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Alcohol Tremor

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41. Ketogenic Diet (KD) in Alcoholism

Institutes of Health Clinical Center (CC) ( National Institute on Alcohol Abuse and Alcoholism (NIAAA) ) Study Details Study Description Go to Brief Summary: Background: A ketogenic diet (KD) is high in fat and low in carbohydrates. Research has shown that a KD can lessen tremor in animals withdrawing from alcohol. KD can also help people who have difficulties with thinking, sleep, and mood. Researchers want to see if KD can lessen symptoms of alcohol withdrawal in people with alcohol use disorder (...) Ketogenic Diet (KD) in Alcoholism Ketogenic Diet (KD) in Alcoholism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Ketogenic Diet (KD) in Alcoholism The safety and scientific validity of this study

2017 Clinical Trials

42. Finger tremor in alcoholic patients. (PubMed)

Finger tremor in alcoholic patients. 5866607 1966 06 23 2018 11 13 0022-3050 28 6 1965 Dec Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Finger tremor in alcoholic patients. 529-32 Carrie J R JR eng Journal Article England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM Adult Alcoholism complications Female Fingers Humans Male Middle Aged Psychoses, Alcoholic Tremor 1965 12 1 1965 12 1 0 1 1965 12 1 0 0 ppublish 5866607 PMC495956 J Physiol. 1954 Feb

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1965 Journal of neurology, neurosurgery, and psychiatry

43. The Essential Tremor (ET) and Parkinson Disease (PD) Tremor Acute Stimulation Study

The Essential Tremor (ET) and Parkinson Disease (PD) Tremor Acute Stimulation Study The Essential Tremor (ET) and Parkinson Disease (PD) Tremor Acute Stimulation Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. The Essential Tremor (ET) and Parkinson Disease (PD) Tremor Acute Stimulation Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01940406 Recruitment Status : Withdrawn (Internal desicions) First Posted : September 12, 2013 Last Update Posted : February 23, 2018 Sponsor: Rainbow

2013 Clinical Trials

44. Can Biological markers predict Alcohol Withdrawal

presenting to the ED] are [CDT, Gamma GT and MCV reliable biological markers] at [predicting patients likely to suffer alcohol withdrawal syndrome?] Clinical Scenario A 47 year old female patient is brought to your ED. She admits to regular alcohol consumption, is tachycardic with extremities tremor and ataxia. She asks you for something to help her with her symptoms. She has not drunk any alcohol for two days. You wonder if any biological marker would allow you to predict if she is really at risk (...) Can Biological markers predict Alcohol Withdrawal BestBets: Can Biological markers predict Alcohol Withdrawal Can Biological markers predict Alcohol Withdrawal Report By: Neal Larkman - Medical Student Search checked by Dr John-Paul Williamson - Registrar Emergency Medicine Institution: Manchester Royal Infirmary Date Submitted: 28th June 2007 Date Completed: 24th July 2013 Last Modified: 24th July 2013 Status: Green (complete) Three Part Question In [Adult patients with chronic alcohol abuse

2013 BestBETS

45. Cala ONE Device for Essential Tremor

medical device, such as a pacemaker, defibrillator, or deep brain stimulator Previous thalamotomy procedure, including Stereotactic Thalamotomy, Gamma Knife Radiosurgical Thalamotomy, and focused ultrasound, for the treatment of tremor Suspected or diagnosed epilepsy or other seizure disorder Pregnant Swollen, infected, inflamed areas, or skin eruptions, open wounds, or cancerous lesions of skin at stimulation site Peripheral neuropathy affecting the tested upper extremity Alcoholism (score of 4 (...) to study enrollment Botulinum Toxin injection for hand tremor within 6 months prior to study enrollment Current participation in any other interventional research study Previous participation in any other Cala Health interventional research study Alcohol or caffeine consumption within 12 hours of study enrollment Subjects already taking medications for their essential tremor will remain on their medications during the study with no changes in medication type or dosage levels. Contacts and Locations Go

