How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

12,104 results for

Anaphylaxis

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

61. Advances in Drug Allergy, Urticaria, Angioedema and Anaphylaxis in 2018. (Abstract)

Advances in Drug Allergy, Urticaria, Angioedema and Anaphylaxis in 2018. Many notable advances in drug allergy, urticaria, angioedema and anaphylaxis were reported in 2018. Broad spectrum antibiotic use and consequently antibiotic resistance is widespread, and algorithms to clarify β-lactam allergy and optimize antibiotic use were described. Meaningful data emerged on the pathogenesis of delayed drug hypersensitivity reactions. Progress not only in defining biomarkers, but also in understanding (...) and triggers of anaphylaxis, and the mechanisms underlying anaphylaxis, were elucidated further. In summary, these disorders (and labels) cause substantial burdens for individuals and even society. Fortunately, publications in 2018 have informed on advancements in diagnosis and management and have provided better understanding of mechanisms that potentially could yield new therapies. This progress should lead to better health outcomes and paths forward in drug allergy, urticaria, hereditary angioedema

2019 Journal of Allergy and Clinical Immunology

62. Food allergy endotype with high risk of severe anaphylaxis in children-Monosensitization to cashew 2S albumin Ana o 3. (Abstract)

Food allergy endotype with high risk of severe anaphylaxis in children-Monosensitization to cashew 2S albumin Ana o 3. Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated risks, among children in a large, population-based setting.Two hundred (...) and seventy-one children who were hospitalized due to systemic allergic reaction (SAR) and food anaphylaxis were recruited. Medical history was assessed, and culprit allergen source and anaphylaxis severity grade were established. Specific IgE to 112 allergen components using multiplex ImmunoCAP ISAC immunoassay and specific IgE to hazelnut, Cor a 14, and cashew, Ana o 3, using singleplex ImmunoCAP immunoassay were determined.We analyzed data from 237 SAR/anaphylaxis in 237 children. Trigger at allergen

2019 Allergy

63. Contact urticaria (CU): frequency, elicitors and cofactors in three cohorts (Information Network of Departments of Dermatology (IVDK); Network of Anaphylaxis and Dept. of Dermatology University Hospital Erlangen, Germany). Full Text available with Trip Pro

Contact urticaria (CU): frequency, elicitors and cofactors in three cohorts (Information Network of Departments of Dermatology (IVDK); Network of Anaphylaxis and Dept. of Dermatology University Hospital Erlangen, Germany). Contact urticaria (CU) is an infrequent, mostly occupational disease that may be life-threatening (CU syndrome stage 4).To identify the current frequency, elicitors and cofactors of CU.Three cohorts were retrospectively analysed for CU: (a) patients from the Information (...) Network of Departments of Dermatology (IVDK) database (2000-2014; n = 159 947); (b) patients from an allergy unit (Department of Dermatology, University Hospital Erlangen, 2000-2015; n = 4741); and (c) patients from the Anaphylaxis Registry (2007-2015: 6365 reported cases, including 2473 patients with Ring and Messmer grade III-IV reactions) for severe cases with skin/mucosal manifestations occurring at the workplace vs cases not occurring at the workplace (n = 68 vs n = 1821).Four hundred and forty

2019 Contact Dermatitis

64. Idiopathic anaphylaxis. (Abstract)

Idiopathic anaphylaxis. Idiopathic anaphylaxis (IA) or spontaneous anaphylaxis is a diagnosis of exclusion when no cause can be identified. The exact incidence and prevalence of IA is not known. The clinical manifestations of IA are similar to other known causes of anaphylaxis. A typical attack is usually acute in onset and can worsen over minutes to a few hours. The pathophysiology of IA has not yet been fully elucidated, although an IgE-mediated pathway by hitherto unidentified trigger/s (...) , pigeon tick bite (Argax reflexus), pine processionary caterpillar allergy, wheat-dependent exercise-induced anaphylaxis, Anisakis simplex allergy and mast cell disorders. Other differential diagnoses include 'allergy-mimics' such as asthma masquerading as anaphylaxis, undifferentiated somatoform disorder, panic attacks, globus hystericus, vocal cord dysfunction, scombroid poisoning, vasoactive amine intolerance, carcinoid syndrome and phaeochromocytoma. Acute treatment of IA is the same as for other

2019 Clinical and Experimental Allergy

65. Pre-hospital management of pediatric anaphylaxis by French Emergency Medicine physicians: still to be improved. (Abstract)

Pre-hospital management of pediatric anaphylaxis by French Emergency Medicine physicians: still to be improved. Food allergy (FA), is the main cause of anaphylaxis in children (1). Early recognition and treatment are crucial to avoid a rapid progression into a life-threatening condition. Several anaphylaxis guidelines have been published, including those issued by the Resuscitation Council (2008), the World Health Organization (2011), the European Academy of Allergy and Clinical Immunology

