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41. Horner Syndrome from a Pediatric Otolaryngology Perspective. (PubMed)

and excisional biopsy revealed a poorly differentiated neuroblastoma. Case #2 is a 9-year-old female with anisocoria appearing after suffering a severe playground injury. Case #3 is a 3-year-old-male who developed ptosis and anisocoria following re-excision of a recurrent cervical lymphatic malformation.Pediatric Horner syndrome may be a benign finding that is easily overlooked but may reflect a serious underlying condition. Otolaryngologists should be aware of the pathophysiology and differential diagnosis

2019 Rhinology and Laryngology

42. Can the Red Reflex Test Detect Unequal Refractive Error? (PubMed)

was symmetric or asymmetric. The patient was then dilated, and cylcoplegic refraction was performed by an attending pediatric ophthalmologist. Exclusion criteria included the presence of strabismus, anisocoria, previous intraocular surgery, media opacity, leukocoria, or nystagmus. Sensitivity was compared with a null hypothesized value of 50% using a 1-sided binomial test.Ninety-two patients with a mean age of 7.3 years (range 3 months to 16 years) were enrolled. With spherical anisometropia greater than

2019 Journal of Pediatrics

43. "Crying without tears" as an early diagnostic sign-post of triple A (Allgrove) syndrome: two case reports. (PubMed)

of the AAAS gene. The second patient, an 8 months old boy was presented because of anisocoria and unilateral optic atrophy. MRI revealed cerebellar vermis hypotrophy. Psychomotor retardation, failure to thrive, and frequent vomiting lead to further diagnostic work-up. Achalasia was diagnosed radiologically. In addition, the mother mentioned absence of tears since birth leading to the clinical diagnosis of triple A syndrome. In contrast to the first cases genetic testing was negative.These two patients

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2018 BMC Pediatrics

44. Stereopsis Simulating Small-Aperture Corneal Inlay and Monovision Conditions. (PubMed)

Stereopsis Simulating Small-Aperture Corneal Inlay and Monovision Conditions. To analyze stereoscopic vision under a broad range of experimental conditions simulating small-aperture corneal inlay and monovision conditions.A total of 10 patients participated in the study. The anisocoria generated by corneal inlays was simulated by using a small-aperture contact lens fitted on the non-dominant eye. Visual acuity, contrast sensitivity function, visual discrimination capacity (halo perception (...) ), and stereoacuity tests were performed under natural conditions or when the non-dominant eye wore the small-aperture contact lens under two conditions: induced anisocoria and induced anisocoria combined with monovision (using two add-powers: +0.75 and +1.25 diopters [D]). Stereoscopic vision and binocular summation were analyzed under those experimental conditions and for far, intermediate, and near vision.The results showed a deterioration in stereoacuity with respect to natural conditions, being significant

2018 Journal of Refractive Surgery

45. Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification

sulfate or epinephrine. Pediatric age group (less than 18 years old). Pupil abnormalities, such as anisocoria or neurological disorders. Associated glaucoma, uveitis, corneal, retinal or optic nerve disease. Cases scheduled for phacoemulsification under general anaesthesia (to exclude possible ocular and systemic effects or interactions of anaesthetic agents). Patients with bleeding tendency or on anti-coagulant therapy (because peribulbar and subconjunctival injections are used). Contacts

2018 Clinical Trials

46. Isolated Horner syndrome as a rare initial presentation of nasopharyngeal carcinoma: a case report (PubMed)

with oculosympathetic denervation.A 33-year-old Asian man with a heavy smoking habit presented with a 3-week history of left ptosis and no other complaints. His visual acuity was 20/20 bilaterally. An ophthalmic examination was significant for mild ptosis of his left eyelid and anisocoria (smaller left pupil), which was greater in the dark. Both pupils reacted to light briskly without an afferent pupillary defect. Anhidrosis was found on the medial side of the left forehead. A 10% cocaine test was positive. At his

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2018 International medical case reports journal

47. Point-of-Care Ultrasound Diagnosis of Retinoblastoma in the Emergency Department. (PubMed)

Point-of-Care Ultrasound Diagnosis of Retinoblastoma in the Emergency Department. An 18-month-old girl presented to the emergency department with the chief complaint of squinting. The right eye demonstrated esotropia, heterochromia, and anisocoria. Ocular point-of-care ultrasound facilitated the rapid diagnosis of retinoblastoma, which was confirmed by computed tomography scan and orbital magnetic resonance imaging.

