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Acute Otitis Media Observation

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21. Trends in Otitis Media Incidence After Conjugate Pneumococcal Vaccination; A National Observational Study. (Abstract)

Trends in Otitis Media Incidence After Conjugate Pneumococcal Vaccination; A National Observational Study. Pneumococcal conjugate vaccine (PCV) was introduced in 2000. The first 7-valent vaccine (PCV7) was followed by a 13-valent vaccine (PCV13) with the same conjugate, and a 10-valent vaccine (PCV10), conjugated to protein D from Haemophilus influenzae. The vaccines offer some protection against pneumococcal acute otitis media (AOM), and, with PCV10, possibly also some protection against H (...) . influenzae AOM. PCV7 was introduced in Sweden in 2009, but from 2010, Swedish counties were free to use either PCV13 or PCV10. The purpose of this study was to investigate the incidence of AOM-related diagnoses and surgical procedures before and after the introduction of PCV in Sweden, but also to compare the areas using PCV13 and PCV10.Data showing the number of AOM diagnoses, ventilation tube insertions, myringotomies, acute mastoiditis cases and mastoidectomies between 2005 and 2014 were extracted

2017 Pediatric Infectious Dsease Journal

22. Otitis Media - Acute Otitis Media & Otitis Media with Effusion

Otitis Media - Acute Otitis Media & Otitis Media with Effusion Otitis Media: Acute Otitis Media (AOM) and Otitis Media with Effusion (OME) - Province of British Columbia theme_3_collection theme_3_frontend theme_3_collection theme_3_frontend Birth, Adoption, Death, Marriage & Divorce theme_1_collection theme_1_frontend theme_1_collection theme_1_frontend British Columbians & Our Governments theme_data_collection data_frontend theme_data_collection data_frontend Data theme_5_collection (...) theme_10_frontend theme_10_collection theme_10_frontend Sports, Recreation, Arts & Culture theme_8_collection theme_8_frontend theme_8_collection theme_8_frontend Taxes & Tax Credits theme_14_collection theme_14_frontend theme_14_collection theme_14_frontend Tourism & Immigration Search default_collection default_frontend Section Navigation Otitis Media: Acute Otitis Media (AOM) and Otitis Media with Effusion (OME) Effective Date: January 1, 2010 Recommendations and Topics Scope This guideline applies

2010 Clinical Practice Guidelines and Protocols in British Columbia

23. Panel 5: Impact of otitis media on quality of life and development. (Abstract)

Panel 5: Impact of otitis media on quality of life and development. To summarize recent advances in knowledge on otitis media (OM) and quality of life (QoL) and development by synthesizing relevant research in this field published between June 1., 2015 until June 1., 2019.Systematic searches of PubMed, Embase and the Cochrane Library using predefined database-specific syntaxes.Articles selected were randomized controlled trials and observational studies with an adequate control group estimating (...) treatment effects of OM including acute OM (AOM), recurrent AOM (RAOM), OM with effusion (OME), chronic OM (COM) and chronic suppurative OM (CSOM). Items included were Health Status, Health Status Indicators, Quality of Life, Functional Status, Specific Learning Disorder, Developmental Disabilities, Language Development Disorders, and Problem Behavior.The electronic database searches yielded a total of 699 records. After screening titles and abstracts, we identified 34 potentially eligible articles

2020 International Journal of Pediatric Otorhinolaryngology

24. Diagnosis and Management of Acute Otitis Media

Diagnosis and Management of Acute Otitis Media The Diagnosis and Management of Acute Otitis Media | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search for this keyword Source User menu Sections Sign up for highlighting editor-chosen studies with the greatest impact on clinical care. The Diagnosis and Management of Acute Otitis (...) Media Allan S. Lieberthal , Aaron E. Carroll , Tasnee Chonmaitree , Theodore G. Ganiats , Alejandro Hoberman , Mary Anne Jackson , Mark D. Joffe , Donald T. Miller , Richard M. Rosenfeld , Xavier D. Sevilla , Richard H. Schwartz , Pauline A. Thomas , David E. Tunkel This article has a correction. Please see: Abstract This evidence-based clinical practice guideline is a revision of the 2004 acute otitis media (AOM) guideline from the American Academy of Pediatrics (AAP) and American Academy of Family

