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Androgenic Alopecia

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61. Alopecia, androgenetic - male

Alopecia, androgenetic - male Alopecia, androgenetic - male - NICE CKS Share Alopecia, androgenetic - male: Summary Androgenetic alopecia describes a distinctive pattern of hair loss, which may occur in genetically predisposed men and is thought to be androgen dependent. In men, hair loss usually initially involves the front and sides of the scalp and progresses towards the back of the head. The underlying pathological process involves pigmented terminal hairs gradually being replaced (...) standards NICE Quality Standards No NICE Quality Standards were found during the review of this topic. Background information Background information Definition What is androgenetic alopecia? Androgenetic alopecia describes a distinctive pattern of hair loss which may occur in genetically predisposed people and is thought to be androgen dependent. In men, hair loss usually initially involves the front and sides of the scalp and progresses towards the back of the head. In women, hair loss is usually more

2018 NICE Clinical Knowledge Summaries

62. Hair micro transplant using follicular unit extraction technique for alopecia

. Noviembre de 2015. Authors' conclusions Scarce evidence of low methodological quality was found, assessing the follicular unit extraction technique in hair micro transplant with aesthetic purposes in androgen-related alopecia and other indications. The studies identified do not show relevant benefits. No randomized clinical trials have been identified, and there are no studies comparing this surgical technique with the standard medical treatment for alopecia. This technique is not considered (...) Hair micro transplant using follicular unit extraction technique for alopecia Hair micro transplant using follicular unit extraction technique for alopecia Hair micro transplant using follicular unit extraction technique for alopecia Macchiavello D, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L., Hernandez Vásquez A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA

2015 Health Technology Assessment (HTA) Database.

63. Androgens in Women: Androgen mediated skin disease and patient evaluation (Part I). (Abstract)

cutaneous conditions in women, including acne, hirsutism, and female pattern hair loss (FPHL) - androgen mediated cutaneous disorders (AMCDs). However, the role of androgens in the pathophysiology of these diseases is complicated and incompletely understood. In the first article in this Continuing Medical Education series, we discuss the role of the skin in androgen production as well as the impact of androgens on the skin in women. Specifically, we review the necessary, but insufficient role (...) Androgens in Women: Androgen mediated skin disease and patient evaluation (Part I). Androgens are produced throughout the body in steroid-producing organs, such as the adrenal glands and ovaries, as well as in other tissues, like the skin. Several androgens are found normally in women, including dehydroepiandrosterone (DHEA), dehydroepiandrosterone-sulfate (DHEA-S), testosterone, dihydrotestosterone (DHT), and androstenedione. These androgens are essential in the development of several common

2018 Journal of American Academy of Dermatology

64. Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial. Full Text available with Trip Pro

Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial. We conducted a 16-week double-blind randomized controlled single-center trial to evaluate the safety and efficacy of dermal rice bran supercritical CO2 extract (RB-SCE) in the treatment of androgenic alopecia. Fifty alopecia patients were randomly assigned to the experimental and placebo groups. The experimental group received a dermal (...) application of 0.5% RB-SCE (8 mL/d) to the head skin for 16 weeks while the control group received a dermal application of placebo. Changes in hair count, diameter, and density were evaluated with a Folliscope(®). Patient satisfaction was evaluated via questionnaire and clinical photographs were rated by dermatologists. The results showed that RB-SCE significantly increased hair density and hair diameter in male subjects. Patient satisfaction and the evaluation of photographs by dermatologists also

2015 Biological & pharmaceutical bulletin Controlled trial quality: uncertain

65. The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia

per month or a placebo for 16 weeks. Hair count and thickness will be primary outcomes. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 38 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Supportive Care Official Title: The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia Study (...) The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2015 Clinical Trials

66. Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. (Abstract)

Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. Both androgenetic alopecia (AGA) and carcinoma of the prostate (CaP) or benign prostatic hyperplasia (BPH) are androgen-dependent disorders.To investigate the relationships between male androgenetic alopecia, androgen receptor (AR) gene polymorphism (SNP rs6152) and clinical characteristics of BPH and prostate cancer.Overall, 309 male subjects (...) with prostate disease (BPH or CaP) were examined. We evaluated the standard grades of AGA (I-VII) by Hamilton-Norwood classification and 195 patients were also assessed by phototrichogram. Prostate-specific antigen (PSA) and testosterone levels were also measured. Polymorphism rs6152 of the AR was evaluated from blood samples by PCR-RFLP. Data were statistically evaluated.The expected positive correlation between age and AGA grade and the expected negative correlation between hair density and age

