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Acute Vision Loss

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81. Trends in US Emergency Department Visits for Pediatric Acute Ocular Injury. (PubMed)

Trends in US Emergency Department Visits for Pediatric Acute Ocular Injury. There is a lack of literature describing the incidence of pediatric acute ocular injury and associated likelihood of vision loss in the United States. Understanding national pediatric eye injury trends may inform future efforts to prevent ocular trauma.To characterize pediatric acute ocular injury in the United States using data from a stratified, national sample of emergency department (ED) visits.A retrospective (...) with acute traumatic ocular injuries were collected and temporal trends in the incidence of ocular injuries by age, risk of vision loss, and mechanism of injury were explored.In 2014, there were an estimated 163 431 (95% CI, 151 235-175 627) ED visits for pediatric acute ocular injury. Injured children were more often male (63.0%; 95% CI, 62.5-63.5) and in the youngest age category (birth to 4 years, 35.3%; 95% CI, 34.4-36.2; vs 10-14 years, 20.6%; 95% CI, 20.1-21.1). Injuries commonly resulted from

2018 JAMA ophthalmology

82. Comparing treatment of acute retinal necrosis with either oral valaciclovir or intravenous aciclovir. (PubMed)

criteria included insufficient patient records or follow-up (<150 days). Fifty-six patients had unilateral ARN, while 6 had bilateral ARN. Patients who received intravenous acyclovir on diagnosis (n = 33) were compared with patients treated with oral valacyclovir (n = 29) across outcomes including best-corrected visual acuity, retinal detachment, severe vision loss, and other complications. The impact of adjunctive intravitreal antiviral and prophylactic barrier laser treatment was also assessed.Change (...) in best-corrected visual acuity was not significantly different for eyes treated initially with intravenous therapy vs oral therapy over 5 years of follow-up data (P = .16). There was no difference in the rates of severe vision loss between the 2 groups (46% and 59%, respectively, P = .18), or of those eyes retaining good vision (28% vs 31%, respectively, P = .80). Retinal detachment occurred in 63% of cases and did not differ across treatment groups (62% vs 66%, respectively, P = .67). Barrier laser

2018 American Journal of Ophthalmology

83. Left acute neovascular glaucoma after right carotid endarterectomy (PubMed)

Left acute neovascular glaucoma after right carotid endarterectomy Carotid endarterectomy is a commonly performed vascular surgical procedure with well-known complications, such as stroke and nerve injury. Neovascular glaucoma (NVG) is an exceedingly rare complication after carotid endarterectomy that can result in loss of vision. All previous reports of NVG after carotid endarterectomy have occurred on the same side as the carotid surgery; in this report, we present a case of left-sided NVG

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2018 Journal of Vascular Surgery Cases and Innovative Techniques

84. Acute retinal arterial ischemia (PubMed)

Acute retinal arterial ischemia Acute retinal arterial ischemia, which includes transient monocular vision loss (TMVL), branch retinal artery occlusion (BRAO), central retinal artery occlusion (CRAO) and ophthalmic artery occlusion (OAO), is most commonly the consequence of an embolic phenomenon from the ipsilateral carotid artery, heart or aortic arch, leading to partial or complete occlusion of the central retinal artery (CRA) or its branches. Acute retinal arterial ischemia is the ocular (...) equivalent of acute cerebral ischemia and is an ophthalmic and medical emergency. Patients with acute retinal arterial ischemia are at a high risk of having further vascular events, such as subsequent strokes and myocardial infarctions (MIs). Therefore, prompt diagnosis and urgent referral to appropriate specialists and centers is necessary for further work-up (such as brain magnetic resonance imaging with diffusion weighted imaging, vascular imaging, and cardiac monitoring and imaging) and potential

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2018 Annals of eye science

85. Protective effects of Rutin against methanol induced acute toxic optic neuropathy: an experimental study (PubMed)

and decreasing the oxidative stress. New treatment options are warranted in this disease to avoid loss of vision in patients. (...) Protective effects of Rutin against methanol induced acute toxic optic neuropathy: an experimental study To determine the effects of Rutin on methanol induced optic neuropathy and compare the results with the effects of ethanol.Totally 30 rats were divided into 5 groups, with 6 rats in each group as follows: healthy controls (C), methotrexate (MTX), methotrexate+methanol (MTM), methotrexate+methanol+ethanol (MTME) and methotrexate+ methanol+Rutin (MTMR). In all rabbits except those

