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1,032 results for

Acute Otitis Media Observation

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1021. Causes for massive bacterial colonization on mucosal membranes during infectious mononucleosis: implications for acute otitis media. (Abstract)

Causes for massive bacterial colonization on mucosal membranes during infectious mononucleosis: implications for acute otitis media. A common complication of virus-induced upper respiratory tract infections is acute otitis media caused by bacterial pathogens. Simultaneously, increased bacterial colonization in the nasopharynx occurs. Our intention in this study was to identify the causes of this increased colonization of bacteria by evaluating their coating with the antibacterial substances (...) with bacterial penetration into epithelial cells, may exacerbate the bacterial colonization on oropharyngeal mucosal membranes observed during IM.

2002 International Journal of Pediatric Otorhinolaryngology

1022. Changes in treatment strategies for acute otitis media after full implementation of the pneumococcal seven valent conjugate vaccine. (Abstract)

Changes in treatment strategies for acute otitis media after full implementation of the pneumococcal seven valent conjugate vaccine. Administration of the pneumococcal seven valent conjugate vaccine (PCV-7) results in significant reductions in the incidence of invasive pneumococcal disease and nasopharyngeal colonization rates; however, the reduction in the overall incidence of acute otitis media (AOM) is minimal. Despite an ongoing shortage of PCV-7 in the United States, during which children (...) on serotype-specific AOM reduction rates observed in clinical studies. Clinical success rates of various antimicrobials used in the treatment of AOM in children fully immunized with PCV-7 also are calculated based on projected PCV-7-induced changes in pathogen profiles and documented antimicrobial resistance rates. Questions regarding potential serotype substitution in children with AOM but not invasive pneumococcal disease, the increased incidence of infection with Haemophilus influenzae in children

2003 Pediatric Infectious Dsease Journal

1023. Acute otitis media and facial nerve paralysis in adults. (Abstract)

for facial nerve paralysis secondary to acute otitis media. There were six women and five men without a history of chronic middle ear disease, who ranged in age from 21 to 71 years. Facial palsy was graded with the House-Brackmann scale: four patients had Grade III palsy, six had Grade IV palsy, and one patient had Grade V palsy. Bacteriologic examination of middle ear fluid was performed in four patients Streptococcus pneumoniae was observed in one patient, and the remaining three cultures were (...) Acute otitis media and facial nerve paralysis in adults. The pathophysiology and treatment of facial nerve paralysis associated with acute otitis media are still under debate. The objective of this study was to review treatment strategies and extent of recovery in adult patients with the aim of defining a standard treatment protocol for this rare pathologic condition.Retrospective chart review.University hospital, tertiary referral center.Between 1993 and 2000, 11 patients were admitted

2003 Otology and Neurotology

1024. Randomized, investigator-blinded, multicenter, comparative study of gatifloxacin versus amoxicillin/clavulanate in recurrent otitis media and acute otitis media treatment failure in children. (Abstract)

microbiologic data. The primary outcome measure was clinical resolution of infection at the test-of-cure visit 3-10 days after completing treatment.Clinical resolution of acute otitis media was observed in 79.0% (49 of 62) of clinically evaluable children younger than 2 years and 90.3% (56 of 62) of those 2 years or older who were treated with gatifloxacin as compared with 77.6% (45 of 58) of children younger than 2 years and 79.7% (47 of 59) of children 2 years or older treated with amoxicillin/clavulanate (...) Randomized, investigator-blinded, multicenter, comparative study of gatifloxacin versus amoxicillin/clavulanate in recurrent otitis media and acute otitis media treatment failure in children. Recurrent otitis media and acute otitis media treatment failure are commonly encountered in the pediatric population.To compare the clinical efficacy of gatifloxacin with amoxicillin/clavulanate for the treatment of acute otitis media treatment failure and recurrent otitis media.Three hundred fifty-four

2005 The Pediatric infectious disease journal Controlled trial quality: uncertain

1025. Comparison of two approaches to observation therapy for acute otitis media in the emergency department. (Abstract)

Comparison of two approaches to observation therapy for acute otitis media in the emergency department. This study compared parental adherence to delayed antibiotic therapy for acute otitis media with and without a written prescription in a pediatric emergency department.Children aged 2 to 12 years who met criteria for delayed antibiotic treatment were randomly assigned to observation therapy with or without a prescription. Patients randomly assigned to observation therapy without prescription (...) , respectively. No complications were reported.Observation therapy with and without a prescription were both well accepted by parents of children diagnosed with acute otitis media in an urban pediatric emergency department. Adherence to delayed antibiotic therapy was better for those not offered a prescription. These data suggest that, in the pediatric emergency department setting, observation therapy reduces antibiotic use without compromising satisfaction with the visit.

2008 Pediatrics Controlled trial quality: uncertain

1026. Delayed prescription may reduce the use of antibiotics for acute otitis media: a prospective observational study in primary care. Full Text available with Trip Pro

Delayed prescription may reduce the use of antibiotics for acute otitis media: a prospective observational study in primary care. To evaluate the applicability and the effectiveness of practice guidelines based on a wait-and-see strategy for children with acute otitis media (AOM).Children from 1 to 14 years old having AOM who were referred to primary care pediatric practices.Prospective observational study.Proportion of children having a diagnosis of AOM and eligible for symptomatic treatment (...) for symptomatic treatment only, 743 (67.6%) recovered without antibiotic treatment at 3 days and 716 (65.1%) at 30 days. No complications were observed. Coexistence of a high fever (temperature > or = 38.4 degrees C) and red and bulging tympanic membrane as well as male sex were significantly associated with antibiotic use.Practice guidelines based on a wait-and-see strategy for children with AOM are applicable and effective in primary care. This strategy was able to avoid the administration of antibiotic