2015 Clinical Trials

46. An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor

An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. An Efficacy/Safety (...) Study of Perampanel for Reducing Essential Tremor The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02668146 Recruitment Status : Unknown Verified September 2016 by Adrian Handforth, MD, VA Greater Los Angeles Healthcare System. Recruitment status was: Active, not recruiting First Posted : January 29

2015 Clinical Trials

47. MKSAP: 54-year-old man with a tremor

difficulty writing and using utensils during meals. He has no associated slowness, stiffness, or change in gait. The patient started a trial of propranolol, which provided better control of the tremor, but after a few months, the tremor again worsened. He has subsequently been taking clonazepam without significant relief of symptoms. Alcohol, which the patient uses infrequently, temporarily diminishes the tremor. He also has kidney stones and glaucoma. His father and two sisters have a similar tremor (...) MKSAP: 54-year-old man with a tremor Propranolol and primidone are first-line therapies for essential tremor MKSAP: 54-year-old man with a tremor | | December 19, 2015 4 Shares Test your medicine knowledge with the , in partnership with the . A 54-year-old man is seen for follow-up evaluation of a tremor in his upper extremities that has been present since age 20 years. The tremor was mild for many years and did not interfere with his work but has become more prominent in recent years. He has

2015 KevinMD blog

48. Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor

Volunteers: Yes Criteria Inclusion Criteria: Essential Tremor diagnosed by criteria listed in the Consensus statement of the Movement Disorders Society on Tremor Age 18 - 85 years of age Motor skills allowing for capability to complete evaluations Medically cleared for undergoing anesthesia and DBS surgery Exclusion Criteria: Dementia per DSM-V criteria Medical or other condition precluding MRI History of supraspinal CNS disease other than Essential Tremor Alcohol use of more than 4 drinks per day (...) Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2015 Clinical Trials

49. Deep braIn Stimulation for Tremor TractographIC Versus Traditional

Deep braIn Stimulation for Tremor TractographIC Versus Traditional Deep braIn Stimulation for Tremor TractographIC Versus Traditional - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Deep braIn Stimulation (...) for Tremor TractographIC Versus Traditional (DISTINCT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02491554 Recruitment Status : Recruiting First Posted : July 8, 2015 Last Update Posted : November 13, 2017 See Sponsor

2015 Clinical Trials

50. Cognitive demands during quiet standing elicit truncal tremor in two frequency bands: differential relations to tissue integrity of corticospinal tracts and cortical targets (PubMed)

. As cerebellar system disruption is a common concomitant of alcoholism, we examined 46 alcoholics and 43 controls with a force platform to derive physiological indices of quiet standing during cognitive (solving simple, mental arithmetic problems) and visual (eyes closed) challenges. Also tested were relations between tremor velocity and regional gray matter and white matter tissue quality measured with the diffusion tensor imaging (DTI) metric of mean diffusivity (MD), indexing disorganized microstructure (...) . Spectral analysis of sway revealed greater tremor in alcoholic men than alcoholic women or controls. Cognitive dual-tasking elicited excessive tremor in two frequency bands, each related to DTI signs of degradation in separate brain systems: tremor velocity at a low frequency (2-5 Hz/0-2 Hz) correlated with higher MD in the cerebellar hemispheres and superior cingulate bundles, whereas tremor velocity at a higher frequency (5-7 Hz) correlated with higher MD in the motor cortex and internal capsule

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2015 Frontiers in human neuroscience

