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Acute Otitis Media Observation

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81. Effects of recurrent acute otitis media on cortical speech-sound processing in 2-year old children. Full Text available with Trip Pro

Effects of recurrent acute otitis media on cortical speech-sound processing in 2-year old children. To investigate at the age of 2 years the effects of childhood recurrent acute otitis media (RAOM) on central auditory processing by using cortical event-related potentials elicited by syllable stimuli.During a 1-year period, 22- to 26-month-old children fulfilling the criteria for tympanostomy tube insertion in Oulu University Hospital, Oulu, Finland, were recruited to the RAOM group (N = 20 (...) was shorter and the frequency MMN amplitude lateralized to the left hemisphere in the RAOM group instead of an adult-like right-hemispheric lateralization observed in the controls. The children with RAOM had a more anterior MMN amplitude scalp distribution for the intensity change than control children. In addition, the MMN amplitude elicited by consonant change was evenly distributed unlike in controls, who had a left-side preponderant lateralization. Taken together, these results suggest an elevated

2014 Ear and hearing

82. Evaluation of the Efficacy of Curcumin in Experimentally Induced Acute Otitis Media in Rats. (Abstract)

Evaluation of the Efficacy of Curcumin in Experimentally Induced Acute Otitis Media in Rats. We investigated the effect of curcumin (CMN) in the treatment of experimentally induced acute otitis media (AOM) in rats.Thirty-two Sprague-Dawley female rats were used, yielding 64 temporal bones. Group 1 was the control group. For groups 2 to 4, AOM was induced experimentally, and saline, antibiotics (sulbactam-ampicillin), or CMN were administered for 14 days to groups 2, 3, and 4, respectively (...) . During the histological examination, thickening of the tympanic membrane, damage to the epithelium, inflammation, and sclerosis were evaluated.The AOM+antibiotic and AOM+CMN groups exhibited reduced histological damage compared with the AOM+saline group. No significant differences in thickening of the tympanic membrane or damage to the epithelium or inflammation were observed between the AOM+antibiotic and the AOM+CMN groups. However, the sclerosis values of the AOM+CMN group were significantly lower

2014 Rhinology and Laryngology

83. Craniofacial shape in children with and without a positive otitis media history. Full Text available with Trip Pro

Craniofacial shape in children with and without a positive otitis media history. Past studies using traditional morphometric approaches have reported a handful of differences in craniofacial dimensions between individuals with and without otitis media (OM). In this study, a geometric morphometry (GM) approach was used to determine if craniofacial shape is different among children with no history of OM and a history of recurrent acute OM (RAOM) at two different ages.Nineteen standard landmarks (...) , craniofacial size and shape were significantly different between RAOM and Control groups (p<0.05). Shape differences were evident in the relative positions of the mandible, cranial base, external acoustic meatus, sphenoid and palate. Those shape differences were not found in the 6-year old group.At 4 years of age, the RAOM and Control groups have distinct craniofacial morphologies, but by 6 years of age these differences have largely disappeared. This is consistent with the clinical observation that excess

2016 International Journal of Pediatric Otorhinolaryngology

84. A case series of complicated infective otitis media requiring surgery in adults Full Text available with Trip Pro

was retrieved from the archives of the Department of Otolaryngology, Changi General Hospital, Singapore.A total of 12 patients (10 male, two female) underwent emergency surgery for complications of otitis media. The median age of the patients was 25 years. Otalgia, otorrhoea, headache and fever were the main presenting symptoms. Extracranial complications were observed in 11 patients, and six patients had associated intracranial complications. The primary otologic disease was acute otitis media in six (...) A case series of complicated infective otitis media requiring surgery in adults With the advent of antibiotics, complications of otitis media have become less common. It is crucial for physicians to recognise otitis media and treat its complications early. Herein, we present our institution's experience with patients who required emergency surgical intervention for complications of otitis media.Data on patients who underwent emergency surgery for complications of otitis media from 2004 to 2011

2016 Singapore medical journal

85. Xylitol for Otitis Media

with otitis media with effusion as measured by the resolution of middle ear effusion based on physical examination and tympanometry at 6-, 12-, and 18 and 24-weeks post-treatment. Eligible subjects will be randomly assigned to receive either intranasal xylitol spray or a nasal saline spray placebo and will be observed for 24-weeks following initiation of daily xylitol spray or placebo. The primary efficacy endpoint, the time to middle ear effusion resolution with and without the xylitol nasal spray (...) of episodes of acute otitis media and sinonasal symptoms [ Time Frame: 24 weeks ] Tolerability and side effects of intranasal xylitol administration in children [ Time Frame: 24 weeks ] Will be evaluated descriptively and include all subjects exposed to at least one dose of study drug Tympanostomy tube (TT) placement need [ Time Frame: 24 weeks ] The number of subjects that need TT placement in each arm will be assessed. Eligibility Criteria Go to Information from the National Library of Medicine Choosing