2015 Journal of the European Academy of Dermatology and Venereology

67. The diagnosis of androgenetic alopecia in children: Considerations of pathophysiological plausibility. (Abstract)

The diagnosis of androgenetic alopecia in children: Considerations of pathophysiological plausibility. Androgenetic alopecia (AGA), one of the most common causes of hair loss in men and women, is an infrequent cause of alopecia in children. In AGA, patients generally start noticing hair thinning after the onset of puberty due to progressive miniaturisation of the hair follicle which leads to vellus transformation of terminal hair. However, the occurrence of prepubertal AGA has rarely been (...) reported in the literature. The pathophysiology of AGA is tightly linked to androgen hormones; prepubertal children do not usually produce significant amounts of adrenal or gonadal androgens. When it does occur, an underlying abnormality should be suspected. Secondary causes of AGA must be excluded when evaluating a patient before the appearance of puberty. Premature puberty, polycystic ovarian syndrome and other causes of hyperandrogenism can present with hair loss in an androgenetic pattern

2019 Australasian Journal of Dermatology

68. Types of hairline recession in androgenetic alopecia and perceptions of aging in Asian males. (Abstract)

a mystery.To investigate and quantify the effect of different types of hairline recession on PFA in East Asian young males of different age groups.Thirty non-bald males were selected and divided equally into three groups (20s, 30s, and 40s). With the aid of modern software, the frontoparietal area of facial images from 30 experimenters was modified into three basic types of hair loss (M2 , C2 , and U2 ) according to the basic and specific classification of androgenic alopecia. In a web-based survey (...) Types of hairline recession in androgenetic alopecia and perceptions of aging in Asian males. Cranial hair loss is one of the characteristics of age. Hairline recession has been confirmed adversely to affect the perceptions of age in Western males. However, comparatively little is known about the effect of frontal recession on the perceived facial age (PFA) of East Asian males. Moreover, specific roles of different types of hairline recession in PFA of different age groups still remain

2019 International Journal of Dermatology

69. All about hair loss (alopecia) - Deutsche Welle expert interview

Treatments: Drugs Minoxidil shampoo Patients can buy an OTC shampoo with an ingredient called minoxidil. Minoxidil (Rogaine) fights androgenic alopecia in both men and women. It's still not entirely clear how minoxidil works. Used properly -- twice a day, massaged deep into the scalp -- it slows new hair loss. Two-thirds of men do get acceptable hair growth. "It is not something a bald person would use, but someone starting to go bald would use it. The goal is to maintain the hair you have." An example (...) All about hair loss (alopecia) - Deutsche Welle expert interview CasesBlog - Medical and Health Blog: All about hair loss (alopecia) - Deutsche Welle expert interview Health News Updated Daily by Internist and Allergist at Cleveland Clinic Florida Pages All about hair loss (alopecia) - Deutsche Welle expert interview Dr. Andreas Finner (Trichomed Praxis Berlin) talks about what everyone can do to keep a full head of hair and about the best methods for treating hair loss: Today's Hair-Loss

2015 CasesBlog - Medical and Health Blog

70. what is the evidence base for procerin in preventing hair loss in male / androgenic hair loss?

what is the evidence base for procerin in preventing hair loss in male / androgenic hair loss? what is the evidence base for procerin in preventing hair loss in male / androgenic hair loss? - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe (...) across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com what is the evidence base for procerin in preventing hair loss in male / androgenic hair loss? What is the evidence base for procerin in preventing hair loss in male/androgenic hair loss? ATTRACT

2011 TRIP Answers

71. The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-Reductase inhibition, reversal of secondary microinflammation and improving insulin resistance. (Abstract)

The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-Reductase inhibition, reversal of secondary microinflammation and improving insulin resistance. Research in the past half a century has gradually sketched the biological mechanism leading to androgenetic alopecia (AGA). Until recently the aetiological paradigm has been too limited to enable intelligent commentary on the use of folk remedies to treat or reduce the expression of this condition. However, our understanding (...) is now at a point where we can describe how some folk remedies work, predict how effective they will be or why they fail.The new paradigm of AGA is that inheritance and androgens (dihydrotestosterone) are the primary contributors and a secondary pathology, microinflammation, reinforces the process at more advanced stages of follicular miniaturisation. The main protagonist to microinflammation is believed to be microbial or Demodex over-colonisation of the infundibulum of the pilosebaceous unit, which

