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Amnioinfusion

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121. Pumps and warmers during amnioinfusion: is either necessary?

Pumps and warmers during amnioinfusion: is either necessary? Pumps and warmers during amnioinfusion: is either necessary? Pumps and warmers during amnioinfusion: is either necessary? Glantz J C, Letteney D L Authors' objectives To determine whether infusion pumps or solution warmers are associated with improved maternal or neonatal outcome during amnioinfusion. Searching MEDLINE was searched from 1983 (the earliest year in which trials of amnioinfusion in humans were reported) to 1994 (...) , and the references of published articles were examined. Study selection Study designs of evaluations included in the review Prospective studies with a control group (randomised and non-randomised trials) were included. Specific interventions included in the review The use of infusion pumps or solution warmers during amnioinfusion. Participants included in the review Pregnant women were included. Outcomes assessed in the review Maternal and neonatal outcomes: Caesarean delivery, foetal distress, presence

1996 DARE.

122. The effect of amnioinfusion on the duration of labor

The effect of amnioinfusion on the duration of labor The effect of amnioinfusion on the duration of labor The effect of amnioinfusion on the duration of labor Strong T H Authors' objectives To test the hypothesis that women receiving intrapartum amniotransfusion have more rapid labours than do controls, and to determine if amniotransfusion affects the duration of labour. Searching MEDLINE was searched for trials published in three major American obstetric and gynaecologic journals. A manual (...) the interval from membrane rupture to delivery (283 infusions, 241 control patients), whilst eight studies evaluated the length of labour (382 transfusions, 349 control patients). No study demonstrated a statistically significant shortening of the amniorrhexis to delivery interval or the overall duration of labour. The meta-analysis revealed no difference in the interval from membrane rupture to delivery (p=0.23) or the total length of labour (p=0.35). Authors' conclusions Amnioinfusion has no effect

1997 DARE.

123. Amnioinfusion for the prevention of the meconium aspiration syndrome. (Abstract)

Amnioinfusion for the prevention of the meconium aspiration syndrome. It is uncertain whether amnioinfusion (infusion of saline into the amniotic cavity) in women who have thick meconium staining of the amniotic fluid reduces the risk of perinatal death, moderate or severe meconium aspiration syndrome, or both.We performed a multicenter trial in which 1998 pregnant women in labor at 36 or more weeks of gestation who had thick meconium staining of the amniotic fluid were stratified according (...) to the presence or absence of variable decelerations in fetal heart rate and then randomly assigned to amnioinfusion or to standard care. The composite primary outcome measure was perinatal death, moderate or severe meconium aspiration syndrome, or both.Perinatal death, moderate or severe meconium aspiration syndrome, or both occurred in 44 infants (4.5 percent) of women in the amnioinfusion group and 35 infants (3.5 percent) of women in the control group (relative risk, 1.26; 95 percent confidence interval

2005 NEJM Controlled trial quality: predicted high

124. Amnioinfusion Initiative

Amnioinfusion Initiative Amnioinfusion Initiative - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Amnioinfusion Initiative The safety and scientific validity of this study is the responsibility of the study (...) by: Università degli Studi di Brescia Study Details Study Description Go to Brief Summary: The aim of this study is to compare perinatal survival in patients presenting with early spontaneous PPROM and persistent oligohydramnios, managed either conservatively or with serial amnioinfusions. Condition or disease Intervention/treatment Phase Oligohydramnios Procedure: amnioinfusion Phase 3 Detailed Description: Early spontaneous Preterm Premature Rupture of Membranes (PPROM) is associated with high perinatal

2008 Clinical Trials

125. Effect of Amnioinfusion on External Cephalic Version Successful Rate

Effect of Amnioinfusion on External Cephalic Version Successful Rate Effect of Amnioinfusion on External Cephalic Version Successful Rate - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect (...) of Amnioinfusion on External Cephalic Version Successful Rate (AMNIO) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00465712 Recruitment Status : Terminated First Posted : April 25, 2007 Last Update Posted : June 1, 2011 Sponsor: University Hospital, Tours Information provided by: University Hospital, Tours

2007 Clinical Trials

126. Transcervical intrapartum amnioinfusion for preterm premature rupture of the membranes. (Abstract)

Transcervical intrapartum amnioinfusion for preterm premature rupture of the membranes. To investigate the effect of transcervical amnioinfusion on the management of labour and neonatal outcomes in preterm premature rupture of the membranes.This clinical trial included 86 patients with premature rupture of the membranes between weeks 27 and 35 of gestation. Patients were randomly assigned to receive amnioinfusion via a two-way catheter or to the control group. Clinical management was otherwise (...) the same in both groups.Amnioinfusion decreased the frequency of variable decelerations in fetal heart rate (27.9% versus 53.5%, p<0.05) and the rate of obstetric interventions motivated by nonreassuring fetal status (13.6% versus 52.4%, p<0.05). At delivery, pH values were significantly higher in the treatment group than in the conventionally managed control group (median 7.29 versus 7.27).Intrapartum transcervical amnioinfusion for preterm premature rupture of the membranes reduced the number

