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Adrenal Mass

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21. Obesity in children with congenital adrenal hyperplasia in the Minnesota cohort: importance of adjusting body mass index for height-age Full Text available with Trip Pro

Obesity in children with congenital adrenal hyperplasia in the Minnesota cohort: importance of adjusting body mass index for height-age To evaluate obesity and overweight in children with congenital adrenal hyperplasia (CAH) and associations with glucocorticoids, fludrocortisone and disease control. Adjusting body mass index-for-height-age (BMIHA ) percentile is proposed to correct misclassification of obese/overweight status in CAH children with advanced bone age and tall-for-age (...) stature.Longitudinal.One hundred and ninety-four children with CAH seen from 1970 to 2013: 124 salt wasting (SW); 70 simple virilizing (SV); 102 females.Body mass index (BMI) end-points were overweight (85-94 percentile) and obese (≥95 percentile).Approximately 50% of the children had at least one BMI measurement ≥95 percentile and about 70% had at least one ≥85 percentile. Using BMIHA percentiles, obesity incidence decreased slightly in SW children (47-43%) and markedly in SV children (50-33%); however, overweight

2017 Clinical endocrinology

22. Right retroperitoneal splenosis presenting as an adrenal mass Full Text available with Trip Pro

Right retroperitoneal splenosis presenting as an adrenal mass 29134175 2019 02 26 2214-4420 16 2018 Jan Urology case reports Urol Case Rep Right retroperitoneal splenosis presenting as an adrenal mass. 44-45 10.1016/j.eucr.2017.08.006 Felice Michael M Vattikuti Urology Institute, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA. Tourojman Mouafak M Vattikuti Urology Institute, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA. Rogers Craig C Vattikuti (...) Urology Institute, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA. eng Case Reports 2017 10 26 United States Urol Case Rep 101626357 2214-4420 Adrenal mass Splenosis Tc-99 heat-damaged autologous red blood cell scan 2017 08 03 2017 08 18 2017 11 15 6 0 2017 11 15 6 0 2017 11 15 6 1 epublish 29134175 10.1016/j.eucr.2017.08.006 S2214-4420(17)30167-5 PMC5671415 South Med J. 2007 Jun;100(6):589-93 17591312 Clin Radiol. 1994 Feb;49(2):115-7 8124888 ANZ J Surg. 2012 Oct;82(10 ):758

2017 Urology case reports

23. A Rare Differential Diagnosis of an Adrenal Mass: A Case Report Full Text available with Trip Pro

A Rare Differential Diagnosis of an Adrenal Mass: A Case Report Ten years after his last treatment for diffuse large B-cell lymphoma, a seemingly healthy, 64-year-old man presented for his lymphoma-related follow-up. Ultrasound revealed an impressive tumor in the right adrenal gland. Due to recurrent cancer therapies in the past, this seemed highly suspicious of a second malignancy, such as primary adrenal carcinoma. Surprisingly, histology disclosed a very different but rare cause

2017 Case reports in oncology

24. Large Unilateral Adrenal Mass with Surrounding Brown Fat: A Case Report Full Text available with Trip Pro

Large Unilateral Adrenal Mass with Surrounding Brown Fat: A Case Report Pheochromocytomas are rare tumors derived from chromaffin cells located in the adrenal and extra adrenal tissues. Pheochromocytomas are diagnosed biochemically and localized using different imaging modalities. The definitive management is surgical resection. Brown adipose tissues are normally present during fetal development, with regression over time. Brown adipose tissues are thermogenic and usually located in the neck

2017 Cureus

25. A Giant Adrenal Mass in a Super Obese Patient Full Text available with Trip Pro

A Giant Adrenal Mass in a Super Obese Patient Giant pheochromocytomas (Pheo) are rare entities requiring clinical suspicion coupled with strategic diagnostic evaluation to confirm the diagnosis. The majority of cases are discovered incidentally. The diagnosis consists of biochemical evaluation and imaging study to localize the mass. Pathological examination confirms the diagnosis. The female patient in this case report presented with chest pain, palpitation of three weeks duration and was found (...) on evaluation to have an abdominal mass concerning for pheochromocytoma. She was treated with surgical resection. The pheo measured 20.5 x 18 x 10 cm and weighed 2,582 grams. Pathological examination confirmed the diagnosis of pheochromocytoma.

