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Adrenal Mass

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41. Adrenal masses: A urological perspective (PubMed)

Adrenal masses: A urological perspective Adrenal masses have become increasingly common due to widespread use of sectional imaging. Urologists are commonly faced with management decisions in patients with adrenal masses. Systemic review of available literature related to surgical adrenal disease was performed to summarise the most pertinent information related to adrenal masses, diagnostic evaluation and surgical treatment. Detailed hormonal evaluation of adrenal disease was not included, being (...) part of endocrinological rather than urological practice. Adrenal masses exhibit a wide spectrum of presentation and pathology, and treatment requires different surgical techniques. Full understanding of the pathology and management of such masses should be completely familiar to practicing urologists.

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2016 Arab journal of urology

42. MANAGEMENT OF ENDOCRINE DISEASE: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses - a systematic review and meta-analysis. (PubMed)

MANAGEMENT OF ENDOCRINE DISEASE: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses - a systematic review and meta-analysis. Adrenal masses are incidentally discovered in 5% of CT scans. In 2013/2014, 81 million CT examinations were undertaken in the USA and 5 million in the UK. However, uncertainty remains around the optimal imaging approach for diagnosing malignancy. We aimed to review the evidence on the accuracy of imaging tests for differentiating malignant (...) screening 5469 references and 525 full-text articles. Studies evaluated the accuracy of CT (n=16), MRI (n=15), and FDG-PET (n=9) and were generally small and at high or unclear risk of bias. Only 19 studies were eligible for meta-analysis. Limited data suggest that CT density >10HU has high sensitivity for detection of adrenal malignancy in participants with no prior indication for adrenal imaging, that is, masses with ≤10HU are unlikely to be malignant. All other estimates of test performance are based

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2016 European journal of endocrinology / European Federation of Endocrine Societies

43. Bilateral adrenal masses: a single-centre experience (PubMed)

Bilateral adrenal masses: a single-centre experience Bilateral adrenal masses may have aetiologies like hyperplasia and infiltrative lesions, besides tumours. Hyperplastic and infiltrative lesions may have coexisting hypocortisolism. Bilateral tumours are likely to have hereditary/syndromic associations. The data on clinical profile of bilateral adrenal masses are limited.To analyse clinical, biochemical and radiological features, and management outcomes in patients with bilateral adrenal (...) masses.Retrospective analysis of 70 patients with bilateral adrenal masses presenting to a single tertiary care endocrine centre from western India (2002-2015).The most common aetiology was pheochromocytoma (40%), followed by tuberculosis (27.1%), primary adrenal lymphoma (PAL) (10%), metastases (5.7%), non-functioning adenomas (4.3%), primary bilateral macronodular adrenal hyperplasia (4.3%), and others (8.6%). Age at presentation was less in patients with pheochromocytoma (33 years) and tuberculosis (41 years

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2016 Endocrine connections

44. Carotid Intima-Media Thickness as the Cardiometabolic Risk Indicator in Patients with Nonfunctional Adrenal Mass and Metabolic Syndrome Screening (PubMed)

Carotid Intima-Media Thickness as the Cardiometabolic Risk Indicator in Patients with Nonfunctional Adrenal Mass and Metabolic Syndrome Screening Our purpose was to show the association of adrenal incidentaloma and metabolic syndrome in consideration of the studies and to detect the increase in the carotid intima-media thickness which is regarded as the precessor of atherosclerosis.Eighty-one patients who were diagnosed with adrenal mass were included in the study. Hormonal evaluation, insulin (...) rezistance measurement with the HOMA-IR and 1-mg DST were performed of all patients. The patients were classified as follows: mass size <3 cm (K1) and mass size of at least 3 cm (K2). Echocardiography and carotid intima-media thickness of the patients were measured using B-mode ultrasound. Thirty-three healthy individuals were enrolled as the control group.Mass size of 64.19% K1, while mass size of the remainder (35.81%) K2 was calculated. Five of the patients with adrenal mass were detected to have

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2016 Medical science monitor : international medical journal of experimental and clinical research

