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Antibiotic Food Interactions

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181. European Society of Endocrinology Clinical practice guidelines for the care of girls and women with Turner syndrome

recommend a formal audiometric evaluation every 5 years regardless of the initial age at diagnosis, initial hearing threshold levels, karyotype and/or presence of a mid-frequency sensorineural hearing loss, to assure early and adequate technical and other rehabilitative measures (⨁⨁◯◯). R 6.2. We recommend aggressive treatment of middle-ear disease and otitis media (OM) with antibiotics and placement of myringotomy tubes as indicated (⨁⨁◯◯). R 6.3. We recommend screening for hypothyroidism at diagnosis

2017 European Society of Endocrinology

182. Midostaurin for the indication of Acute Myeloid Leukaemia

DFS disease-free survival DOICU Declaration of interest and confidentiality undertaking E etoposide ECOG Eastern Cooperative Oncology Group EEA European Economic Area EFS event-free survival EHA European Hematology Association ELN European LeukemiaNet EMA European Medicines Agency EPAR European Public Assessment Report ESMO European Society for Medical Oncology EU European Union Ev everolimus FAS full analysis set FDA US Food and Drug Administration FLAG-IDA fludarabine + cytarabine + idarubicin (...) -dose PTJA01 - Midostaurin with standard chemotherapy in FLT3 positive acute myeloid leukaemia Version 1.3, Novermber 2017 EUnetHTA Joint Action 3 WP4 13 cytarabine consolidation chemotherapy, and for patients in complete response followed by midostaurin single-agent maintenance therapy, for adults with newly diagnosed AML who are FLT3 mutation positive. Midostaurin gained regulatory approval from the US Food and Drug Ad- ministration (FDA) on 28th April 2017 and from Swissmedic on 4th May 2017

2017 EUnetHTA

183. Antibacterial-coated sutures versus non-antibacterial-coated sutures for the prevention of abdominal, superficial and deep, surgical site infection (SSI)

low risk of bias RCTs 83 Table 19: The length of hospital stay in triclosan-coated vs non-antibacterial coated sutures patient groups 85 Table 20: The proportion of patients requiring secondary surgery for wound-related complications of surgery 86 Table 21: The incidence of complete abdominal wound dehiscence within 30 days of surgery and incisional hernia during the period of study follow-up 87 Table 22: Causative microorganism of SSI and the use of systemic antibiotic therapy within 30 days (...) Economic Area EFF Clinical Effectiveness domain EP European Pharmacopoeia EQ-5D EuroQol five dimensions questionnaire ESBL Extended spectrum beta-lactamase ETH Ethical analysis EU European Union EUnetHTA European network for Health Technology Assessment FDA Food and Drug Administration FiO2 Fraction of inspired oxygen GDFT Goal-directed fluid therapy GDG Guidelines Development Group GI Gastro-intestinal GL Guideline GMDN Global medical device nomenclature GRADE The Grading of Recommendations Assessment

2017 EUnetHTA

184. Antimicrobial stewardship: systems and processes for effective antimicrobial medicine use

of infection. 1.1.35 When a decision to prescribe an antimicrobial has been made, take into account the benefits and harms for an individual patient associated with the particular antimicrobial, including: possible interactions with other medicines or any food and drink the patient's other illnesses, for example, the need for dose adjustment in a patient with renal impairment any drug allergies (see the NICE guideline on drug allergy; these should be documented in the patient's record) the risk (...) (including antibiotics) in children, young people and adults. It aims to change prescribing practice to help slow the emergence of antimicrobial resistance and ensure that antimicrobials remain an effective treatment for infection. Who is it for? Health and social care practitioners Organisations commissioning, providing or supporting the provision of care People who are taking antimicrobials and their families and carers. Antimicrobial stewardship: systems and processes for effective antimicrobial

