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Alcohol Tremor

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21. A Phase 2 Study of CX-8998 in Adults With Tremor Associated With Parkinson's Disease

or gamma knife thalamotomy) for treatment of tremor or Parkinson's disease. Use of medication(s) in the past month that might produce tremor or interfere with the evaluation of tremor. Inability to refrain from use of medication/substance(s) that might produce tremor or interfere with the evaluation of tremor on study visit days. Positive urine drug screen for drugs of abuse, except if this is explained by use of an allowed prescription medicine. Regular use of more than two units of alcohol per day (...) A Phase 2 Study of CX-8998 in Adults With Tremor Associated With Parkinson's Disease A Phase 2 Study of CX-8998 in Adults With Tremor Associated With Parkinson's Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

22. A Clinical Study to Evaluate CAD-1883 in Essential Tremor

A Clinical Study to Evaluate CAD-1883 in Essential Tremor A Clinical Study to Evaluate CAD-1883 in Essential Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Clinical Study to Evaluate CAD-1883 (...) in Essential Tremor The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03688685 Recruitment Status : Recruiting First Posted : September 28, 2018 Last Update Posted : February 15, 2019 See Sponsor: Cadent Therapeutics Information

2018 Clinical Trials

23. Familial Cortical Myoclonic Tremor and Epilepsy, an Enigmatic Disorder: From Phenotypes to Pathophysiology and Genetics. A Systematic Review Full Text available with Trip Pro

Familial Cortical Myoclonic Tremor and Epilepsy, an Enigmatic Disorder: From Phenotypes to Pathophysiology and Genetics. A Systematic Review Familial Cortical Myoclonic Tremor and Epilepsy, an Enigmatic Disorder: From Phenotypes to Pathophysiology and Genetics. A Systematic Review \ Log in Log in Don't have an account? -------------- OR -------------- Email/Username: Password: You can Log in Reading: Familial Cortical Myoclonic Tremor and Epilepsy, an Enigmatic Disorder: From Phenotypes to P (...) ... Share: Download Reviews Familial Cortical Myoclonic Tremor and Epilepsy, an Enigmatic Disorder: From Phenotypes to Pathophysiology and Genetics. A Systematic Review Authors: Tom van den Ende , Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Academic Medical Center, Amsterdam, NL Sarvi Sharifi , Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Academic Medical Center, Amsterdam, NL Sandra M. A. van der Salm , Brain Center Rudolf Magnus

2018 Tremor and Other Hyperkinetic Movements

24. Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor

Society on Tremor, 1998. We will recruit patients displaying hand tremors in each group as the follows: Hand tremor patients in ET group. Dystonic hand tremor patients in pDT group. Cervical dystonia (CD) patients or spasmodic dysphonia and hand tremor without clinical evidence of hand dystonia in TAWD group. Ability to give informed consent. Ability to comply with all study procedures, based on the judgment by the investigator(s). Agree to not drink caffeine or alcohol for 48 hours before (...) used illegal drugs within the past 6 months based on history. The intent is to exclude those with drug use that may affect study results. Participants who appear to be intoxicated at the time of testing will be rescheduled. Has more than 7 alcoholic drinks a week in the case of a woman and 14 alcoholic drinks a week in the case of a man. Abnormal findings on neurologic exam (other than tremor and dystonia in patient group) Has had a brain tumor, a stroke, head trauma, epilepsy or a history

