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Acute Pancreatitis

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1. Acute pancreatitis

Acute pancreatitis Acute pancreatitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Acute pancreatitis Last reviewed: February 2019 Last updated: January 2019 Summary The most common presenting symptom is mid-epigastric or left upper quadrant pain that radiates to the back. Epigastric tenderness is typical. Associated with nausea and vomiting. A history of cholelithiasis or alcohol intake is often present. Signs (...) of hypovolaemia (including decreased skin turgor, dry mucous membranes, hypotension, and sweating) are common. In more severe cases, the patient may be tachycardic and/or tachypnoeic. Elevated serum lipase or amylase concentration supports, but is not pathognomonic for, the diagnosis of acute pancreatitis. Initial treatment includes resuscitation with intravenous fluids and correction of electrolyte abnormalities, analgesia, and tight glucose control. Treatment of severe acute pancreatitis includes support

2019 BMJ Best Practice

2. Acute pancreatitis

Acute pancreatitis Evidence Maps - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading

2018 Trip Evidence Maps

3. Clinico-radiological comparison and short-term prognosis of single acute pancreatitis and recurrent acute pancreatitis including pancreatic volumetry. Full Text available with Trip Pro

Clinico-radiological comparison and short-term prognosis of single acute pancreatitis and recurrent acute pancreatitis including pancreatic volumetry. The necrosis-fibrosis hypothesis describes a continuum between single attacks of acute pancreatitis (SAP), recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) with endocrine and exocrine pancreatic insufficiency. For prevention purposes we evaluated clinico-radiological parameters and pancreatic volumetry to compare SAP and RAP (...) and provide prognostic relevance on short-term mortality, need for intervention and the hospitalization duration.We retrospectively investigated 225 consecutive patients (150 males, range 19-97years) with acute pancreatitis (74%SAP, 26%RAP) according to the revised Atlanta classification. All patients received an intravenous contrast-enhanced CT after a median time of 5 (IQR 5-7) days after onset of symptoms. Two experienced observers rated the severity of AP by 3 CT scores (CTSI, mCTSI, EPIC). Moreover

2018 PLoS ONE

4. Acute pancreatitis

Acute pancreatitis Acute pancreatitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Acute pancreatitis Last reviewed: February 2019 Last updated: January 2019 Summary The most common presenting symptom is mid-epigastric or left upper quadrant pain that radiates to the back. Epigastric tenderness is typical. Associated with nausea and vomiting. A history of cholelithiasis or alcohol intake is often present. Signs (...) of hypovolaemia (including decreased skin turgor, dry mucous membranes, hypotension, and sweating) are common. In more severe cases, the patient may be tachycardic and/or tachypnoeic. Elevated serum lipase or amylase concentration supports, but is not pathognomonic for, the diagnosis of acute pancreatitis. Initial treatment includes resuscitation with intravenous fluids and correction of electrolyte abnormalities, analgesia, and tight glucose control. Treatment of severe acute pancreatitis includes support

2018 BMJ Best Practice

8. Carbimazole: risk of acute pancreatitis

Carbimazole: risk of acute pancreatitis Carbimazole: risk of acute pancreatitis - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Carbimazole: risk of acute pancreatitis If acute pancreatitis occurs during treatment with carbimazole, immediately and permanently stop treatment. Re-exposure (...) to carbimazole may result in life-threatening acute pancreatitis with a decreased time to onset. Published 18 February 2019 From: Therapeutic area: , Contents Advice for healthcare professionals: cases of acute pancreatitis have been reported very infrequently during treatment with carbimazole if acute pancreatitis occurs, stop carbimazole treatment immediately do not use carbimazole in patients with a history of acute pancreatitis in association with previous treatment re-exposure may result in life

2019 MHRA Drug Safety Update

9. Acute Pancreatitis

Acute Pancreatitis Date of origin: 1998 Last review date: 2013 ACR Appropriateness Criteria ® 1 Acute Pancreatitis American College of Radiology ACR Appropriateness Criteria ® Clinical Condition: Acute Pancreatitis Variant 1: First time presentation, typical abdominal pain, and increased amylase and lipase with high clinical certainty of diagnosis; 48–72 hours after onset of symptoms. Radiologic Procedure Rating Comments RRL* CT abdomen with IV contrast 8 This is the single best, most practical (...) is contraindicated. ??? CT abdomen without and with IV contrast 4 Without contrast portion of examination, this is generally not necessary. ???? Rating Scale: 1,2,3 Usually not appropriate; 4,5,6 May be appropriate; 7,8,9 Usually appropriate *Relative Radiation Level ACR Appropriateness Criteria ® 2 Acute Pancreatitis Clinical Condition: Acute Pancreatitis Variant 3: Continued SIRS, severe clinical scores, leukocytosis, and fever; >7–21 days after onset of symptoms. Radiologic Procedure Rating Comments RRL* CT

