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Acute Vision Loss

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121. Australian guidelines for the treatment of acute stress disorder and posttraumatic stress disorder

Australian guidelines for the treatment of acute stress disorder and posttraumatic stress disorder Acute Stress Disorder & Posttraumatic Stress Disorder Promoting recovery after trauma Australian Guidelines for the Treatment of© Phoenix Australia - Centre for Posttraumatic Mental Health, 2013 ISBN Print: 978-0-9752246-0-1 ISBN Online: 978-0-9752246-1-8 This work is copyright. Apart from any use as permitted under the Copyright Act 1968, no part may be reproduced by any process without prior (...) Mental Health. Australian Guidelines for the Treatment of Acute Stress Disorder and Posttraumatic Stress Disorder. Phoenix Australia, Melbourne, Victoria. Legal disclaimer This document is a general guide to appropriate practice, to be followed only subject to the practitioner’s judgement in each individual case. The guidelines are designed to provide information to assist decision making and are based on the best information available at the date of publication. In recognition of the pace

2013 Clinical Practice Guidelines Portal

122. Altered regional homogeneity in patients with unilateral acute open-globe injury: a resting-state functional MRI study (PubMed)

in the right cerebellum posterior lobe/lingual gyrus, left superior temporal gyrus/inferior frontal gyrus, left inferior frontal gyrus, left posterior cingulate cortex/precuneus, and left precentral operculum. However, there was no relationship between the observed mean ReHo values of the different brain areas and the behavioral performance.Acute OGI may cause dysfunction in many brain regions, which may reflect the underlying pathologic mechanisms of acute vision loss in OGI patients. (...) Altered regional homogeneity in patients with unilateral acute open-globe injury: a resting-state functional MRI study To investigate the underlying regional homogeneity (ReHo) brain activity changes in patients with unilateral acute open-globe injury (OGI) and their relationship with their clinical features.In total, 18 patients with acute OGI (16 males and two females) and 18 healthy controls (HCs; 16 males and two females) closely matched in age, sex, and education status participated

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2016 Neuropsychiatric disease and treatment

123. Acute Mountain Sickness Symptoms Depend on Normobaric versus Hypobaric Hypoxia (PubMed)

in NH (namely, feeling sick and shortness of breath) compared to HH (characterized most by feeling faint, appetite loss, light headedness, and dim vision). However, the differences were not detected using the LLS. These results suggest that during the initial hours of exposure (1) AMS in HH may be a qualitatively different experience than in NH and (2) NH and HH may not be interchangeable environments. (...) Acute Mountain Sickness Symptoms Depend on Normobaric versus Hypobaric Hypoxia Acute mountain sickness (AMS), characterized by headache, nausea, fatigue, and dizziness when unacclimatized individuals rapidly ascend to high altitude, is exacerbated by exercise and can be disabling. Although AMS is observed in both normobaric (NH) and hypobaric hypoxia (HH), recent evidence suggests that NH and HH produce different physiological responses. We evaluated whether AMS symptoms were different in NH

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2016 BioMed research international

124. S100A8 promotes migration and infiltration of inflammatory cells in acute anterior uveitis (PubMed)

S100A8 promotes migration and infiltration of inflammatory cells in acute anterior uveitis Uveitis, the pathologic condition of inflammation of the uvea, frequently leads to severe vision loss and blindness. S100A8 is a calcium-binding protein which mainly expresses in granulocytes and monocytes and plays a prominent role in the regulation of inflammatory processes and immune response. Here, we determined the role of S100A8-positive cells in acute anterior uveitis (AAU) and keratitis. In rat

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2016 Scientific reports

125. Treatment Trial for Acute Central Serous Chorioretinopathy

to Brief Summary: Central serous chorioretinopathy (CSC) is a relatively frequent eye disease in younger patients. It is characterized by serous detachment of the neurosensory retina with or without serous detachment of the retinal pigment epithelium (RPE), which can cause vision drop, image distortion, loss of color and contrast vision. Although nonfoveal focal leakage can be treated with traditional laser photocoagulation, but it has the side effects of causing RPE atrophy, scotoma, or secondary CNV (...) Treatment Trial for Acute Central Serous Chorioretinopathy Treatment Trial for Acute Central Serous Chorioretinopathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment Trial for Acute Central Serous