2016 Clinical Trials

86. Middle Ear, Acute Otitis Media, Surgical Treatment

Middle Ear, Acute Otitis Media, Surgical Treatment Acute Otitis Media: Practice Essentials, Background, Anatomy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODU5MzE2LW92ZXJ2aWV3 processing > Acute Otitis Media (...) Updated: Apr 13, 2018 Author: John D Donaldson, MD, FRCSC, FACS; Chief Editor: Arlen D Meyers, MD, MBA Share Email Print Feedback Close Sections Sections Acute Otitis Media Overview Practice Essentials In the United States, acute otitis media (AOM), defined by convention as the first 3 weeks of a process in which the middle ear shows the signs and symptoms of acute inflammation, is the most common affliction necessitating medical therapy for children younger than 5 years. [ , , ] See the image below

2014 eMedicine Surgery

87. Middle Ear, Acute Otitis Media, Medical Treatment

Middle Ear, Acute Otitis Media, Medical Treatment Acute Otitis Media: Practice Essentials, Background, Anatomy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODU5MzE2LW92ZXJ2aWV3 processing > Acute Otitis Media (...) Updated: Apr 13, 2018 Author: John D Donaldson, MD, FRCSC, FACS; Chief Editor: Arlen D Meyers, MD, MBA Share Email Print Feedback Close Sections Sections Acute Otitis Media Overview Practice Essentials In the United States, acute otitis media (AOM), defined by convention as the first 3 weeks of a process in which the middle ear shows the signs and symptoms of acute inflammation, is the most common affliction necessitating medical therapy for children younger than 5 years. [ , , ] See the image below

2014 eMedicine Surgery

88. Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT)

decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 6 Months to 12 Years (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Recurrent acute otitis media (RAOM) or chronic otitis media with effusion (COME (...) medication as directed, complete required study visits, and comply with the protocol. Other protocol-specified inclusion criteria may apply. Exclusion Criteria: Previous otologic or otologic-related surgery within the past 30 days or ongoing complications. Middle ear pathology in either ear other than otitis media. Current acute otitis externa (AOE), malignant otitis externa (MOE) or other conditions which could interfere with evaluation of the study drug. Any systemic disease or disorder, complicating

2015 Clinical Trials

89. Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT)

deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 6 Months to 12 Years (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Recurrent acute otitis media (RAOM) or chronic otitis media with effusion (COME) and eligible for bilateral myringotomy and tympanostomy tube (...) with the protocol. Other protocol-specified inclusion criteria may apply. Exclusion Criteria: Previous otologic or otologic-related surgery within the past 30 days or ongoing complications. Middle ear pathology in either ear other than otitis media. Current acute otitis externa (AOE), malignant otitis externa (MOE) or other conditions which could interfere with evaluation of the study drug. Any systemic disease or disorder, complicating factor or structural abnormality that would negatively affect the conduct

2015 Clinical Trials

90. Pediatric Pharmacokinetic (PK) Study of EXE844 Otic Suspension in Otitis Media at the Time of Tympanostomy Tube Insertion (OMTT)

or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 6 Months to 12 Years (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Recurrent acute otitis media (RAOM) or chronic otitis media with effusion (COME) and eligible for bilateral myringotomy (...) Pediatric Pharmacokinetic (PK) Study of EXE844 Otic Suspension in Otitis Media at the Time of Tympanostomy Tube Insertion (OMTT) Pediatric Pharmacokinetic (PK) Study of EXE844 Otic Suspension in Otitis Media at the Time of Tympanostomy Tube Insertion (OMTT) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have

2015 Clinical Trials

91. Noninvasive depth-resolved optical measurements of the tympanic membrane and middle ear for differentiating otitis media. Full Text available with Trip Pro

Noninvasive depth-resolved optical measurements of the tympanic membrane and middle ear for differentiating otitis media. In this study, optical coherence tomography (OCT) is used to noninvasively and quantitatively determine tympanic membrane (TM) thickness and the presence and thickness of any middle-ear biofilm located behind the TM. These new metrics offer the potential to differentiate normal, acute, and chronic otitis media (OM) infections in pediatric subjects.Case series with comparison (...) group.The TM thickness of 34 pediatric subjects was acquired using a custom-built, handheld OCT system following a traditional otoscopic ear exam.Overall thickness (TM and any associated biofilm) was shown to be statistically different for normal, acute, and chronic infection groups (normal-acute and normal-chronic: P value < 0.001; acute-chronic: P value = 0.0016). Almost all observed scans from the chronic group had an accompanying biofilm structure. When the thickness of the TM and biofilm were

2015 Laryngoscope

92. Does the introduction of acute otitis media clinical practice guidelines impact on the management of this condition? A systematic review

Does the introduction of acute otitis media clinical practice guidelines impact on the management of this condition? A systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6

2016 PROSPERO

93. A systematic review and meta-analysis of antibiotic resistance in paediatric acute otitis media

A systematic review and meta-analysis of antibiotic resistance in paediatric acute otitis media Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address (...) screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used

2016 PROSPERO

94. Incidence of acute otitis media in children: a systematic review

Incidence of acute otitis media in children: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing and effect measures (...) for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full text-screening

