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Antepartum Depression

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161. Antidepressant Use During Pregnancy: Considerations for the Newborn Exposed to SSRIs/SNRIs

to serotonin reuptake inhibitors and benzodiazepines using population-based health data. Birth Defects Res B Dev Reprod Toxicol 2008;83(1):68-76. 10 Pedersen LH, Henriksen TB, Vestergaard M, Olsen J, Bech BH. Selective serotonin reuptake inhibitors in pregnancy and congenital malformations: population based cohort study. BMJ 2009;339:b3569-b3575. 11 Chung TKH, Lau TK, Yip ASK, Chiu HFK, Lee DTS. Antepartum depressive symptomatology is associated with adverse obstetric and neonatal outcomes. Psychosom Med (...) attention, such as depression and anxiety, are common during pregnancy. While there are risks to pharmaceutical treatment during pregnancy, untreated or incompletely managed depr ession also carries risks for the exposed newbor n. After car eful consideration of the risks and benefits of pharmaceutical treatment, many women and their caregivers decide to continue treatment with SSRIs/SNRIs during their pregnancy. While most newborns born to women who continue SSRI/SNRI treatment during pregnancy

2013 British Columbia Perinatal Health Program

162. Investigation and Management Small-for-Gestational-Age Fetus

assessment of wellbeing with umbilical artery Doppler unless they develop specific pregnancy complications, for example antepartum haemorrhage or hypertension. However, they should be offered a scan for fetal size and umbilical artery Doppler during the third trimester. Serial ultrasound measurement of fetal size and assessment of wellbeing with umbilical artery Doppler should be offered in cases of fetal echogenic bowel. Abdominal palpation has limited accuracy for the prediction of a SGA neonate (...) need to be assessed on an individual basis. The evidence for an association with asthma, thyroid disease, inflammatory bowel disease and depression is less convincing. Studies report a weak or non–significant association with LBW but do not differentiate between the effect on SGA and preterm birth, and with confidence intervals [CIs] often crossing one. Therefore, if uncomplicated and adequately treated, these are not considered to be risk factors for a SGA fetus. 20,21 Maternal risk factors

2013 Royal College of Obstetricians and Gynaecologists

163. Pre-conception - advice and management

planning a pregnancy; and managing women who are underweight prior to conception. New sections on rheumatological conditions and inflammatory bowel disease have also been added. Creation of a general section on mental health issues that incorporates previous information on depression, bipolar disorder, and psychosis and schizophrenia. Minor changes to the management recommendations on alcohol advice; managing a woman with diabetes planning to conceive; referral of women with asthma for preconception

2017 NICE Clinical Knowledge Summaries

165. Caesarean section

individual CS. [new 2011] [new 2011] 1.4.4 1.4.4 Preoper Preoperativ ative testing and prepar e testing and preparation for CS ation for CS 1.4.4.1 Pregnant women should be offered a haemoglobin assessment before CS to identify those who have anaemia. Although blood loss of more than 1000 ml is infrequent after CS (it occurs in 4–8% of CS) it is a potentially serious complication. [2004] [2004] 1.4.4.2 Pregnant women having CS for antepartum haemorrhage, abruption, uterine rupture and placenta praevia (...) ] 1.7.1.8 Healthcare professionals caring for women who have had a CS should inform women that after a CS they are not at increased risk of difficulties with breastfeeding, depression, post-traumatic stress symptoms, dyspareunia and faecal incontinence. [2004] [2004] 1.7.1.9 While women are in hospital after having a CS, give them the opportunity to discuss with healthcare professionals the reasons for the CS and provide both verbal and printed information about birth options for any future pregnancies

2011 National Institute for Health and Clinical Excellence - Clinical Guidelines

166. Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients.

hypertension (gestational hypertension, preeclampsia, chronic hypertension and chronic hypertension with superimposed preeclampsia). Singleton living fetus. Exclusion Criteria: Maternal medical disorders rather than hypertension. Fetal congenital anomalies. Rupture of membrane. Antepartum hemorrhage (placenta previa or accidental hemorrhage). The maternal administration of respiratory depressants within 2 hours from the delivery of the fetus (e. g., opioid analgesic ) Contacts and Locations Go