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

185. Diarrhoea in Adult Cancer Patients: ESMO Clinical Practice Guidelines

the development of the diarrhoea over the previ- ous days and, particularly, the frequency of bowel movements during the past 24 hours. Stool consistency and admixture of blood, mucus or pus should be noted. It is also important to distin- guish diarrhoea from steatorrhoea, according to stool characteris- tics. Questions should cover possible causes other than cancer and oncological therapies [food and ?uid intake in the last few days, re- cent travel, recent use of antibiotics, use of proton pump inhibitors (...) -induceddiarrhoea The widespread use of RT in pelvic cancer treatment (e.g. gynae- cological and gastrointestinal cancers) is related to the increasing incidence of radiation-induced side effects. The RT-induced damage can be the direct result of the energy absorption from in- cident radiation or the effect of the free radicals realised by the interaction of radiation with cellular water. Moreover, damage of stem cells within intestinal crypts during replication or differenti- ation causes a reduction or a loss

2018 European Society for Medical Oncology

186. Delirium in Adult Cancer Patients: ESMO Clinical Practice Guidelines

for de- lirium. In addition, most studies in cancer patients have explored a range of psychiatric diagnoses rather than addressing factors speci?c to delirium. As a consequence, the number of patients with delirium in these studies has often been insuf?cient to pre- cisely determine associated risk factors. A multifactorial model for hospitalised patients aged 70 - years has been proposed [5]. The model involves the interaction between ‘baseline vulnerability’ and ‘precipitating factors or insults (...) on the ‘psycho- motor activity’ item of the MDAS) 48 hours before death, com- pared with 13/56 (17.3%) (P ¼ 0.009) receiving 80% have abnormalities on electro- encephalogram [87, 88]. Although it is common practice to treat the infection associated with delirium, there is no randomised study data to speci?cally support this practice. In a prospective study of 237 cancer patients admitted to hospice, delirium that was due to an infection and was treated with standard antibiotics had a lower rate

2018 European Society for Medical Oncology

187. Complex regional pain syndrome in adults. UK guidelines for diagnosis, referral and management in primary and secondary care 2018 (2nd edition)

report suffering from interactions with health professionals who do not believe that their condition is ‘real’. 13 Independently, it is recognised that some people self-induce signs with the aim of making their limb appear as though they have CRPS. 14 Limb signs (such as swelling/sweating and colour/temperature changes) usually reduce with time, even where pain, and motor symptoms persist. 15,16 However, such reduction of limb signs is in itself not ‘recovery’. Where pain persists, the condition

2018 British Society of Rehabilitation Medicine

188. Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management

and possible interactions with other drugs). [new 2014] [new 2014] Offer a full-dose PPI (see table 2 in appendix A) long-term as maintenance treatment for people with severe oesophagitis, taking into account the person's preference and clinical circumstances (for example, tolerability of the PPI, underlying health conditions and possible interactions with other drugs), and the acquisition cost of the PPI. [new 2014] [new 2014] Do not routinely offer endoscopy to diagnose Barrett's oesophagus, but consider (...) , including advice on healthy eating, weight reduction and smoking cessation. [2004] [2004] 1.2.2 Advise people to avoid known precipitants they associate with their dyspepsia where possible. These include smoking, alcohol, coffee, chocolate, fatty foods and being overweight. Raising the head of the bed and having a main meal well before going to bed may help some people. [2004] [2004] 1.2.3 Provide people with access to educational materials to support the care they Gastro-oesophageal reflux disease

2014 National Institute for Health and Clinical Excellence - Clinical Guidelines

189. The Association of Coloproctology of Great Britain and Ireland Consensus Guidelines in Surgery for Inflammatory Bowel Disease

to respond with poor prognostic factors , . A particular case for early referral for consideration for colectomy may be made in the frail patient with multiple comorbidities who, while not necessarily a good candidate for surgery, nevertheless still has much less reserve to withstand further deterioration after prolonged attempts at medical salvage , . Optimizing the IBD patient for elective surgery requires resolution of sepsis after radiological intervention and antibiotic therapy, reversal (...) effective in treating cases that are refractory to first‐line agents [e.g. glucocorticoids, 5‐aminosalicylates (5‐ASAs), antibiotics] . The failure of medical treatment can be either primary nonresponsive or secondary (subsequent loss of response). The primary response is usually evaluated after 8–12 weeks from the start of treatment . Surgery is recommended for such patients and for those who are noncompliant with medical treatment or develop severe complications from its continuation , . Statement 2.1

