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Adrenal Mass

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61. Mass Spectrometry-Based Adrenal and Peripheral Venous Steroid Profiling for Subtyping Primary Aldosteronism. Full Text available with Trip Pro

Mass Spectrometry-Based Adrenal and Peripheral Venous Steroid Profiling for Subtyping Primary Aldosteronism. Differentiating patients with primary aldosteronism caused by aldosterone-producing adenomas (APAs) from those with bilateral adrenal hyperplasia (BAH), which is essential for choice of therapeutic intervention, relies on adrenal venous sampling (AVS)-based measurements of aldosterone and cortisol. We assessed the utility of LC-MS/MS-based steroid profiling to stratify patients (...) with primary aldosteronism.Fifteen adrenal steroids were measured by LC-MS/MS in peripheral and adrenal venous plasma from AVS studies for 216 patients with primary aldosteronism at 3 tertiary referral centers. Ninety patients were diagnosed with BAH and 126 with APAs on the basis of immunoassay-derived adrenal venous aldosterone lateralization ratios.Among 119 patients confirmed to have APAs at follow-up, LC-MS/MS-derived lateralization ratios of aldosterone normalized to cortisol, dehydroepiandrosterone

2016 Clinical Chemistry

63. Adrenal masses: A urological perspective Full Text available with Trip Pro

Adrenal masses: A urological perspective Adrenal masses have become increasingly common due to widespread use of sectional imaging. Urologists are commonly faced with management decisions in patients with adrenal masses. Systemic review of available literature related to surgical adrenal disease was performed to summarise the most pertinent information related to adrenal masses, diagnostic evaluation and surgical treatment. Detailed hormonal evaluation of adrenal disease was not included, being (...) part of endocrinological rather than urological practice. Adrenal masses exhibit a wide spectrum of presentation and pathology, and treatment requires different surgical techniques. Full understanding of the pathology and management of such masses should be completely familiar to practicing urologists.

2016 Arab journal of urology

64. Carotid Intima-Media Thickness as the Cardiometabolic Risk Indicator in Patients with Nonfunctional Adrenal Mass and Metabolic Syndrome Screening Full Text available with Trip Pro

Carotid Intima-Media Thickness as the Cardiometabolic Risk Indicator in Patients with Nonfunctional Adrenal Mass and Metabolic Syndrome Screening Our purpose was to show the association of adrenal incidentaloma and metabolic syndrome in consideration of the studies and to detect the increase in the carotid intima-media thickness which is regarded as the precessor of atherosclerosis.Eighty-one patients who were diagnosed with adrenal mass were included in the study. Hormonal evaluation, insulin (...) rezistance measurement with the HOMA-IR and 1-mg DST were performed of all patients. The patients were classified as follows: mass size <3 cm (K1) and mass size of at least 3 cm (K2). Echocardiography and carotid intima-media thickness of the patients were measured using B-mode ultrasound. Thirty-three healthy individuals were enrolled as the control group.Mass size of 64.19% K1, while mass size of the remainder (35.81%) K2 was calculated. Five of the patients with adrenal mass were detected to have

2016 Medical science monitor : international medical journal of experimental and clinical research

65. Radiographic Characteristics of Adrenal Masses in Oncologic Patients Full Text available with Trip Pro

Radiographic Characteristics of Adrenal Masses in Oncologic Patients We aimed to assess the usefulness of pre-contrast Hounsfield unit (HU) and mass size on computed tomography to differentiate adrenal mass found incidentally in oncologic patients.From 2000 to 2012, 131 oncologic patients with adrenal incidentaloma were reviewed retrospectively. Receiver operating characteristic (ROC) curves were applied to determine the optimal cut-off value of the mean HU and size for detecting adrenal (...) metastasis.The median age was 18 years, and 80 patients were male. The initial mass size was 18 mm, and 71 (54.2%) of these were on the left side. A bilateral adrenal mass was found in 11 patients (8.4%). Biochemically functional masses were observed in 9.2% of patients. Thirty-six out of 119 patients with nonfunctional masses underwent adrenalectomy, which revealed metastasis in 13. The primary cancers were lung cancer (n=4), renal cell carcinoma (n=2), lymphoma (n=2), hepatocellular carcinoma (n=2), breast