2017 Cureus

26. Reference intervals for plasma concentrations of adrenal steroids measured by LC-MS/MS: Impact of gender, age, oral contraceptives, body mass index and blood pressure status Full Text available with Trip Pro

Reference intervals for plasma concentrations of adrenal steroids measured by LC-MS/MS: Impact of gender, age, oral contraceptives, body mass index and blood pressure status Mass spectrometric-based measurements of the steroid metabolome have been introduced to diagnose disorders featuring abnormal steroidogenesis. Defined reference intervals are important for interpreting such data.Liquid chromatography-tandem mass spectrometry was used to establish reference intervals for 16 steroids (...) phase, menopause and oral contraceptive use. Progesterone was higher in females than males, but most other steroids were higher in males than females and almost all declined with advancing age. Using models that corrected for age and gender, body mass index showed weak negative relationships with corticosterone, 21-deoxycortisol, cortisol, cortisone, testosterone, progesterone, 17-hydroxyprogesterone and 11-deoxycorticosterone, but a positive relationship with 18-hydroxycortisol. Hypertensives

2017 Clinica chimica acta; international journal of clinical chemistry

27. Adrenal mass of unusual etiology: Ewing sarcoma in a young man Full Text available with Trip Pro

Adrenal mass of unusual etiology: Ewing sarcoma in a young man Ewing sarcoma and peripheral primitive neuroectodermal tumor belong to the Ewing sarcoma (ES) family of tumors originating from a primitive neural tube. We report a 31-year-old man who was admitted to the urology clinic with complaints of fever, nausea, and dysuria. A right-sided adrenal mass was detected during ultrasonography. The lesion was then evaluated with magnetic resonance imaging, which showed areas of necrosis amid (...) heterogeneous solid areas. Whole body scan with 2-deoxy-2-[fluorine-18]fluoro-D-glucose integrated with computed tomography and bone scan studies showed pulmonary and osseous metastatic foci. The mass and right kidney were removed by an open approach. An immunohistochemical and molecular workup enabled the diagnosis of ES. The patient also underwent radiotherapy and chemotherapy. The patient remained in fairly good health during the 18-month follow-up period, but showed progression of all metastatic foci

2017 Radiology Case Reports

28. Management of Adrenal Masses in Patients with Beckwith-Wiedemann Syndrome Full Text available with Trip Pro

Management of Adrenal Masses in Patients with Beckwith-Wiedemann Syndrome Beckwith-Wiedemann syndrome (BWS) is a genetic overgrowth and cancer predisposition syndrome, associated with both benign and malignant adrenal findings. Literature review and an institutional case series elucidate the wide spectrum of adrenal findings in BWS patients. The altered expression of the 11p15 region is likely related to adrenal gland hyperplasia and growth dysregulation. Given the absence of guidelines (...) for managing adrenal findings in BWS, we propose a systematic approach to adrenal findings in BWS patients, to allow for maximum detection of potentially malignant pathology without posing additional risk to patients.© 2017 Wiley Periodicals, Inc.

2017 Pediatric blood & cancer

29. Performance of 18F-FDG PET/CT in the characterization of adrenal masses in non-cancer patients: A prospective study. Full Text available with Trip Pro

Performance of 18F-FDG PET/CT in the characterization of adrenal masses in non-cancer patients: A prospective study. Few prospective studies have evaluated the role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the characterization of adrenal masses.To assess the performance of 18F-FDG PET/CT in the malignancy diagnosis of adrenal masses in noncancer patients.Prospective multicenter study.The study population consisted of 87 patients (87 adrenal (...) masses) referred to endocrine surgeons: 56 with mass diameter ≥40 mm and 31 with a diameter <40 mm and of indeterminate nature based on unenhanced and washout CT attenuation densities. Fourteen patients had hypercortisolism. Adrenal masses were characterized by 18F-FDG PET/CT. Histology was the gold standard for the diagnosis of malignancy. In the absence of pathological proof (n = 23), the nature of the lesion was based on the 12-month imaging follow-up.Fifteen adrenal masses were classified

2017 Journal of Clinical Endocrinology and Metabolism

30. Minimally invasive resection of adrenal masses in infants and children: results of a European multi-center survey. (Abstract)

Minimally invasive resection of adrenal masses in infants and children: results of a European multi-center survey. Minimal access adrenal surgery (MAAS) for adrenal pathologies is the standard for many pediatric surgical centers. However, the literature offers few reports and minimal evidence from small case series. The aim of this study was to evaluate the outcomes of pediatric MAAS through a multi-center data analysis.Pediatric patients who underwent MAAS between January 2002 and December (...) 2013 were retrospectively included. Data analysis was conducted using Spss software (Welch's t-test, X-square, Fisher tests, multiple regression model).Six European centers participated, 68 patients were included with mean age of 5.2 years (2 months-16 years). Lesion volume was of 18.1 cc (0.78-145.6), with a mean diameter of 2.8 cm (1.1-6.5). Localization was 50% left-sided masses, 45.6% right-side masses, and 4.4% bilateral. Histological examination revealed 36 neuroblastomas, 15 adenomas, nine