51. Lead Exposure and Tremor among Older Men: The VA Normative Aging Study (PubMed)

lead and bone lead-a biomarker of cumulative lead exposure.We measured tibia (n = 670) and patella (n = 672) bone lead and blood lead (n = 807) among older men (age range, 50-98 years) in the VA Normative Aging Study cohort. A tremor score was created based on an approach using hand-drawing samples. ALAD genotype was dichotomized as ALAD-2 carriers or not. We used linear regression adjusted for age, education, smoking, and alcohol intake to estimate the associations between lead biomarkers (...) Lead Exposure and Tremor among Older Men: The VA Normative Aging Study Tremor is one of the most common neurological signs, yet its etiology is poorly understood. Case-control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in the δ-aminolevulinic acid dehydrogenase (ALAD) gene.We aimed to examine the relationship between lead and tremor, including modification by ALAD, in a prospective cohort study, using both blood

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2015 Environmental health perspectives

52. Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor (PubMed)

are not required. Enhanced synaptic norepinephrine or blockade of ionic glutamate receptors suppresses tremor, whereas enhanced synaptic serotonin exacerbates tremor. Benzodiazepines and muscimol suppress tremor. Alcohol suppresses harmaline tremor but exacerbates harmaline-associated neural damage. Recent investigations on the mechanism of harmaline tremor have focused on the T-type calcium channel.Like essential tremor, harmaline tremor involves the cerebellum, and classic medications for essential tremor (...) Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature. This drug-induced action tremor has been proposed as a model of essential tremor. Here we review what is known about harmaline tremor.Using the terms harmaline and harmine on PubMed, we searched for papers describing the effects

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2012 Tremor and Other Hyperkinetic Movements

53. Octanoic Acid Suppresses Harmaline-Induced Tremor in Mouse Model of Essential Tremor (PubMed)

Octanoic Acid Suppresses Harmaline-Induced Tremor in Mouse Model of Essential Tremor Recent work exploring the use of high-molecular weight alcohols to treat essential tremor (ET) has identified octanoic acid as a potential novel tremor-suppressing agent. We used an established harmaline-based mouse model of ET to compare tremor suppression by 1-octanol and octanoic acid. The dose-related effect on digitized motion power within the tremor bandwidth as a fraction of overall motion power (...) was analyzed. Both 1-octanol and octanoic acid provided significant reductions in harmaline tremor. An 8-carbon alkyl alcohol and carboxylic acid each suppress tremor in a pre-clinical mouse model of ET. Further studies are warranted to determine the safety and efficacy of such agents in humans with ET.

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2012 Neurotherapeutics

54. Deep Brain Stimulation (DBS) for the Suppression of Tremor

Deep Brain Stimulation (DBS) for the Suppression of Tremor Deep Brain Stimulation (DBS) for the Suppression of Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Deep Brain Stimulation (DBS (...) ) for the Suppression of Tremor The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02087046 Recruitment Status : Unknown Verified February 2015 by Abbott Medical Devices. Recruitment status was: Active, not recruiting First Posted : March 14, 2014 Last Update Posted : March 2, 2015 Sponsor: Abbott Medical Devices

2014 Clinical Trials

55. Botulinum Toxin A to Treat Arm Tremor

should be reached 4 weeks before screening and intended for the time during the study drug evaluation. Trauma to the central nervous system or the nerves of the target limb within the three months preceding the onset of tremor. Evidence of psychogenic origins of tremor. Life habits (e.g. smoking, alcohol or substance abuse) prejudicial to study participation. Prior surgery to treat tremor Recent (16 weeks) treatment with any Botulinum toxin product for any reason. Relevant recent or planned surgery (...) Botulinum Toxin A to Treat Arm Tremor Botulinum Toxin A to Treat Arm Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Botulinum Toxin A to Treat Arm Tremor The safety and scientific validity

2014 Clinical Trials

56. Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation

Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation (ELECTRE2) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02052271 Recruitment Status : Unknown Verified April 2016 by Institut National de la Santé Et