2016 Clinical Trials

126. Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management

Hours Postoperatively [ Time Frame: 24 hours ] Will assess for known symptoms of gabapentin postoperatively at 24 hours. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction Number of Patient With Gabapentin Adverse Effects at 2 Weeks Postoperatively [ Time Frame: 2 weeks ] Will assess for known symptoms of gabapentin postoperatively at 2 (...) weeks. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction Narcotic Use at 2 Weeks Postop [ Time Frame: 2 weeks ] Assessment of the amount of narcotic use postoperatively at 2 weeks. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents Subjective Pain at 2 Weeks Postop [ Time Frame: 2 weeks ] Assessment

2016 Clinical Trials

127. Prevalence of anti-retinal antibodies in Acute Zonal Occult Outer Retinopathy (AZOOR): a comprehensive review of 25 cases. (PubMed)

antibodies by Western blot analysis. MainOutcome Measures: Clinical presentation, best-corrected visual acuity (BCVA), fundus abnormalities, visual field defects, ffERG changes, and presence of antiretinal antibodies.Sixteen patients (64%) presented with photopsias, 56% (14/25) with night blindness, and 56% (14/25) with loss of peripheral vision. Sixty-four percent (16/25) of cases were bilateral. All patients demonstrated retinal vascular attenuation, optic nerve head pallor, and mottling of retinal (...) Prevalence of anti-retinal antibodies in Acute Zonal Occult Outer Retinopathy (AZOOR): a comprehensive review of 25 cases. To perform a comprehensive review and to investigate the presence and role of autoimmune antibodies in 25 cases of acute zonal occult outer retinopathy (AZOOR) identified using the classification originally proposed by J. Donald Gass.Observational case series.Setting: Institutional.Twenty-five patients were identified by characteristic symptoms (abrupt onset of photopsias

2016 American Journal of Ophthalmology

128. Perioperative Antibiotics to Prevent Acute Endophthalmitis after Ophthalmic Surgery: A Systematic Review and Meta-Analysis. (PubMed)

Perioperative Antibiotics to Prevent Acute Endophthalmitis after Ophthalmic Surgery: A Systematic Review and Meta-Analysis. Post-operative endophthalmitis is a rare and dreaded complication in ophthalmic operations because it often induces irreparable vision loss. Although many ophthalmological studies aimed at reducing the rate of endophthalmitis have been performed around the world, controversy continues to surround some issues, including the choice of antimicrobials and their route

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2016 PloS one

129. Acute Red Eye

inflammation V. Indications: Ophthalmology Consultation Symptoms suggesting need for emergent or urgent ophthalmology evaluation Moderate to severe and Irregular pupil l involvement Blurred vision with photophobia Acute Conditions prompting emergent or urgent ophthalmology evaluation (HSV) ( ) Acute angle Other conditions where routine ophthalmology evaluation should be considered VI. Evaluation Evaluate Normal Vision Decreased Vision Acute Loss of Vision disease Determine involved Focal hyperemia suggests (...) , Eye Redness , Bloodshot Eye II. History Timing Acute, subacute or chronic Associated symptoms or Blurred Vision Photophobia Associated Conditions Systemic symptoms ( s or ) Recent illness or infection III. Exam: Eye (always) Consider first if light sensitive Delay only in cases of (irrigation precedes acuity exam) Visual fields by confrontation Defect suggests l, or CNS injury Free and painful movement in all directions exam Evaluate for pupil size and reactivity l Exam (typically with ) stain

2018 FP Notebook

130. Effect of Phenytoin on the Ganglion Cell Inner Plexiform Layer and Visual Field in Patients With an Acute Optic Neuritis

days since onset visual loss Exclusion Criteria: Contraindication or known allergy to Phenytoin Use of a calcium channel or sodium channel blocker in the past 2 months Corticosteroid use in the past 2 months Pregnancy Significant cardiac, renal or liver abnormalities Prior clinical episode of optic neuritis in either eye Bilateral acute optic neuritis Known ocular or neurological conditions or abnormalities other than refractive error that impair visual function Refractive error of greater than +5 (...) Effect of Phenytoin on the Ganglion Cell Inner Plexiform Layer and Visual Field in Patients With an Acute Optic Neuritis Effect of Phenytoin on the Ganglion Cell Inner Plexiform Layer and Visual Field in Patients With an Acute Optic Neuritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2016 Clinical Trials

131. Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial. (PubMed)

Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial. Acute demyelinating optic neuritis, a common feature of multiple sclerosis, can damage vision through neurodegeneration in the optic nerve and in its fibres in the retina. Inhibition of voltage-gated sodium channels is neuroprotective in preclinical models. In this study we aimed to establish whether sodium-channel inhibition with phenytoin is neuroprotective in patient (...) with acute optic neuritis.We did a randomised, placebo-controlled, double-blind phase 2 trial at two UK academic hospitals in London and Sheffield. Patients with acute optic neuritis aged 18-60 years, presenting within 2 weeks of onset, with visual acuity of 6/9 or worse, were randomly assigned (1:1) by minimisation via a web-based service to oral phenytoin (maintenance dose 4 mg/kg per day if randomised before or on July 16, 2013, and 6 mg/kg per day if randomised on or after July 17, 2013) or placebo

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2016 The Lancet. Neurology

132. Extramedullary Relapse of Acute Myelogenous Leukemia Presenting as a Large Serous Retinal Detachment (PubMed)

transplant, presented with acute vision loss. Ophthalmic workup revealed a large, unilateral, bullous, serous retinal detachment. Ultimately, he underwent subretinal fluid biopsy, which was found to be positive for leukemic blast cells. Cytologic markers matched his initial bone marrow biopsy, and therefore were diagnostic of extramedullary AML relapse.Leukemia can cause various ophthalmic manifestations. Autopsy studies suggest that choroidal infiltration is relatively common, but clinical progression (...) Extramedullary Relapse of Acute Myelogenous Leukemia Presenting as a Large Serous Retinal Detachment To describe the rare presentation of a large, unilateral, serous retinal detachment as an extramedullary manifestation of acute myelogenous leukemia (AML) recurrence without bone marrow or central nervous system involvement after more than 1 year of follow-up.Case report.A teenage patient with AML, previously treated with multiple courses of systemic chemotherapy, radiation, and bone marrow

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2016 Ocular oncology and pathology

133. Acute multifocal hemorrhagic retinal vasculitis in a child: a case report. (PubMed)

Acute multifocal hemorrhagic retinal vasculitis in a child: a case report. Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult individuals. The reported treatment options for Acute Multifocal Hemorrhagic Retinal Vasculitis are oral (...) corticosteroids, intravitreal ganciclovir and laser photocoagulation or vitrectomy. We report a child with Acute Multifocal Hemorrhagic Retinal Vasculitis who was treated with aggressive immunosuppressive therapy resulting in a favorable visual outcome.A retrospective case report of a 10-year-old African American girl who developed unilateral Acute Multifocal Hemorrhagic Retinal Vasculitis, which later on progressed bilaterally. We conducted a review of the clinical, laboratory and photographic records

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2016 BMC Ophthalmology

134. Cross-sectional study of the retinal nerve fiber layer thickness at 7 years after an acute episode of unilateral primary acute angle closure. (PubMed)

. The peripapillary RNFL thickness was correlated with age, gender, presenting intraocular pressure (IOP), time to laser iridotomy, time to cataract extraction, follow-up duration, as well as the last IOP, vertical cup-to-disc ratio (CDR), and vision. The fellow uninvolved eye was used as a proxy comparison of RNFL loss in the attack eye. In 40 eligible patients, the mean age was 68.3 ± 8.7 years with a male-to-female ratio of 1:7. The mean presenting IOP was 49.2 ± 14.0 mm Hg and the time from presentation (...) Cross-sectional study of the retinal nerve fiber layer thickness at 7 years after an acute episode of unilateral primary acute angle closure. The purpose of this article is to investigate the long-term retinal nerve fiber layer (RNFL) status and determinants of RNFL thinning after an episode of unilateral primary acute angle closure (AAC). This cross-sectional study analyzed the medical records of consecutive patients with a single episode of unilateral AAC from 1999 to 2009 in Hong Kong

