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Alcohol Tremor

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181. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary Full Text available with Trip Pro

relevant to this guideline, was conducted between February and August 2015. Key search words included but were not limited to the following: adherence; aerobic; alcohol intake; ambulatory care; antihypertensive: agents, drug, medication, therapy; beta adrenergic blockers; blood pressure: arterial, control, determination, devices, goal, high, improve, measurement, monitoring, ambulatory; calcium channel blockers; diet; diuretic agent; drug therapy; heart failure: diastolic, systolic; hypertension: white

2017 American Heart Association

182. Opioid Use and Opioid Use Disorder in Pregnancy

as a risk factor for hepatitis C and other virus transmission in a group of pregnant women with hepatitis C ( ). Regular, long-term use of any opioid leads to predictable physiological dependence, which results in symptoms of withdrawal upon discontinuation of the drug. Typical symptoms of opioid withdrawal include generalized pain, muscle pain, nausea, diarrhea, sweating, rhinorrhea, tearing, dilated pupils, tremor, gooseflesh, restlessness, and anxiety. With short-acting opioids, such as heroin (...) , withdrawal symptoms may develop within 4–6 hours of use, peak at 1–3 days, and gradually subside over a period of 5–7 days. For long-acting opioids, such as methadone, withdrawal symptoms usually begin within 24–36 hours of use and may last for several weeks. Unlike alcohol withdrawal, opioid withdrawal is rarely associated with severe morbidity and can be readily treated. Effects of Opioid Use on Pregnancy and Pregnancy Outcome The safety of opioids during early pregnancy has been evaluated in a number

2017 American College of Obstetricians and Gynecologists

183. 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Hea Full Text available with Trip Pro

with alcohol consumption, preinfarction angina, anterior infarct location, and complete coronary occlusion at the time of coronary angiography. In a select group of patients undergoing primary PCI in a clinical trial, 5.7% developed sustained VT or VF, with two thirds of these events occurring prior to the end of the catheterization, and 90% within 48 hours from the procedure. VT or VF after primary PCI was associated with lower blood pressure, higher heart rate, poor coronary flow at the end

2017 American Heart Association

184. AIM Clinical Appropriateness Guidelines for Interventional Pain Management

of an isolated pars defect ? Use of MBB or RFN at the level of a posterolateral fusion or posterior instrumentation ? Use of non-thermal RF modalities for facet joint denervation, including chemical, low grade thermal energy ( 1°C), skin color changes or asymmetry o Sudomotor/edema: Evidence of edema, sweating changes, or sweating asymmetry o Motor/trophic: Evidence of decreased range of motion, motor dysfunction (eg, weakness, tremor, dystonia), or trophic changes (eg, hair, nail, skin) o No other diagnosis (...) questionnaires and/or psychological testing) that confirms no evidence of an inadequately controlled mental health problem (e.g., alcohol or drug dependence, depression, psychosis) that would negatively impact the success of a spinal cord stimulator or contraindicate its placement. Dorsal column stimulation may be indicated for the relief of chronic intractable neuropathic pain of the trunk and/or limbs in the following conditions: ? Lumbosacral arachnoiditis as documented by high levels of protein

2017 AIM Specialty Health

185. Staff and Associate Specialist Grade Handbook (Third Edition)

• Long sleeves when inappropriate • Frequent toilet breaks • Nasal rubbing/itching or drowsiness after ‘top-up’ breaks • Nasal discharge, yawning, tears, pallor, sweating, piloerection and feeling cold if withdrawing • Alcohol on the breath • Poor anaesthetic charts – particularly altered or (deliberately) illegible entries. Similarly, uncharacteristically poor handwriting (alcohol withdrawal tremor) • Using techniques without narcotics, falsifying charts and diverting drugs for own use • Offering (...) disease [1], and is classified accordingly with other chronic illnesses. Unfortunately society’s attitude has not changed significantly and addiction is still a rather taboo subject. For the purpose of this chapter, the terms ‘addiction’ and ‘dependence’ are used interchangeably. Further and more detailed information on some aspects of addiction and its management can be found on the AAGBI website and in Drug and Alcohol Abuse amongst Anaesthetists. Out of each cohort at medical school, approximately

2017 Association of Anaesthetists of GB and Ireland

186. Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia

activity, education and intellectual engagement, social engagement, alcohol, smoking, and substance abuse, medications, and vitamins. Interventions represent one way to establish the veracity of risk factors. If changing a putative risk factor changes the cognitive course, it will be seen as more salient. Interventions have been developed to prevent or treat chronic diseases and to modify risk factors and protective factors. Multidomain interventions address multiple risk factors simultaneously

2017 Effective Health Care Program (AHRQ)

188. Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia

activity, education and intellectual engagement, social engagement, alcohol, smoking, and substance abuse, medications, and vitamins. Interventions represent one way to establish the veracity of risk factors. If changing a putative risk factor changes the cognitive course, it will be seen as more salient. Interventions have been developed to prevent or treat chronic diseases and to modify risk factors and protective factors. Multidomain interventions address multiple risk factors simultaneously

