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Acute Vision Loss

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181. [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]

<10 mm evident only on gradient-echo MRI) Intrapericardial bleed with cardiac tamponade Hypovolaemic shock or severe hypotension due to bleeding and requiring pressors or surgery Significantly disabling (eg. intraocular with permanent vision loss) Clinically overt or apparent bleeding associated with a decrease in Hb of more than 30 g/L (1.9 mmol/L; 0.465 mmol/L) Transfusion of 2 or more units (whole blood or packed red blood cells [PRBCs]) for bleeding. Number of Participants With Premature (...) [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2013 Clinical Trials

182. MGuardâ„¢ Prime Stent System Clinical Trial in Patients With Acute ST Elevation Myocardial Infarction

MGuardâ„¢ Prime Stent System Clinical Trial in Patients With Acute ST Elevation Myocardial Infarction MGuard™ Prime Stent System Clinical Trial in Patients With Acute ST Elevation Myocardial Infarction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. MGuard™ Prime Stent System Clinical Trial in Patients With Acute ST Elevation Myocardial Infarction (MASTER-II) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01869738 Recruitment Status : Terminated (low enrollment rate) First Posted : June 5, 2013 Last

2013 Clinical Trials

183. A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis

: No Criteria Inclusion criteria Ability to provide written informed consent before any study assessment is performed. Male and female patients aged between 18 and 55 years, inclusive. Diagnosis of clinically unilateral acute demyelinating optic neuritis (ADON) Clinical signs and symptoms of ADON starting within the 14 day prior to intended randomization (loss of vision, pain on movement, impairment of color vision). The qualifying episode of optic neuritis must be the first clinical episode of optic (...) A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis A Trial of Neuroprotection With ACTH in Acute Optic Neuritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Trial of Neuroprotection

2013 Clinical Trials

184. Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury

known as orthostatic hypotension (OH). Due to a decrease in cerebral oxygenation, affected individuals can develop debilitating symptoms including lightheadedness, blurred vision, fatigue and even loss of consciousness. Recent evidence suggests that OH has a negative impact on cognition in individuals with SCI. Clinical observations suggest that OH can lead to neurological deterioration in individuals who may otherwise have a stable SCI. The presence of symptomatic OH prevented participation in 43 (...) Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2013 Clinical Trials

185. Acute visual changes in the elderly. (PubMed)

Acute visual changes in the elderly. Changes in vision are common complaints among the geriatric population. Causes range from cataracts and glaucoma to cerebral strokes or other systemic diseases. Loss of vision may be the turning point from independence to dependence in an elderly person's life. This article focuses on acute vision changes and provides a systematic, symptom-based approach to the evaluation and diagnosis of these processes. It is important that the primary practitioner (...) or geriatrician recognize and evaluate acute vision changes, determine whether a treatable or reversible condition exists, and know when to refer to an ophthalmologist or neurologist for a complete evaluation and management.Copyright © 2013 Elsevier Inc. All rights reserved.

2013 Clinics in Geriatric Medicine

186. Clinical Presentation and Outcome of the Orbital Complications Due to Acute Infective Rhino Sinusitis (PubMed)

Clinical Presentation and Outcome of the Orbital Complications Due to Acute Infective Rhino Sinusitis To describe the clinical presentation and visual outcome of patients with orbital complications of acute infective rhino sinusitis. This is a retrospective case series of patients diagnosed with of orbital involvement due to acute infective rhino sinusitis, who presented to eye OPD between July 2007 and July 2009. The medical records were reviewed with particular emphasis on clinical (...) presentation and management. Twelve patients with an average age of 40.3 years (range, 14-65 years) were studied. The most common presentating symptom was diminution of vision (66.6 %) followed by proptosis, ptosis (33.3 %) and globe displacement (16.6 %). The most common orbital complication noted was orbital cellulitis (83.3 %). Majority of the patients had multiple sinus involvement. Ethmoid sinus was the most common sinus involved (91.6 %). Surgical intervention was required in 75 % of patients. Three