2017 Clinical Trials

25. Adverse Drug Reactions to Disulfiram Treatment with or without Alcohol Challenge in the Indian Setting: Systematic Review Full Text available with Trip Pro

concomitantly use alcohol and disulfiram due to the accumulation of acetaldehyde. DER may develop within 5–15 minutes of alcohol intake and include flushing, sweating, nausea, vomiting, palpitations, dyspnoea, tremors, confusion, restlessness, drowsiness, and hypotension. 3 The general side effects of disulfiram in the absence of alcohol con- sumption are a headache, general weakness, and diz- ziness which may subside within weeks of the onset of therapy. 4 Disulfiramhas been used for treating alcohol (...) Adverse Drug Reactions to Disulfiram Treatment with or without Alcohol Challenge in the Indian Setting: Systematic Review Journal of Postgraduate Medicine, Education and Research, January-March 2019;53(1):21-30 21 JPMER ASSIST linked Screening in Workplace Adverse Drug Reactions to Disulfiram Treatment with or without Alcohol Challenge in the Indian Setting: Systematic Review 1 Jaison Joseph, 2 Debasish Basu JPMER 10.5005/jp-journals-10028-1307 ABSTRACT Background: Disulfiram has been used

2019 Journal of Postgraduate Medicine, Education and Research

26. Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor

Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results (...) information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing

2016 Clinical Trials

27. Alcohol: Adult Unhealthy Drinking

. • For most patients, alcohol withdrawal may be managed within Primary Care in an outpatient setting, provided the patient has a reliable support network. • Pharmacologic treatment of alcohol withdrawal may be considered for patients with moderate or severe withdrawal symptoms, including increased systolic blood pressure, fever, tachycardia, agitation, insomnia, and tremors. 3 Background In the United States, the estimated prevalence of unhealthy drinking—which includes risky drinking and alcohol use (...) of alcohol withdrawal include anxiety, restlessness, tremor, insomnia, headache, palpitations, gastrointestinal disturbances, sweating, increased systolic blood pressure, rapid breathing, tachycardia, mild fever, problems with memory, and confusion. Withdrawal seizures, when they occur, begin within 48 hours of cessation of alcohol use. Delirium tremens—the most severe form of withdrawal—has a later onset, at 3–5 days after cessation of drinking. If untreated, delirium is associated with high mortality

2016 Kaiser Permanente Clinical Guidelines

28. Alcohol - problem drinking: How should I screen for problem drinking?

, anxiety, emotional lability, insomnia, irritability, diaphoresis, headache, and fine tremor. Moderate — worsening mild symptoms plus agitation and coarse tremor. Severe/delirium tremens — worsening moderate symptoms plus confusion/delirium, generalised tonic-clonic seizures (this may be the first manifestation of alcohol withdrawal for some people), auditory, visual, or tactile hallucinations, hyperthermia subsequent to psychomotor agitation. Note: Mild to moderate withdrawal may start as early as 4 (...) Alcohol - problem drinking: How should I screen for problem drinking? How to screen | Diagnosis | Alcohol - problem drinking | CKS | NICE Search CKS… Menu How to screen Alcohol - problem drinking: How should I screen for problem drinking? Last revised in February 2018 How should I screen for problem drinking? Tailor discussions on alcohol and screening according to the person's needs: Take into account that stigma and discrimination are often associated with alcohol misuse and that minimising

2017 NICE Clinical Knowledge Summaries

29. Finding Quality Addiction Care in Canada: Drug and Alcohol Treatment Guide

and some prescription medications can be dangerous and even life threatening. A doctor should always supervise withdrawal. Withdrawal management (detox) Better known as detoxification or detox, withdrawal management helps people who are physically dependent on alcohol or other drugs safely withdraw from them. Withdrawal symptoms range from mild (e.g., anxiety, tremors, poor sleep) to severe and potentially life- threatening, and can include: • Hallucinations; • Racing heart; • High blood pressure (...) Finding Quality Addiction Care in Canada: Drug and Alcohol Treatment Guide Finding Quality Addiction Care in Canada Drug and Alcohol Treatment Guide November 2017This publication has been reproduced and adapted from the Guide to Finding Quality Addiction Treatment, with permission from The National Center on Addiction and Substance Abuse located in New York, NY , USA. However, The National Center on Addiction and Substance Abuse has neither reviewed nor endorsed this guide, and the Canadian