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2018 International journal of ophthalmology

86. Acute blindness as a presenting sign of childhood endemic Burkitt’s lymphoma in Cameroon: a case report (PubMed)

as a presentation sign is rare.A 13 year old African female presented to our facility with a 3 week history of painful abdominal distention, and loss of vision of the left eye. On examination, there was a huge abdominopelvic mass, left breast mass and complete blindness of the left eye associated with mydriatic pupils non-responsive to light. An abdominal ultrasound showed a huge hypoechoic mass arising from the pelvis and protruding into the abdomen. The jaws, teeth and maxilla were all normal. A fine needle (...) Acute blindness as a presenting sign of childhood endemic Burkitt’s lymphoma in Cameroon: a case report Endemic Burkitt's lymphoma is found predominantly in malaria holoendemic zones, typically in the tropical rain forest of Africa. It usually presents as an extra-nodal tumour in children and young adults with predilection for jaws and soft tissues of the abdomen. Clinical features depend on the primary tumour site, extent of the disease and histologic subtype. Acute blindness

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2018 Journal of medical case reports

87. Acute Macular Neuroretinopathy following Oral Intake of Adrenergic Flu Treatments (PubMed)

Acute Macular Neuroretinopathy following Oral Intake of Adrenergic Flu Treatments The purpose of this study was to report a case series of patients with acute macular neureretinopathy in which patients concomitantly used ephedrine or pseudo-ephedrine.This is a retrospective case review.Two patients with retinal findings consistent with acute macular neuroretinopathy are presented.Acute macular neuroretinopathy should be considered in any young patient with unexplained loss of vision and exposed

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2018 Case reports in ophthalmology

88. Reduction in interhemispheric functional connectivity in the dorsal visual pathway in unilateral acute open globe injury patients: a resting-state fMRI study (PubMed)

calcarine/lingual/cuneus (BA18, 19, 30) and middle occipital gyrus (BA18, 19). The OGI patients had abnormal interhemispheric FC in the dorsal visual pathway, which may represent the pathophysiological mechanism that underlies acute vision loss after OGI. (...) Reduction in interhemispheric functional connectivity in the dorsal visual pathway in unilateral acute open globe injury patients: a resting-state fMRI study This study investigated the changes in interhemispheric functional connectivity (FC) of the whole brain in open globe injury (OGI) patients, using voxel-mirrored homotopic connectivity (VMHC), and their relationships with clinical features. Totally, 16 male and 2 female acute OGI patients and 18 sex, age, and education-matched healthy

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2018 International journal of ophthalmology

89. VERNONIA AMYGDALINA DELILE EXHIBITS A POTENTIAL FOR THE TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA (PubMed)

of the 20th century alone. Therefore, the aim of the present study was to explore the efficacy of a medicinal plant, Vernonia amygdalina Delile (VAD), as a new targeted therapy for the management of acute promyelocytic leukemia (APL), using HL-60 cells as a test model. To address our specific aim, HL-60 promyelocytic leukemia cells were treated with VAD. Live and dead cells were determined by acridine orange and propidium iodide (AO/PI) dye using the Cellometer Vision. The extent of DNA damage (...) VERNONIA AMYGDALINA DELILE EXHIBITS A POTENTIAL FOR THE TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA The World Health Organization (WHO) has been on front line to encourage developing countries to identify medicinal plants that are safe and easily available to patients. Traditional medicine represents the first-treatment choice for the healthcare of approximately 80% of people living in developing countries. Also, its use in the United States has increased by 38% during within the last decade

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2018 Global journal of advanced engineering technologies and sciences

90. Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor (PubMed)

Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Gastrointestinal Stromal Tumor and Hurthle Cell Tumor Acute posterior multifocal placoid pigment epitheliopathy (APMPEE) is a chorioretinal inflammatory disease of unknown origin. Patients usually present with a rapid loss of central/paracentral vision over the course of a week in both eyes. The fundus exhibits rapid appearance of multiple deep subretinal yellow-white, flat lesions at the RPE/choriocapillaris level (...) . This in turn causes changes of both the ellipsoid zone and RPE which can result in permanent central vision loss. The pathogenesis is controversial but is associated with a recent viral illness and can involve the central nervous system with concern for cerebral vasculitis. Rare reports of APMPEE associated with systemic vasculitis such as Wegener's granulomatosis and malignancy such as clear cell renal carcinoma have been reported. We report a case of APMPEE with concurrent diagnosis of gastrointestinal