45. Radiographic Characteristics of Adrenal Masses in Oncologic Patients (PubMed)

Radiographic Characteristics of Adrenal Masses in Oncologic Patients We aimed to assess the usefulness of pre-contrast Hounsfield unit (HU) and mass size on computed tomography to differentiate adrenal mass found incidentally in oncologic patients.From 2000 to 2012, 131 oncologic patients with adrenal incidentaloma were reviewed retrospectively. Receiver operating characteristic (ROC) curves were applied to determine the optimal cut-off value of the mean HU and size for detecting adrenal (...) metastasis.The median age was 18 years, and 80 patients were male. The initial mass size was 18 mm, and 71 (54.2%) of these were on the left side. A bilateral adrenal mass was found in 11 patients (8.4%). Biochemically functional masses were observed in 9.2% of patients. Thirty-six out of 119 patients with nonfunctional masses underwent adrenalectomy, which revealed metastasis in 13. The primary cancers were lung cancer (n=4), renal cell carcinoma (n=2), lymphoma (n=2), hepatocellular carcinoma (n=2), breast

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2016 Endocrinology and Metabolism

46. Adrenal Mass

Adrenal Mass Adrenal Mass Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Adrenal Mass Adrenal Mass Aka: Adrenal Mass , Adrenal (...) Incidentaloma II. Epidemiology Incidental Adrenal Mass found on up to 3-4% of s or MRIs Incidental Adrenal Masses found in 20% of autopsies III. Differential Diagnosis of Incidental Adrenal Mass Adrenal Adenoma (51%) Non-functioning adenoma Functioning adenoma Metastatic cancer (31%) Adrenal Carcinoma (1-4%) Adrenal (4%) (4%) Adrenal Hyperplasia (2%) (2%) Myelolipoma (2%) IV. Labs Screening Consider plasma free metanephrines (in all patients) s 24-hour (VMA) Screening (in all patients) Screening

2018 FP Notebook

47. Mass Spectrometry-Based Adrenal and Peripheral Venous Steroid Profiling for Subtyping Primary Aldosteronism. (PubMed)

Mass Spectrometry-Based Adrenal and Peripheral Venous Steroid Profiling for Subtyping Primary Aldosteronism. Differentiating patients with primary aldosteronism caused by aldosterone-producing adenomas (APAs) from those with bilateral adrenal hyperplasia (BAH), which is essential for choice of therapeutic intervention, relies on adrenal venous sampling (AVS)-based measurements of aldosterone and cortisol. We assessed the utility of LC-MS/MS-based steroid profiling to stratify patients (...) with primary aldosteronism.Fifteen adrenal steroids were measured by LC-MS/MS in peripheral and adrenal venous plasma from AVS studies for 216 patients with primary aldosteronism at 3 tertiary referral centers. Ninety patients were diagnosed with BAH and 126 with APAs on the basis of immunoassay-derived adrenal venous aldosterone lateralization ratios.Among 119 patients confirmed to have APAs at follow-up, LC-MS/MS-derived lateralization ratios of aldosterone normalized to cortisol, dehydroepiandrosterone

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2016 Clinical Chemistry

48. Associations between hypothalamic-pituitary-adrenal axis function and peak bone mass at 20years of age in a birth cohort. (PubMed)

Associations between hypothalamic-pituitary-adrenal axis function and peak bone mass at 20years of age in a birth cohort. In older adults, high-normal circulating cortisol levels are associated with lower bone mass, but relationships between hypothalamic-pituitary-adrenal axis function and peak bone mass in young adults have not been examined. We studied 411 male and 390 female participants in the Western Australia Pregnancy Cohort (Raine) Study. At 18years of age, participants underwent (...) . In females, there were no significant relationships between baseline cortisol or TSST responses and BMC or BMD in covariate-adjusted analyses. We conclude that in young males (but not females), higher circulating cortisol at the baseline of the stress test and an anticipatory responder pattern on the TSST are associated with lower total body bone mass. Copyright © 2016 Elsevier Inc. All rights reserved.

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2016 Bone

49. Adrenal mass in a patient with tetralogy of Fallot: beyond expected (PubMed)

Adrenal mass in a patient with tetralogy of Fallot: beyond expected 28210477 2018 11 13 2008-5117 8 4 2016 Journal of cardiovascular and thoracic research J Cardiovasc Thorac Res Adrenal mass in a patient with tetralogy of Fallot: beyond expected. 190-191 10.15171/jcvtr.2016.38 Martínez-Quintana Efrén E Cardiology Service, Insular-Materno Infantil University Hospital, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain. Rodríguez-González Fayna F Dr. Negrín University

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2016 Journal of cardiovascular and thoracic research

50. Management of Adrenal Masses (PubMed)

Management of Adrenal Masses An adrenal mass can be either symptomatic or asymptomatic in the form of adrenal incidentalomas (AIs) in up to 8 % in autopsy and 4 % in imaging series. Once a diagnosis of adrenal mass is made, we need to differentiate whether it is functioning or nonfunctioning, benign, or malignant. In this article, we provide a literature review of the diagnostic workup including biochemical evaluation and imaging characteristics of the different pathologies. We also discuss (...) the surgical strategies with laparoscopy as the mainstay with partial adrenalectomy in select cases and adrenalectomy in large masses. Follow-up protocol of AIs and adrenocortical carcinoma is also discussed.

