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Alpha Adrenergic Antagonist

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21. Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans

Adrenergic Antagonists Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Antihypertensive Agents Antioxidants Protective Agents Calcium Channel Blockers Membrane Transport Modulators Calcium-Regulating Hormones and Agents Vasodilator Agents Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists (...) Update Posted : July 3, 2018 See Sponsor: Gitte Moos Knudsen Collaborators: Center for translational Neuroscience, University of Copenhagen, Denmark Danish Center for Sleep Medicine Information provided by (Responsible Party): Gitte Moos Knudsen, Rigshospitalet, Denmark Study Details Study Description Go to Brief Summary: The project is aimed at identifying how the adrenergic antagonist 'carvedilol' modulates the effects of sleep deprivation in healthy volunteers. The study is a double-blind

2018 Clinical Trials

22. Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease

Membrane Transport Modulators Calcium-Regulating Hormones and Agents Vasodilator Agents Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists (...) Disease, Secondary Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases REM Sleep Parasomnias Parasomnias Sleep Wake Disorders Carvedilol Adrenergic Agents Adrenergic Antagonists Adrenergic beta-Antagonists Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Antihypertensive Agents Antioxidants Protective Agents Calcium Channel Blockers

2018 Clinical Trials

23. Re: Impact of Combination Therapy 5-Alpha Reductase Inhibitors (5-ARI) plus Alpha-Blockers (AB) on Erectile Dysfunction and Decrease of Libido in Patients with LUTS/BPH: A Systematic Review with Meta-Analysis. (PubMed)

-Analysis. 457-458 S0022-5347(17)74812-4 10.1016/j.juro.2017.06.030 Kaplan Steven A SA eng Journal Article Comment 2017 06 20 United States J Urol 0376374 0022-5347 0 5-alpha Reductase Inhibitors 0 Adrenergic alpha-Antagonists AIM IM Aging Male. 2016 Sep;19(3):175-181 27310433 5-alpha Reductase Inhibitors Adrenergic alpha-Antagonists Erectile Dysfunction Humans Libido Male Prostatic Hyperplasia 2017 8 19 6 0 2017 8 19 6 0 2019 3 15 6 0 ppublish 28817869 S0022-5347(17)74812-4 10.1016/j.juro.2017.06.030 (...) Re: Impact of Combination Therapy 5-Alpha Reductase Inhibitors (5-ARI) plus Alpha-Blockers (AB) on Erectile Dysfunction and Decrease of Libido in Patients with LUTS/BPH: A Systematic Review with Meta-Analysis. 28817869 2019 03 14 2019 03 14 1527-3792 198 3 2017 09 The Journal of urology J. Urol. Re: Impact of Combination Therapy 5-Alpha Reductase Inhibitors (5-ARI) plus Alpha-Blockers (AB) on Erectile Dysfunction and Decrease of Libido in Patients with LUTS/BPH: A Systematic Review with Meta

2017 The Journal of urology

24. Adrenergic System in Islet Transplantation

Propranolol Phentolamine Adrenergic Agents Adrenergic beta-Antagonists Adrenergic Antagonists Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Anti-Arrhythmia Agents Antihypertensive Agents Vasodilator Agents Adrenergic alpha-Antagonists (...) Adrenergic System in Islet Transplantation Adrenergic System in Islet Transplantation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Adrenergic System in Islet Transplantation (Aim 1 Islets) The safety

2017 Clinical Trials

25. β2-Adrenergic Receptor-Mediated HIF-1α Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia (PubMed)

was accompanied by suppressed occludin degradation and vascular endothelial growth factor (VEGF) mRNA upregulation. Interestingly, β2-adrenergic receptor (β2-AR) antagonist ICI 118551 attenuated ischemia-induced BBB damage by regulating HIF-1α expression. Double immunostaining showed that HIF-1α was upregulated in ischemic neurons but not in astrocytes andendothelial cells. Of note, HIF-1α inhibition with inhibitor YC-1 or siRNA significantly prevented OGD-induced VEGF upregulation as well as the secretion (...) β2-Adrenergic Receptor-Mediated HIF-1α Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia Disruption of the blood brain barrier (BBB) within the thrombolytic time window is an antecedent event to intracerebral hemorrhage in ischemic stroke. Our recent studies showed that 2-h cerebral ischemia induced BBB damage in non-infarcted area and secreted matrix metalloproteinase-2 (MMP-2) accounted for this disruption. However, the factors that affect MMP-2 secretion