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2018 Case reports in ophthalmological medicine

91. Acute zonal occult outer retinopathy: Is optical coherence tomography angiography useful? (PubMed)

Acute zonal occult outer retinopathy: Is optical coherence tomography angiography useful? A 44-year-old female presented with central vision loss and photopsia in both eyes since 2 months. Multimodal imaging, field defects, electroretinogram abnormalities, and spectral domain optical coherence tomography changes were all suggestive of acute zonal occult outer retinopathy. En-face optical coherence tomography angiography (OCTA) images demonstrated hyper-reflective dots at the level of ellipsoid

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2018 Indian journal of ophthalmology

92. Paracentral acute middle maculopathy and the ischemic cascade associated with retinal vascular occlusion. (PubMed)

final visual acuity was 20/25). This pattern was noted to sequentially progress in 2 cases to a diffuse globular PAMM pattern in the INL, or to a pattern of ischemia involving both the middle and inner retinal layers with commensurate vision loss. Globular patterns of PAMM or ischemia involving both the middle and inner retina correlated with poorer visual outcomes (average final visual acuity was counting fingers at 5.5 ft). These various patterns of ischemia developed in eyes with retinal vascular (...) Paracentral acute middle maculopathy and the ischemic cascade associated with retinal vascular occlusion. To analyze the spectrum of ischemia associated with paracentral acute middle maculopathy (PAMM) in eyes with acute retinal vascular occlusion and to describe an ischemic cascade.A retrospective observational case series.Patients presenting with PAMM secondary to acute retinal vascular occlusion were identified. Analysis of multimodal imaging was performed at baseline and at follow-up visits

2018 American Journal of Ophthalmology

93. More than meets the eye: Point-of-care ultrasound diagnosis of acute optic neuritis in the emergency department. (PubMed)

More than meets the eye: Point-of-care ultrasound diagnosis of acute optic neuritis in the emergency department. Optic neuritis (ON) is an inflammatory condition that causes demyelination and thickening of the optic nerve leading to acute/subacute vision loss. It is frequently associated with other conditions like multiple sclerosis, but is often misdiagnosed, which can lead to a suboptimal prognosis. Ultrasound is rarely utilized to help make this diagnosis, even though it can easily detect

2018 American Journal of Emergency Medicine

94. Requirement for Head Magnetic Resonance Imaging in Children Who Present to the Emergency Department With Acute Nontraumatic Visual Disturbance. (PubMed)

who underwent head MRI as an evaluation for acute nontraumatic visual disturbance as a chief complaint in our pediatric emergency department between March 2010 and March 2015. The symptoms of visual disturbance were blurred vision, diplopia, loss of vision, and visual hallucination. Head MRI findings were considered positive when lesions could explain the symptoms.We identified 39 patients (25 with blurred vision, 9 with diplopia, 3 with loss of vision, and 2 with visual hallucination) with a mean (...) Requirement for Head Magnetic Resonance Imaging in Children Who Present to the Emergency Department With Acute Nontraumatic Visual Disturbance. This study aimed to investigate the clinical features and head magnetic resonance imaging (MRI) findings in children who presented to the emergency department with acute nontraumatic visual disturbance and to study related clinical factors for discovering positive lesions on head MRI.We performed a retrospective study of 1-month to 15-year-old children

2018 Pediatric Emergency Care

95. Management of Acute Retinal Ischemia: Follow the Guidelines! (PubMed)

Management of Acute Retinal Ischemia: Follow the Guidelines! Acute retinal arterial ischemia, including vascular transient monocular vision loss (TMVL) and branch (BRAO) and central retinal arterial occlusions (CRAO), are ocular and systemic emergencies requiring immediate diagnosis and treatment. Guidelines recommend the combination of urgent brain magnetic resonance imaging with diffusion-weighted imaging, vascular imaging, and clinical assessment to identify TMVL, BRAO, and CRAO patients (...) at highest risk for recurrent stroke, facilitating early preventive treatments to reduce the risk of subsequent stroke and cardiovascular events. Because the risk of stroke is maximum within the first few days after the onset of visual loss, prompt diagnosis and triage are mandatory. Eye care professionals must make a rapid and accurate diagnosis and recognize the need for timely expert intervention by immediately referring patients with acute retinal arterial ischemia to specialized stroke centers