2018 Journal of Ethnopharmacology

72. Nanofat Grafting for Treatment of Androgenetic Alopecia

Androgenic Alopecia Procedure: Nanofat grafting Not Applicable Detailed Description: The investigators will treat the hair loss area of a patient by processed nanofat grafting. The participants were asked to come back 1、3、6、9、12 months after treatment for further follow-up. Before and after the treatment, the hair and follicular will be assessed subjectively by satisfaction assessment, dermatoscope. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial (...) Nanofat grafting processed autologous Nanofat will be injected into the area of the scalp with androgenic alopecia. Procedure: Nanofat grafting hair loss area will be treated by processed autologous Nanofat grafting Outcome Measures Go to Primary Outcome Measures : Dermatoscope [ Time Frame: Baseline and at1,3,6,9,12 months after the treatment ] the density of hair follicle and diameter of hair will be analized by dermatoscope before and after the treatment of Nanofat grafting. Other Outcome Measures

2018 Clinical Trials

73. The Effect of Platelet Rich Plasma on Non-scarring Alopecia

visits per patient. Data collection will include representative photographs of the scalp and measurements of hair thickness. The results from the two groups will then be compared. In summary, all study participants will have a screening visit before enrollment, four study visits for sub-dermal scalp injections, and one final assessment visit at week 40. Condition or disease Intervention/treatment Phase Androgenetic Alopecia Alopecia Device: Platelet Rich Plasma Drug: Normal saline Not Applicable (...) an informed consent form Must be female between the ages of 18 and 65 years at the time of consent Must be able to adhere to the study visit schedule and other protocol requirements Documented platelet count above 150,000 platelets per microliter within 6 months prior to enrollment Exclusion Criteria: Previous or current use in the last 1 year of finasteride, minoxidil topical or oral, or spironolactone A diagnosis of non-androgenic alopecia (i.e: another diagnosis for the alopecia ) No Baseline ferritin

2018 Clinical Trials

74. Evaluating Platelet-Rich Therapy for Facial Aesthetics and Alopecia: A Critical Review of the Literature. (Abstract)

Evaluating Platelet-Rich Therapy for Facial Aesthetics and Alopecia: A Critical Review of the Literature. Despite the growing popularity of platelet-rich plasma, existing evidence supporting its efficacy remains controversial due to the lack of large-scale studies and standardized protocols for preparation and application. This article reviews its use in facial rejuvenation, fat grafting, acne scarring, and androgenic alopecia. Emphasis is placed on comparing methods of platelet-rich plasma (...) preparation and application across studies.A systematic review was performed for articles published between 2006 and 2015. All clinical studies and case reports that addressed platelet-rich plasma alone and/or in combination with fat grafting for facial rejuvenation, acne scarring, or androgenic alopecia were included.Of the 22 articles included in the analysis, seven studies used platelet-rich plasma alone for facial rejuvenation, seven in combination with fat grafting, two for treatment of acne scarring

2018 Plastic and reconstructive surgery

75. Androgenetic Alopecia and the JAK-STAT Pathway

): Aya AlOrbani, Cairo University Study Details Study Description Go to Brief Summary: It is a well known fact that the JAK-STAT pathway plays a pivotal role in the pathogenesis of alopecia areata. Both phosphorylated STAT 1 and 3 have been found to be upregulated in the disease (Xing et al., 2014). However, whether this pathway plays a role in other hair loss disorders remains unclear.(Sivan et al., 2015). Our study aims at assessing STAT3 levels in male patients with androgenetic alopecia. We (...) hypothesize that STAT3 levels will be elevated (due to a previous study proving that JAK-STAT pathway is involved in non-immune mediated hair loss in mice (Sivan et al., 2015)). . Condition or disease Intervention/treatment Androgenetic Alopecia Other: Punch skin biopsy Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 25 participants Observational Model: Case-Control Time Perspective: Retrospective Official Title: Assessment of the Role of the JAK