2018 Clinical Trials

167. Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa

: Not yet recruiting First Posted : May 31, 2018 Last Update Posted : May 31, 2018 See Sponsor: Assiut University Information provided by (Responsible Party): ramy nasser, Assiut University Study Details Study Description Go to Brief Summary: Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 28+0 weeks of pregnancy and till delivery of the fetus. it occurs in 3-5% of pregnancies and is an important cause of perinatal and maternal morbidity and mortality (...) : No Additional relevant MeSH terms: Layout table for MeSH terms Obstetric Labor, Premature Placenta Previa Obstetric Labor Complications Pregnancy Complications Placenta Diseases Magnesium Sulfate Nifedipine Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Anesthetics Central Nervous System Depressants Anti-Arrhythmia Agents Anticonvulsants Calcium Channel Blockers Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Calcium-Regulating

2018 Clinical Trials

168. Prevalence and risk factors of gestational diabetes mellitus: findings from a universal screening feasibility program in Lima, Peru. (Full text)

and was associated with maternal obesity, family history of diabetes and antepartum depression among Peruvian women. Intervention programs aimed at early diagnoses and management of GDM need to take maternal obesity, family history of diabetes and antepartum depression into account. (...) was conducted among 1300 pregnant women attending a prenatal clinic in Lima, Peru. GDM was diagnosed using an Oral Glucose Tolerance Test (OGTT) performed between 24 and 28 gestational weeks using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Depression status was assessed using the Patient Health Questionnaire-9. Multivariate logistic regression models were used to identify risk factors of GDM.Approximately 16% of pregnant women were diagnosed with GDM

2018 BMC Pregnancy and Childbirth PubMed abstract

169. Buprenorphine vs Buprenorphine/Naloxone on the Effects of Maternal Symptomatology

to Primary Outcome Measures : Compliance antepartum [ Time Frame: From entry into the study until delivery (through study completion, an average of 9 months which is duration of the pregnancy) ] To compare compliance with buprenorphine versus buprenorphine/naloxone medication-assisted treatment (MAT) in pregnant women. Compliance will include the incidence of urine toxicology testing positive for illicit substances during prenatal care and at the time of admission for delivery. Compliance postpartum (...) [ Time Frame: 2 month period postpartum ] To compare compliance with buprenorphine versus buprenorphine/naloxone medication-assisted treatment (MAT) in the postpartum period. Compliance will include the incidence of urine toxicology testing positive for illicit substances from the time of discharge from the hospital following the delivery over a 2 month period postpartum (postpartum period). Dosing antepartum [ Time Frame: From entry into the study until delivery (through study completion, an average

2018 Clinical Trials

170. HIV Exposure and Formula Feeding Predict Under-2 Mortality in HIV-Uninfected Children, Botswana. (Full text)

zidovudine, and 1% took <2 weeks of any antiretrovirals antepartum. Twenty four-month vital status was available for 888 (99.4%) children. HIV-exposed uninfected children had a significantly higher risk of death compared with children of HIV-uninfected mothers (5.0% vs 1.8%) (adjusted hazard ratio 3.27, 95% CI 1.44-7.40). High collinearity between maternal HIV status and child feeding method precluded analysis of these factors as independent predictors of mortality. Preterm birth, low birth weight (...) , and congenital anomaly were also associated with mortality (in separate analyses), but maternal socioeconomic factors, depression, substance use, and social support were not significant predictors.The strongest predictors of 24-month mortality among children in Botswana were HIV exposure and formula feeding, although the relative contribution of these factors to child health could not be separated.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 Journal of Pediatrics PubMed abstract