2013 American Academy of Family Physicians

25. The Diagnosis and Management of Acute Otitis Media

The Diagnosis and Management of Acute Otitis Media The Diagnosis and Management of Acute Otitis Media | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search for this keyword Source User menu Sections Sign up for highlighting editor-chosen studies with the greatest impact on clinical care. The Diagnosis and Management of Acute Otitis (...) Media Allan S. Lieberthal , Aaron E. Carroll , Tasnee Chonmaitree , Theodore G. Ganiats , Alejandro Hoberman , Mary Anne Jackson , Mark D. Joffe , Donald T. Miller , Richard M. Rosenfeld , Xavier D. Sevilla , Richard H. Schwartz , Pauline A. Thomas , David E. Tunkel This article has a correction. Please see: Abstract This evidence-based clinical practice guideline is a revision of the 2004 acute otitis media (AOM) guideline from the American Academy of Pediatrics (AAP) and American Academy of Family

2013 American Academy of Pediatrics

26. Ciloxan (Ciprofloxacin) - otitis externa or otitis media

by National Health Insurance and approved for hospital use. Medical, Economic and Public Health Assessment Division 2/16 1 CHARACTERISTICS OF THE MEDICINAL PRODUCT 1.1. Active ingredient Ciprofloxacin 1.2. Indication "Antibiotic treatment for adults and children from 1 year: - for acute otitis externa - for purulent otorrhea of the mastoid cavity and chronic suppurative otitis media with tympanic perforation. Consideration should be given to official guidance on the appropriate use of antibacterial agents (...) ." 1.3. Dosage "Adults and Children 1 year and above Acute otitis externa In adults, the dose is 4 drops of solution in the affected ear 2 times per day. In children, the dose is 3 drops of solution in the affected ear 2 times per day. Treatment duration is 7 days. Purulent otorrhea of the mastoid cavity and chronic suppurative otitis media with tympanic perforation. In adults, the dose is 4 drops of solution in the affected ear 2 times per day. In children, the dose is 3 drops of solution

2014 Haute Autorite de sante

27. Taste Changes in Acute Otitis Media

AOM patients, aged 8-40. Without chronic otitis media, pregnancy or impaired judgement. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 40 participants Observational Model: Case-Only Time Perspective: Prospective Official Title: Taste Changes in Acute Otitis Media Estimated Study Start Date : March 1, 2018 Estimated Primary Completion Date : March 1, 2019 Estimated Study Completion Date : March 1, 2019 Resource links provided by the National (...) Taste Changes in Acute Otitis Media Taste Changes in Acute Otitis Media - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Taste Changes in Acute Otitis Media The safety and scientific validity of this study

2017 Clinical Trials

28. The effect of pneumococcal conjugate vaccines on incidence and microbiology associated with complicated acute otitis media. (Abstract)

The effect of pneumococcal conjugate vaccines on incidence and microbiology associated with complicated acute otitis media. The objectives of this study were to investigate the incidence of complicated acute otitis media (cAOM) as well as the associated microbiology before and after introduction of the 7- and 13-valent pneumococcal conjugate vaccines (PCV-7 and -13), respectively. CAOM comprises "heavy" AOM (AOM demanding hospitalization), mastodismus (M) and acute mastoiditis (AM (...) to 16% in the PCV13-era. GAS decreased from 17% in the pre-vaccine era to 0% in the PCV7-era and 16% in the PCV13-era. The percentage of "no growth" increased from 12% to 38% and 44%, respectively. In the M + AM group, SP decreased to 10% in the PCV13-era compared with 44% in the pre-vaccine era and 41% in the PCV7-era. An increase in GAS from 15% in the pre-vaccine era and PCV7-era to 30% in the PCV13-era was observed. The "no growth" percentage increased from 13% in the pre-vaccine era to 26