2007 European journal of obstetrics, gynecology, and reproductive biology Controlled trial quality: uncertain

127. Transabdominal amnioinfusion in preterm premature rupture of membranes: a randomised controlled trial. (Abstract)

Transabdominal amnioinfusion in preterm premature rupture of membranes: a randomised controlled trial. To evaluate the role of transabdominal amnioinfusion in improving the perinatal outcomes of pregnancies complicated by preterm premature rupture of membranes (pPROM).A randomised controlled trial.A teaching hospital in Italy, obstetric unit. Population Women with singleton pregnancies complicated by pPROM, between 24 + 0 and 32 + 6 weeks of gestation.Patients were randomised 24 hours after (...) admission to our referral hospital, to expectant management with transabdominal amnioinfusion or expectant management only.The effects of transabdominal amnioinfusion on pPROM-delivery interval and on perinatal outcomes.Of the 65 women with pPROM 34 met the inclusion criteria. Seventeen women were assigned to amnioinfusion (the amnioinfusion group) and the other 17 to expectant management. Compared with the control group (median: 8 days; range: 3-14), the pPROM-delivery period was significantly longer

2005 BJOG Controlled trial quality: predicted high

128. Therapeutic amnioinfusion for intrapartum fetal distress using a pediatric feeding tube. (Abstract)

Therapeutic amnioinfusion for intrapartum fetal distress using a pediatric feeding tube. To evaluate the role of therapeutic amnioinfusion using a pediatric feeding tube in cases of intrapartum fetal distress.A randomized clinical trial including 438 women admitted in labor at Assiut University Hospital with nonreassuring fetal heart rate tracing. Using sealed opaque envelopes, the women were randomized to 2 groups. In the amnioinfusion group they underwent transcervical amnioinfusion (1000 mL (...) of warmed sterile saline solution) in addition to conventional treatment. In the control group they received conventional treatment only. The primary outcome was cesarean section rate for fetal distress. The secondary outcomes were neonatal and maternal complications.The amnioinfusion group showed a significant reduction in the rate of cesarean section for fetal distress (relative risk [RR], 0.7; 95% confidence interval [CI], 0.6-0.83), and a 30% reduction in abnormal fetal heart rate patterns (RR, 0.7

2005 International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Controlled trial quality: predicted high

129. Amnioinfusion in thick meconium. (Abstract)

Amnioinfusion in thick meconium. There are conflicting reports regarding the results of amnioinfusion in the management of meconium passage in utero. This study was done to evaluate transcervical amnioinfusion for meconium stained amniotic fluid during labour.196 women at term in early labour with meconium were randomized to receive either transcervical intrapartum amnioinfusion with saline (96) or routine obstetrical care (100). Transcervical amnioinfusion of one liter saline infused over 30 (...) was reduced from 48% to 17% (p< 0.004) using amnioinfusion with positive X-rays for meconium aspiration in only 12.5% versus 26% (p < 0.5).We concluded that transcervical intrapartum amnioinfusion is a safe, simple and inexpensive technique that reduces operative intervention and improves neonatal outcome, and is of tremendous relevance in developing countries.

2004 Indian journal of pediatrics Controlled trial quality: uncertain

130. Successful external cephalic version after amnioinfusion in a patient with preterm premature rupture of membranes. (Abstract)

Successful external cephalic version after amnioinfusion in a patient with preterm premature rupture of membranes. After hospitalization subsequent to preterm premature rupture of membranes at 29 weeks, our patient was scheduled for induction of labor at 34 weeks. When the fetus was found to be breech with oligohydramnios, amnioinfusion was performed to facilitate external cephalic version, and this successful procedure enabled the patient to deliver vaginally.

2005 American Journal of Obstetrics and Gynecology

131. Small-volume amnioinfusion: a potential stimulus of intrapartum fetal heart rate accelerations. (Abstract)

Small-volume amnioinfusion: a potential stimulus of intrapartum fetal heart rate accelerations. We describe a recurrent nonreassuring fetal heart rate pattern in which small-volume amnioinfusions apparently evoked fetal heart rate accelerations suggested fetal well-being, allowing that progressive labor that culminated in the vaginal delivery of a healthy infant.