2018 Clinical Trials

76. A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia

of study medication Clinical diagnosis of alopecia areata or other non-AGA forms of alopecia Scalp hair loss on the treatment area, due to disease, injury, or medical therapy History of surgical correction (e.g., hair transplantation, scalp reduction) of hair loss on the scalp Previous exposure to SM04554 Use of any products (e.g., finasteride, minoxidil, platelet rich plasma, biotin) or devices (e.g., laser light therapy) purported to promote scalp hair growth within 24 weeks prior to the start (...) of the study Use of anti-androgenic therapies (e.g., spironolactone, flutamide, cyproterone acetate, cimetidine) within 12 weeks prior to the start of the study Use of medications that potentially cause drug-induced hair loss (e.g., depotestosterone, haloperidol, methotrexate, methylprednisolone, prednisone, testosterone, divalproex sodium) within 12 weeks prior to the start of the study Current use of an occlusive wig, hair extensions, or hair weaves History of hypersensitivity or allergies to any

2018 Clinical Trials

77. Study of BYL719 (Alpelisib) in Combination With Androgen Receptor Inhibitor (Enzalutamide) in Patients With Androgen Receptor (AR)-Positive and PTEN Positive Metastatic Breast Cancer

Study of BYL719 (Alpelisib) in Combination With Androgen Receptor Inhibitor (Enzalutamide) in Patients With Androgen Receptor (AR)-Positive and PTEN Positive Metastatic Breast Cancer Study of BYL719 (Alpelisib) in Combination With Androgen Receptor Inhibitor (Enzalutamide) in Patients With Androgen Receptor (AR)-Positive and PTEN Positive Metastatic Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration (...) or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of BYL719 (Alpelisib) in Combination With Androgen Receptor Inhibitor (Enzalutamide) in Patients With Androgen Receptor (AR)-Positive and PTEN Positive Metastatic Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators

2017 Clinical Trials

78. Systemic causes of hair loss. (Abstract)

Systemic causes of hair loss. Hair loss is both a common chief complaint by patients and a clinical challenge for physicians, especially general practitioners, yet few dermatological problems yield as much patient satisfaction when resolved as hair loss. The diagnosis is often attributed to androgen-related hair loss, while other causes, some of which are life-threatening but treatable, are overlooked. We searched for relevant literature on hair loss and supported these findings with our (...) clinical experience to identify seven major systemic etiologies of hair loss, ranging from infectious agents to consumption of unsafe supplements. Many causes are only described in the literature through case studies, though some original articles and meta-analyses are available. Careful history taking, proper examination techniques, and judicious use of laboratory tests are essential to reach at the correct diagnosis in a cost-effective manner when performing patient work-up. Such methodical

2016 Annals of Medicine

79. Characteristics of Men Who Report Persistent Sexual Symptoms after Finasteride Use for Hair Loss. Full Text available with Trip Pro

Characteristics of Men Who Report Persistent Sexual Symptoms after Finasteride Use for Hair Loss. Some men who use finasteride for hair loss report persistent sexual and other symptoms after discontinuing finasteride therapy.To determine whether these persistent symptoms after discontinuation of finasteride use are due to androgen deficiency, decreased peripheral androgen action, or persistent inhibition of steroid 5α-reductase (SRD5A) enzymes.Finasteride users, who reported persistent sexual (...) symptoms after discontinuing finasteride (group 1); age-matched finasteride users who did not report sexual symptoms (group 2); and healthy men who had never used finasteride (group 3).Sexual function, mood, affect, cognition, hormone levels, body composition, functional magnetic resonance imaging (fMRI) response to sexually and affectively valenced stimuli, nucleotide sequences of androgen receptor (AR), SRD5A1, and SRD5A2; expression levels of androgen-dependent genes in skin.Academic medical

2016 Journal of Clinical Endocrinology and Metabolism

80. In silicoprediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss. (Abstract)

In silicoprediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss. Many herbal topical formulations have been marketed worldwide to prevent hair loss or promote hair growth. Certain in vivo studies have shown promising results among them; however, the effectiveness of their bioactive constituents remains unknown.Recently, prostaglandin D2 (PGD2) inhibition has been discovered as a pharmacological mechanism for treating androgenic alopecia (AGA (...) pharmacokinetic properties and minimal adverse skin reactions. These compounds have the highest potential for further in vitro and in vivo investigation with the aim of developing safe and high-efficacy hair loss treatment.Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

2015 Journal of Ethnopharmacology

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