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2016 Indian journal of surgical oncology

52. Contemporary minimally invasive surgery for adrenal masses: It's not all about (Pure) laparoscopy. (PubMed)

Contemporary minimally invasive surgery for adrenal masses: It's not all about (Pure) laparoscopy. 27801536 2018 03 14 2018 03 14 1464-410X 119 2 2017 02 BJU international BJU Int. Contemporary minimally invasive surgery for adrenal masses: it's not all about (pure) laparoscopy. 201-203 10.1111/bju.13701 Pavan Nicola N Urology Clinic, Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy. Derweesh Ithaar I Department of Urology, UC San Diego Health System, La (...) , Cleveland Clinic, Cleveland, OH, USA. Porpiglia Francesco F Division of Urology, Department of Oncology, University of Turin 'San Luigi' Hospital, Orbassano, Italy. Autorino Riccardo R Urology Institute, University Hospitals, Case Western Reserve University, Cleveland, OH, USA. eng Letter Review 2016 11 21 England BJU Int 100886721 1464-4096 IM Adrenal Gland Neoplasms mortality pathology surgery Adrenalectomy adverse effects methods Disease-Free Survival Female Forecasting Humans Laparoscopy standards

2016 BJU international

53. LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening (SPECTROSPOT)

LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening (SPECTROSPOT) LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening (SPECTROSPOT) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening (SPECTROSPOT) (SPECTROSPOT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before

2018 Clinical Trials

54. Severe bilateral adrenal hemorrhages in a newborn complicated by persistent adrenal insufficiency (PubMed)

process.Risk factors for adrenal hemorrhage include fetal macrosomia, traumatic vaginal delivery and critical acidemia.Signs of adrenal hemorrhage include jaundice, flank mass, skin discoloration or scrotal hematoma.Adrenal insufficiency often is a transient process when related to adrenal hemorrhage.Severe adrenal hemorrhages can occur in the absence of symptoms.Though rare, persistent adrenal insufficiency may occur in extremely severe cases of bilateral adrenal hemorrhage.Consider adrenal hemorrhage (...) Severe bilateral adrenal hemorrhages in a newborn complicated by persistent adrenal insufficiency Bilateral adrenal hemorrhages rarely occur during the neonatal period and are often associated with traumatic vaginal deliveries. However, the adrenal gland has highly regenerative capabilities and adrenal insufficiency typically resolves over time. We evaluated a newborn female after experiencing fetal macrosomia and a traumatic vaginal delivery. She developed acidosis and acute renal injury

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2018 Endocrinology, diabetes & metabolism case reports

55. Juxta-adrenal schwannoma presenting as a giant adrenal tumor: A case report and a literature review (PubMed)

Juxta-adrenal schwannoma presenting as a giant adrenal tumor: A case report and a literature review Retroperitoneal schwannomas (RS) are rare, benign tumors that originate in the neural sheath. Juxta-adrenal schwannomas may be misdiagnosed with giant adrenal tumors. This article reports the case of a RS that presented as an asymptomatic adrenal mass in a 50 Y.O female.An abdominal ultrasound of our asymptomatic patient showed right adrenal lesion of 9 cm of diameter. Endocrinological evaluation (...) was negative. The patient was considered to have a non-secreting right adrenal mass confirmed by adrenal scan. We began a right laparoscopic trans peritoneal adrenalectomy, but when we discovered intra operatively that the wall of the IVC and the renal vein were very adherent to the mass which had a lot of small vessels that were bleeding, we converted to open surgery that allowed us to remove the mass safely. The operative time was 200 min, the blood loss was 850 cc and the patient was discharged

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2018 International journal of surgery case reports

56. Primary Bilateral Non-Hodgkin's Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses (PubMed)

Primary Bilateral Non-Hodgkin's Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease. We present a case of a 62-year-old woman with a history of mild/moderate hereditary spherocytosis with a well-compensated baseline haemoglobin, who presented with rapidly progressive symptomatic anaemia. During the diagnostic workup, imaging (...) revealed bilateral large adrenal masses and she was later diagnosed with diffuse large B-cell non-Hodgkin's lymphoma (DLBCL), with the adrenal glands being the dominant site of the disease. The patient was started on systemic chemotherapy, but her disease progressed with neurological involvement which responded to second-line therapy. Her adrenal disease however was refractory to further therapy.