2018 Ophthalmology

96. Strokes and vision: The management of ischemic arterial disease affecting the retina and occipital lobe. (PubMed)

Strokes and vision: The management of ischemic arterial disease affecting the retina and occipital lobe. Embolic disease of the anterior or posterior vascular territories may lead to disturbance of vision. Although death from this is uncommon, morbidity remains relatively high: Visual field loss may impair or preclude reading and driving and these are important influences on quality of life. Visual symptoms of stroke mean that patients may present to ophthalmologists with isolated visual (...) symptoms, rather than directly to an emergency department. It is important to diagnose stroke and transient ischemic attacks accurately, as well as to manage them appropriately, as they are important harbingers of further cerebrovascular events. Ophthalmologists are therefore well placed to ensure that these patients receive appropriate acute treatment and secondary prevention. This article reviews the evidence for managing patients presenting with visual symptoms of vascular events. It reviews

2014 Survey of Ophthalmology

97. Xience or Vision Stent Management of Angina in the Elderly

Xience or Vision Stent Management of Angina in the Elderly Xience or Vision Stent Management of Angina in the Elderly - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Xience or Vision Stent Management (...) or Vision Stent, Management of Angina in the Elderly Study Start Date : November 2008 Actual Primary Completion Date : August 2012 Actual Study Completion Date : August 2012 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Drug eluting stent Percutaneous coronary intervention Procedure: Percutaneous Coronary Intervention using drug eluting stents Percutaneous Coronary Intervention using drug eluting stents Other Name

2014 Clinical Trials

98. Miller Fisher syndrome with acute angle-closure glaucoma as the first manifestation: A case report. (PubMed)

Miller Fisher syndrome with acute angle-closure glaucoma as the first manifestation: A case report. There were no reports of Miller Fisher syndrome (MFS) with acute angle-closure glaucoma as the first manifestation.A 78-year-old female patient was admitted to our hospital with pain in her left eye, blurred vision along with nausea, and vomiting for 2 days. It was extremely rare that ophthalmoplegia, loss of tendon reflexes, and ataxia, did not occur in the early stages of MFS, and initial (...) presentation was only dilated pupis and an increase in intraocular pressure.The final diagnosis of the patient was MFS.Intravenous immunoglobulins were administered.Ophthalmoplegia, walking instability, and ataxia gradually improved. At 3 months follow-up, there was no neurological deficit, and the patient could completely self-care.This is the first report of MFS patient with acute angle closure glaucoma as the first manifestation. Consideration should be given to the possibility of incorporating

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2017 Medicine

99. Bilateral acute myopia and angle closure glaucoma induced by Ma-huang (Ephedra): A case report. (PubMed)

Bilateral acute myopia and angle closure glaucoma induced by Ma-huang (Ephedra): A case report. Cases of bilateral acute angle closure have been reported after use of various drugs.A 52-year-old woman visited the emergency room and complained of acute bilateral ocular pain and decreased vision accompanied by headache, nausea, and vomiting. One day before, she had started a herbal medicine containing Ma-huang for weight loss. On examinations, myopic shift, edematous cornea, increased intraocular (...) pressure, shallow anterior chamber, and thickened choroid on both eyes were observed.Angle closure glaucoma induced by drug (Ma-huang).To promptly quit the offending drug and apply ocular hypotensives and cycloplegics.Her symptoms and signs were relieved after antiglaucoma medications and no significant recurrence has been occurred.Physicians prescribing weight loss medications containing Ma-huang must be aware of the potentially sight-threatening adverse effect of bilateral acute angle

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2017 Medicine

100. The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A Review. (PubMed)

permanent central vision loss. While definitive evidence of damage to the retinal nerve fiber layer is lacking, patients receiving repeated injections should be monitored for ocular hypertension and patients in whom sustained ocular hypertension subsequently developed should be periodically monitored for glaucomatous changes with optic nerve optical coherence tomography and static visual fields.Copyright © 2017 Elsevier Inc. All rights reserved. (...) The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A Review. The acute and chronic effects of repeated intravitreal antivascular endothelial growth factor (VEGF) injections on intraocular pressure have not been fully characterized, and the development of sustained ocular hypertension could adversely affect patients who are at risk of glaucomatous optic neuropathy. As expected, volume-driven, acute ocular hypertension

2017 Survey of Ophthalmology

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