2004 American Journal of Obstetrics and Gynecology

132. Amnioinfusion to facilitate external cephalic version after initial failure. (Abstract)

Amnioinfusion to facilitate external cephalic version after initial failure. To evaluate the effectiveness of antepartum transabdominal amnioinfusion to facilitate external cephalic version after initial failure.Women with a structurally normal fetus in breech lie at term, with a failed external cephalic version and an amniotic fluid index (AFI) less than 15 cm, were asked to participate in our study. After tocolysis with indomethacin, a transabdominal amnioinfusion was performed with an 18G (...) spinal needle. Lactated Ringers solution was infused until the AFI reached 15 cm, with a maximum of 1 L. External cephalic version was performed directly afterward.Seven women participated in the study. The gestational age of the women was between 36(+4) and 38(+3) weeks, and three women were primiparous. The AFI ranged from 4 cm to 13 cm. A median amount of 1,000 mL Ringers solution (range 700-1,000 mL) was infused per procedure. The repeat external cephalic versions after amnioinfusion were

2006 Obstetrics and Gynecology

133. Saline amnioinfusion for relief of repetitive variable decelerations: a prospective randomized study. (Abstract)

Saline amnioinfusion for relief of repetitive variable decelerations: a prospective randomized study. A prospective randomized study was undertaken in order to further investigate the effect of intrauterine saline amnioinfusion for the relief of repetitive variable decelerations in the first stage of labor. Intrauterine saline amnioinfusion corrects the oligohydramnios that makes the cord more vulnerable to compression during uterine contractions. Included in this study were 96 patients who had (...) of cesarean sections for fetal distress, being 14.8% in the infusion group as compared to 47.6% in the noninfusion group. This study clearly showed that saline amnioinfusion is a logical, simple, safe, and effective therapy for the relief of repetitive variable decelerations in the first stage of labor and can lower the incidence of cesarean sections for fetal distress in nulliparous patients. Furthermore, amnioinfusion was much superior to changes in position in treating repetitive variable decelerations.

1985 American journal of obstetrics and gynecology Controlled trial quality: uncertain

134. Prophylactic intrapartum amnioinfusion in patients with preterm premature rupture of membranes. (Abstract)

Prophylactic intrapartum amnioinfusion in patients with preterm premature rupture of membranes. Patients with preterm premature rupture of the membranes are at increased risk to develop intrapartum variable decelerations and fetal distress. Short-term saline solution amnioinfusion may be of benefit in the treatment of variable or prolonged decelerations once they appear. In an effort to assess the benefit of prophylactic amnioinfusion, patients with preterm premature rupture of the membranes (...) were studied during a 1-year period in a prospective randomized manner. Patients receiving prophylactic amnioinfusion had significantly decreased incidence and severity of variable decelerations in the first stage of labor (p less than 0.005). In the second stage of labor, the incidence of severe (p less than 0.005) and total (p less than 0.001) decelerations was also decreased in the treatment group. The umbilical arterial pH at delivery was significantly lower (p less than 0.001

1985 American journal of obstetrics and gynecology Controlled trial quality: uncertain

135. The prevention of meconium aspiration in labor using amnioinfusion. (Abstract)

The prevention of meconium aspiration in labor using amnioinfusion. In an effort to improve maternal and fetal outcome in patients laboring with thick meconium, 85 patients presenting with thick meconium were randomized to receive either amnioinfusion with 1000 mL normal saline initially and every 6 hours until delivery, or routine care. Meconium was discovered on initial examination during labor, after artificial rupture of membranes, through the use of an intrauterine pressure catheter (...) , or on amniocentesis. Labor management was otherwise routine. Forceps operations and cesarean sections were for distress or failure to progress, as indicated. Patients receiving amnioinfusion had significantly fewer low 1-minute Apgar scores, less meconium below the cords, and a significantly lower incidence of operative delivery. The only three cases of meconium aspiration syndrome occurred in infants delivered of patients receiving routine management. No adverse side effects of amnioinfusion were detected

1989 Obstetrics and Gynecology Controlled trial quality: uncertain

136. Prophylactic amnioinfusion in pregnancies complicated by oligohydramnios: a prospective study. (Abstract)

Prophylactic amnioinfusion in pregnancies complicated by oligohydramnios: a prospective study. Prophylactic amnioinfusion was assessed in term and post-dates pregnancies with decreased amniotic fluid volume. Subjects were randomly assigned to one of three groups: amnioinfusion with warmed saline solution, room-temperature saline, or control. Patients receiving prophylactic amnioinfusion had a significant decrease in both the frequency and severity of variable decelerations in the first stage (...) of labor (P = .006) and in the average total number of variable decelerations in the first and second stages of labor (P = .01) compared with controls. There was no observed effect on newborn serum electrolyte levels with amnioinfusion, nor was there any apparent benefit of infusion of warmed saline compared with room-temperature saline. In contrast to premature gestations with oligohydramnios, prophylactic amnioinfusion was not associated with a significant improvement in mean umbilical arterial