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2017 Frontiers in molecular neuroscience

26. The efficacy of PDE5 inhibitors alone or in combination with alpha-blockers for the treatment of erectile dysfunction and lower urinary tract symptoms due to benign prostatic hyperplasia: a systematic review and meta-analysis

2014; 11(6): 1539-1545 PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Adrenergic alpha-Antagonists /therapeutic use; Drug Therapy, Combination; Erectile Dysfunction /drug therapy /etiology; Humans; Lower Urinary Tract Symptoms /drug therapy; Male; Phosphodiesterase 5 Inhibitors /therapeutic use; Prostatic Hyperplasia /complications; Randomized Controlled Trials as Topic AccessionNumber 12014019117 Date bibliographic record published 04/04/2014 Date abstract (...) The efficacy of PDE5 inhibitors alone or in combination with alpha-blockers for the treatment of erectile dysfunction and lower urinary tract symptoms due to benign prostatic hyperplasia: a systematic review and meta-analysis The efficacy of PDE5 inhibitors alone or in combination with alpha-blockers for the treatment of erectile dysfunction and lower urinary tract symptoms due to benign prostatic hyperplasia: a systematic review and meta-analysis The efficacy of PDE5 inhibitors alone

2014 DARE.

27. A meta-analysis of the vascular-related safety profile and efficacy of alpha-adrenergic blockers for symptoms related to benign prostatic hyperplasia

Adrenergic alpha-Antagonists /adverse effects; Aged; Humans; Male; Middle Aged; Prognosis; Prostatic Hyperplasia /drug therapy; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Vascular Diseases /chemically induced; Vasodilation /drug effects AccessionNumber 12009100772 Date bibliographic record published 07/04/2009 Date abstract record published 19/01/2011 Record Status This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical (...) A meta-analysis of the vascular-related safety profile and efficacy of alpha-adrenergic blockers for symptoms related to benign prostatic hyperplasia A meta-analysis of the vascular-related safety profile and efficacy of alpha-adrenergic blockers for symptoms related to benign prostatic hyperplasia A meta-analysis of the vascular-related safety profile and efficacy of alpha-adrenergic blockers for symptoms related to benign prostatic hyperplasia Nickel JC, Sander S, Moon TD CRD summary

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2008 DARE.

28. Beta Adrenergic Receptor

. Related Studies (from Trip Database) Ontology: Receptors, Adrenergic, beta-1 (C0001642) Definition (MSH) A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems. Definition (NCI) Beta 1 adrenergic receptor protein (477 (...) adrenergic fibers, Beta Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force

2018 FP Notebook

29. Beta Adrenergic Receptor Blockade as a Novel Therapy for Patients With Adenocarcinoma of the Prostate

by Histologic Type Neoplasms Genital Neoplasms, Male Urogenital Neoplasms Neoplasms by Site Genital Diseases, Male Prostatic Diseases Carvedilol Adrenergic Agents Adrenergic beta-Antagonists Adrenergic Antagonists Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Antihypertensive Agents Antioxidants Protective Agents Calcium Channel Blockers Membrane Transport Modulators Calcium-Regulating Hormones and Agents Vasodilator Agents Adrenergic alpha-1 Receptor (...) Antagonists Adrenergic alpha-Antagonists

2016 Clinical Trials

30. Treatment of Asian Flushing Syndrome With Topical Alpha Agonists

Flushing Alcohol-Related Disorders Skin Manifestations Signs and Symptoms Substance-Related Disorders Chemically-Induced Disorders Mental Disorders Brimonidine Tartrate Antihypertensive Agents Adrenergic alpha-2 Receptor Agonists Adrenergic alpha-Agonists Adrenergic Agonists Adrenergic Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs (...) Treatment of Asian Flushing Syndrome With Topical Alpha Agonists Treatment of Asian Flushing Syndrome With Topical Alpha Agonists - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment of Asian Flushing

2018 Clinical Trials

31. A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with alpha-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia

-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with alpha-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia. European Urology 2012; 61(5): 994-1003 PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Adrenergic alpha-Antagonists /therapeutic use; Carbolines /therapeutic use; Drug Therapy, Combination; Erectile Dysfunction /drug therapy; Humans; Imidazoles /therapeutic use; Lower Urinary Tract Symptoms /drug (...) unknown. Limitations of the evidence (including small samples) mean the reliability of the findings remains unclear. Authors' objectives To assess the effects of phosphodiesterase type 5 inhibitors alone or in combination with alpha 1-adrenergic blockers on lower urinary tract symptoms associated with benign prostatic hyperplasia. Searching MEDLINE/PubMed, EMBASE and The Cochrane Library were searched up to September 2011 without language restrictions; search terms were reported. Relevant reference