2017 Surgical endoscopy

31. Adrenal mass: insight into pathogenesis and a common link with insulin resistance. Full Text available with Trip Pro

Adrenal mass: insight into pathogenesis and a common link with insulin resistance. Adrenal mass (AM) is a common incidental finding detected during radiological investigations with an estimated incidence of 4%. Subjects with AM do not show any physical signs of adrenal hormonal excess, although they are often insulin resistant. Interestingly, apparently nonfunctioning AMs are often associated with a high prevalence of insulin resistance (IR) and metabolic syndrome. However, it is unclear (...) whether AM develops from a primary IR and compensatory hyperinsulinemia or whether IR is only secondary to the slight cortisol hypersecretion by AM. Further, the degree of IR has been directly reported to correlate to the size of AM, thus allowing one to hypothesize that compensatory hyperinsulinemia to IR could be mitogenic on the adrenal cortex acting through the activation of insulin and insulinlike growth factor 1 receptors. Thus, the aim of the present article is to review the current evidence

2017 Endocrinology

32. Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumours Full Text available with Trip Pro

: Research Article Online Publication Date: 01 Aug 2016 Copyright: © 2016 European Society of Endocrinology 2016 Free access By definition, an adrenal incidentaloma is an asymptomatic adrenal mass detected on imaging not performed for suspected adrenal disease. In most cases, adrenal incidentalomas are nonfunctioning adrenocortical adenomas, but may also represent conditions requiring therapeutic intervention (e.g. adrenocortical carcinoma, pheochromocytoma, hormone-producing adenoma or metastasis (...) autonomous cortisol secretion, formerly called ‘subclinical’ Cushing’s syndrome?; (C) Who should have surgical treatment and how should it be performed?; (D) What follow-up is indicated if the adrenal incidentaloma is not surgically removed? Selected recommendations: (i) At the time of initial detection of an adrenal mass establishing whether the mass is benign or malignant is an important aim to avoid cumbersome and expensive follow-up imaging in those with benign disease. (ii) To exclude cortisol

2016 European Society of Endocrinology

33. Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency Full Text available with Trip Pro

other methods ( e.g. , genotyping) to improve the positive predictive value of congenital adrenal hyperplasia screening. (1|⊕⊕○○) Technical remark: Laboratories utilizing liquid chromatography–tandem mass spectrometry should participate in an appropriate quality assurance program. Additionally, clinicians should realize that immunoassays lead to more false-positive results. Thus, if laboratory resources do not include liquid chromatography–tandem mass spectrometry, a cosyntropin stimulation test (...) newborn screens for congenital adrenal hyperplasia we recommend referral to pediatric endocrinologists (if regionally available) and evaluation by cosyntropin stimulation testing as needed. (1|⊕⊕⊕○) 3.2 In symptomatic individuals past infancy, we recommend screening with an early-morning (before 8 am ) baseline serum 17-hydroxyprogesterone measurement by liquid chromatography–tandem mass spectrometry. (1|⊕⊕⊕○) 3.3 In individuals with borderline 17-hydroxyprogesterone levels, we recommend obtaining

2018 Pediatric Endocrine Society

34. Rare defects in Adrenal Steroidogenesis Full Text available with Trip Pro

Rare defects in Adrenal Steroidogenesis MECHANISMS IN ENDOCRINOLOGY: Rare defects in adrenal steroidogenesis in: European Journal of Endocrinology Volume 179 Issue 3 Year 2018 This site uses cookies, tags, and tracking settings to store information that help give you the very best browsing experience. If you don't change your settings, we'll assume you're happy with this. Google Translate to save searches and organize your favorite content. Not registered? Search Recently viewed (1) MECHANISMS (...) IN ENDOCRINOLOGY: Rare defects in adrenal steroidogenesis in Author: View More View Less 1 Department of Pediatrics, Center for Reproductive Sciences, and Institute of Human Genetics, University of California, San Francisco, California, USA Correspondence should be addressed to W L Miller; Email: wlmlab@ucsf.edu DOI: Page(s): R125–R141 Volume/Issue: Article Type: Review Article Online Publication Date: Sep 2018 Copyright: © 2018 European Society of Endocrinology 2018 Free access Congenital adrenal hyperplasia