2018 Pediatric Emergency Care

48. Acute intraparenchymal cerebral haemorrhage in an Iberian golden eagle – a case report (PubMed)

Acute intraparenchymal cerebral haemorrhage in an Iberian golden eagle – a case report In birds there are reports of intracranial lesions but not of the clinical, computed tomographic and histopathologic features of acute intraparenchymal cerebral haemorrhage in Iberian golden eagle.The following report describes a case of a 30-year-old Iberian golden eagle (Aquila chrysaetos homeyeri) with no history of trauma, presented with acute opisthotonus, left head tilt and circling, anisocoria

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2018 BMC veterinary research

49. Diagnosis and management of pediatric cervical vagal schwannoma. (PubMed)

Diagnosis and management of pediatric cervical vagal schwannoma. Schwannomas arising from the vagus nerve are extremely rare in children, with only 15 cases reported in the world literature. We describe a pediatric case of cervical vagal nerve schwannoma successfully treated with cranial nerve-sparing surgery. Our patient presented extensive mass in the right side of the neck with ipsilateral Horner's syndrome. Her first sign, anisocoria, was diagnosed at the age of 1.5 y, making her

2018 International Journal of Pediatric Otorhinolaryngology

50. A Method of Managing Severe Traumatic Brain Injury in the Absence of Intracranial Pressure Monitoring: The Imaging and Clinical Examination Protocol. (PubMed)

literature standard, it warrants careful evaluation. We present the ICE protocol in detail and analyze the demographics, outcome, treatment intensity, frequency of intervention usage, and related adverse events in the ICE-protocol cohort. The 167 ICE protocol patients were young (median 29 years) with a median Glasgow Coma Scale motor score of 4 but with anisocoria or abnormal pupillary reactivity in 40%. This protocol produced outcomes not significantly different from those randomized to the monitor

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2018 Journal of neurotrauma Controlled trial quality: uncertain

51. Retrobulbar steatitis and meningitis/empyema secondary to right otitis media, right otitis interna and an inflammatory polyp in a cat (PubMed)

and fungal culture of material from the middle ear. A 6-year-old female neutered domestic-short-haired cat presented with right-sided exophthalmos and resistance to retropulsion. Anisocoria, reduced corneal sensation and oculocephalic movements and low Schirmer tear test (STT1) were found. An MRI revealed the right external ear canal and tympanic bulla to be fluid filled with presence of a thickened contrast-enhancing mucosa. Contrast enhancement extended into the calvarium, as marked thickening

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2018 Open veterinary journal

52. The PUPIL Study

pathway. The SFM is a qualitative test, and relies upon visualising no pupillary constriction or immediate or delayed pupillary dilation; if either of these responses is observed, an RAPD is believed to be present. The SFM requires a trained examiner and many potential sources of error may confound the results, including anisocoria, off-axis pupil illumination, and unequal retinal bleaching. Pupil abnormalities may be subtle and easily missed using the SFM. Automated pupilometers allow examiners

2017 Clinical Trials

53. Treatment of the superior sagittal sinus and transverse sinus thrombosis associated with intracranial hemorrhage with the mechanical thrombectomy and thrombolytics: Case report. (PubMed)

to neurosurgical intensive care unit (NICU), patient appeared anisocoria (R/L:4.0/2.5 mm), bilateral light reflexes disappeared, then we took a CT reexamination revealed intraparenchymal hemorrhage increased, brain edema was aggravated at the left temporal lobe, and mild midline shift. Subsequently, we performed decompressive hemicraniectomy and puncture the hematoma supplemented by B ultrasonic. Anticoagulation treatment was initiated 24 hours after surgery, and follow-up DSA showed gradually improved patency