2012 DARE.

32. Estimating the quality-of-life impact and cost-effectiveness of alpha-blocker and anti-muscarinic combination treatment in men with lower urinary tract symptoms related to benign prostatic hyperplasia and overactive bladder

trial. JAMA 2006; 296: 2319-2328. Indexing Status Subject indexing assigned by NLM MeSH Adrenergic alpha-Antagonists /therapeutic use; Adult; Cohort Studies; Cost-Benefit Analysis; Drug Therapy, Combination /economics; Great Britain; Humans; Lower Urinary Tract Symptoms /drug therapy /etiology; Male; Middle Aged; Muscarinic Antagonists /therapeutic use; Prostatic Hyperplasia /complications; Quality of Life; State Medicine /economics; Urinary Bladder, Overactive /complications; Urination Disorders (...) Estimating the quality-of-life impact and cost-effectiveness of alpha-blocker and anti-muscarinic combination treatment in men with lower urinary tract symptoms related to benign prostatic hyperplasia and overactive bladder Estimating the quality-of-life impact and cost-effectiveness of alpha-blocker and anti-muscarinic combination treatment in men with lower urinary tract symptoms related to benign prostatic hyperplasia and overactive bladder Estimating the quality-of-life impact and cost

2012 NHS Economic Evaluation Database.

33. Alpha Adrenergic Receptor

Receptors (CNS) Inhibits Locus Ceruleus reflex arc Peripheral vasodilatation V. Medications: Alpha Adrenergics Alpha Adrenergic Agonist (Alpha Adrenergic Receptor) Alpha Non-Specific Alpha 1 Selective Methoxamine Alpha 2 Selective (See ) Alpha-methylnorepinephrine Alpha Receptor Antagonist Alpha Non-Specific Phentolamine Alpha 1 Selective (See ) Phenoxybenzamine Alpha 2 Selective Tolazoline Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search (...) Alpha Adrenergic Receptor Alpha Adrenergic Receptor Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Alpha Adrenergic Receptor Alpha

2015 FP Notebook

34. Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions

: January 11, 2019 Last Update Posted: January 29, 2019 Last Verified: January 2019 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: Yes Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Constipation Signs and Symptoms, Digestive Signs and Symptoms Alfuzosin Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists Adrenergic Antagonists Adrenergic Agents Neurotransmitter Agents Molecular Mechanisms (...) Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2013 Clinical Trials

35. Alpha blockers in the management of ureteric lithiasis: A meta-analysis. (PubMed)

, was conducted using PubMed and Embase. All randomised trials comparing α-blocker monotherapy to placebo or standard therapy were included. Stone expulsion rate was the primary outcome measure. Secondary outcome measures were time to stone expulsion, analgesic usage and pain scores. Subgroup analyses assessed individual adrenergic antagonists and variations in standard therapy. Sensitivity analysis was based on stone location, stone size, Cochrane Risk of Bias score and study protocol. Summary effects were (...) Alpha blockers in the management of ureteric lithiasis: A meta-analysis. Effective medical expulsion for ureteric stones with α-blockers offers numerous advantages over surgical alternatives. However, its effectiveness remains uncertain and with the publication of new trial data, the available evidence requires reappraisal.The aim of this study was to assess the efficacy of α-blockers the management of ureteric lithiasis.A systematic review of the literature, with predefined search criteria

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2017 International journal of clinical practice

36. [Alpha-blockers as medical expulsive therapy for ureteral stones].

, Deutschland. ger Journal Article Meta-Analysis Review Alpha-Blocker zur medikamentösen Expulsionstherapie für Harnleitersteine. Germany Urologe A 1304110 0340-2592 0 Adrenergic alpha-1 Receptor Antagonists IM Adolescent Adrenergic alpha-1 Receptor Antagonists administration & dosage Adult Aged Aged, 80 and over Comorbidity Hospitalization statistics & numerical data Humans Middle Aged Pain epidemiology prevention & control Prevalence Risk Factors Treatment Outcome Ureteral Calculi drug therapy (...) [Alpha-blockers as medical expulsive therapy for ureteral stones]. 27246474 2017 05 09 2018 11 13 1433-0563 55 6 2016 Jun Der Urologe. Ausg. A Urologe A [Alpha-blockers as medical expulsive therapy for ureteral stones]. 813-6 10.1007/s00120-016-0140-3 Schmidt S S UroEvidence@Deutsche Gesellschaft für Urologie, Kuno-Fischer-Str. 8, 14057, Berlin, Deutschland. schmidt@dgu.de. Miernik A A Department Chirurgie Klinik für Urologie, Universitätsklinikum Freiburg, Hugstetter Str. 55, 79106, Freiburg