2017 International Journal of Pediatric Otorhinolaryngology

29. Antibiotic therapy for children with acute otitis media Full Text available with Trip Pro

acute otitis media by withholding antibiotics and observing the child for clinical improvement. Antibiotics should be promptly provided if the child's infection worsens or fails to improve within 24 to 48 hours. Guidelines and most ongoing studies support these recommendations. Correct choice of regimen, dose, frequency, and length of treatment are all important.Copyright© the College of Family Physicians of Canada. (...) Antibiotic therapy for children with acute otitis media Question Acute otitis media is one of the most common infections in childhood. Routine prescription of antibiotics has led to adverse events and bacterial resistance to antibiotics. I have heard that "watchful waiting" is a good strategy to reduce this potential problem in children older than 6 months of age. Should I apply this strategy in my clinical practice? Answer Watchful waiting can be applied in selected children with nonsevere

2017 Canadian Family Physician

30. Comparison of Efficacy and Safety of Cefpodoxime and Amoxicillin-Clavulanate Potassium in Paediatric Acute Otitis Media in Children below Two Years: A Prospective Longitudinal Study Full Text available with Trip Pro

Comparison of Efficacy and Safety of Cefpodoxime and Amoxicillin-Clavulanate Potassium in Paediatric Acute Otitis Media in Children below Two Years: A Prospective Longitudinal Study Acute Otitis Media (AOM) is one of the frequently diagnosed diseases in children below two years. Amoxicillin-clavulanate potassium is the first line drug in treatment of Paediatric AOM (PAOM). Cefpodoxime has good antimicrobial activity against various types of microorganisms that include causative microorganisms (...) ).The clinical success rates were 93.8% in Group A and 88.2 % in Group B. These rates are comparable and no statistically significant difference was observed between the groups. Few mild and self-limiting AEs were observed and both the drugs were well tolerated.The results of this prospective study showed that a 10-day course of cefpodoxime is therapeutically comparable to amoxicillin-clavulanate potassium in terms of both efficacy and safety for the treatment of PAOM in children below two years.

2017 Journal of clinical and diagnostic research : JCDR

31. The Role of the Notch Signal Pathway in Mucosal Cell Metaplasia in Mouse Acute Otitis Media Full Text available with Trip Pro

The Role of the Notch Signal Pathway in Mucosal Cell Metaplasia in Mouse Acute Otitis Media Otitis media (OM) is a major cause of morbidity in pediatric and adult patients. This inflammatory condition is characterized by mucous cell hyperplasia that is thought to produce mucins from the middle ear mucosa. We are interested in the role of Notch signalling pathway in this inflammatory process. Using an acute otitis media (AOM) mouse model through injection of Streptococcus Pneumoniae (...) into the middle ear, histopathologic examination and quantitative RT-PCR, acute inflammation with the thickness of mucosa, Goblet cell hyperplasia, and cilia loss were determined and gene expression related to the Notch signaling pathway were evaluated. Upregulation of the mucous cell markers, Argr2 and Muc5AC, and downregulation of the cilia cell marker, Foxj1 and Dnai2, were observed in AOM. In addition, genes encoding Notch receptors and ligands (Notch1, Notch2, Notch3, Notch4 and Dll1) and the Notch

2017 Scientific reports

32. Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for preventing recurrent acute otitis media in children: a real-life clinical experience Full Text available with Trip Pro

Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for preventing recurrent acute otitis media in children: a real-life clinical experience Recurrence of acute otitis media (RAOM) is a relevant issue in the clinical practice. "Bacteriotherapy" has been proposed as an option in children with RAOM. Streptococcus salivarius 24SMB nasal spray has been previously demonstrated to reduce the risk of acute otitis media (AOM) in otitis-prone children (...) . The current retrospective and observational study aimed to confirm this outcome in a real-life setting, such as the common pediatric practice. Group A (108 children) served as control; group B (159 children) was treated with S. salivarius 24SMB and Streptococcus oralis 89a nasal spray after the first AOM episode. Active treatment consisted of 3 monthly courses: 2 puffs per nostril twice/day for a week. Group B showed a significant reduction of AOM episodes in comparison with group A (p<0.0001). Notably

