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Androgenic Alopecia

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21. Conventional and novel stem cell based therapies for androgenic alopecia (PubMed)

Conventional and novel stem cell based therapies for androgenic alopecia The prevalence of androgenic alopecia (AGA) increases with age and it affects both men and women. Patients diagnosed with AGA may experience decreased quality of life, depression, and feel self-conscious. There are a variety of therapeutic options ranging from prescription drugs to non-prescription medications. Currently, AGA involves an annual global market revenue of US$4 billion and a growth rate of 1.8%, indicating

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2017 Stem cells and cloning : advances and applications

22. Alopecia

corticosteroids or dithranol, although they are commonly used for the treatment of alopecia areata. Similarly, although 2008 4. Alopecia areata 2017 5. Alopecia , androgenetic - female Alopecia , androgenetic - female - NICE CKS Clinical Knowledge Summaries Share Alopecia , androgenetic - female - Summary Androgenetic alopecia (or female pattern hair loss ) describes a distinctive pattern of hair loss , which may occur in genetically predisposed women and is thought to be androgen dependent. Hair loss (...) , but the rate of progression is unpredictable. Women with androgenetic alopecia rarely go completely bald . The diagnosis is usually made from the history 2016 6. Alopecia , androgenetic - male Alopecia , androgenetic - male - NICE CKS Clinical Knowledge Summaries Share Alopecia , androgenetic - male: Summary Androgenetic alopecia describes a distinctive pattern of hair loss , which may occur in genetically predisposed men and is thought to be androgen dependent. In men, hair loss usually initially involves

2018 Trip Latest and Greatest

23. Alopecia areata multiplex following autologous dermal micro-graft injection for treatment of androgenetic alopecia. (PubMed)

, through genome-wide association studies, gene expression analysis, and a C3H/HeJ mouse model of AA, the cytotoxic subset of CD8+NKG2D+ T cells was revealed to play a major role in AA development 2-4 . In contrast to AA, androgenetic alopecia (AGA) is believed to be caused by androgens on the hair cycles. Among other autologous transplantation procedures, autologous dermal micro-grafts have recently been used to treat AGA 5,6 . Herein, we report a case of AA that developed following an autologous (...) Alopecia areata multiplex following autologous dermal micro-graft injection for treatment of androgenetic alopecia. Alopecia areata (AA) is an autoimmune disease of the hair follicle (HF). Human anagen HFs are protected by immune privilege, defined in part as the absence of MHC class I antigen expression. AA is postulated to occur when the immune-privileged state of the HF is compromised 1 ; however, the immunopathogenesis, including autoantigens, of AA remain incompletely defined. Recently

2019 Journal of the European Academy of Dermatology and Venereology

24. Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia

Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02999737 Recruitment Status : Unknown Verified January 2017 by Amelia K Hausauer, MD, Skin Care

2016 Clinical Trials

25. Pharmacokinetics/ Pharmacodynamics and Safety of DA-4001 in Healthy Male Subjects With Androgenic Alopecia

Pharmacokinetics/ Pharmacodynamics and Safety of DA-4001 in Healthy Male Subjects With Androgenic Alopecia Pharmacokinetics/ Pharmacodynamics and Safety of DA-4001 in Healthy Male Subjects With Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Pharmacokinetics/ Pharmacodynamics and Safety of DA-4001 in Healthy Male Subjects With Androgenic Alopecia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02824380 Recruitment Status : Completed First Posted : July 6, 2016 Last Update Posted

2016 Clinical Trials

26. Are hand preference and sexual orientation possible predicting factors for finasteride adverse effects in male androgenic alopecia? (PubMed)

Are hand preference and sexual orientation possible predicting factors for finasteride adverse effects in male androgenic alopecia? Sexual side effects of finasteride seem to be redoubtable, being encountered not only during therapy but also after treatment cessation. Consequently, any possible clinical/paraclinical elements that might predict these adverse effects would be useful in the selection of a therapeutic strategy for male androgenic alopecia. Previous published studies show that some (...) compounds that interfere with sexual hormones can decrease sexual activation and response, according to hand preference (as reported for finasteride and tamoxifen) and according to sexual orientation (as noted for bicalutamide). Our preliminary published data and the arguments presented here suggest that these two individual parameters might be used by dermatologists in the therapeutic approach of male androgenic alopecia, so as to alert specific subsets of men, prior to treatment, of the potential

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2016 Experimental Dermatology