2019 American College of Radiology

10. Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis. Full Text available with Trip Pro

Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis. The treatment of people with acute abdominal pain differs if they have acute pancreatitis. It is important to know the diagnostic accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase for the diagnosis of acute pancreatitis, so that an informed decision can be made as to whether the person with abdominal pain has acute pancreatitis. There is currently no Cochrane (...) review of the diagnostic test accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase for the diagnosis of acute pancreatitis.To compare the diagnostic accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase, either alone or in combination, in the diagnosis of acute pancreatitis in people with acute onset of a persistent, severe epigastric pain or diffuse abdominal pain.We searched MEDLINE, Embase, Science Citation Index Expanded, National

2017 Cochrane

11. Pharmacological interventions for acute pancreatitis. Full Text available with Trip Pro

Pharmacological interventions for acute pancreatitis. In people with acute pancreatitis, it is unclear what the role should be for medical treatment as an addition to supportive care such as fluid and electrolyte balance and organ support in people with organ failure.To assess the effects of different pharmacological interventions in people with acute pancreatitis.We searched the Cochrane Central Register of Controlled Trials (CENTRAL, 2016, Issue 9), MEDLINE, Embase, Science Citation Index (...) Expanded, and trial registers to October 2016 to identify randomised controlled trials (RCTs). We also searched the references of included trials to identify further trials.We considered only RCTs performed in people with acute pancreatitis, irrespective of aetiology, severity, presence of infection, language, blinding, or publication status for inclusion in the review.Two review authors independently identified trials and extracted data. We did not perform a network meta-analysis as planned because

2017 Cochrane

12. Endoscopic management of acute necrotizing pancreatitis

Endoscopic management of acute necrotizing pancreatitis Endoscopic management of acute necrotizing pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) evidence-based multidisciplinary guideline – European Society of Gastrointestinal Endoscopy (ESGE) +49-89-9077936-11 Menu https://doi.org/10.1055/a-0588-5365 Published online: 9.4.2018 | Endoscopy 2018; 50: 524–546 © Georg Thieme Verlag KG Stuttgart· New York Explore the ESGE website Menu Contact us +49-89-9077936-0 Follow us ©

2018 European Society of Gastrointestinal Endoscopy

13. Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report From the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee

Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report From the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee Copyright © ESPGHAN and NASPGHAN. All rights reserved. Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report From the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee Maisam Abu-El-Haija, y Soma Kumar, z Jose Antonio Quiros (...) , § Keshawadhana Balakrishnan, jj Bradley Barth, Samuel Bitton, # John F. Eisses, Elsie Jazmin Foglio, yy Victor Fox, zz Denease Francis, §§ Alvin Jay Freeman, jjjj Tanja Gonska, yy Amit S. Grover, # Sohail Z. Husain, Rakesh Kumar, ## Sameer Lapsia, Tom Lin, Quin Y. Liu, yyy Asim Maqbool, zzz Zachary M. Sellers, §§§ Flora Szabo, jjjjjj Aliye Uc, Steven L. Werlin, and ### Veronique D. Morinville ABSTRACT Background: Although the incidence of acute pancreatitis (AP) in children is increasing, management

2018 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

14. Initial Management of Acute Pancreatitis Full Text available with Trip Pro

Initial Management of Acute Pancreatitis American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis - Gastroenterology Email/Username: Password: Remember me Search AGA Journals Search Terms Search within Search Access provided by Volume 154, Issue 4, Pages 1096–1101 American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis x Seth D. Crockett Affiliations Division of Gastroenterology and Hepatology (...) Sachin B. Wani x Sachin B. Wani , x David Weinberg x David Weinberg DOI: | Publication History Published online: February 04, 2018 Expand all Collapse all Article Outline Abbreviations used in this paper: ( ), ( ), ( ), ( ), ( ), ( ), ( ), ( ) This document presents the official recommendations of the American Gastroenterological Association (AGA) on the initial management of acute pancreatitis (AP). The guideline was developed by the AGA’s Clinical Practice Guideline Committee and approved

2018 American Gastroenterological Association Institute

15. Acute Pancreatitis Task Force on Quality: Development of Quality Indicators for Acute Pancreatitis Management. (Abstract)

Acute Pancreatitis Task Force on Quality: Development of Quality Indicators for Acute Pancreatitis Management. Detailed recommendations and guidelines for acute pancreatitis (AP) management currently exist. However, quality indicators (QIs) are required to measure performance in health care. The goal of the Acute Pancreatitis Task Force on Quality was to formally develop QIs for the management of patients with known or suspected AP using a modified version of the RAND/UCLA Appropriateness