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2013 Indian Journal of Otolaryngology and Head & Neck Surgery

187. Acute visual loss after spinal surgery. (PubMed)

Acute visual loss after spinal surgery. To report visual loss after prone spinal surgery.Computed tomography scan, fundus photography, optical coherence tomography (OCT).A 56-year-old man demonstrated loss of vision in the left eye after cervical spinal surgery. Clinical examination revealed loss of vision to finger counting, severe visual field defect and blurred neural rim area around the optic disc in the left eye. Six weeks later, visual acuity in the left eye was 6/9 and there was inferior (...) visual field defect. Six months after the surgery, significant reduction of retinal nerve fibre layer thickness around the optic nerve head was measured with OCT, consistent with the visual field defect.Ischemic optic neuropathy is the most common cause of visual loss after spine surgery and special emphasis should be given to protect the eye against possible pressure during the surgery.

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2010 Acta ophthalmologica

188. Acute bacterial endophthalmitis after intravitreal bevacizumab injection: Case report and literature review (PubMed)

of 1 mg/0.1 ml vancomycin, 2.25 mg/0.1 ml ceftazidime, 5 mg/0.1 ml fortified amphotericin-B and 4 mg/0.1 ml dexamethasone. Postoperatively the patient improved significantly. However, vision improved from hand motion to counting fingers secondary to severe retinal ischemia. Acute endophthalmitis can develop after intravitreal bevacizumab injections and cause profound visual loss. A review of literature was also performed for similar cases. (...) Acute bacterial endophthalmitis after intravitreal bevacizumab injection: Case report and literature review A case report of a 52 year old male who received intravitreal bevacizumab and developed culture positive endophthalmitis. Vitreous culture indicated that endophthalmitis was caused by Staphylococcus epidermidis. The patient was initially managed with intravitreal injection of ceftazidime and vancomycin, followed by pars plana lensectomy, pars plana vitrectomy with intravitreal injection

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2012 Saudi Journal of Ophthalmology

189. Cystoid Macular Edema in Acute Presentation of Central Retinal Artery Occlusion (PubMed)

Cystoid Macular Edema in Acute Presentation of Central Retinal Artery Occlusion A seventy-six-year-old lady with poor vision of the left eye due to previous retinal detachment presented with acute visual loss of her right eye secondary to central retinal artery occlusion. Clinical examination showed a pale right optic disc, macular edema, and a cherry red spot. Optical coherence tomography done four hours after onset showed right acute cystoid macular edema and diffuse inner retinal thickening (...) . Subsequent treatment with intravenous carbonic anhydrase inhibitor resulted in some visual improvement. Central retinal artery occlusion has been known to produce diffuse intraretinal edema instead of cystoids changes. We would like to discuss a case of acute cystoid macular edema in acute central retinal artery occlusion.

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2012 Case reports in ophthalmological medicine

190. Unilateral acute idiopathic maculopathy. 1991. (PubMed)

Unilateral acute idiopathic maculopathy. 1991. This is a report of nine patients who experienced sudden, severe, unilateral central vision loss following a flulike illness. Each patient had an exudative detachment of the macula. All patients experienced a spontaneous resolution of the acute macular manifestations with near-complete recovery of vision. A characteristic "bull's-eye" appearance in the macula persisted. The acute manifestations of the disorder did not recur in any of the patients (...) during the period of follow-up. The constellation of findings was suggestive of an inflammatory disease of the retinal pigment epithelium, but a specific causative agent could not be identified. The acute clinical and angiographic features, the natural course, and the residual pigment epithelial derangement were not consistent with any previously described disorder.