2014 Clinical Trials

57. The Hangover: Pathophysiology and Treatment of an Alcohol-Induced Hangover

The Hangover: Pathophysiology and Treatment of an Alcohol-Induced Hangover The Hangover: Pathophysiology and Treatment of an Alcohol-Induced Hangover – Clinical Correlations Search The Hangover: Pathophysiology and Treatment of an Alcohol-Induced Hangover May 27, 2011 5 min read By Anthony Tolisano Faculty Peer Reviewed The sunlight forces its way into your eyes, stabbing at your cortex. Suddenly, a wave of nausea and diarrhea grips your stomach, threatening to evacuate its contents. You rush (...) to the bathroom, tripping over the clothes that speckle your apartment. Your heart pounds inside your chest and your hands shake ever so subtly. Your mind is in a fog and the details of last night’s party are a blur. Sound familiar? If you’re anything like the millions of people who have ever drunk too much alcohol, you’ll immediately recognize the sordid signs of a hangover. It’s a condition that is well recognized yet poorly understood. Descriptions abound in pop culture and literature, saturating

2011 Clinical Correlations

58. Drug and Alcohol Abuse amongst Anaesthetists - Guidance on Identification and Management 2

or hypersomnia • Dysphoric mood • Craving for drugs • Lethargy and fatigue, depression, suicidal thoughts Signs and symptoms of alcohol withdrawal • Tremor: tongue, eyelids, outstretched hands • Agitation, insomnia • Transient visual, auditory, tactile hallucinations or illusions • Nausea, retching, vomiting, sweating • Delirium tremens – confusion, disorientation, hallucinations, agitation, pyrexia • Grand mal convulsions Support Addicted doctors feel isolated and need intense and long term support (...) Drug and Alcohol Abuse amongst Anaesthetists - Guidance on Identification and Management 2 2 Drug and Alcohol Abuse amongst Anaesthetists Guidance on Identification and Management Published by The Association of Anaesthetists of Great Britain and Ireland 21 Portland Place, London, W1B 1PY Telephone 020 7631 1650 Fax 020 7631 4352 info@aagbi.org www.aagbi.org March 2011 1 Membership of the working party (Details correct at the start of the working party process) Dr Diana Dickson Chair and AAGBI

2011 Association of Anaesthetists of GB and Ireland

59. Alcohol Withdrawal

) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Alcohol Withdrawal Delirium (C0001957) Definition (MSH) An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include CONFUSION; DELUSIONS; vivid HALLUCINATIONS; TREMOR; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may (...) occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175) Definition (PSY) Acute alcoholic, psychotic condition characterized by intense tremors, anxiety, hallucinations, and delusions. Concepts Disease or Syndrome ( T047 ) MSH ICD9 291.0 ICD10 SnomedCT 192211007 , 154853008 , 8635005 DSM4 291.0 English Delirium Tremens , Delirium, Alcohol Withdrawal , Men & behav dis due alcohl: withdrawl state with delirium , Mental and behavioral

2018 FP Notebook

60. Essential Tremor (Overview)

of maintenance medical therapy for essential tremor. These medications provide good benefit, reducing tremor amplitude in approximately 50-70% of patients. [ , , ] Some patients require only intermittent tremor reduction (eg, to attend a meeting or engage in a social activity). For these patients, a cocktail or beer prior to the activity may be sufficient, or they may take propranolol (10-40 mg) approximately one half hour prior to the event. Alcohol consumption is not an appropriate maintenance therapy (...) . Mov Disord . 2007 Aug 15. 22(11):1573-80. . Benito-Leon J, Louis ED, Bermejo-Pareja F. Elderly-onset essential tremor is associated with dementia. Neurology . 2006 May 23. 66(10):1500-5. . Klebe S, Stolze H, Grensing K, Volkmann J, Wenzelburger R, Deuschl G. Influence of alcohol on gait in patients with essential tremor. Neurology . 2005 Jul 12. 65(1):96-101. . Daniels C, Peller M, Wolff S, et al. Voxel-based morphometry shows no decreases in cerebellar gray matter volume in essential tremor

2014 eMedicine.com

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