27. Benign prostatic hyperplasia, metabolic syndrome and androgenic alopecia: Is there a possible relationship? (PubMed)

Benign prostatic hyperplasia, metabolic syndrome and androgenic alopecia: Is there a possible relationship? To evaluate the incidence of benign prostatic hyperplasia (BPH) and metabolic syndrome in patients with androgenetic alopecia (AGA) in comparison with those with no AGA, as several previous studies have reported inconsistent results of an association between metabolic syndrome and BPH with AGA.This cross-sectional study included 400 participants, divided into 300 patients diagnosed

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2016 Arab journal of urology

28. Androgenic Alopecia

Androgenic Alopecia Androgenic Alopecia Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Androgenic Alopecia Androgenic Alopecia Aka (...) : Androgenic Alopecia , Androgenetic Alopecia , Male-patterned Baldness From Related Chapters II. Definition Non-scarring androgen related III. Epidemiology Most common type of (esp. white men) Hereditary trait (positive ) Increasing with age Affects white men 30% at age 30, 40% at age 40, 50% at age 50 years Affects 38% of women over age 70 years IV. Course onset between ages 12 to 40 years evident by age 50 in >50% of patients V. Pathophysiology Androgen exposure shortens phase Men with increased

2018 FP Notebook

29. Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay. (PubMed)

Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay. Androgenic alopecia (AGA) is a major type of human scalp hair loss, which is caused by two androgens: testosterone (T) and 5α-dihydrotestosterone (5α-DHT). Both androgens bind to the androgen receptor (AR) and induce androgen-sensitive genes within the human hair dermal papilla cells (HHDPCs), but 5α-DHT exhibits much higher binding affinity and potency (...) than T does in inducing the involved androgen-sensitive genes. Changes in the induction of androgen-sensitive genes during AGA are caused by the over-production of 5α-DHT by the 5α-reductase (5α-R) enzyme; therefore, one possible method to treat AGA is to inhibit this enzymatic reaction.RT-PCR was used to identify the presence of the 5α-R and AR within HHDPCs. A newly developed AGA-relevant HHDPC-based assay combined with non-radioactive thin layer chromatography (TLC) detection was used

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2016 BMC Complementary and Alternative Medicine

30. Finasteride adverse effects in subjects with androgenic alopecia: A possible therapeutic approach according to the lateralization process of the brain. (PubMed)

Finasteride adverse effects in subjects with androgenic alopecia: A possible therapeutic approach according to the lateralization process of the brain. Nowadays, finasteride is a relatively frequently prescribed drug in the therapeutic management of male androgenic alopecia. The reported adverse effects are notable in some patients, consisting in signs and symptoms that are encountered both during finasteride administration and after treatment cessation. Clinical and imagistic data show (...) in dermatological practice, and to highlight its relevance in respect to therapeutic approach of male androgenic alopecia. As a possible therapeutic application, subjects having preference for a certain sexual orientation and/or predisposition for a given dominant hand could be advised before finasteride administration, that present an increased risk/sensitivity to develop adverse effects. Finally, even if finasteride and post-finasteride symptoms overlap to a large extent they should be, however, viewed

2016 Journal of Dermatological Treatment

31. Efficacy and safety of traditional Chinese medicine for refractory androgenic alopecia: a meta-analysis of randomized controlled trials

Efficacy and safety of traditional Chinese medicine for refractory androgenic alopecia: a meta-analysis of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2019 PROSPERO

32. FEMALE PATTERN HAIR LOSS AND ANDROGEN EXCESS: A REPORT FROM THE MULTIDISCIPLINARY ANDROGEN EXCESS AND PCOS COMMITTEE. (PubMed)

terms of alopecia or androgenetic alopecia. 2.The two typical patterns of hair loss in FPHL are centrifugal expansion in mid scalp or a frontal accentuation or Christmas tree pattern. 3. Isolated FPHL should not be considered a sign of hyperandrogenism when androgen levels are normal 4. The assessment of patients with FPHL is primarily clinical. 5. In all patients with FPHL, assessment of a possible androgen excess is mandatory. Measurement of vitamin D, iron studies, zinc, thyroid hormones (...) FEMALE PATTERN HAIR LOSS AND ANDROGEN EXCESS: A REPORT FROM THE MULTIDISCIPLINARY ANDROGEN EXCESS AND PCOS COMMITTEE. To determine the current state of knowledge and provide evidence-based recommendations that could be valid for all specialists taking care of female pattern hair loss (FPHL), a common form of hair loss in women that is characterized by the reduction of hair density in the central area of the scalp, while the frontal hairline is generally well conserved.An expert task force