2019 Clinical and Experimental Allergy

66. 'It's not an illness, it's just bad luck': The impact of anaphylaxis on quality of life in adults. Full Text available with Trip Pro

'It's not an illness, it's just bad luck': The impact of anaphylaxis on quality of life in adults. An increasing number of adults are being diagnosed with anaphylaxis, but its impact on health-related quality of life (HRQol) is not known.The aim of this study was to explore the impact of anaphylaxis on HRQoL of newly diagnosed adults.Interviews were conducted with 13 adults (aged 40-71; 5 males) with anaphylaxis (meeting WAO diagnostic criteria) to drugs, food, venom or spontaneous anaphylaxis (...) , recruited using purposive sampling from allergy clinics in Birmingham, UK. Data was transcribed verbatim and analysed using thematic analysis.Four themes were generated from the analysis: the journey from fear to frustration; the need to maintain a healthy identity; control over uncertainty; and the supportive role of others. Participants described their first experiences of anaphylaxis as frightening. Managing the condition was associated with frustration and anxiety, in part due to uncertainty

2019 Clinical and Experimental Allergy

67. Food dependent exercise induced anaphylaxis triggered by inhaled antigen. (Abstract)

Food dependent exercise induced anaphylaxis triggered by inhaled antigen. We present a unique case of food dependent exercise induced anaphylaxis (FDEIA) triggered by an inhaled allergen in a 23- year-old professional cyclist. FDEIA is considered a rare form of anaphylaxis in which the state of exercise can trigger mast cell degranulation to an allergen which normally does not cause a reaction. It is closely related to exercise induced anaphylaxis, which occurs with exercise but in the absence (...) of a food trigger. The patient experienced an anaphylactic reaction during a bicycle race when the race went through an almond orchard in full bloom. He was successfully stabilized with aggressive measures including steroids, fluids, anti-histamines and multiple doses of epinephrine.Copyright © 2019 Elsevier Inc. All rights reserved.

2019 American Journal of Emergency Medicine

68. Trends in hospitalizations related to anaphylaxis, angioedema, and urticaria in the United States. (Abstract)

Trends in hospitalizations related to anaphylaxis, angioedema, and urticaria in the United States. Data on the prevalence of allergic disorders over time are limited. Recent studies have noted marked increase in the prevalence of allergic conditions in different parts of the world.To examine time trends in the prevalence of anaphylaxis, angioedema, and urticaria in the United States.Using the largest inpatient National Inpatient Sample data in the United States from 2001 to 2014, adults (...) admitted with a primary diagnosis of anaphylaxis, angioedema, or urticaria were identified based on International Classification of Diseases, Ninth Revision codes. Yearly distribution of hospital admissions was stratified per different age groups, and yearly trends of hospitalizations related to anaphylaxis, angioedema, and urticaria were calculated.Although an increasing trend in the rate of hospitalizations was seen for angioedema (annual percentage change [APC], 4.48), a decreasing trend (APC, -2.19

2019 Asthma & Immunology

69. Factors predicting anaphylaxis in children with tree nut allergies. (Abstract)

Factors predicting anaphylaxis in children with tree nut allergies. Background: Tree nut (TN) allergies are the most common cause of fatal anaphylaxis and generally are ongoing food allergies throughout life. Objective: To investigate the predicting factors for TN anaphylaxis in children. Methods: Children with TN allergy were divided into anaphylactic and nonanaphylactic groups, those who had an anaphylactic reaction with at least one type of TN and those with any type of reaction other than (...) anaphylaxis with TNs, respectively. Children with TN allergies were evaluated for the predictors of anaphylaxis by using multivariate logistic regression analysis. Results: A total of 184 children (ages 4.9 years; 3.2-6.9 years) with TN allergy were included in the study. Of these, 90 experienced an anaphylactic type of reaction on exposure to at least one type of TNs. Comparisons of the two groups showed that concomitant asthma, skin-prick test, specific immunoglobulin E, total immunoglobulin E

2019 Allergy and Asthma Proceedings

70. Ingestion of Casein Hydrolysate Induces Oral Tolerance and Suppresses Subsequent Epicutaneous Sensitization and Development of Anaphylaxis Reaction to Casein in Mice. (Abstract)

