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Androgenic Alopecia

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21. Hair Graft Transplantation for Baldness

and categorizes the typical sequence of the hair loss process in men. [ ] Early in the process (types 1-3), the hairline recedes, typically led by frontotemporal recessions. In the latter stages (types 4-7), progression of hair loss at the vertex (crown) gradually meets and joins the progressive hairline recession, resulting in varying sizes (in both coronal and sagittal dimensions) of the confluent vertex with frontotemporal regions of baldness. For women, the development of androgenic alopecia is classified (...) inflammatory contribution to hair loss, as scalp biopsies often reveal a localization of lymphocytic folliculitis around the stem-cell–containing bulge region of the hair follicle. [ ] As with male pattern baldness, female pattern androgenic hair loss is progressive. Alopecia areata is an autoimmune hair cycle shift that can be present in any area of the scalp, including donor areas, so that all scalp hairs may be involved, leaving no healthy donor follicles. It also resolves with medication and topical

2014 eMedicine Surgery

22. Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma (PRP) for Treating Androgenic Alopecia. (Abstract)

Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma (PRP) for Treating Androgenic Alopecia. Androgenetic alopecia (AGA), the most common cause of hair loss in both sexes, accounts for 95% of all cases of hair loss. Although the literature has suggested that both nonactivated (n-PRP) and activated autologous (a-PRP) PRP can be used to treat AGA, we did not find any study investigating the use of homologous PRP (h-PRP) for this purpose. Also, to the best of our knowledge (...) , there are no studies comparing the efficacy of h-PRP, a-PRP, or n-PRP on AGA therapy.The aim of this study was to compare the increase in hair density, average number of platelets, complications, preparation, and duration of application in the treatment of AGA using a-PRP, n-PRP, and h-PRP.Between 2014 and 2015, we studied male patients who had experienced increased hair loss in the last year. Patients were divided into three groups: Group 1 received n-PRP, Group 2 received active PRP, and Group 3 received h-PRP

2018 Aesthetic plastic surgery

23. A Comparative Study between the Efficacy and Safety of 5% Minoxidil Solution and 5% Minoxidil Milky Lotion in the Treatment of Male Androgenic Alopecia. (Abstract)

A Comparative Study between the Efficacy and Safety of 5% Minoxidil Solution and 5% Minoxidil Milky Lotion in the Treatment of Male Androgenic Alopecia. 5% minoxidil solution is approved for the treatment of male androgenetic alopecia (AGA). However, there have been occasional reports of adverse events that were caused mostly by propylene glycol sensitivity. As an alternative treatment, Siriraj hair team developed a proprietary preparation referred to as “minoxidil milky lotion” that uses (...) butylene glycol as a substitute for propylene glycol.To compare the efficacy and safety of 5% minoxidil solution with 5% minoxidil milky lotion in the treatment of male AGA.Twenty males with AGA were recruited for this prospective randomized study. Subjects were randomly treated with 5% minoxidil solution or 5% minoxidil milky lotion. Clinical outcomes and adverse events were recorded at 8, 16, and 24 weeks.The mean age of subjects was 43.5±12.5 years (range, 26-65 years). Percentage increase in hair

2018 Journal of the Medical Association of Thailand = Chotmaihet thangphaet Controlled trial quality: uncertain

24. Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women

Information provided by (Responsible Party): Alison J. Bruce, Mayo Clinic Study Details Study Description Go to Brief Summary: The primary objective of this proposal is to conduct a study that assesses the safety, feasibility and efficacy of using PRP to treat this type of hair loss. Condition or disease Intervention/treatment Phase Alopecia Other: Platelet Rich Plasma Drug: Minoxidil Foam Phase 1 Phase 2 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial (...) Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2018 Clinical Trials