2019 Journal of Clinical Endocrinology and Metabolism

33. The diagnosis of androgenetic alopecia in children: Considerations of pathophysiological plausibility. (PubMed)

The diagnosis of androgenetic alopecia in children: Considerations of pathophysiological plausibility. Androgenetic alopecia (AGA), one of the most common causes of hair loss in men and women, is an infrequent cause of alopecia in children. In AGA, patients generally start noticing hair thinning after the onset of puberty due to progressive miniaturisation of the hair follicle which leads to vellus transformation of terminal hair. However, the occurrence of prepubertal AGA has rarely been (...) reported in the literature. The pathophysiology of AGA is tightly linked to androgen hormones; prepubertal children do not usually produce significant amounts of adrenal or gonadal androgens. When it does occur, an underlying abnormality should be suspected. Secondary causes of AGA must be excluded when evaluating a patient before the appearance of puberty. Premature puberty, polycystic ovarian syndrome and other causes of hyperandrogenism can present with hair loss in an androgenetic pattern

2019 Australasian Journal of Dermatology

34. The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia

The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02594046 Recruitment Status : Completed First Posted : November 2, 2015 Last Update Posted : April 5, 2017

2015 Clinical Trials

35. Minimally invasive treatment in female androgen alopecia: a systematic review

Minimally invasive treatment in female androgen alopecia: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing and effect

2018 PROSPERO

36. Minoxidil 2% Solution and Botanical Hair Regimen in Women With Thinning Hair and Female Pattern Hair Loss/Androgenic Alopecia

Minoxidil 2% Solution and Botanical Hair Regimen in Women With Thinning Hair and Female Pattern Hair Loss/Androgenic Alopecia Minoxidil 2% Solution and Botanical Hair Regimen in Women With Thinning Hair and Female Pattern Hair Loss/Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Minoxidil 2% Solution and Botanical Hair Regimen in Women With Thinning Hair and Female Pattern Hair Loss/Androgenic Alopecia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02460497 Recruitment Status

2015 Clinical Trials

37. Minoxidil 5% / Botanical Hair Regimen in Men With Thinning Hair and Male Pattern Hair Loss/Androgenic Alopecia

Minoxidil 5% / Botanical Hair Regimen in Men With Thinning Hair and Male Pattern Hair Loss/Androgenic Alopecia Minoxidil 5% / Botanical Hair Regimen in Men With Thinning Hair and Male Pattern Hair Loss/Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Minoxidil 5% / Botanical Hair Regimen in Men With Thinning Hair and Male Pattern Hair Loss/Androgenic Alopecia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02460289 Recruitment Status : Completed First Posted : June 2, 2015 Last

2015 Clinical Trials

38. Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial. (PubMed)

Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial. We conducted a 16-week double-blind randomized controlled single-center trial to evaluate the safety and efficacy of dermal rice bran supercritical CO2 extract (RB-SCE) in the treatment of androgenic alopecia. Fifty alopecia patients were randomly assigned to the experimental and placebo groups. The experimental group received a dermal (...) confirmed the effectiveness of RB-SCE in the treatment of alopecia. No adverse reactions related to RB-SCE were reported. Therefore, RB-SCE shows promise for use in functional cosmetics and pharmaceuticals.

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2015 Biological & pharmaceutical bulletin

39. Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. (PubMed)

Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. Both androgenetic alopecia (AGA) and carcinoma of the prostate (CaP) or benign prostatic hyperplasia (BPH) are androgen-dependent disorders.To investigate the relationships between male androgenetic alopecia, androgen receptor (AR) gene polymorphism (SNP rs6152) and clinical characteristics of BPH and prostate cancer.Overall, 309 male subjects (...) and between anagen/telogen and AGA were found. A statistically significant difference between patients with A and G alleles in terms of AGA grade was found. The predominant G allele was more frequent in patients with higher grade of alopecia and in patients with significantly higher PSA. There was no correlation between diagnosis (BPH or CaP) and polymorphism. Patients with prostate inflammation had a statistically significant higher grade of AGA, together with higher PSA.We confirmed that the AR gene

2015 Journal of the European Academy of Dermatology and Venereology

40. Hair micro transplant using follicular unit extraction technique for alopecia

. Noviembre de 2015. Authors' conclusions Scarce evidence of low methodological quality was found, assessing the follicular unit extraction technique in hair micro transplant with aesthetic purposes in androgen-related alopecia and other indications. The studies identified do not show relevant benefits. No randomized clinical trials have been identified, and there are no studies comparing this surgical technique with the standard medical treatment for alopecia. This technique is not considered (...) Hair micro transplant using follicular unit extraction technique for alopecia Hair micro transplant using follicular unit extraction technique for alopecia Hair micro transplant using follicular unit extraction technique for alopecia Macchiavello D, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L., Hernandez Vásquez A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA

2015 Health Technology Assessment (HTA) Database.

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