2017 Canadian Centre on Substance Abuse

31. Alcohol toolkit

Alcohol toolkit A toolkit for improving care June 2015 Alcohol The Royal College of Emergency Medicine: Alcohol Toolkit © The Royal College of Emergency Medicine (2015) 2 Foreword from the President of the Royal College of Emergency Medicine It is a great privilege to introduce this toolkit – the first we have issued as a Royal College - and the subject could not be more worthy. The EM profession has major concerns with current licensing laws, the increased number of retail outlets selling (...) alcohol, the unwelcome association of alcohol sponsorship with major sporting events and the failure, to date, to introduce a minimum unit price for alcohol. Although we have published numerous articles highlighting these concerns, they have mostly appeared in the ‘dull but worthy’ section of national newspapers and hence transited to recycling bins without troubling the intended audience. It is heartening to know that the same fate will not befall this toolkit! Not only is this toolkit comprehensive

2015 Royal College of Emergency Medicine

32. Alcohol challenge and sensitivity to change of the essential tremor rating assessment scale. Full Text available with Trip Pro

Alcohol challenge and sensitivity to change of the essential tremor rating assessment scale. The ability of the Essential Tremor (ET) Rating Assessment Scale (TETRAS) to detect changes in tremor severity is unknown.Fifteen adult ET patients received a single oral ethanol dose calculated to reach 0.05 g/dL breath alcohol content (brAC). Effects were investigated independently with accelerometry and TETRAS.Accelerometry data were log-transformed and a cumulative score logACC(R+L) was calculated

2013 Movement Disorders

33. Octanoic acid in alcohol-responsive essential tremor: A randomized controlled study. Full Text available with Trip Pro

Octanoic acid in alcohol-responsive essential tremor: A randomized controlled study. To assess safety and efficacy of an oral, single, low dose of octanoic acid (OA) in subjects with alcohol-responsive essential tremor (ET).We conducted a double-blind, placebo-controlled, crossover, phase I/II clinical trial evaluating the effect of 4 mg/kg OA in 19 subjects with ET. The primary outcome was accelerometric postural tremor power of the dominant hand 80 minutes after administration. Secondary (...) outcomes included digital spiral analysis, pharmacokinetic sampling, as well as safety measures.OA was safe and well tolerated. Nonserious adverse events were mild (Common Terminology Criteria for Adverse Events grade 1) and equally present after OA and placebo. At the primary outcome, OA effects were not different from placebo. Secondary outcome analyses of digital spiral analysis, comparison across the entire time course in weighted and nonweighted accelerometry, as well as nondominant hand tremor

2013 Neurology Controlled trial quality: predicted high

34. Tremor

and older people, but anyone can have them. The cause of tremors is a problem in the parts of the brain that control muscles in the body or in specific parts of the body, such as the hands. They commonly occur in otherwise healthy people. They may also be caused by problems such as Multiple sclerosis Stroke Traumatic brain injury Alcohol abuse and withdrawal Certain medicines Some forms are inherited and run in families. Others have no known cause. There is no cure for most tremors. Treatment to relieve (...) Tremor Tremor Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Tremor Tremor Aka: Tremor From Related Chapters II. Definition Body part

2018 FP Notebook

35. Finger tremor in alcoholic patients. Full Text available with Trip Pro

Finger tremor in alcoholic patients. 5866607 1966 06 23 2018 11 13 0022-3050 28 6 1965 Dec Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Finger tremor in alcoholic patients. 529-32 Carrie J R JR eng Journal Article England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM Adult Alcoholism complications Female Fingers Humans Male Middle Aged Psychoses, Alcoholic Tremor 1965 12 1 1965 12 1 0 1 1965 12 1 0 0 ppublish 5866607 PMC495956 J Physiol. 1954 Feb

1965 Journal of neurology, neurosurgery, and psychiatry

36. A Pilot Study of the Cala ONE Device for Essential Tremor

or above in any one of the hand items) Currently or previously prescribed either propranolol or primidone for the treatment of essential tremor Stable dose of tremor medications for 30 days prior to study entry Stable dose of antidepressant medications for 90 days prior to study entry Willing to comply with study protocol requirements including: remaining on a stable dosage of tremor and antidepressant medications, if applicable, during the duration of the study; no significant alcohol or caffeine (...) A Pilot Study of the Cala ONE Device for Essential Tremor A Pilot Study of the Cala ONE Device for Essential Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Pilot Study of the Cala ONE Device