2005 Archives of Pediatrics & Adolescent Medicine

1027. Observations on the relation of environmental and behavioral factors to the occurrence of otitis media among Indian children. Full Text available with Trip Pro

Observations on the relation of environmental and behavioral factors to the occurrence of otitis media among Indian children. Studies were conducted to assess the relation of environmental and behaviora factors to occurrence of acute suppurative otitis media (ASOM) among four populations of Indian children in Arizona. Episodes of ASOM were recorded for 1,428 children observed during the first year of life. Data obtained on the households and premises of these children included number of persons (...) . Results did not indicate that any environmental or behavioral factor observed was consistently or strongly associated with either the incidence of ASOM or the frequency of attacks. Similarly, no differences were apparent in the frequency of adverse environmental conditions in homes of infants with contrasting rates of ASOM. Rates of ASOM during the first year of life were not associated with either the presence or the absence of adverse environmental conditions.

1981 Public Health Reports

1028. Treatment of otitis media with observation and a safety-net antibiotic prescription. (Abstract)

Treatment of otitis media with observation and a safety-net antibiotic prescription. Several studies have demonstrated that acute otitis media (AOM) in children can be managed without antibiotics. Because children with AOM have traditionally been treated with antibiotics in the United States, there are concerns that parents may not be comfortable with their children being treated with pain control alone. Recently, Cates in England showed that antibiotic usage for AOM could be decreased (...) by prescribing a safety-net antibiotic prescription (SNAP) to be filled if symptoms do not resolve with observation after 48 hours. It is not clear whether a SNAP will be acceptable to parents in other settings such as the United States. The objective of our study was to determine whether parents in the United States find a SNAP for AOM acceptable and whether antibiotic usage could be decreased by its use.A pediatric practice-based research network in a midwestern community of 1.8 million was the setting

2003 Pediatrics

1029. Diagnostic accuracy and the observation option in acute otitis media: the Capital Region Otitis Project. (Abstract)

Diagnostic accuracy and the observation option in acute otitis media: the Capital Region Otitis Project. Studies of acute otitis media indicate that deferring antibiotics in selected patients is a valid option. This study sought to determine the effects of a multifaceted educational intervention on disease management and treatment attitudes in practitioners caring for acute otitis media (AOM).An expert committee composed of clinical and public health practitioners was convened which reviewed (...) current evidence-based literature on diagnosis and treatment of AOM. A survey instrument to measure attitudes was fashioned and administered to 150 invited practitioners before and after a daylong educational intervention. The intervention was composed of two diagnostic otoscopy workshops; a lecture on an antibiotic-centered approach to treatment, followed by a lecture on the Dutch "observation without antibiotic option" (OWAO), which in 1998 involved withholding antibiotic prescription for selected

2004 International Journal of Pediatric Otorhinolaryngology

1030. Topical ofloxacin for chronic suppurative otitis media and acute exacerbation of chronic otitis media: optimum duration of treatment. (Abstract)

Topical ofloxacin for chronic suppurative otitis media and acute exacerbation of chronic otitis media: optimum duration of treatment. To assess the optimum duration of topical ofloxacin therapy for chronic otitis media and to compare the response between patients with chronic suppurative otitis media (CSOM) and acute exacerbation of chronic otitis media (AE).Prospective observational study.Five university hospitals and 30 affiliated institutions.A total of 294 patients who presented (...) patients than in CSOM patients. The standard topical ofloxacin regimen for chronic otitis media should consist of a 2-week course from the aspect of bacteriologic efficacy, although patients showing insufficient symptomatic improvement after 2 weeks may benefit from another 1 or 2 weeks of therapy. Administration of this drug for as long as 4 weeks can increase the clinical efficacy without causing safety problems.

2003 Otology and Neurotology

1031. A randomized, observer-blind trial of amoxycillin/clavulanate versus cefaclor in the treatment of children with acute otitis media. Augmentin 415 Study Group. (Abstract)

A randomized, observer-blind trial of amoxycillin/clavulanate versus cefaclor in the treatment of children with acute otitis media. Augmentin 415 Study Group. In this randomized, multicenter, observer-blind study, the efficacy, safety and tolerability of amoxycillin/clavulanate and cefaclor were compared in children with a clinical diagnosis of acute otitis media. Patients aged between 1 and 12 years received either amoxycillin/clavulanate (250 mg/62 mg t.i.d., or 125 mg/31 mg t.i.d. if aged (...) was significantly more effective clinically than cefaclor in the treatment of acute otitis media in children.

1998 Journal of chemotherapy (Florence, Italy) Controlled trial quality: uncertain

1032. [Double-blind comparative trial of cefroxadine and cephalexin in the treatment of acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media]. (Abstract)

group (chi 2-test, P less than 0.05). In the assessment of clinical usefulness as well, no significant difference was observed between the 2 groups. In the assessment of overall effects based on the patients whose isolated organisms were sensitive to the drugs, CEX group had more patients not responding to the treatment of acute exacerbation of chronic suppurative otitis media (chi 2-test, P less than 0.05). Bacteriological effects were not significantly different between the 2 drugs in both acute (...) [Double-blind comparative trial of cefroxadine and cephalexin in the treatment of acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media]. A double-blind controlled trial of cefroxadine (CXD) 250 mg t.i.d. was undertaken to objectively evaluate its safety and effectiveness in the treatment of acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media, using cephalexin (CEX) 250 mg q.i.d. as a control drug, and the following

1983 The Japanese journal of antibiotics

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