171. Evaluation of Copeptin Levels in Elective Cesarean Section With Different Anesthetic Technique

Inclusion Criteria: 18-40 years of age ASA I-II 36-40 gestational weeks BMI ≤ 40 Undergoing elective cesarean section Exclusion Criteria: Coagulopathy Known central or peripheral nerve disease fetal anomalies birth weight less than 2000 grams and above 4500 grams, infants with a risk of meconium or amniotic fluid aspiration kidney failure, diabetes mellitus, hypertension, cardiac disease, antepartum hemorrhage, asthma bronchiole, Rh incompatibility, congenital malformations Contacts and Locations Go (...) Device Product: No Keywords provided by Ece YAMAK ALTINPULLUK, Istanbul University: copeptin levels Cesarean section general anesthesia spinal anesthesia Additional relevant MeSH terms: Layout table for MeSH terms Diabetes Insipidus Fetal Distress Kidney Diseases Urologic Diseases Pituitary Diseases Endocrine System Diseases Signs and Symptoms Anesthetics Arginine Vasopressin Central Nervous System Depressants Physiological Effects of Drugs Hemostatics Coagulants Vasoconstrictor Agents Antidiuretic

2018 Clinical Trials

172. Tranexamic Acid in Pregnancies With Vaginal Bleeding

Description Go to Brief Summary: Tranexamic acid has been proposed and used for prevention and management of antepartum and postpartum hemorrhage. Condition or disease Intervention/treatment Phase Vaginal Bleeding During Pregnancy Drug: Tranexamic Acid Not Applicable Detailed Description: Bleeding during pregnancy is associated with a three- to fourfold increase in perinatal mortality. Hemorrhage in pregnancy is characterized by activation of the fibrinolytic system. Tranexamic acid is a potent (...) Model: Single Group Assignment Intervention Model Description: Tranexamic acid was prescribed for women with abnormal vaginal bleeding in the first trimester less than 20 weeks gestation (threatened and recurrent miscarriage) and Antepartum hemorrhage (abruption , placenta previa, and unknown causes for vaginal bleeding) Masking: None (Open Label) Primary Purpose: Treatment Official Title: Tranexamic Acid in Pregnancies With Early and Late Onset Vaginal Bleeding:One Arm Clinical Trial Actual Study

2018 Clinical Trials

173. Is partners’ mental health and well-being affected by holding the baby after stillbirth? Mothers’ accounts from a national survey (Full text)

to have held their baby. Higher gestational age, shorter time interval between antepartum death and delivery, and mother's holding the baby all predicted a higher rate of partner's holding. There was a consistent negative effect of holding the baby across mental health and well-being outcomes, although after adjustment only higher odds of depression (OR 2.72, 95% CI 1.35-5.50) and post-traumatic stress type symptoms (OR 1.95, 95% CI 1.01-3.78) at 3 months were significantly associated with having held (...) the baby following stillbirth.This study is the first to assess the impact of holding the baby on partners' mental health and well-being. The prevalence of depression and anxiety were high, and the negative effects of holding the baby were significant 3 months later.

2018 Journal of Reproductive and Infant Psychology PubMed abstract

174. Onset of Labour Epidural Analgesia With Different Concentration Bupivacaine and Different Doses of Sufentanyl

Description: Pregnant women Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria:patients ASA physical status 1 or 2; early labour (cervical dilation 5 cm or less); singleton fetus; gestational age > 36 weeks; and normal fetal heart rate (FHR) tracing. - Exclusion Criteria:severe preeclampsia;antepartum haemorrhage; ASA 3 or more; chronic pain; substance abuse;contraindications to epidural analgesia; allergies to local anaesthetics or fentanyl; body mass index (BMI) over 40; and previous (...) : January 10, 2018 Last Update Posted: January 10, 2018 Last Verified: January 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Bupivacaine Sufentanil Anesthetics, Local Anesthetics Central Nervous System Depressants Physiological Effects of Drugs Sensory System Agents Peripheral Nervous System Agents Analgesics, Opioid Narcotics Analgesics Adjuvants

2018 Clinical Trials

175. Chronic Medical Conditions and Perinatal Mental Illness: A Systematic Review and Meta-Analysis. (Full text)

using DerSimonian and Laird random effects models. The review included 16 papers representing 12 studies and 1,626,260 women. CMCs overall were associated with peripartum mental illness overall (adjusted pooled odds ratios (aPOR) = 1.43, 95% confidence interval (CI): 1.25, 1.63). CMCs overall were associated with antepartum (aPOR = 1.41, 95% CI: 1.10, 1.81) and postpartum mental illness separately (aPOR = 1.44, 95% CI: 1.13, 1.85) and with peripartum depression (aPOR = 1.45, 95% CI: 1.25, 1.67

