discharge, Nugent score, Amsel score, Gardnerella vaginalis, Mobiluncus species, preterm delivery, preterm birth, GRADE, clindamycin

2019 Nordic Federation of Societies of Obstetrics and Gynecology

38. Group B streptococci during pregnancy

is recommended to be treated at the time of diagnosis C UTI with GBS is defined as the occurrence of = 10 4 CFU/ml together with symptoms of UTI B The indication for Intrapartum Antibiotic Prophylaxis (IAP) will depend on the examination and treatment regime chosen (see below), when symptomatic or asymptomatic GBS bacteriuria has been found during the current pregnancy. D The recommended antibiotic regime in asymptomatic GBS bacteriuria as well as symptomatic GBS UTI 1. Tbl Phenoxymetylpenicillin 1 MIE x 3 (...) of treatment B Random find of GBS in a vaginal swab from the vagina or the cervix during pregnancy should not be treated C Intrapartum antibiotic prophylaxis (IAP) General screening for GBS antepartum or intrapartum is not recommended D IAP is recommended to women, colonized with GBS at the time of birth, as it reduces the vertical transmission of GBS to the child and reduce the incidence of early onset neonatal GBS disease. A IAP is always given to women, who, in a prior pregnancy, gave birth to a child

2019 Nordic Federation of Societies of Obstetrics and Gynecology

39. Syphilis in pregnancy

· If at birth CNS or CSF abnormal, repeat CSF at 6 months for VDRL, cell count and protein Precautionary single dose at discharge · Expert practitioner may consider single precautionary dose of antibiotic if serological follow-up is uncertain and congenital syphilis considered unlikely (but cannot be excluded with certainty) Drug of choice · Benzathine penicillin 50 mg/kg IM onceQueensland Clinical Guideline: Syphilis in pregnancy Refer to online version, destroy printed copies after use Page 5 of 31 (...) Syphilis in pregnancy Maternity and Neonatal C linical G uideline Queensland Health Syphilis in pregnancy Queensland Clinical Guideline: Syphilis in pregnancy Refer to online version, destroy printed copies after use Page 2 of 31 Document title: Syphilis in pregnancy Publication date: December 2018 Document number: MN18.44-V1-R23 Document supplement: The document supplement is integral to and should be read in conjunction with this guideline. Amendments: Full version history is supplied

2019 Queensland Health

40. Immune Modulating Therapies in Pregnancy and Lactation

to demonstrate an association ( , ). Aminosalicylates Sulfasalazine, a combination of salicylate and a sulfa antibiotic, is used most commonly during pregnancy to treat inflammatory bowel disease. Although both sulfasalazine and its metabolite, sulfapyridine, cross the placenta, teratogenic effects have not been demonstrated ( , ). Sulfasalazine inhibits dihydrofolate reductase. Whether the addition of folic acid supplementation is important among women taking sulfasalazine is not known ( ) and is not part (...) Immune Modulating Therapies in Pregnancy and Lactation Immune Modulating Therapies in Pregnancy and Lactation - ACOG Menu ▼ Immune Modulating Therapies in Pregnancy and Lactation Page Navigation ▼ Number 776 Committee on Obstetric Practice Society for Maternal-Fetal Medicine This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Obstetric Practice in collaboration with committee member Alison G. Cahill, MD, MSCI, and the Society

2019 American College of Obstetricians and Gynecologists

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