25. The Effect of Microneedling With Low Energy Laser in Androgenic Alopecia Patients.

, temporal scalp, and vertex of the scalp are typical sites of involvement. "Male balding" and "male pattern hair loss" are additional terms used to refer to this condition. The aim of this study is to investigate the effect of microneedling in androgenic alopecia Condition or disease Intervention/treatment Phase Dermatologic Disease Device: accupuncture Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 30 participants (...) Update Posted : October 29, 2018 See Sponsor: Shin Kong Wu Ho-Su Memorial Hospital Information provided by (Responsible Party): Shin Kong Wu Ho-Su Memorial Hospital Study Details Study Description Go to Brief Summary: Androgenetic alopecia is the most common type of hair loss in men, and affects approximately 50 percent of Caucasian men by age 50. The condition is characterized by the progressive loss of terminal hairs on the scalp in a characteristic distribution. The anterior scalp, mid scalp

2018 Clinical Trials

26. Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia

Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03676400 Recruitment Status : Recruiting First Posted : September 18, 2018 Last Update Posted

2018 Clinical Trials

27. Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia

recruiting First Posted : March 22, 2018 Last Update Posted : March 11, 2019 See Sponsor: Wake Forest University Health Sciences Information provided by (Responsible Party): Wake Forest University Health Sciences Study Details Study Description Go to Brief Summary: The study team will assess the efficacy of platelet-rich plasma therapy, a special blood product which is from the participant's own body, in the treatment of androgenic alopecia (also known as male pattern hair loss) in females. Condition (...) or disease Intervention/treatment Phase Androgenic Alopecia Biological: Platelet-rich Plasma Left Side Biological: Platelet-rich Plasma Right Side Early Phase 1 Detailed Description: Androgenic alopecia, or male-pattern hair loss affects both men and women. This hair loss pattern is typically characterized by thinning at the crown of scalp and/or M-shaped hair line in males or diffuse thinning throughout in females. Platelet-rich plasma (PRP) therapy has recently been studied as a hair rejuvenation

2018 Clinical Trials

28. Relationship of early-onset baldness to prostate cancer in african-american men. Full Text available with Trip Pro

+.) Associations of androgen metabolism genotypes (CYP3A4, CYP3A5, CYP3A43, AR-CAG, SRD5A2 A49T, and SRD5A2 V89L), family history, alcohol intake, and smoking were examined by baldness status and age group by using multivariable logistic regression models.Baldness was associated with odds of prostate cancer [OR = 1.69; 95% confidence interval (CI), 1.05-2.74]. Frontal baldness was associated with high-stage (OR = 2.61; 95% CI, 1.10-6.18) and high-grade (OR = 2.20; 95% CI, 1.05-4.61) tumors. For men diagnosed (...) Relationship of early-onset baldness to prostate cancer in african-american men. Early-onset baldness has been linked to prostate cancer; however, little is known about this relationship in African-Americans who are at elevated prostate cancer risk.We recruited 219 African-American controls and 318 African-American prostate cancer cases. We determined age-stratified associations of baldness with prostate cancer occurrence and severity defined by high stage (T3/T4) or high grade (Gleason 7

2013 Cancer Epidemiology & Biomarkers and Prevention

29. 24 Week Clinical Trial to Evaluate Safety and Effectiveness of a Hair Growth System to Treat Male and Female Baldness

: September 18, 2012 Last Update Posted: September 18, 2012 Last Verified: September 2012 Keywords provided by Freedom Laser Therapy, Inc.: androgenetic alopecia Baldness Additional relevant MeSH terms: Layout table for MeSH terms Alopecia Alopecia Areata Hypotrichosis Hair Diseases Skin Diseases Pathological Conditions, Anatomical (...) 24 Week Clinical Trial to Evaluate Safety and Effectiveness of a Hair Growth System to Treat Male and Female Baldness 24 Week Clinical Trial to Evaluate Safety and Effectiveness of a Hair Growth System to Treat Male and Female Baldness - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2012 Clinical Trials

30. Alopecia

, but the rate of progression is unpredictable. Women with androgenetic alopecia rarely go completely bald . The diagnosis is usually made from the history 2016 6. Alopecia , androgenetic - male Alopecia , androgenetic - male - NICE CKS Clinical Knowledge Summaries Share Alopecia , androgenetic - male: Summary Androgenetic alopecia describes a distinctive pattern of hair loss , which may occur in genetically predisposed men and is thought to be androgen dependent. In men, hair loss usually initially involves (...) , producing circular areas of loss. Total loss of scalp hair ( alopecia totalis) or scalp (...) and body hair ( alopecia universalis) occurs less commonly. The exact cause of alopecia areata is unknown. Alopecia areata is a relatively common condition. It has been estimated that it affects 15 people in 10,000 of the UK population. It can present at any age but 60% of people develop their first bald patch before 20 years of age. The progress of alopecia areata is unpredictable. Patchy alopecia areata