2017 Effective Health Care Program (AHRQ)

189. Rifaximin for preventing episodes of overt hepatic encephalopathy

or an increase in Conn and asterixis score of 1 grade each for people who entered the study with a Conn score of 0. The asterixis score measures worsening neurological impairment in terms of flapping tremor, which is determined by the person extending their arms with wrists flexed backwards and fingers open for 30 seconds or more. This is also measured on a scale of 0 to 4, with higher scores indicating more flapping motions. Key secondary outcomes included: time to first hepatic encephalopathy-related

2015 National Institute for Health and Clinical Excellence - Technology Appraisals

190. Bipolar disorder: assessment and management

functioning declines significantly treatment adherence is poor the person develops intolerable or medically important side effects from medication comorbid alcohol or drug misuse is suspected the person is considering stopping any medication after a period of relatively stable mood a woman with bipolar disorder is pregnant or planning a pregnancy. Monitoring ph Monitoring physical health ysical health 1.2.10 Develop and use practice case registers to monitor the physical and mental health of people (...) changes identify personal recovery goals. 1.3.3 T ake into account the possibility of differential diagnoses including Bipolar disorder: assessment and management (CG185) © NICE 2019. All rights reserved. Subject to Notice of rights ( conditions#notice-of-rights). Page 19 of 46schizophrenia spectrum disorders, personality disorders, drug misuse, alcohol-use disorders, attention deficit hyperactivity disorder and underlying physical disorders such as hypo

2014 National Institute for Health and Clinical Excellence - Clinical Guidelines

191. Multiple sclerosis in adults: management

and swallowing, and these are referenced where appropriate. Many of the interventions used in a rehabilitation setting to alleviate symptoms such as tremor, weakness, cardiorespiratory fitness, sensory loss, visual problems (apart from oscillopsia), and secondary complications of immobility such as deconditioning and contractures have not been covered because these are beyond the scope of the guideline. Many of these problems are complex and need individual assessment and management strategies (...) healthcare professionals with expertise in specific areas of the review if needed. 1.6.3 T ailor the comprehensive review to the needs of the person with MS assessing: MS symptoms: mobility and balance including falls need for mobility aids including wheelchair assessment use of arms and hands muscle spasms and stiffness tremor bladder (see Urinary incontinence in neurological disease NICE clinical Multiple sclerosis in adults: management (CG186) © NICE 2018. All rights reserved. Subject to Notice

2014 National Institute for Health and Clinical Excellence - Clinical Guidelines

192. Premature ejaculation: dapoxetine

such as heart failure, significant ischaemic heart disease or history of syncope; a history of mania or severe depression; moderate and severe hepatic impairment; and concomitant treatment with monoamine oxidase inhibitors, thioridazine, SSRIs, tricyclic antidepressants or other herbal/medicinal products with serotonergic effects and potent CYP3A4 inhibitors. The summary of product characteristics states that men should be advised not to use dapoxetine in combination with recreational drugs or alcohol (...) and safety of dapoxetine have not been established in men aged 65 years and over (summary of product characteristics). Very common (greater than 1 in 10 men) adverse reactions reported in the summary of product characteristics are dizziness, headache and nausea. Common (between 1 in 100 and 1 in 10 men) adverse reactions reported include anxiety, agitation, insomnia, somnolence, abnormal dreams, tremor, paraesthesia, blurred vision, tinnitus, erectile dysfunction, decreased libido, increased blood

2014 National Institute for Health and Clinical Excellence - Advice

193. Briviact - brivaracetam

. Packaging is also described by dosage form as described in section 6.5 of the SmPC. Film-coated tablets: Tablet core: croscarmellose sodium, lactose monohydrate, betadex, anhydrous lactose and magnesium stearate. Film coating: polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, talc and iron oxides (E172) – black (25, 75 and 100 mg tablets), red (50 and 75 mg tablets) and yellow (25, 50, 75 and 100 mg tablets). Tablets are available in PVC/PCTFE/alu blisters and PVC/PCTFE/alu perforated unit dose (...) the affinity and binding properties of BRV to the SV2A protein as well as the effect of BRV on various voltage-gated ion channel currents and ligand-gated receptor currents. Secondary pharmacodynamics has been investigated in pharmacology models beyond epilepsy including animal models of pain, essential tremor, mania and migraine. For safety pharmacology, effects of BRV on the central nervous system (CNS), cardiovascular system and respiratory system, as well as the gastrointestinal system, were

2016 European Medicines Agency - EPARs

194. Odefsey (emtricitabine / rilpivirine / tenofovir alafenamide) - HIV-1

and povidone. Film-coating: macrogol, polyvinyl alcohol, talc, titanium dioxide (E171) and iron oxide black (E172). The product is packaged in high density polyethylene (HDPE) bottle with a polypropylene (PP) continuous- thread, child-resistant cap, lined with an induction activated aluminium foil liner. Each bottle contains silica gel desiccant and a polyester coil as described in section 6.5 of the SmPC. Assessment report EMA/335723/2016 Page 11/120 2.2.2. Active substance Emtricitabine (FTC