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2018 Association of Coloproctology of Great Britain and Ireland

190. Persistent Pain with Breastfeeding

Atopic dermatitis (eczema): This condition occurs in womenwithanatopictendencyandmaybetriggered byskinirritantsandotherfactorssuchasweatherand temperature change. 19 B Irritant contact dermatitis: Common offending agents include friction, infant (oral) medications, solid foods (consumed by the infant), breast pads, laundry detergents, dryer sheets, fabric softeners, fragrances, and creams used for nipple soreness. 18 B Allergic contact dermatitis: Common offending agents include lanolin, antibiotics (...) , shooting, dull, aching) B Pain severity using rating scale, such as 0–10 B Associated signs and symptoms (skin changes, nipple color change, nipple shape/appearance after feeding, fever) B Exacerbating/ameliorating factors (cold, heat, light touch, deep pressure) B Treatment thus far (analgesia, including nonsteroidal anti-in?ammatory drugs and/or narcotic prepara- tions), antibiotics, antifungals, steroids, herbs, lubri- cants, other supplements Maternal history B Complications during pregnancy

2016 Academy of Breastfeeding Medicine

191. Argus II Retinal prosthesis

Products, Inc. Implantation of the Argus II Retinal Prosthesis System can be performed by a single surgeon in a two-hour outpatient procedure under general anaesthesia. 3 Details regarding the surgery are as follows: ? At commencement of the implant procedure, antibiotics and steroids are administered by intravenous injection. ? In phakic eyes (eyes with a lens) the lens is removed. ? An incision is made into the conjunctiva surrounding the cornea, exposing the underlying sclera and extra-ocular (...) ) and affixed to the retina in the macula with a retinal tack. ? The extraocular portion of the ribbon cable is then sutured to the sclera and all incisions are sutured. ? A transplanted scleral tissue graft (or alternative) is sutured over the electronics package to reduce the likelihood of conjunctival irritation. ? At completion of the surgery, steroids, antibiotics and an anaesthetic are injected under the conjunctiva. Argus® II Retinal Prosthesis: Update August 2016 3 For approximately two weeks after

2016 COAG Health Council - Horizon Scanning Technology Briefs

192. Low-density lipoprotein cholesterol goals: still not in patients' best interest

death, CHD death, death from any cause, and fatal MI) were significantly different between the groups. The authors pre-specified a considerable number of subgroup analyses, and although they must always be interpreted with caution, there was a significant subgroup interaction for age dichotomized at 75 years (p for interaction 0.005, with directionality favoring those 75 years old or older) and diabetes mellitus (p for interaction 0.023, with directionality favoring those with diabetes). Notably (...) interest for the results of properly-designed outcomes trials, as the Food and Drug Administration (FDA)—and even some of those who mistakenly espouse a return to LDL-C goals—have plainly noted, we currently lack reliable outcomes data for the PCSK9 inhibitors, and we also need further evaluation of potential adverse effects of these novel agents. What we need in the interim are evidence-conscious providers who remain cognizant of these issues. Regressing to LDL-C goals is not the answer, and the fact

2016 Evidence-Based Medicine (Requires free registration)

193. WHO recommendations on antenatal care for a positive pregnancy experience

A supplements A.4: Vitamin A supplementation is only recommended for pregnant women in areas where vitamin A deficiency is a severe public health problem, h to prevent night blindness. i Context-specific recommendation a. A healthy diet contains adequate energy, protein, vitamins and minerals, obtained through the consumption of a variety of foods, including green and orange vegetables, meat, fish, beans, nuts, whole grains and fruit. b. The equivalent of 60 mg of elemental iron is 300 mg of ferrous sulfate (...) . v Not recommended C. Preventive measures Recommendation Type of recommendation Antibiotics for asymptomatic bacteriuria (ASB) C.1: A seven-day antibiotic regimen is recommended for all pregnant women with asymptomatic bacteriuria (ASB) to prevent persistent bacteriuria, preterm birth and low birth weight. Recommended Antibiotic prophylaxis to prevent recurrent urinary tract infections C.2: Antibiotic prophylaxis is only recommended to prevent recurrent urinary tract infections in pregnant women