2016 Endocrinology and Metabolism

66. Bilateral adrenal masses: a single-centre experience Full Text available with Trip Pro

Bilateral adrenal masses: a single-centre experience Bilateral adrenal masses may have aetiologies like hyperplasia and infiltrative lesions, besides tumours. Hyperplastic and infiltrative lesions may have coexisting hypocortisolism. Bilateral tumours are likely to have hereditary/syndromic associations. The data on clinical profile of bilateral adrenal masses are limited.To analyse clinical, biochemical and radiological features, and management outcomes in patients with bilateral adrenal (...) masses.Retrospective analysis of 70 patients with bilateral adrenal masses presenting to a single tertiary care endocrine centre from western India (2002-2015).The most common aetiology was pheochromocytoma (40%), followed by tuberculosis (27.1%), primary adrenal lymphoma (PAL) (10%), metastases (5.7%), non-functioning adenomas (4.3%), primary bilateral macronodular adrenal hyperplasia (4.3%), and others (8.6%). Age at presentation was less in patients with pheochromocytoma (33 years) and tuberculosis (41 years

2016 Endocrine connections

67. Management of Adrenal Masses Full Text available with Trip Pro

Management of Adrenal Masses An adrenal mass can be either symptomatic or asymptomatic in the form of adrenal incidentalomas (AIs) in up to 8 % in autopsy and 4 % in imaging series. Once a diagnosis of adrenal mass is made, we need to differentiate whether it is functioning or nonfunctioning, benign, or malignant. In this article, we provide a literature review of the diagnostic workup including biochemical evaluation and imaging characteristics of the different pathologies. We also discuss (...) the surgical strategies with laparoscopy as the mainstay with partial adrenalectomy in select cases and adrenalectomy in large masses. Follow-up protocol of AIs and adrenocortical carcinoma is also discussed.

2016 Indian journal of surgical oncology

68. Adrenal mass in a patient with tetralogy of Fallot: beyond expected Full Text available with Trip Pro

Adrenal mass in a patient with tetralogy of Fallot: beyond expected 28210477 2018 11 13 2008-5117 8 4 2016 Journal of cardiovascular and thoracic research J Cardiovasc Thorac Res Adrenal mass in a patient with tetralogy of Fallot: beyond expected. 190-191 10.15171/jcvtr.2016.38 Martínez-Quintana Efrén E Cardiology Service, Insular-Materno Infantil University Hospital, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain. Rodríguez-González Fayna F Dr. Negrín University

2016 Journal of cardiovascular and thoracic research

69. Young male with left adrenal mass Full Text available with Trip Pro

Young male with left adrenal mass 27432826 2017 02 17 2018 11 13 1757-790X 2016 2016 Jul 15 BMJ case reports BMJ Case Rep Young male with left adrenal mass. 10.1136/bcr-2016-215669 bcr2016215669 Meshikhes Abdul-Wahed Nasir AW Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia. Abdel Gawad Wael M WM Department of Surgical Oncology, National Cancer Institute, Cairo, Egypt. Al-Saeed Jamal Youssef JY Department of Endocrinology, King Fahad Specialist Hospital, Dammam, Saudi (...) Arabia. eng Case Reports Journal Article 2016 07 15 England BMJ Case Rep 101526291 1757-790X IM Adrenal Gland Neoplasms diagnostic imaging pathology surgery Adrenal Glands diagnostic imaging surgery Adrenocortical Carcinoma diagnostic imaging pathology surgery Adult Fatal Outcome Humans Image-Guided Biopsy Magnetic Resonance Imaging Male Tomography, X-Ray Computed Ultrasonography, Interventional Young Adult 2016 7 20 6 0 2016 7 20 6 0 2017 2 18 6 0 epublish 27432826 bcr-2016-215669 10.1136/bcr-2016

2016 BMJ case reports

70. Incidentally Solitary, Synchronous, Metastatic Left Adrenal Mass From Colon Cancer Full Text available with Trip Pro

Incidentally Solitary, Synchronous, Metastatic Left Adrenal Mass From Colon Cancer The authors report the case of a 63-year-old man who underwent an open adrenalectomy for a synchronous, malignant, metastatic left adrenal tumor and a total colectomy for T3N0M1 (stage 4) primary, malignant colon cancer. Two polypoid lesions, one measuring 40 mm × 30 mm × 30 mm and the other measuring 20 mm × 10 mm × 10 mm, were found in the ascending colon and rectosigmoid (RS) junction, respectively (...) , and a synchronous, malignant, left adrenal gland lesion measuring 70 mm × 50 mm × 30 mm was incidentally found on abdominal computed tomography scan. Histological examination revealed a metastatic, necrotic adenocarcinoma of the left adrenal mass, an adenocarcinoma of the cecal mass, and an adenomatous polyp (tubulovillous type) of the smallest polypoid lesion in RS junction that had invaded deeply into the submucosal layer. The patient recovered uneventfully, and his condition is now stable, with no evidence