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2017 Medicine

54. Clinical characteristics and temporal profile of recovery in patients with favorable outcomes at 6 months after severe traumatic brain injury. (PubMed)

to the point of following commands beyond 2 weeks after the injury was seen in 14.8% of patients, who experienced significantly longer durations of intracranial pressure monitoring (p = 0.001) and neuromuscular blockade (p < 0.001). In comparison with patients with moderate disability, patients with good recovery had a higher initial GCS score (p = 0.01), lower incidence of anisocoria at admission (p = 0.048), and a shorter ICU stay (p < 0.001) and total hospital stay (p < 0.001). There was considerable

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2017 Journal of Neurosurgery

55. Acute intractable headache and oculomotor nerve palsy associated with nicorandil: A case report. (PubMed)

report on a 59-year-old woman who presented to the ED with an intractable headache and right ptosis. She had previously received nicorandil for paroxysmal atrial fibrillation in the cardiology clinic. Her vital signs were stable upon ED arrival. Neurological examination revealed a mild anisocoria with a sluggish response to light stimuli in the right eye. Adduction, supraduction, and infraduction were also limited in the right eye. Nuchal rigidity was not apparent. An urgent brain magnetic resonance

2017 American Journal of Emergency Medicine

56. A Window to the Brain: Neuro-Ophthalmology for the Primary Care Practitioner. (PubMed)

A Window to the Brain: Neuro-Ophthalmology for the Primary Care Practitioner. Visual symptoms, including acute monocular visual loss, papilledema, visual field deficits, anisocoria, limitations of eye movements, and nystagmus, can be the presenting feature of a wide range of important neurologic diseases. It is important for primary care clinicians to be to be able to direct appropriate initial diagnostic assessment, treatment, and referral for further evaluation of these conditions.Crown

2017 American Journal of Medicine

57. 2017 PEMPix Online Case #2: Big Circle

on the ipsilateral side and resting left sided esotropia Partial palsy of CN 3 resulted in ptosis and anisocoria Additionally, the patient was bradycardic on presentation, which was likely due to the oculocardiac reflex. A decreased pulse rate occurs when traction is applied to the extra-ocular muscles or when the eyeball is compressed, and is mediated by nervous fibers that connect the cranial nerves with the vagus and parasympathetic nervous system. His CT scan revealed a well circumscribed, hyperdense mass

2017 PEM Blog

58. Intracranial pressure in patients undergoing decompressive craniectomy: new perspective on thresholds. (PubMed)

and analyzed. From these findings, ICP thresholds discriminating favorable from unfavorable outcome were calculated using conditional inference tree analysis. Additionally, survival analysis was performed using the Kaplan-Meier method. Prognostic factors were assessed via univariate analysis and multivariate logistic regression. Favorable outcome was defined as a score of 0-4 on the modified Rankin Scale. RESULTS Multivariate logistic regression revealed that anisocoria, diagnosis, and ICP values differed

2017 Journal of Neurosurgery

59. Munchausen by proxy syndrome mimicking systemic autoinflammatory disease: case report and review of the literature. (PubMed)

infections and reversible anisocoria in the absence of laboratory evidence of systemic inflammation. After two and a half years of extensive diagnostic work-up and multiple empirical therapies, a final diagnosis of Munchausen by proxy syndrome (MBPS) was established.The diagnosis of SAID needs to be carefully reassessed if measurable systemic inflammation is missing, and MBPS should be included in the differential diagnosis.

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2017 Pediatric Rheumatology

60. A Case of Synchronised Pupillary and Nasal Cycling: Evidence for a Central Autonomic Pendulum? (PubMed)

A Case of Synchronised Pupillary and Nasal Cycling: Evidence for a Central Autonomic Pendulum? We previously reported that some healthy individuals show alternating anisocoria. We now describe one such individual who also exhibits a classic nasal cycle (alternating periods of nasal congestion and decongestion). We made measurements of his pupil asymmetry and nasal asymmetry at 21 different time points and found that these variables were always synchronised such that greater nasal airflow

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2017 Neuro-Ophthalmology

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