2017 International journal of general medicine

33. Healthcare-seeking behaviour of primary caregivers for acute otitis media in children aged 6 months to &lt;30 months in Panama: results of a cross-sectional survey. Full Text available with Trip Pro

Healthcare-seeking behaviour of primary caregivers for acute otitis media in children aged 6 months to <30 months in Panama: results of a cross-sectional survey. Acute otitis media (AOM) is the most common bacterial childhood infection. However, caregivers with children having mild episodes often do not seek healthcare services, which may lead to an under-appreciation of the disease experienced by the community. The objectives of this survey were to estimate the proportion of primary (...) caregivers who went to a healthcare facility when they suspected that their child aged 6 to <30 months was having an AOM episode during the past 6 months and to assess what factors influenced their decision.This observational, cross-sectional survey of primary caregivers (≥18 years), with at least one child aged 6 to <30 months was performed in 19 healthcare facilities in Panama (March to May 2013). A 28-item paper questionnaire was administered to assess demographic data, AOM symptoms, as well

2017 BMC Pediatrics

34. Efficacy of 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine against acute otitis media and nasopharyngeal carriage in Panamanian children - A randomized controlled trial. Full Text available with Trip Pro

Efficacy of 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine against acute otitis media and nasopharyngeal carriage in Panamanian children - A randomized controlled trial. We previously reported 10-valent pneumococcal non-typeable Haemophilus influenzae (NTHi) protein D conjugate vaccine (PHiD-CV) efficacy in a double-blind randomized trial (ClinicalTrials.gov: NCT00466947) against various diseases, including acute otitis media (AOM). Here, we provide (...) % [12.7, 36.7] across all visits. NTHi colonization rates were low and no significant reduction was observed. PHiD-CV showed efficacy against C-AOM and B-AOM in children younger than 24 months, and reduced vaccine-serotype NPC.

2017 Human vaccines & immunotherapeutics Controlled trial quality: predicted high

35. Factors affecting sound energy absorbance in acute otitis media model of chinchilla. Full Text available with Trip Pro

Factors affecting sound energy absorbance in acute otitis media model of chinchilla. Acute otitis media (AOM) is a rapid-onset infection of the middle ear which results in middle ear pressure (MEP), middle ear effusion (MEE), and structural changes in middle ear tissues. Previous studies from our laboratory have identified that MEP, MEE, and middle ear structural changes are three factors affecting tympanic membrane (TM) mobility and hearing levels (Guan et al., 2014, 2013). Sound energy (...) ears and had a smaller effect in 8D ears. MEE reduced the EA at 6-8 kHz in 4D ears and 2-8 kHz in 8D ears and was responsible for the EA peak in both 4D and 8D ears. The residual EA loss due to structural changes was observed over the frequency range in 8D ears and only at high frequencies in 4D ears. The EA measurements were also compared with the published TM mobility loss in chinchilla AOM ears.Copyright © 2017 Elsevier B.V. All rights reserved.

2017 Hearing Research

36. Impact of influenza vaccine on childhood otitis media in Taiwan: A population-based study. Full Text available with Trip Pro

Impact of influenza vaccine on childhood otitis media in Taiwan: A population-based study. Acute otitis media (AOM) is a common infectious disease in children and usually accompanied by a preceding viral respiratory tract infection, especially in the preschool-age population. The study aimed to evaluate impact of influenza vaccine on childhood otitis media.This retrospective cohort study included data for 803,592 children (<10 years old) recorded in Taiwan's National Health Insurance Research (...) episodes/1000 person-seasons [95% CI: 96.4-100.5] to 66.1 episodes/1000 person-seasons [95% CI: 64-68.1]). In addition, with the increased vaccine coverage rate, the outpatient visits for AOM in the influenza season of 2005 and 2006 were significantly lower than that in 2004 (IRR = 0.85 and 0.80, respectively, p < 0.0001).A significant reduction in primary care consultations for children <2 years old was observed after the introduction of the TIV in Taiwan in 2004. With the increased vaccine coverage