2016 European Medicines Agency - EPARs

195. Neofordex - dexamethasone. To treat adults with multiple myeloma

]-dexamethasone, 41% and 44% of the administered radioactivity was detected in urine at 0-24 hours and 0-96 hours, respectively (Van Leeuwen, 2010). In dogs intravenously administered 1 mg/kg dexamethasone alcohol or dexamethasone 21-isonicotinate, the half time of elimination was 120 to 140 minutes (Van Leeuwen, 2010). In pigs, subcutaneously administered [1,2- 3 H]-dexamethasone-21-trimethylacetate, less than 1% of total plasma radioactivity was extractable as unchanged [ 3 H]-dexamethasone-21-acetate at 4

2016 European Medicines Agency - EPARs

196. Wakix - pitolisant. Narcolepsy

hydrochloride) and 18 mg of pitolisant (equivalent to 20 mg of pitolisant hydrochloride) as active substance. Other ingredients are: Tablet core: microcrystalline cellulose, crospovidone Type A, talc, magnesium stearate, colloidal anhydrous silica. Coating: polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, and talc. The product is available in high density polyethylene (HDPE) bottle with a tamper evident, child- resistant, polypropylene screw cap fitted with silica gel desiccant. 2.2.2. Active (...) findings of muscular hypotony and sedation, and changes in state of mood at 30 mg/kg and above. Trace of tremors was observed at 60 mg/kg and minimal appearance of opisthotonus and few tonic and clonic convulsions at 100 mg/kg. Furthermore, pitolisant was shown to display a pro- convulsant activity at doses higher than 30 mg/kg, p.o. in the pentylenetetrazole-induced convulsion mouse model. Overall, pitolisant induced a dose-dependent increase in central excitation leading to the appearance

2016 European Medicines Agency - EPARs

197. Deep brain stimulation in mental health

in neurological disorders such as Parkinson’s disease, intractable tremor and dystonia, and is less commonly used or under investigation for other disorders such as epilepsy and Tourette’s syndrome. 2-7 The indication for the use of DBS determines the placement of the individual stimulating electrodes. For many indications there are a number of neuroanatomical targets that provide therapeutic relief. For example, three DBS implantation sites have been shown to be clinically efficacious for Parkinson’s disease (...) applied to the NA. 58 All four patients appeared to achieve a substantial improvement in symptoms of anorexia with an average follow-up period of more than three years. Addiction A small literature has also explored the potential use of DBS for the treatment of addictive disorders, primarily with a focus on stimulation of the NA reward system. There have been a number of individual case reports suggesting remission of symptoms in the treatment of alcohol and heroin addiction 59, 60 and a small case

2016 Sax Institute Evidence Check

198. Pain Management

daily or non-steroidal anti-inflammatory drug (NSAID) (if not contraindicated - see section"Adjuvant therapies" below)) ± other adjuvant Consider reducing paracetamol dose to 500mg four times daily when poor nutritional status, low weight (< 50kg), hepatic impairment and/or chronic alcohol abuse (check local policy for paracetamol and NSAIDs if patient receiving chemotherapy). Inadequate pain relief Step 2: mild to moderate pain weak opioid Codeine 30 to 60mg four times daily or dihydrocodeine 30 (...) ) caution in cardiovascular disease. gabapentin (side effects: sedation, tremor, confusion; reduce dose if renal impairment). Corticosteroids : dexamethasone 16mg daily for raised intracranial pressure. 8mg daily for neuropathic pain; 4 to 8mg/day for liver capsule pain. Give in the morning; reduce to lowest effective dose. Consider PPI. Monitor blood glucose. TENS, nerve block, radiotherapy, surgery, bisphosphonates, (specialist use) and skeletal or smooth muscle relaxants. Opioid toxicity – seek

2016 Scottish Palliative Care Guidelines

199. British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum

. The data are confounded because mothers with bipolar disorder were more often smokers, over- weight and alcohol or substance abusers, regardless of treatment, when compared to unaffected mothers (Boden et al., 2012a). Both untreated and treated women with bipolar disorder had increased risks of Caesarean delivery, instrumental delivery and a non-spontaneous start to delivery, as well as preterm delivery (8% vs 5%) compared to controls. There was no significant dif- ference between groups for very (...) to the offspring is similar whether it is the mother or father who smoked during pregnancy and this was not as a result of passive smoking on the part of the mother (Langley et al., 2012). This suggests that genetic rather than intrauterine effects may be causal.8 Journal of Psychopharmacology Alcohol misuse/dependence. Alcohol consumption in preg- nancy is associated with miscarriage, preterm birth, low birth- weight and developmental delays encompassed within the umbrella term of Fetal Alcohol Spectrum

2017 British Association for Psychopharmacology

200. Ofev - nintedanib

to record signs of toxicity or mortalities. Oral administration of BIBF 1120 ES at doses of 3, 20 and 100 mg/kg (as base) produced no significant test article-induced changes in the behaviour or physiological state of rats. One female rat treated with 20 mg/kg BIBF 1120 exhibited slight tremor and piloerection at 30 and 90 minutes and slight tremor at 150 minutes post treatment. As only one animal at the intermediate dose level exhibited these mild changes, it was considered to be incidental

2015 European Medicines Agency - EPARs

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