2018 Pediatric Endocrine Society

35. Glucocorticoid activity of adrenal steroid precursors in untreated patients with congenital adrenal hyperplasia. (Abstract)

Glucocorticoid activity of adrenal steroid precursors in untreated patients with congenital adrenal hyperplasia. We describe clinical features and biochemical characteristics of a unique population of severely affected untreated patients with congenital adrenal hyperplasia (CAH) from an Indonesian population, with proven cortisol deficiency but without clinical signs of cortisol deficiency. We evaluated the in vitro glucocorticoid activity of all relevant adrenal steroid precursors occurring (...) in CAH patients.Cross sectional cohort study and translational research.Adrenal steroid precursor concentrations before and 60 minutes after ACTH administration of 24 untreated CAH patients (3-46years) with proven cortisol deficiency (< 500nmol/L post-ACTH) measured by liquid chromatography tandem-mass spectrometry (LC-MS/MS) were compared to 6 control patients (Mann-Whitney U test). Glucocorticoid receptor (GR) activation was determined by dual-luciferase assays in human embryonic kidney cells

2019 Journal of Clinical Endocrinology and Metabolism

36. Adrenal Mass

Adrenal Mass Adrenal Mass Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Adrenal Mass Adrenal Mass Aka: Adrenal Mass , Adrenal (...) Incidentaloma II. Epidemiology Incidental Adrenal Mass found on up to 3-4% of s or MRIs Incidental Adrenal Masses found in 20% of autopsies III. Differential Diagnosis of Incidental Adrenal Mass Adrenal Adenoma (51%) Non-functioning adenoma Functioning adenoma Metastatic cancer (31%) Adrenal Carcinoma (1-4%) Adrenal (4%) (4%) Adrenal Hyperplasia (2%) (2%) Myelolipoma (2%) IV. Labs Screening Consider plasma free metanephrines (in all patients) s 24-hour (VMA) Screening (in all patients) Screening

2018 FP Notebook

37. Chemical shift imaging for evaluation of adrenal masses: a systematic review and meta-analysis

Chemical shift imaging for evaluation of adrenal masses: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address

2018 PROSPERO

38. Characterization of adrenal masses by using FDG PET: a systematic review and meta-analysis of diagnostic test performance

Characterization of adrenal masses by using FDG PET: a systematic review and meta-analysis of diagnostic test performance Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

39. MKSAP: 62-year-old woman with a left adrenal mass

MKSAP: 62-year-old woman with a left adrenal mass Biochemical testing is needed to identify functional incidentalomas MKSAP: 62-year-old woman with a left adrenal mass | | March 24, 2018 1 Shares Test your medicine knowledge with the , in partnership with the . A 62-year-old woman is evaluated for an incidentally discovered left adrenal mass. Two weeks ago, the patient was evaluated in the emergency department for diffuse abdominal pain and vomiting. A CT scan was obtained that was normal (...) except for the adrenal mass. Three hours after presentation to the emergency department, the pain resolved spontaneously. Her medical history is significant for diet-controlled type 2 diabetes mellitus diagnosed 1 year ago and osteoporosis diagnosed 4 years ago. Her only medication is alendronate. On physical examination, temperature is 37.0 °C (98.6 °F), blood pressure is 120/80 mm Hg, and pulse rate is 70/min. BMI is 26. The remainder of the physical examination is normal. Laboratory evaluation

2018 KevinMD blog

40. A case of adrenal Cushing’s syndrome with bilateral adrenal masses Full Text available with Trip Pro

A case of adrenal Cushing’s syndrome with bilateral adrenal masses A functional lesion in corticotrophin (ACTH)-independent Cushing's syndrome is difficult to distinguish from lesions of bilateral adrenal masses. Methods for distinguishing these lesions include adrenal venous sampling and (131)I-6β-iodomethyl-19-norcholesterol ((131)I-NP-59) scintigraphy. We present a case of a 29-year-old Han Chinese female patient with a history of hypercholesterolaemia and polycystic ovary syndrome. She (...) presented with a 6month history of an 8kg body weight gain and gradual rounding of the face. Serial examinations revealed loss of circadian rhythm of cortisol, elevated urinary free-cortisol level and undetectable ACTH level (<5pg/mL). No suppression was observed in both the low- and high-dose dexamethasone suppression tests. Adrenal computed tomography revealed bilateral adrenal masses. Adrenal venous sampling was performed, and the right-to-left lateralisation ratio was 14.29. The finding from adrenal

2016 Endocrinology, diabetes & metabolism case reports

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