2017 Clinical Trials

37. A Phase 2 RCT Study of CX-8998 for Essential Tremor

cause or explain subject's tremor, including, but not limited to: a. Parkinson's disease b. dystonia c. cerebellar disease, other than essential tremor d. Traumatic Brain Injury e. alcohol abuse or withdrawal f. mercury poisoning g. hyperthyroidism h. pheochromocytoma i. head trauma or cerebrovascular disease within 3 months prior to the onset of essential tremor j. multiple sclerosis k. polyneuropathy l. family history of Fragile X syndrome Prior MR-guided Focused Ultrasound or surgical (...) Inability to refrain from use of medication/substance(s) that might produce tremor or interfere with the evaluation of tremor on study visit days, such as but not limited to stimulant decongestants, beta-agonist bronchodilators, caffeine, alcohol and tobacco, based on Investigator assessment at baseline. Positive urine drug screen. Regular use of more than two units of alcohol per day. Sporadic use of a benzodiazepine, sleep medication or anxiolytic to improve sleep performance. Stable use

2017 Clinical Trials

38. Clinical and Physiological Studies of Tremor Syndromes

to not drink caffeine or alcohol for 12 hours before phenotyping and selected thematic study visits because both agents can modify brain activity and may confound outcome measures. INCLUSION CRITERIA FOR HEALTHY VOLUNTEERS: Age 18 or older. Able to give informed consent. Agree to not consume caffeine or alcohol for 12 hours before selected thematic study visits because both agents may modify the activity of the brain during the study. EXCLUSION CRITERIA FOR TREMOR PATIENTS: Problematic alcohol use (...) , as defined by a score of 8 or higher on the WHO Alcohol Use Disorders Identification Test (AUDIT). History of a brain tumor, a stroke, traumatic brain injury, epilepsy or a history of seizures. History of psychotic disorder, Bipolar Disorder or a current depressive episode. History or clinical evidence of another neurologic disorder than a tremor syndrome as defined above, which may interfere with the ability to comply with protocol requirements or interpret the obtained results. EXCLUSION CRITERIA

2017 Clinical Trials

39. Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor

or present history of the following conditions will be excluded from the study; Except for SD and dystonic VT, any neurological disorders, such as stroke, movement disorders, brain tumors, traumatic brain injury with loss of consciousness, ataxias, myopathies, myasthenia gravis, demyelinating diseases, alcoholism, drug dependence. Patients with tremor affecting other body parts will be excluded from the study. All patients who have dystonic movements in the body regions other than the larynx (...) Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Sodium Oxybate in Spasmodic Dysphonia and Voice

2017 Clinical Trials

40. Public Knowledge and Attitude toward Essential Tremor: A Questionnaire Survey Full Text available with Trip Pro

/3 were either unsure or thought ET was the same disease as PD, 1/4 thought that ET was the same condition as frailty- or aging-associated tremor, 2/3 attributed it to odd causes (e.g., trauma or alcohol abuse), only 1/3 knew of the existence of therapeutic brain surgery, fewer than 1/2 knew that children could have ET, and 3/4 did not know of a celebrity or historical figure with ET. Hence, lack of knowledge and misconceptions were common.Public knowledge of the existence and features of ET (...) Public Knowledge and Attitude toward Essential Tremor: A Questionnaire Survey Public awareness of and attitude toward disease is an important issue for patients. Public awareness of essential tremor (ET) has never been studied.We administered a 10-min, 31-item questionnaire to 250 consecutive enrollees. These included three samples carefully chosen to have a potential range of awareness of ET: 100 individuals ascertained from a vascular disease clinic, 100 individuals from a general neurology

2016 Frontiers in neurology

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