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2015 Case reports in medicine

57. 11-Oxygenated Androgens are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency. (PubMed)

), ages 2 to 67 years (median, 15 years), seen in a tertiary referral center.We correlated a mass-spectrometry panel of 23 steroids, obtained before first morning medication, with bone age advancement (children), adrenal volume (adults), testicular adrenal rest tumors (TART), hirsutism, menstrual disorders, and pituitary hormones.Total adrenal volume correlated positively with 18 steroids, most prominently 21-deoxycortisol and four 11-oxygenated-C19 (11oxC19) steroids: 11β-hydroxyandrostenedione (...) 11-Oxygenated Androgens are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency. Patients with 21-hydroxylase deficiency (21OHD) have long-term complications, resulting from poor disease control and/or glucocorticoid overtreatment. Lack of optimal biomarkers has made it challenging to tailor therapy and predict long-term outcomes.To identify biomarkers of disease control and long-term complications in 21OHD.Cross-sectional study of 114 patients (70 males

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2017 Journal of Clinical Endocrinology and Metabolism

58. Massive adrenal incidentalomas and late diagnosis of congenital adrenal hyperplasia in prostate cancer (PubMed)

. Elementary school photographs demonstrated precocious puberty. Physical examination revealed palpable abdominal (adrenal) masses. Abiraterone and glucocorticoid treatment was commenced with excellent suppression of testosterone. Genetic testing revealed a mutation in CYP21A2 confirming 21-hydroxylase-deficient congenital adrenal hyperplasia (CAH). Association of large myelolipomas with CAH has been reported in the literature. Our case highlights the importance of considering CAH in patients with non (...) Massive adrenal incidentalomas and late diagnosis of congenital adrenal hyperplasia in prostate cancer In a 61-year-old Caucasian male with prostate cancer, leuprolide and bicalutamide failed to suppress the androgens. He presented to endocrinology with persistently normal testosterone and incidental massive (up to 18 cm) bilateral adrenal myelolipomas on CT scan. Blood test did not reveal metanephrine excess. The patient was noted to have short stature (151 cm) and primary infertility

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2017 Endocrinology, diabetes & metabolism case reports

59. Persistent Primary Aldosteronism Despite Iatrogenic Adrenal Hemorrhage After Adrenal Vein Sampling (PubMed)

Persistent Primary Aldosteronism Despite Iatrogenic Adrenal Hemorrhage After Adrenal Vein Sampling Before surgery for primary aldosteronism (PA), localization is evaluated with adrenal vein sampling (AVS). A 56-year-old Japanese woman had a right adrenal mass, hypokalemia, and a high aldosterone/renin ratio. Stress tests confirmed the diagnosis of PA. Subsequently, preoperative AVS was performed and right adrenal hemorrhage (AH) occurred unexpectedly. Because hypertension persisted (...) , laparoscopic right adrenalectomy was performed. Postoperatively, the blood pressure was normalized. Pathological examination revealed an adrenal cortical adenoma largely unaffected by necrosis and hemorrhage. Previous reports have also indicated that AH may not ameliorate PA. We discussed the clinical progress of AH and the measures to prevent causing AH.

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2017 Journal of clinical medicine research

60. Angiomyolipoma of the Adrenal Gland: A Case Presentation and a Review of Adrenal Lipomatous Tumors (PubMed)

. Differential diagnosis of adrenal masses should include lipomatous tumors, as operative considerations and prognoses can be drastically altered. (...) Angiomyolipoma of the Adrenal Gland: A Case Presentation and a Review of Adrenal Lipomatous Tumors Angiomyolipoma (AML) is a typically benign renal tumor derived from mesenchymal tissue. Extrarenal occurrences of AML are possible, but the adrenals are an exceedingly rare site. To date, a total of 4 cases of adrenal AML have been documented in the English literature.1-3 We present a case of right-sided adrenal AML found in a patient who initially presented with right-sided flank pain

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2017 Urology case reports

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