2017 Der Urologe. Ausg. A

37. Pelvic floor muscle therapy or alpha-blocking agents for treatment of men with lower urinary tract symptoms: An exploratory randomized controlled trial. (PubMed)

of Groningen, Groningen, the Netherlands. Blanker Marco H MH Department of General Practice, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Dekker Janny H JH Department of General Practice, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. eng Journal Article 2017 03 22 Australia Int J Urol 9440237 0919-8172 Int J Urol. 2017 Jun;24(6):475 28503766 adrenergic alpha-1 receptor antagonists behavior therapy lower urinary tract (...) Pelvic floor muscle therapy or alpha-blocking agents for treatment of men with lower urinary tract symptoms: An exploratory randomized controlled trial. 28332234 2018 12 31 1442-2042 24 6 2017 06 International journal of urology : official journal of the Japanese Urological Association Int. J. Urol. Pelvic floor muscle therapy or alpha-blocking agents for treatment of men with lower urinary tract symptoms: An exploratory randomized controlled trial. 473-474 10.1111/iju.13339 Hut Jan J

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2017 International journal of urology : official journal of the Japanese Urological Association

38. Prophylactic Alpha-blockers in the Prevention of Urinary Retention Post Inguinal Hernia Repair

in and Exported from the U.S.: No Additional relevant MeSH terms: Layout table for MeSH terms Hernia Hernia, Inguinal Urinary Retention Pathological Conditions, Anatomical Hernia, Abdominal Urination Disorders Urologic Diseases Tamsulosin Adrenergic alpha-Antagonists Adrenergic alpha-1 Receptor Antagonists Adrenergic Antagonists Adrenergic Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Urological Agents (...) have been demonstrated to be rich in alpha-1 adrenergic receptors. Our research idea is novel because there has been no prior prospective study conducted using alpha-blockers to reduce post-operative urinary retention in patients undergoing inguinal hernia repair. The proposed research is important as existing studies that sought to understand POUR have merely established the risks factors involved. Despite so, the incidence of POUR remains high and no studies to date have investigated the use

2017 Clinical Trials

39. Preoperative Alpha Blockade for Pheochromocytoma

-regulated Drug Product: Yes Studies a U.S. FDA-regulated Device Product: No Product Manufactured in and Exported from the U.S.: No Additional relevant MeSH terms: Layout table for MeSH terms Pheochromocytoma Paraganglioma Carotid Body Tumor Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms, Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms, Nerve Tissue Paraganglioma, Extra-Adrenal Doxazosin Phenoxybenzamine Antihypertensive Agents Adrenergic alpha-1 Receptor Antagonists (...) Adrenergic alpha-Antagonists Adrenergic Antagonists Adrenergic Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Vasodilator Agents

2017 Clinical Trials

40. Resource utilization and costs associated with the addition of an antimuscarinic in patients treated with an alpha-blocker for the treatment of urinary symptoms linked to benign prostatic hyperplasia (PubMed)

100968571 1471-2490 0 Adrenergic alpha-Antagonists 0 Muscarinic Antagonists IM Adrenergic alpha-Antagonists administration & dosage economics Aged Drug Therapy, Combination Health Care Costs trends Health Resources economics statistics & numerical data Humans Lower Urinary Tract Symptoms drug therapy economics epidemiology Male Middle Aged Muscarinic Antagonists administration & dosage economics Prostatic Hyperplasia drug therapy economics epidemiology Retrospective Studies Spain epidemiology (...) Resource utilization and costs associated with the addition of an antimuscarinic in patients treated with an alpha-blocker for the treatment of urinary symptoms linked to benign prostatic hyperplasia 28899370 2018 10 05 2018 12 02 1471-2490 17 1 2017 Sep 12 BMC urology BMC Urol Resource utilization and costs associated with the addition of an antimuscarinic in patients treated with an alpha-blocker for the treatment of urinary symptoms linked to benign prostatic hyperplasia. 83 10.1186/s12894

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2017 BMC urology

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