2016 World Health Organisation Guidelines

194. Vitamin D supplements may reduce the chance of developing a chest infection

by viruses, though some infections due to bacteria can require antibiotics. In 2016 the Scientific Advisory Committee on Nutrition (SACN) review on vitamin D and health recommended adults take 10µg vitamin D per day throughout the year based on the benefits for musculoskeletal health. The SACN at the time, found conflicting evidence on whether vitamin D supplements reduce risk of respiratory tract infection or other non-musculoskeletal outcomes and recommended more research into these areas (...) analysed separately, or for other outcomes of interest, like hospital admissions, school or work absence. It’s uncertain whether the findings could lead to a modification to the general population recommendations on vitamin D supplementation, as many following PHE advice will be already taking supplements. Another potential avenue the authors suggest considering for population health is fortification of foods with vitamin D. This is not something that is currently recommended or covered

2018 NIHR Dissemination Centre

195. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications

, mural, infection, diagnosis, bacteremia, case definition, epidemiology, risks, demographics, injection drug use, echocardiography, microbiology, culture-negative, therapy, antibiotic, antifungal, antimicrobial, antimicrobial resistance, adverse drug effects, drug monitoring, outcome, meta-analysis, complications, abscess, heart failure, embolic events, stroke, conduction abnormalities, survival, pathogens, organisms, treatment, surgery, indications, valve replacement, valve repair, ambulatory care (...) that has embolized, or an intracardiac abscess specimen; or pathological lesions; vegetation or intracardiac abscess confirmed by histological examination showing active endocarditis Clinical criteria 2 Major criteria, 1 major criterion and 3 minor criteria, or 5 minor criteria Possible IE 1 Major criterion and 1 minor criterion, or 3 minor criteria Rejected Firm alternative diagnosis explaining evidence of IE; or resolution of IE syndrome with antibiotic therapy for ≤4 d; or no pathological evidence

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2016 Infectious Diseases Society of America

196. Clinical Practice Guidelines From the Cystic Fibrosis Foundation for Preschoolers With Cystic Fibrosis

by bronchoscopy is not recommended. However, bronchoscopy with BAL should be considered in patients with a change in respiratory status that does not respond to antibiotics directed toward pathogens isolated from OP swabs. : Recommendations 14–15. Pulmonary Therapeutics Pulmonary Exacerbations Based on our current understanding of early disease progression, the association of pulmonary exacerbations with worse outcomes, and evidence of improvement with antibiotic treatment, , – the recommendation (...) for preschoolers with CF experiencing an exacerbation is oral, inhaled, and/or intravenous antibiotic treatment. Defining a pulmonary exacerbation is beyond the scope of this article; however, outlines the recommended approach to preschool-aged children with increased respiratory symptoms. There are no randomized clinical trials of pulmonary exacerbation treatment in preschool-aged children with CF; thus, these guidelines for management were based on consensus recommendations, and management decisions should

2016 Cystic Fibrosis Foundation

197. U.S. Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of nontuberculous mycobacteria in individuals with cystic fibrosis

in individuals with CF include: increases in environmental exposure to NTM through more permissive temperature settings of home water heaters and more contact with shower aerosols, , increased antibiotic usage creating more NTM favourable lung niches, greater chronic use of medications that might impair host immunity to NTM, and/or spread of NTM through person-to-person transmission. , NTM-PD in individuals with CF NTM can cause progressive inflammatory lung damage, a condition termed ‘NTM pulmonary disease (...) to cause clinical disease in humans and in their response to specific antibiotics, correct species identification of NTM isolates is clinically important. Moreover, in the case of M. abscessus , the ability to identify isolates to the subspecies level ( M. a. abscessus, M. a. bolletii , M. a. massiliense ) may predict treatment response and potentially permit targeted therapy. M. a. massiliense harbours a partial erm 41 gene deletion, preventing inducible macrolide resistance, , and leads to more