2012 Retina

191. Acute bilateral blindness as a presenting symptom of Non-Hodgkin's lymphoma. (PubMed)

Acute bilateral blindness as a presenting symptom of Non-Hodgkin's lymphoma. NHL usually presents with lymphadenopathy or symptoms related to compression by the primary tumor of surrounding structures. While the head and neck region is a common site of involvement, blindness is rarely a presenting symptom. We report here the case of a child who presented to the emergency room with acute bilateral loss of vision and no other symptoms. Cranial imaging studies revealed a solid mass of the skull (...) base with compression on optic nerves. Diagnosis of Burkitt's lymphoma was confirmed after biopsy. The patient had partial vision improvement two days after optic nerve decompression which was done immediately at the night of presentation.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

2012 International Journal of Pediatric Otorhinolaryngology

192. 215ON201 BIIB033 In Acute Optic Neuritis (AON)

their last dose of study treatment. Key Exclusion Criteria: Prior episode(s) of optic neuritis or loss of vision not due to AON. Subjects with an established diagnosis of multiple sclerosis are excluded except if newly diagnosed based on the current episode of AON and positive brain magnetic resonance imaging results consistent with the 2010 revisions to the McDonald's criteria. Previous history of a clinically significant disease. Females who have a positive pregnancy test result, or who are pregnant (...) 215ON201 BIIB033 In Acute Optic Neuritis (AON) BIIB033 In Acute Optic Neuritis (AON) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. BIIB033 In Acute Optic Neuritis (AON) The safety and scientific validity

2012 Clinical Trials

193. The MENDSII Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure

or lack of commitment to aggressive treatment by family/medical team (e.g., likely to withdraw life support measures within 24 hrs of screening) Inability to understand English or deafness or vision loss that will preclude delirium evaluation. The inability to understand English (for example in Spanish-only or Mandarin-only speaking patients) will not result in exclusion at centers where the research staff is proficient and/or translation services are actively available in that particular language (...) The MENDSII Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record

2012 Clinical Trials

194. Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON)

more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 50 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Clinical signs and symptoms of ADON in one eye (loss of vision, pain on movement, impairment of color vision) First episode of ADON Able to undergo treatment with IV steroids (...) Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON) Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Fingolimod (FTY720) in Acute

2012 Clinical Trials

195. Sphenoidal mucocele presenting as acute cranial nerve palsies (PubMed)

Sphenoidal mucocele presenting as acute cranial nerve palsies Sphenoidal sinus mucoceles are indolent lesions that, when sufficiently large, can compress on the optic canal or superior orbital fissure, rapidly causing loss of vision, optic neuropathy, ptosis, pain, ophthalmoplegia, and diplopia. We herein report a 72-year-old gentleman who presented acutely with Cranial Nerve II, III, and IV palsies secondary to a sphenoidal sinus mucocele that was confirmed on magnetic resonance imaging

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2012 Saudi Journal of Ophthalmology

196. Acute Red Eye

inflammation V. Indications: Ophthalmology Consultation Symptoms suggesting need for emergent or urgent ophthalmology evaluation Moderate to severe and Irregular pupil l involvement Blurred vision with photophobia Acute Conditions prompting emergent or urgent ophthalmology evaluation (HSV) ( ) Acute angle Other conditions where routine ophthalmology evaluation should be considered VI. Evaluation Evaluate Normal Vision Decreased Vision Acute Loss of Vision disease Determine involved Focal hyperemia suggests (...) , Eye Redness , Bloodshot Eye II. History Timing Acute, subacute or chronic Associated symptoms or Blurred Vision Photophobia Associated Conditions Systemic symptoms ( s or ) Recent illness or infection III. Exam: Eye (always) Consider first if light sensitive Delay only in cases of (irrigation precedes acuity exam) Visual fields by confrontation Defect suggests l, or CNS injury Free and painful movement in all directions exam Evaluate for pupil size and reactivity l Exam (typically with ) stain