2018 American Journal of Epidemiology PubMed abstract

176. Diagnosis and Treatment of Fetal Cardiac Disease (Full text)

assessment are reviewed, including the use of advanced ultrasound techniques, fetal magnetic resonance imaging, and fetal magnetocardiography and electrocardiography for rhythm assessment. Models for parental counseling and a discussion of parental stress and depression assessments are reviewed. Available fetal therapies, including medical management for arrhythmias or heart failure and closed or open intervention for diseases affecting the cardiovascular system such as twin–twin transfusion syndrome (...) assessment. Models for parental counseling and a discussion of parental stress and depression assessments are reviewed. Available fetal therapies, including medical management for arrhythmias or heart failure and closed or open intervention for diseases affecting the cardiovascular system such as twin–twin transfusion syndrome (TTTS), lung masses, and vascular tumors, are highlighted. Experimental catheter-based intervention strategies to prevent the progression of disease in utero also are discussed

2014 American Heart Association PubMed abstract

177. Royal Flying Doctor Service Western Operations Clinical manual part 1.Clinical guidelines

Version 6.0 Clinical Manual Issue Date: January 2013 Part 1 - Clinical Guidelines Table of Contents 10 OBSTETRIC 1 10.1 Pre-term Labour and Tocolysis 1 10.2 Pre-Eclampsia 4 10.3 Eclampsia 6 10.4 Antepartum Haemorrhage 7 10.5 Post-Partum Haemorrhage 8 10.6 Epidurals In-Flight 10 10.7 Obstetric Trauma 11 11 PAEDIATRICS 1 11.1 Paediatric Upper Airway Obstruction 1 11.2 Gastroenteritis / Dehydration In Children 3 11.3 Neonate Retrievals 5 11.4 Intranasal Fentanyl 7 12 RESPIRATORY 1 12.1 Pulmonary Embolism (...) elevation = 1mm in 2 contiguous limb leads ? Persistent ST elevation = 2mm in 2 contiguous chest leads ? New left bundle branch block (LBBB) ? Changes consistent with posterior infarct (tall R in V1, deep anterior ST depression, ST elevation in V4 R) ? ECG changes of right ventricular infarct (ST elevation in leads aVR and V4R) NSTEMI Consistent history without ECG changes consistent with STEMI, plus positive troponin and positive creatine kinase (CK). Angina ? High Risk, (positive troponin but negative

2014 Clinical Practice Guidelines Portal

179. Improving the Reporting of Clinical Trials of Infertility Treatments (IMPRINT): modifying the CONSORT statement

restriction (FGR) h Delivery Cesearean section/operative deliveries Small or large for gestational age (SGA/LGA), i preterm delivery (PTD), j anomalies detected by obstetrical screening Postpartum and neonatal/infancy Thromboembolism, postpartum depression, Lactation rates Anomalies detected after birth, neonatal intensive care unit admission, length of stay a A death of male or female parent or fetus/infant participating in trials should be reported. b OHSS (ovarian hyperstimulation syndrome

2014 Society for Assisted Reproductive Technology

180. Breastfeeding-Friendly Physician?s Office: Optimizing Care for Infants and Children

, of?ce staff, and families. (For the purposes of thisdocument‘‘physician’’referstoanyonewhoisrendering the primary medical care to the breastfeeding dyad, both the mother antepartum and the dyad postpartum. In differ- ent countries and cultures that could be a doctor, a midwife, or another healthcare professional. All should strive for a ‘‘Breastfeeding-Friendly Practice’’ in which to care for these families.) Breastmilk substitutes Infant formula, glucose water, or other liquids given in place (...) , re?ux, normal stool and voiding patterns, maintaining lactation when separated from the infant (for example, during illness, prematurity, or return to work), breastfeeding in public, postpartum depression, maternal medication use, and maternal illness during breastfeeding). (I) 8. Allow and encourage breastfeeding in the waiting room. Display signs in the waiting area encouraging mothers to breastfeed (Figs. 1 and 2). Provide a com- fortable private area to breastfeed for those mothers who prefer

2013 Academy of Breastfeeding Medicine

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