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2015 Medicine

135. Reversal of Severe Visual Loss from Syphilitic Chorioretinitis Following Penicillin Treatment (PubMed)

Reversal of Severe Visual Loss from Syphilitic Chorioretinitis Following Penicillin Treatment A 51-year-old Caucasian male was referred to neuro-ophthalmology clinic for an evaluation of acute onset of painless visual loss in the left eye. The ocular examination revealed subtle retinal changes suspicious for chorioretinitis. Laboratory workup revealed a reactive Treponema pallidum particle agglutination assay (TP-PA), confirming the diagnosis of ocular syphilis. The patient was treated (...) with intravenous infusion of penicillin with complete recovery of vision and resolution of retinal abnormalities.

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2015 Neuro-Ophthalmology

136. RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery

RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02128113 Recruitment Status : Completed First Posted : May 1, 2014

2014 Clinical Trials

137. Light to Maximize Vision, Minimize Insomnia

acuity Greater than 20° visual field with no lower visual field loss Stable health Male or female Normal color vision Normal hearing Exclusion Criteria: Extreme chronotype Sleep disorders Dementia Smoker Depression Alcohol abuse Use of illegal drugs Use of sleep/wake altering drugs on an acute or as needed basis (including nutraceuticals, antihistamines) Use of light sensitizing drugs Self-reported history of nocturia (>3 times per night) Contacts and Locations Go to Information from the National (...) Light to Maximize Vision, Minimize Insomnia Light to Maximize Vision, Minimize Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Light to Maximize Vision, Minimize Insomnia The safety and scientific

2012 Clinical Trials

138. Acute childhood limp

and potentially life-threatening conditions, such as septic arthritis and malignancy. The underlying cause varies between age-groups because children become susceptible to specific conditions as they progress through childhood. Assessment of a child presenting with acute limp involves: Excluding red flags which may indicate an underlying serious disease or condition, such as nocturnal pain; redness, swelling, or stiffness of the joint or limb; weight loss or anorexia; and fever or night sweats. Identifying (...) that persists for longer than 6 weeks and has no known cause. Systemic symptoms of lethargy and anorexia may be present. Often children with JIA are otherwise well and blood tests and X-rays may be normal. Be aware that there is a high risk of uveitis in children with JIA and this may be asymptomatic initially. If undiagnosed and untreated, uveitis can lead to loss of vision. [ ] Sever's disease Sever's disease Sever's disease or apophysitis of the calcaneus produces heel pain as a result of inflammation

2015 NICE Clinical Knowledge Summaries

139. Sudden Visual Loss (Treatment)

with placebo at 6 months. [ ] There was, however, indication that treating with steroids hastened the rate of return of vision to normal compared with placebo. When choosing this treatment, oral steroids must be preceded by intravenous steroids, as oral steroids alone resulted in fewer patients achieving normal visual acuity compared with controls and may in fact be associated with increased recurrence rates. In cases of acute CRAO, conservative therapy may include the following: [ ] Ocular massage Topical (...) . [ ] Surgical patients experienced both intraoperative and postoperative adverse events, including CRAO during surgery and light perception vision at 6 months. There was also immediate loss of light perception following surgery and loss of vision that persisted to the 12-month visit. Central Retinal Vein Occlusion Surgical options for CRVO include radial optic neurotomy, chorioretinal venous anastomosis, vitrectomy, and retinal vein injection with tPA. None of these surgical treatments has been proven

2014 eMedicine.com

140. Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure

or better [ Time Frame: 6 Months ] Secondary Outcome Measures : The percentage of treated eyes within +/- 1.00D of target refraction [ Time Frame: 6 Months ] The percentage of treated eyes within +/- 0.50D of target refraction [ Time Frame: 6 Months ] The percentage of treated eyes with a monocular uncorrected high contrast distance VA of 20/40 or better [ Time Frame: 6 Months ] Preservation of VA: Loss of more than 2 lines in monocular BCVA for distance vision [ Time Frame: 6 Months ] The percentage (...) Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2011 Clinical Trials

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