1991 Obstetrics and Gynecology Controlled trial quality: uncertain

137. A prospective, randomized evaluation of intrapartum amnioinfusion. Fetal acid-base status and cesarean delivery. (Abstract)

A prospective, randomized evaluation of intrapartum amnioinfusion. Fetal acid-base status and cesarean delivery. Pregnancies with decreased amniotic fluid volume are prediposed to umbilical cord compression and variable fetal heart rate declerations. Intrapartum amnioinfusion has been utilized in an effort to reduce cord compression. Previous studies suggested that amnioinfusion may improve the fetal metabolic state and reduce the incidence of cesarean delivery in selected patients (...) . In this study the hypothesis was tested that intrapartum amnioinfusion will relieve cord compression in pregnancies complicated by oligohydramnios and will result in a reduced incidence of fetal intolerance to labor as well as improved fetal acid-base status at delivery. Thirty-five patients fulfilling the inclusion criteria were randomized to either the control (n = 16) or amnioinfusion treatment group (n = 19). Analysis of the data suggested that the two groups were similar for the perinatal parameters

1991 Journal of Reproductive Medicine Controlled trial quality: uncertain

138. A prospective randomized study of saline solution amnioinfusion. (Abstract)

A prospective randomized study of saline solution amnioinfusion. We performed a prospective randomized study of saline solution amnioinfusion in four types of pregnancy complications: postterm pregnancy, variable decelerations in labor, preterm labor, and oligohydramnios-suspected growth retardation. A total of 100 patients were randomized, 43 to undergo amnioinfusion and 57 to be in a control group. Patients undergoing amnioinfusion had a significantly decreased incidence of postpartum (...) endometritis (2.4% vs 19%, p = 0.01) and a lower incidence of cesarean delivery that was due to fetal distress in labor (4.7% vs 16%, p = 0.07). The use of amnioinfusion also made a significant contribution to the four-quadrant ultrasonographic estimate of amniotic fluid volume (14.7 vs 9.8 cm, p less than 0.001). All other maternal and neonatal outcome parameters were similar between the two groups. We conclude that saline solution amnioinfusion in labor may be a beneficial procedure but that further

1990 American journal of obstetrics and gynecology Controlled trial quality: uncertain

139. Prophylactic amnioinfusion during labor complicated by meconium: a preliminary report. (Abstract)

Prophylactic amnioinfusion during labor complicated by meconium: a preliminary report. The purpose of this prospective and randomized study is to evaluate the safety and efficacy of prophylactic transcervical amnioinfusion in the management of labor complicated by meconium. A preexisting intrauterine pressure catheter was used for amnioinfusion. The incidence of thick meconium was significantly lower after amnioinfusion, compared with standard management (5% versus 62% p less than 0.0005 (...) ). This was also demonstrated with spectrophotometry. Significant differences between the amnioinfusion group and the control group were found for the following: arterial cord pH less than 7.20 (16% versus 38%, p less than 0.05); meconium more than trace below the vocal cords at delivery (0% versus 29%, p less than 0.05) and need for positive pressure ventilation at birth (16% versus 48%, p less than 0.05). No complications related to amnioinfusion were observed. We conclude that (1) transcervical

1989 American journal of obstetrics and gynecology Controlled trial quality: uncertain

140. Prophylactic intrapartum amnioinfusion: a randomized clinical trial. (Abstract)

Prophylactic intrapartum amnioinfusion: a randomized clinical trial. Amnioinfusion was performed in a prospective, randomized trial of 60 women in the latent phase of labor with oligohydramnios, as defined by an amniotic fluid index less than or equal to 5.0 cm. All fetuses were at least 37 weeks' gestational age, had normal baseline fetal heart rate variability, and no clinically significant fetal heart rate decelerations at the outset. Subjects in the amnioinfusion group (n = 30) were (...) titrated to and maintained at an amniotic fluid index level greater than or equal to 8.0 cm throughout labor. In the group receiving amnioinfusion, significantly lower rates of meconium passage (p = 0.04), severe variable decelerations (p = 0.04), end-stage bradycardia (p = 0.05), and operative delivery for fetal distress (p = 0.002) occurred. Significantly higher umbilical arterial blood pH values were also noted in the infusion group (p = 0.02). We conclude that prophylactic intrapartum amnioinfusion

1990 American journal of obstetrics and gynecology Controlled trial quality: uncertain

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