2018 PLoS ONE

37. Otitis Media with Effusion (OME)

of a 2004 guideline codeveloped by the American Academy of Otolaryngology—Head and Neck Surgery Foundation, the American Academy of Pediatrics, and the American Academy of Family Physicians, provides evidence-based recommendations to manage otitis media with effusion (OME), defined as the presence of fluid in the middle ear without signs or symptoms of acute ear infection. Changes from the prior guideline include consumer advocates added to the update group, evidence from 4 new clinical practice (...) . Abbreviations and Definitions of Common Terms. Table 1. Abbreviations and Definitions of Common Terms. About 2.2 million diagnosed episodes of OME occur annually in the United States at a cost of $4.0 billion. The indirect costs are likely much higher since OME is largely asymptomatic and many episodes are therefore undetected, including those in children with hearing difficulties or school performance issues. In contrast, acute otitis media (AOM) is the rapid onset of signs and symptoms of inflammation

2016 American Academy of Otolaryngology - Head and Neck Surgery

38. Etiology of Acute Otitis Media in Children Less Than 5 Years of Age: A Pooled Analysis of 10 Similarly Designed Observational Studies. Full Text available with Trip Pro

Etiology of Acute Otitis Media in Children Less Than 5 Years of Age: A Pooled Analysis of 10 Similarly Designed Observational Studies. Acute otitis media (AOM) is an important cause of childhood morbidity and antibiotic prescriptions. However, the relative importance of the well-known otopathogens, Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu), remains unclear because of a limited number of tympanocentesis-based studies that vary significantly in populations sampled, case

2016 Pediatric Infectious Dsease Journal

39. Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish Children

, 2019 Sponsor: GlaxoSmithKline Information provided by (Responsible Party): GlaxoSmithKline Study Details Study Description Go to Brief Summary: The goal of this study is to look at the effect of pneumococcal conjugate vaccines (PCV) on physician-diagnosed otitis media (OM) and acute otitis media (AOM) incidence in Swedish children by collecting and analyzing patient level observational data already available in existing regional and national databases. Condition or disease Intervention/treatment (...) Acute Otitis Media Otitis Media Other: Data collection Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 1 participants Observational Model: Other Time Perspective: Retrospective Official Title: Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish Children Actual Study Start Date : June 16, 2016 Actual Primary Completion Date : May 18, 2017 Actual Study Completion Date : September 14, 2017 Resource links

2016 Clinical Trials

40. Etiology and antimicrobial susceptibility of middle ear fluid pathogens in Costa Rican children with otitis media before and after the introduction of the 7-valent pneumococcal conjugate vaccine in the National Immunization Program: acute otitis media mic Full Text available with Trip Pro

Etiology and antimicrobial susceptibility of middle ear fluid pathogens in Costa Rican children with otitis media before and after the introduction of the 7-valent pneumococcal conjugate vaccine in the National Immunization Program: acute otitis media mic Acute otitis media (AOM) microbiology was evaluated in children after 7-valent pneumococcal conjugate vaccine (PCV7) introduction in Costa Rica (private sector, 2004; National Immunization Program, 2009). This was a combined prospective (...) % vs 25.5%) frequently observed in vaccinated (≥ 2 PCV7 doses or ≥ 1 PCV7 dose at >1 year of age) versus unvaccinated children. S. pneumoniae non-susceptibility rates were 1.1%, 34.5%, 31.7%, and 50.6% for penicillin, erythromycin, azithromycin, and trimethoprim/sulfamethoxazole (TMP-SMX), respectively. H. influenzae non-susceptibility rate was 66.9% for TMP-SMX. Between pre- and post-PCV7 introduction, H. influenzae became more (20.5% vs 25.9%; P-value < 0.001) and S. pneumoniae less (27.7% vs

2015 Medicine

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