2019 American Journal of Gastroenterology

16. Incretin-based glucose-lowering medications and the risk of acute pancreatitis and malignancies: a meta-analysis based on cardiovascular outcomes trials

Incretin-based glucose-lowering medications and the risk of acute pancreatitis and malignancies: a meta-analysis based on cardiovascular outcomes trials Incretin-based Glucose-Lowering Medications and the Risk of Acute Pancreatitis and Malignancies: A Meta-Analysis Based on Cardiovascular Outcomes Trials - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search (...) : Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Diabetes Obes Metab Actions 2019 Nov 21 [Online ahead of print] Incretin-based Glucose-Lowering Medications and the Risk of Acute Pancreatitis and Malignancies: A Meta-Analysis Based on Cardiovascular Outcomes Trials , , , , Affiliations

2020 EvidenceUpdates

17. Rapid Progression of Acute Pancreatitis to Acute Recurrent Pancreatitis in Children. Full Text available with Trip Pro

Rapid Progression of Acute Pancreatitis to Acute Recurrent Pancreatitis in Children. Research is lacking on the natural history of acute pancreatitis (AP) progression to acute recurrent pancreatitis (ARP). The aim of this project was to study the progression from AP to ARP among pediatric patients with pancreatitis to better understand the presentation and natural history of pancreatitis.Patients presenting with AP were included in a prospective database in Research Electronic Data Capture. We (...) with ARP progressed from AP to ARP within 5 months from first diagnosis. A comparison of patients who rapidly progressed to ARP within 3 months (n = 12) to those followed for >3 months without progression in 3 months (n = 97) revealed associations with a higher weight percentile for age (P = 0.045), male sex (P = 0.03), and presence of pancreatic necrosis during first AP attack (P = 0.004). Progression to ARP significantly differed by etiology group with genetics having the highest risk for ARP

2018 Journal of Pediatric Gastroenterology and Nutrition

18. Differences between the outcome of recurrent acute pancreatitis and acute pancreatitis Full Text available with Trip Pro

Differences between the outcome of recurrent acute pancreatitis and acute pancreatitis Overall, a handful of studies are available on the outcomes of recurrent acute pancreatitis (RAP), in comparison to the first episode of acute pancreatitis (AP). We aimed to provide a more complete and updated picture of RAP and how it is different from the initial episode of AP.Consecutive patients admitted with an episode of AP over 8 years were divided into two groups on the basis of prior episodes: AP (...) and RAP. Primary outcome measures were for surgical necrosectomy and mortality.Of the 724 patients (age 39.22 ± 13.25 years, 68% male) with an episode of pancreatitis, 632 (87.3%) had presented with a first episode (AP) and 92 (12.7%) with at least one prior episode (RAP). The incidence of severe pancreatitis was significantly less in RAP patients (10.9%) in comparison to AP patients (48.6%). The requirement of surgical intervention and mortality were less in patients with RAP (1.1 and 2.2

2018 JGH Open: An Open Access Journal of Gastroenterology and Hepatology

19. Classification of Acute Pancreatitis in the Pediatric Population: Clinical Report From the NASPGHAN Pancreas Committee

Classification of Acute Pancreatitis in the Pediatric Population: Clinical Report From the NASPGHAN Pancreas Committee Copyright © ESPGHAL and NASPGHAN. All rights reserved. Classification of Acute Pancreatitis in the Pediatric Population: Clinical Report From the NASPGHAN Pancreas Committee Maisam Abu-El-Haija, y Soma Kumar, z Flora Szabo, § Steven Werlin, jj Darwin Conwell, Peter Banks, and # Veronique D. Morinville, on behalf of the NASPGHAN Pancreas Committee ABSTRACT Introduction: Acute (...) pancreatitis (AP) is an emerging problem in pediatrics, with most cases resolving spontaneously. Approximately 10% to 30%, however, are believed to develop ‘‘severe acute pancreatitis’’ (SAP). Methods: This consensus statement on the classi?cation of AP in pediatrics was developed through a working group that performed an evidence-based search for classi?cation of AP in adult pancreatitis, de?nitions and criteria of systemic in?ammatory response syndrome, and organ failure in pediatrics. Results

2017 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

20. [Effects of early enteral nutrition in patients with mild acute pancreatitis.] Full Text available with Trip Pro

[Effects of early enteral nutrition in patients with mild acute pancreatitis.] Acute pancreatitis (AP) is an inflammatory disease of the pancreas that spans a wide range ranging from mild to critical forms. Contrary to the progress in the management of severe AP, the MAP has not presented significant changes in recent years. There are also no studies that establish a clear relationship between EEN in MAP and levels of albuminemia and CRP.A randomized, longitudinal and prospective clinical study

2019 Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) Controlled trial quality: uncertain

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