2016 Annals of coloproctology

71. Prof. Rajeev Kumar: adrenal masses Full Text available with Trip Pro

Prof. Rajeev Kumar: adrenal masses 27652238 2016 09 21 2017 02 24 2223-4691 5 4 2016 Aug Translational andrology and urology Transl Androl Urol Prof. Rajeev Kumar: adrenal masses. 630-1 10.21037/tau.2016.07.07 Gao Lucine M LM eng News China Transl Androl Urol 101581119 2223-4683 The author has no conflicts of interest to declare. 2016 9 22 6 0 2016 9 22 6 0 2016 9 22 6 1 ppublish 27652238 10.21037/tau.2016.07.07 tau-05-04-630 PMC5001993

2016 Translational andrology and urology

72. Ectopic Thyroid Tissue in the Adrenal Gland Mimicking a Pheochromocytoma Full Text available with Trip Pro

Ectopic Thyroid Tissue in the Adrenal Gland Mimicking a Pheochromocytoma Ectopic thyroid tissue in the adrenal gland (ETTAG) usually presents as a well-circumscribed cystic mass on a CT scan. However, the MRI features of ETTAG are incompletely understood. We report a case of ectopic thyroid tissue in the adrenal gland, which demonstrates findings similar to those of a pheochromocytoma on the MRI.

2017 Journal of endourology case reports

73. Salivary Cortisol and Cortisone After Low-Dose Corticotropin Stimulation in the Diagnosis of Adrenal Insufficiency Full Text available with Trip Pro

Salivary Cortisol and Cortisone After Low-Dose Corticotropin Stimulation in the Diagnosis of Adrenal Insufficiency Basal and poststimulation salivary cortisol and cortisone levels can be useful in the diagnosis of adrenal insufficiency. However, little is known about the optimal cutoffs and performance characteristics of these tests.To derive the cutoff values and study the performance characteristics of salivary cortisol and salivary cortisone in the diagnosis of adrenal (...) insufficiency.Prospective study in a regional hospital in Hong Kong from January 2014 to September 2015.Fifty-six Chinese healthy volunteers and 171 patients suspected of having adrenal insufficiency.All participants underwent low-dose short Synacthen test (LDSST) with intravenous injection of 1 μg of tetracosactide (Synacthen 1-24). Serum cortisol, salivary cortisol and cortisone levels were measured at baseline and 30 and 60 minutes afterward.Using the reference cutoff (mean - 2 standard deviations of post-LDSST peak

2017 Journal of the Endocrine Society

74. Maffucci Syndrome Associated With Adrenocorticotropic Hormone–Independent Bilateral Macronodular Adrenal Hyperplasia Full Text available with Trip Pro

patient presenting a history suggestive of secondary arterial hypertension and typical features of Maffucci syndrome (multiple hemangiomas and enchondromas), which were unrecognized over the previous 3 decades. Given that endocrine diseases are common causes of secondary arterial hypertension and are often associated with Maffucci syndrome, a comprehensive diagnostic workup was performed, revealing the presence of large bilateral adrenal masses (70 mm right, 35 mm left) and autonomous cortisol (...) endocrine diseases and malignancies. Among them, unilateral cortical adrenal masses have been previously described, but to our knowledge, this is the first reported case of Maffucci syndrome associated with primary bilateral macronodular adrenal hyperplasia. Additional studies are needed to establish the etiopathological link between these 2 entities and, more in general, between Maffucci syndrome and endocrine diseases, but possible common genetic alterations may be suggested.

2017 Journal of the Endocrine Society

75. Renal mass and localized renal cancer: AUA guideline.

findings suggest metastasis or direct invasion of the adrenal gland. ( Clinical Principle ) In patients undergoing surgical excision of a renal mass, a minimally invasive approach should be considered when it would not compromise oncologic, functional and perioperative outcomes. ( Expert Opinion ) Pathologic evaluation of the adjacent renal parenchyma should be performed after PN or RN to assess for possible intrinsic renal disease, particularly for patients with CKD or risk factors for developing CKD (...) Renal mass and localized renal cancer: AUA guideline. Renal mass and localized renal cancer: AUA guideline. | National Guideline Clearinghouse success fail JUN 09 2017 2018 2019 14 Apr 2018 - 12 Jul 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving copies of rapidly dying or deleted websites for the sake of history and digital heritage. The group is 100% composed