2015 FP Notebook

197. Outer Retinal Structure in Patients With Acute Zonal Occult Outer Retinopathy. (PubMed)

Outer Retinal Structure in Patients With Acute Zonal Occult Outer Retinopathy. To correlate visual function with high-resolution images of retinal structure using adaptive optics scanning laser ophthalmoscopy (AOSLO) in 4 patients with acute zonal occult outer retinopathy (AZOOR).Observational case series.Four women, aged 18 to 51, with acute focal loss of visual field or visual acuity, photopsia, and minimal funduscopic changes were studied with best-corrected visual acuity (BCVA), Goldmann (...) kinetic and automated perimetry and fundus-guided microperimetry, full-field and multifocal electroretinography (ffERG and mfERG), spectral-domain optical coherence tomography (SD-OCT), and AOSLO imaging. Cone spacing was measured in 4 eyes and compared with 27 age-similar normal eyes. Additional functional testing in 1 patient suggested that cones were absent but rods remained. Serum from all patients was analyzed for anti-retinal antibody activity.In all patients vision loss was initially

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2011 American Journal of Ophthalmology

198. Acute Sphenoid Sinusitis Induced Blindness: A Case Report. (PubMed)

Acute Sphenoid Sinusitis Induced Blindness: A Case Report. Acute, isolated sphenoid sinusitis is a rare but potentially devastating clinical entity. Missing this diagnosis can lead to permanent vision loss due to injury of the optic nerve. Patients may present with preseptal inflammation, lid edema, chemosis, or ophthalmoplegia.We report a case of acute sphenoid sinusitis in a 10-year-old child who presented to the Emergency Department with essentially painless vision loss.Previously healthy (...) returned.Sphenoid sinusitis should be considered in patients presenting with acute vision loss. Awareness, early diagnosis, and intervention help prevent permanent complications.Copyright © 2012 Elsevier Inc. All rights reserved.

2011 Journal of Emergency Medicine

199. RELATIONSHIP BETWEEN BASELINE CLINICAL DATA AND MICROBIOLOGIC SPECTRUM IN ONE HUNDRED PATIENTS WITH ACUTE POSTCATARACT ENDOPHTHALMITIS. (PubMed)

at baseline was studied using univariate and multivariate analyses.One hundred patients were admitted to the hospital with a median delay of 6 days after cataract surgery. The main symptoms were loss of vision (94.9%) and pain (75.5%). Major clinical signs were hypopyon (72%), pupillary fibrin membrane (77.5%), and loss of fundus visibility (90%). Baseline factors significantly associated with microbiologic identification were as follows: diabetes mellitus, a shorter delay of onset, initial visual acuity (...) RELATIONSHIP BETWEEN BASELINE CLINICAL DATA AND MICROBIOLOGIC SPECTRUM IN ONE HUNDRED PATIENTS WITH ACUTE POSTCATARACT ENDOPHTHALMITIS. To correlate the initial ocular presentation with bacterial identification in 100 patients with acute postcataract endophthalmitis.This was a prospective multicenter study. Demographic data, medical history, and the initial eye examination data were recorded on a standardized form. The relationship between bacterial identification and clinical factors

2011 Retina

200. Computed Tomographic Angiogram of an Anterior Communicating Artery Aneurysm Causing Acute Retrobulbar Optic Neuropathy: A Case Report (PubMed)

that caused subarachnoid hemorrhage and vision loss in a 39-year old man. The 3D-CT angiograms were consistent with findings identified directly during surgery. (...) Computed Tomographic Angiogram of an Anterior Communicating Artery Aneurysm Causing Acute Retrobulbar Optic Neuropathy: A Case Report Three-dimensional computed tomographic (3D-CT) angiography is a widespread imaging modality for intracranial vascular lesions. However, 3D-CT angiograms of an anterior communicating artery aneurysm associated with acute retrobulbar optic neuropathy have not been previously described. We present 3D-CT angiograms of an aneurysm of the anterior communicating artery

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2011 Korean journal of ophthalmology : KJO

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