2018 Trip Latest and Greatest

31. Distribution of polyamines may be altered in different scalp regions of patients with hair loss. Full Text available with Trip Pro

Distribution of polyamines may be altered in different scalp regions of patients with hair loss. Hair loss, from the vertex or front of the head, generally occurs due to increased androgenic steroid levels. Androgenic steroids, particularly testosterone and dihydrotestosterone, are distributed differently across the vertex and occipital regions, and are involved in inducing ornithine decarboxylase expression. Therefore, we hypothesized that the distribution of polyamines may be altered (...) in different scalp regions. For the overall metabolic profiling of polyamines in patients with hair loss, a liquid chromatography-mass spectrometry was used. We investigated the differential polyamine levels in different regions of the hair of patients with male-pattern baldness and those with female-pattern hair loss. The levels of most polyamines were higher in the vertex region than in the occipital region, and N-acetyl polyamine levels differed significantly. We proposed to test our hypothesis

2019 Experimental Dermatology

32. The role of photobiomodulation when associated with microneedling in female pattern hair loss: A randomized, double blind, parallel group, three arm, clinical study protocol. Full Text available with Trip Pro

that photobiomodulation is a safe and effective way to treat the different types of hair loss. It was also known that microneedling is a minimally invasive dermatological procedure that is applied to a wide range of dermatological conditions, including androgenic alopecia, telogen effluvium, as well as other facial and bodily conditions.The aim of this study is to verify if there is an increase in the capillary density of strands of hair, when combining 660 nm red laser photobiomodulation and microneedling (...) The role of photobiomodulation when associated with microneedling in female pattern hair loss: A randomized, double blind, parallel group, three arm, clinical study protocol. The female hair loss pattern was originally described as a synonym for androgenetic alopecia. It has been defined as progressive miniaturizations of the hair follicles, with a great impact on the quality of life of affected patients, causing significant psychosocial limitations. It was recently proven

2019 Medicine Controlled trial quality: uncertain

33. Comparison of the effects of 665 nm low level diode Laser Hat versus and a combination of 665 nm and 808nm low level diode Laser Scanner of hair growth in androgenic alopecia. (Abstract)

Comparison of the effects of 665 nm low level diode Laser Hat versus and a combination of 665 nm and 808nm low level diode Laser Scanner of hair growth in androgenic alopecia. This study aimed to evaluate the effectiveness of a combined set of low level diode laser scanner (665 nm and 808nm) on hair growth, and assessment of safety and effectiveness of a new laser scanner on hair growth treatment procedure in androgenic alopecia.90 patients (18 to 70 years) with androgenic alopecia were (...) randomized into three groups. The first group (n=30) received 655 nm red light using laser hat, the second group (n=30) received 655 nm red laser plus 808 nm infrared laser using a laser scanner of hair growth device (with the patent number: 77733) and the third group (n=30) received no laser as the control group.Patients in laser scanner group had better results and showed a higher increase in terminal hair density compared with laser hat group (mean of 9.61 versus 9.16 per cm2). We found significant

2017 Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology Controlled trial quality: uncertain

34. Hematuria and Hematospermia Associated with the Use of Finasteride for the Treatment of Androgenic Alopecia: A Case Report Full Text available with Trip Pro

Hematuria and Hematospermia Associated with the Use of Finasteride for the Treatment of Androgenic Alopecia: A Case Report In this report we address an unusual adverse effect of finasteride (Propecia 1 mg tablets) that was associated with painless hematuria and hematospermia in a 38-year-old healthy male during treatment of androgenic alopecia at a dose of 1 mg/day. It was found that the bleeding was linked to finasteride use as it occurred 2-3 days after use and stopped upon discontinuation