Ingestion of Casein Hydrolysate Induces Oral Tolerance and Suppresses Subsequent Epicutaneous Sensitization and Development of Anaphylaxis Reaction to Casein in Mice. Casein is the most dominant causal allergen in cow's milk allergy (CMA). Casein hydrolysates are frequently applied in infant formulas for children with a risk or history of CMA. However, there is limited information on the oral tolerance-inducing ability of casein hydrolysates.The aim of this study was to investigate whether (...) the ingestion of casein hydrolysate induces tolerance to casein, ultimately preventing subsequent epicutaneous sensitization and development of an anaphylaxis reaction.BALB/c mice were orally administered casein or a casein hydrolysate (CNH) via the drinking water and were then epicutaneously sensitized by repeated exposure of casein on tape-stripped skin. Sensitization was assessed by basophil activation tests, the serum levels of casein-specific antibodies, and cytokine production from casein-stimulated

2019 International Archives of Allergy and Immunology

71. Anaphylaxis after Elosulfase A infusion: Omalizumab as coadyuvant for enzyme replacement therapy desensitization. (Abstract)

Anaphylaxis after Elosulfase A infusion: Omalizumab as coadyuvant for enzyme replacement therapy desensitization. Type IV A Mucopolysaccharidosis (MPS IV A) is a lysosomal storage disease caused by an autosomal recessive mutation in the gene encoding the enzyme galactosamine-6-sulfatase, which catalyses the degradation of glycosaminoglycans (GAGs). It leads to the accumulation of GAGs keratan sulfate. Symptoms include skeletal dysplasia, atlantoaxial instability, pectus carinatum, short stature

2019 Pediatric Allergy and Immunology

72. Common causes of emergency department visits for anaphylaxis in Korean community hospitals: A cross-sectional study. Full Text available with Trip Pro

Common causes of emergency department visits for anaphylaxis in Korean community hospitals: A cross-sectional study. Anaphylaxis can cause death and requires immediate management. For prevention and education programs for anaphylaxis, it is important to be aware of the common triggering factors. We investigated the triggers of anaphylaxis in the emergency departments (EDs) of community hospitals in Korea.Patients who visited the EDs of 7 community hospitals for anaphylaxis from January 1, 2012 (...) to December 31, 2016 were enrolled. Anaphylaxis was defined according to the World Allergy Organization criteria and identified via a thorough review of the medical records of patients who were diagnosed with anaphylaxis (ICD-10 codes: T780, T782, T805, and T886) at the ED or administered epinephrine in the ED. Triggers of anaphylaxis were also evaluated by a review of the medical records.We identified 1021 ED visits for anaphylaxis. The incidence of anaphylaxis ED visits was 0.08%. The triggers of ED

2019 Medicine

73. Duration of Observation for Detecting a Biphasic Reaction in Anaphylaxis: A Meta-Analysis. (Abstract)

Duration of Observation for Detecting a Biphasic Reaction in Anaphylaxis: A Meta-Analysis. We conducted a meta-analysis to determine a practical observation time for detecting a biphasic reaction after resolution of the initial anaphylactic reaction.A systematic literature search identified studies on adult patients with anaphylaxis and a subsequent biphasic reaction due to various causes that contained sufficient data to extract outcomes. The outcomes were pooled using a random-effects (...) model.Twelve studies with a total of 2,890 adult patients with anaphylaxis and 143 patients with a biphasic reaction were included. In terms of the pooled negative predictive value, 1 h of observation achieved a 95.0% negative predictive value and ≥6 h of observation provided a 97.3% negative predictive value (95% CI: 95.0-98.5). The negative predictive value for a biphasic reaction increased with a longer observation time after initial anaphylaxis, and the increasing trend slowed down from 6 h

2019 International Archives of Allergy and Immunology

74. Epinephrine Administered for Anaphylaxis Unmasking a Type 1 Brugada Pattern on Electrocardiogram. (Abstract)

Epinephrine Administered for Anaphylaxis Unmasking a Type 1 Brugada Pattern on Electrocardiogram. Brugada pattern on electrocardiography (ECG) can manifest as type 1 (coved pattern) and type 2 (saddleback pattern). Brugada syndrome represents an ECG with Brugada pattern in a patient with symptoms or clinical factors, including syncope, cardiac arrest, ventricular dysrhythmias, and family history. Brugada syndrome is caused by a genetic channelopathy, but the Brugada pattern may be drug-induced (...) . Epinephrine-induced Brugada pattern has not been reported previously.A 63-year-old man developed anaphylaxis secondary to a bee sting, had a transient loss of consciousness, and self-administered intramuscular epinephrine. He subsequently presented to the emergency department and was found to have a type 1 Brugada pattern on ECG that resolved during observation. A historic ECG was reviewed that demonstrated a baseline type 2 Brugada pattern. His anaphylaxis was managed with steroids and antihistamines. He

2019 Journal of Emergency Medicine

75. Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community. Full Text available with Trip Pro

Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community. Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may cause death. Adrenaline (epinephrine) auto-injectors are recommended as the initial, potentially life-saving treatment of choice for anaphylaxis in the community, but they are not universally available and have limitations in their use.To assess the effectiveness of adrenaline (epinephrine) auto (...) -injectors in relieving respiratory, cardiovascular, and other symptoms during episodes of anaphylaxis that occur in the community.We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 1), MEDLINE (Ovid SP) (1950 to January 2012), EMBASE (Ovid SP) (1980 to January 2012 ), CINAHL (EBSCO host) (1982 to January 2012 ), AMED (EBSCO host) (1985 to January 2012 ), LILACS, (BIREME) (1980 to January 2012 ), ISI Web of Science (1950 to January 2012 ). We

2012 Cochrane

76. Glucocorticoids for the treatment of anaphylaxis. Full Text available with Trip Pro

Glucocorticoids for the treatment of anaphylaxis. Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may result in death. Anaphylaxis guidelines recommend glucocorticoids for the treatment of people experiencing anaphylaxis.We sought to assess the benefits and harms of glucocorticoid treatment during episodes of anaphylaxis.In our previous version we searched the literature until September 2009. In this version we searched the Cochrane Central Register of Controlled (...) Trials (CENTRAL) (The Cochrane Library 2011, Issue 3), MEDLINE (Ovid) (1956 to September 2011), EMBASE (Ovid) (1982 to September 2011), CINAHL (EBSCOhost) (to September 2011). We also searched the UK National Research Register and websites listing ongoing trials, and contacted international experts in anaphylaxis in an attempt to locate unpublished material.We planned to include randomized and quasi-randomized controlled trials comparing glucocorticoids with any control (either placebo, adrenaline

2012 Cochrane

77. Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines

Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines TITLE: Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines DATE: 30 October 2013 RESEARCH QUESTIONS 1. What is the clinical evidence regarding the occurrence of anaphylaxis in seniors receiving IV antibiotics for common acute infections in long-term care? 2. What are the evidence-based the guidelines regarding monitoring (...) and administration of IV antibiotics to seniors with common acute infections in long-term care? KEY MESSAGE No relevant technology assessment reports, systematic reviews, meta-analyses, randomized controlled trials, non-randomized studies, or evidence-based guidelines regarding the occurrence of anaphylaxis in seniors in long term care receiving IV antibiotics or the guidelines for their use were identified. METHODS A limited literature search was conducted on key resources including PubMed, Medline

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

78. Anaphylaxis: assessment and referral after emergency treatment

#notice-of-rights). Page 2 of 26Contents Contents Introduction 5 Drug recommendations 6 Who this guideline is for 6 Patient-centred care 8 1 Recommendations 9 1.1 List of all recommendations 9 2 Notes on the scope of the guidance 12 3 Implementation 13 4 Research recommendations 14 4.1 Mediators of anaphylactic reactions 14 4.2 The frequency and effects of biphasic reactions 14 4.3 Length of observation period following emergency treatment for anaphylaxis 15 4.4 Prevalence of anaphylactic reactions (...) above may be classified as having a 'severe allergic' reaction rather than an 'anaphylactic' reaction. Throughout this guideline, anyone who presents with such signs and symptoms is classed as experiencing a 'suspected anaphylactic reaction' , and should be diagnosed as having 'suspected anaphylaxis' . People who have had a mild or moderate allergic reaction are at risk of, and may subsequently present with, suspected anaphylaxis. Certain groups may be at higher risk, either because of an existing

2011 National Institute for Health and Clinical Excellence - Clinical Guidelines

79. A Case of Anaphylaxis to Intramuscular but Not to Oral Application of Thiamine (Vitamin B1). (Abstract)

A Case of Anaphylaxis to Intramuscular but Not to Oral Application of Thiamine (Vitamin B1). We report a 78 year-old non-atopic female with polyneuropathy who started to receive monthly intramuscular injections of thiamine hydrochloride. She had an anaphylaxis after the fourth injection. Skin prick test (SPT) with pure commercially available aqueous preparations was positive for thiamine hydrochloride. A titrated, single blinded, placebo-controlled oral provocation test with thiamine

2018 Iranian journal of allergy, asthma, and immunology Controlled trial quality: uncertain

80. Randomized comparison of caregivers' ability to use epinephrine autoinjectors and prefilled syringes for anaphylaxis. Full Text available with Trip Pro

Randomized comparison of caregivers' ability to use epinephrine autoinjectors and prefilled syringes for anaphylaxis. Caregivers often incorrectly use epinephrine autoinjectors. It is unclear whether this is due to insufficient training or a difficult-to-use tool. Furthermore, the high costs of epinephrine autoinjectors may limit their availability; so low-cost prefilled syringes may be the alternative.We performed a prospective randomized trial to compare successful epinephrine administration

2018 Asian Pacific journal of allergy and immunology Controlled trial quality: uncertain

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>