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2016 Cystic Fibrosis Foundation

198. 2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients

chemotherapy of high emetic risk and dexamethasone plus aprepitant or aprepitant alone to prevent delayed nausea and vomiting in cisplatin-treated/ and AC-treated patients, respectively [ ]. Since then two new neurokinin (NK) 1 RAs, netupitant and rolapitant, have been approved by the US Food and Drug Administration (FDA, netupitant as NEPA combined with palonosetron and rolapitant) and the European Medicines Agency (EMA, netupitant as NEPA combined with palonosetron) and an i.v. formulation of aprepitant (...) antineoplastic agents with a moderate emetogenic potential [ ]. Concerning NK 1 RAs, a study in 16 young, healthy volunteers showed that the 5-day NK 1 receptor binding affinity of a single dose of oral aprepitant 165 mg was as high as a single i.v. dose of fosaprepitant 150 mg [ ]. It is unknown if the results can be extrapolated to cancer patients, who are older than the healthy volunteers in the study and typically require 4–6 different drugs each day, heightening the risk of drug–drug interactions

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2016 International Society for Oral Oncology

199. SCAI Expert Consensus Statement: 2016 Best Practices in the Cardiac Catheterization Laboratory

remains unproven, it is reasonable but not manda- tory for hats and masks to be worn for every procedure. Antibiotic prophylaxis is not indicated for routine coro- nary procedures, but is often used before permanent implantations other than coronary stents and, at some institutions,beforevascularclosure device (VCD)place- ment in high-risk subsets, such as diabetics or immuno- compromisedpersons(38). Radiation Exposure All CCL procedures should be performed with the goal of keeping radiation doses (...) are utilized, ambulation is restricted for 1–4 hr postprocedure [49,50]. Generally, studies show that while use of VCD is noninferior to manual compres- sion with respect to access site complications, and infection rate may be higher, the time to hemostasis and earlier ambulation are potential advantages [45,51]. Resterilization of the access site, the use of new gloves, and the use of antibiotics prior to VCD insertion may reduce infection risk in high-risk subsets. Hemostasis by manual compression

2016 Society for Cardiovascular Angiography and Interventions

200. SCAI/CCAS/SPA Expert Consensus Statement for Anesthesia and Sedation Practice: Recommendations for Patients Undergoing Diagnostic and Therapeutic Procedures in the Pediatric and Congenital Cardiac Catheterization Laboratory

. Allergies, including drug, food, latex, and contrast. 3. Antibiotic requirements. 4. Heparin plan. 5. Blood availability. 6. Availability of vasopressor medications and resusci- tation equipment. 7. Disposition postprocedure (inpatient unit, intermediate- care unit, or intensive-care unit). Postprocedure 1. Adverse events. 2. Equipment issues. 3. Specimens labeled and sent. 4. Detailed sign-out to floor, intermediate-care unit, intensive-care unit, or PACU. 5. Necessary postprocedure tests, including (...) . FOSTERING AN ENVIRONMENT OF PARTNERSHIP IN DECISION MAKING FOR OPTIMAL PATIENT CARE, OPEN COMMUNICATION AND COORDINATION BETWEEN CARDIOLOGISTS AND ANESTHESIOLOGISTS First and foremost, patient care is about patient safe- ty and achieving the desired outcome. In a multi- professional procedure, optimal outcomes are best ac- complished by face-to-face/personal interactions be- tween team members. Interventional cardiologists, anesthesiologists and surgeons (for hybrid procedures) must spend time

2016 Society for Cardiovascular Angiography and Interventions

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