2017 Drug Safety - Case Reports

35. Conventional and novel stem cell based therapies for androgenic alopecia Full Text available with Trip Pro

Conventional and novel stem cell based therapies for androgenic alopecia The prevalence of androgenic alopecia (AGA) increases with age and it affects both men and women. Patients diagnosed with AGA may experience decreased quality of life, depression, and feel self-conscious. There are a variety of therapeutic options ranging from prescription drugs to non-prescription medications. Currently, AGA involves an annual global market revenue of US$4 billion and a growth rate of 1.8%, indicating (...) a growing consumer market. Although natural and synthetic ingredients can promote hair growth and, therefore, be useful to treat AGA, some of them have important adverse effects and unknown mechanisms of action that limit their use and benefits. Biologic factors that include signaling from stem cells, dermal papilla cells, and platelet-rich plasma are some of the current therapeutic agents being studied for hair restoration with milder side effects. However, most of the mechanisms exerted

2017 Stem cells and cloning : advances and applications

36. Efficacy and safety of traditional Chinese medicine for refractory androgenic alopecia: a meta-analysis of randomized controlled trials

Efficacy and safety of traditional Chinese medicine for refractory androgenic alopecia: a meta-analysis of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2019 PROSPERO

37. Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population. Full Text available with Trip Pro

Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population. To investigate the association of CAG repeat numbers in the androgen receptor (AR) gene with female pattern hair loss (FPHL) in a Chinese population.A total of 200 Han Chinese patients with FPHL (142 Ludwig II and 58 Ludwig III cases) and 200 healthy controls were enrolled in this study. The polymorphism of CAG repeat numbers was analyzed by the fluorescent amplified fragment

2016 Dermatology

38. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study. (Abstract)

Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study. The relationship between female pattern hair loss (FPHL) and androgenic hormones is not well established, but some evidence indicates oral finasteride may be efficacious in FPHL. Use of a topical formulation has been proposed to minimize unwanted effects.Our objective was to compare the efficacy and safety of topical 0.25 (...) % finasteride combined with 3% minoxidil solution and 3% minoxidil solution as monotherapy in the treatment of FPHL.This was a prospective, randomized, double-blind study in 30 postmenopausal women with FPHL. Each participant was randomized to receive either topical 0.25% finasteride combined with topical 3% minoxidil or topical 3% minoxidil solution as monotherapy for 24 weeks. To determine efficacy, the hair density and diameter was measured and global photographic assessment was conducted at baseline

2018 American journal of clinical dermatology Controlled trial quality: predicted high

39. Oral Nutraceutical Supplement With Standardized Botanicals in Males With Self-Perceived Thinning Hair and Loss

agreement approved by the Institutional Review Board. Be able to complete and understand the various rating instruments in English. Exclusion Criteria: Clinical diagnosis of alopecia areata or scarring forms of alopecia Scalp hair loss on the treatment area, due to disease, injury, or medical therapy Current skin disease (e.g., psoriasis, atopic dermatitis, skin cancer, eczema, sun damage, seborrheic dermatitis), cuts and or abrasions on the scalp or condition (e.g., sunburn, tattoos) on the treatment (...) area that, in the opinion of the Investigator, might put the subject at risk or interfere with the study conduct or evaluations. History of surgical correction of hair loss on the scalp (i.e. Hair transplant). Use of any products or devices purported to promote scalp hair growth (e.g., finasteride or minoxidil) within the 6 months prior to the Baseline Visit. Use of anti-androgenic therapies (e.g., spironolactone, flutamide, cyproterone acetate, progesterone, and bicalutamide) within 3 months prior

2018 Clinical Trials

40. Efficacy and Safety Study to Compare Topical Herbal Solution and Minoxidil 5% in Male Pattern Hair Loss

2019 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Farid Masoud, Tabriz University of Medical Sciences: Androgenic Alopecia Hair Diseases Skin Diseases Baldness Alopecia Hair Loss Additional relevant MeSH terms: Layout table for MeSH terms Alopecia Alopecia Areata Hypotrichosis Hair Diseases Skin Diseases (...) Efficacy and Safety Study to Compare Topical Herbal Solution and Minoxidil 5% in Male Pattern Hair Loss Efficacy and Safety Study to Compare Topical Herbal Solution and Minoxidil 5% in Male Pattern Hair Loss - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2018 Clinical Trials

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