2017 National Guideline Clearinghouse (partial archive)

76. Renal Mass and Localized Renal Cancer

should perform adrenalectomy if imaging and/or intraoperative findings suggest metastasis or direct invasion of the adrenal gland. (Clinical Principle) In patients undergoing surgical excision of a renal mass, a minimally invasive approach should be considered when it would not compromise oncologic, functional and perioperative outcomes. (Expert Opinion) Pathologic evaluation of the adjacent renal parenchyma should be performed after PN or RN to assess for possible intrinsic renal disease (...) and aggressive tumor biology. Contrast-enhanced abdominal imaging (CT or MRI) best characterizes the mass, provides information regarding renal morphology (of the affected and unaffected kidney), assesses extrarenal tumor spread (venous invasion or regional lymphadenopathy) and evaluates the adrenal glands and other abdominal organs for visceral metastases. Patients with CKD and GFR less than 45 ml/min/1.73m 2 should receive contrast with caution as iodinated contrast agents can transiently or permanently

2017 American Urological Association

77. Management of Small Renal Masses

Management of Small Renal Masses Management of Small Renal Masses: American Society of Clinical Oncology Clinical Practice Guideline | Journal of Clinical Oncology Search in: Menu Article Tools ASCO SPECIAL ARTICLE Article Tools OPTIONS & TOOLS COMPANION ARTICLES April, 01 2017 May, 10 2017 ARTICLE CITATION DOI: 10.1200/JCO.2016.69.9645 Journal of Clinical Oncology - published online before print January 17, 2017 PMID: Management of Small Renal Masses: American Society of Clinical Oncology (...) , Levine Cancer Institute, Charlotte, NC; William Lowrance, University of Utah, Huntsman Cancer Institute, Salt Lake City, UT; R. Houston Thompson, Mayo Clinic, Rochester, MN; and Robert Uzzo, Fox Chase Cancer Center, Philadelphia, PA. A.F. and P.R. were Expert Panel co-chairs. Abstract Section: Purpose To provide recommendations for the management options for patients with small renal masses (SRMs). Methods By using a literature search and prospectively defined study selection, we sought systematic

2017 American Society of Clinical Oncology Guidelines

78. Insulin-Mediated Diseases: Adrenal Mass and Polycystic Ovary Syndrome. (Abstract)

Insulin-Mediated Diseases: Adrenal Mass and Polycystic Ovary Syndrome. Adrenal incidentalomas (AIs) and polycystic ovary syndrome (PCOS) have often been associated with compensatory hyperinsulinemia and insulin resistance (IR). The link between these diseases and IR may be changes in hormone secretions that provoke IR and in turn promote the growth of adrenal gland masses and/or ovarian cysts through compensatory hyperinsulinemia. Copyright © 2015 Elsevier Ltd. All rights reserved.

2015 Trends in Endocrinology and Metabolism

79. Castleman’s disease imitating adrenal mass in the retroperitoneal area Full Text available with Trip Pro

Castleman’s disease imitating adrenal mass in the retroperitoneal area Castleman's disease (CD) is a non-clonal lymph node hyperplasia, mostly seen in the mediastinum. It has various clinical and pathological outcomes. There are different treatments because of its rare occurance and heterogenity. We present 2 cases which were referred to our clinic as retroperitoneal mass and diagnosed as CD after surgical resection.

2015 Canadian Urological Association Journal

80. Adrenal Mass Causing Secondary Hypertension. (Abstract)

Adrenal Mass Causing Secondary Hypertension. Most hypertensive patients have essential (primary) hypertension; only 5% to 10% have a secondary cause. Two clinical characteristics suggestive of secondary hypertension are early onset (< 30 years of age) and severe hypertension (>180/110 mm Hg). When faced with these findings, clinicians should consider a secondary cause of hypertension.A 22-year-old woman being evaluated for asthma exacerbation in the emergency department was noted to have severe (...) persistent hypertension. Additional evaluation revealed severe hypokalemia, metabolic alkalosis, and hypernatremia. The patient was admitted to the hospital for blood pressure management, electrolyte replacement, and further evaluation of presumed hyperaldosteronism. Diagnostic imaging revealed a large adrenal mass. Surgical resection was performed, leading to a diagnosis of hyperaldosteronism caused by adrenal carcinoma. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Secondary hypertension is far

2015 Journal of Emergency Medicine

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