2016 PROSPERO

95. Parental information need for acute otitis media in children: a systematic review

Parental information need for acute otitis media in children: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing (...) of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full

2016 PROSPERO

96. Does Tympanometry Predict Antibiotic Usage in Acute Otitis Media?

tympanometry results. If there is a significant disparity between those with a positive tympanogram and those without the investigators may be able to identify a group that will benefit from antibiotics and a group that would not need treatment. Condition or disease Intervention/treatment Acute Otitis Media Procedure: Tympanometry Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 140 participants Observational Model: Cohort Time Perspective: Prospective (...) with receive a tympanogram. There will be no difference between the follow up in the groups based on the tympanometry results. The study is simply observational Type A/C tympanogram Patients with a clinical diagnosis of acute otitis media and a type A or C curve with tympanometry Procedure: Tympanometry All patients enrolled with receive a tympanogram. There will be no difference between the follow up in the groups based on the tympanometry results. The study is simply observational Outcome Measures Go

2013 Clinical Trials

97. The diagnosis and management of acute otitis media. Full Text available with Trip Pro

The diagnosis and management of acute otitis media. This evidence-based clinical practice guideline is a revision of the 2004 acute otitis media (AOM) guideline from the American Academy of Pediatrics (AAP) and American Academy of Family Physicians. It provides recommendations to primary care clinicians for the management of children from 6 months through 12 years of age with uncomplicated AOM. In 2009, the AAP convened a committee composed of primary care physicians and experts in the fields (...) of this practice guideline is the appropriate diagnosis and initial treatment of a child presenting with AOM. The guideline provides a specific, stringent definition of AOM. It addresses pain management, initial observation versus antibiotic treatment, appropriate choices of antibiotic agents, and preventive measures. It also addresses recurrent AOM, which was not included in the 2004 guideline. Decisions were made on the basis of a systematic grading of the quality of evidence and benefit-harm relationships

2013 Pediatrics

98. Dominance of Haemophilus influenzae in ear discharge from Indigenous Australian children with acute otitis media with tympanic membrane perforation. Full Text available with Trip Pro

Dominance of Haemophilus influenzae in ear discharge from Indigenous Australian children with acute otitis media with tympanic membrane perforation. Indigenous Australian children living in remote communities experience high rates of acute otitis media with tympanic membrane perforation (AOMwiP). Otitis media in this population is associated with dense nasopharyngeal colonization of three primary otopathogens; Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis. Little (...) was 0-68% of the total bacterial load (median 2.8%); whereas S. pneumoniae and M. catarrhalis relative abundances were consistently <2% of the total bacterial load. S. pneumoniae and M. catarrhalis abundances were significantly lower in ear discharge compared with nasopharyngeal swabs (p = 0.001, p < 0.001); no significant difference was observed in H. influenzae mean abundance at the two sites.H. influenzae was the dominant otopathogen detected in ear discharge swabs collected from children

2013 BMC Ear, Nose and Throat Disorders

99. Symptoms and otoscopic signs in bilateral and unilateral acute otitis media. Full Text available with Trip Pro

Symptoms and otoscopic signs in bilateral and unilateral acute otitis media. Bilateral acute otitis media (AOM) is considered more severe than unilateral AOM, and several guidelines recommend more active treatment and/or follow-up of bilateral AOM. We studied whether bilateral AOM is a clinically more severe illness than unilateral AOM by comparing symptoms and otoscopic signs between bilateral and unilateral AOM.Two hundred thirty-two children aged 6 to 35 months diagnosed with AOM were (...) differences even when adjusted with age. We observed the following severe otoscopic signs in the bilateral and unilateral AOM group, respectively: moderate/marked bulging of tympanic membrane (63% and 40%; P = .001), purulent effusion (89% and 71%; P = .001), bulla formation (11% and 10%; P = .707), and hemorrhagic redness of tympanic membrane (7% and 10%; P = .386).Bilateral AOM seems to be a clinically only slightly more severe illness than unilateral AOM. Therefore, when assessing AOM severity

2013 Pediatrics

100. Healthcare Seeking Behaviour of Primary Caregivers for Acute Otitis Media (AOM) in Children Aged 6 Months to Less Than 30 Months in Panama

enrolled at former clinical trial sites are different from those enrolled at non clinical trial sites. Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 1330 participants Observational Model: Family-Based Time Perspective: Cross-Sectional Official Title: Healthcare Seeking Behaviour of Primary Caregivers for Acute Otitis Media in Children Aged 6 Months to Less Than 30 Months in Panama Study Start Date : March 2013 Actual Primary Completion Date : May (...) Healthcare Seeking Behaviour of Primary Caregivers for Acute Otitis Media (AOM) in Children Aged 6 Months to Less Than 30 Months in Panama Healthcare Seeking Behaviour of Primary Caregivers for Acute Otitis Media (AOM) in Children Aged 6 Months to Less Than 30 Months in Panama - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study

2013 Clinical Trials

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