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Acute Otitis Media Observation

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1. Otitis media (acute): antimicrobial prescribing

Otitis media (acute): antimicrobial prescribing Otitis media (acute Otitis media (acute): antimicrobial ): antimicrobial prescribing prescribing NICE guideline Published: 28 March 2018 nice.org.uk/guidance/ng91 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration (...) be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Otitis media (acute): antimicrobial prescribing (NG91) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 21Contents Contents Overview 4 Who

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

2. Influenza vaccines for preventing acute otitis media in infants and children. (PubMed)

Influenza vaccines for preventing acute otitis media in infants and children. Acute otitis media (AOM) is one of the most common infectious diseases in children. It has been reported that 64% of infants have an episode of AOM by the age of six months and 86% by one year. Although most cases of AOM are due to bacterial infection, it is commonly triggered by a viral infection. In most children AOM is self limiting, but it does carry a risk of complications. Since antibiotic treatment increases (...) the risk of antibiotic resistance, influenza vaccines might be an effective way of reducing this risk by preventing the development of AOM.To assess the effectiveness of influenza vaccine in reducing the occurrence of acute otitis media in infants and children.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, CINAHL, LILACS, Web of Science, the WHO International Clinical Trials Registry Platform, and ClinicalTrials.gov (15 February 2017). We also searched

2017 Cochrane

3. Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study (PubMed)

Impact of Pediatric Acute Otitis Media on Child and Parental Quality of Life and Associated Productivity Loss in Malaysia: A Prospective Observational Study Acute otitis media (AOM) affects both child and parental quality of life (QoL). Data on QoL associated with AOM in Malaysia is sparse, and the burden of indirect costs have not been previously reported.To determine the effect of pediatric AOM on child and parental QoL in Malaysia and its economic impact (indirect costs).We utilized a set (...) of QoL questionnaires (PAR-AOM-QOL, OM-6, and EQ-5D) combined with questions addressing work/productivity loss and financial costs associated with caring for a child during his or her illness in an observational, multicenter, prospective study.One hundred and ten AOM patients aged ≤5 years were included in the analysis. The majority of respondents were the patient's mother. Parental QoL was negatively affected for both emotional and daily disturbance scales, but the level of disturbance was low

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2016 Drugs - real world outcomes

4. Adaptation of pain scales for parent observation: are pain scales and symptoms useful in detecting pain of young children with the suspicion of acute otitis media? (PubMed)

Adaptation of pain scales for parent observation: are pain scales and symptoms useful in detecting pain of young children with the suspicion of acute otitis media? The assessment of ear pain is challenging in young, mostly preverbal children. Our aim was to investigate whether pain scales are useful tools for parents to detect pain in their young children with the suspicion of acute otitis media (AOM), and to assess associations between 16 symptoms and the severity of pain.This cross-sectional (...) . Of symptoms, ear pain reported by child and restless sleep might indicate pain in children with respiratory tract infection. We suggest that the adaptation of pain scales for parent observation is a possibility in children with respiratory tract infection which, however, requires further studies.www.clinicaltrials.gov , identifier NCT00299455 . Date of registration: March 3, 2006.

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2018 BMC Pediatrics

5. Antibiotics for acute otitis media in children. (PubMed)

Antibiotics for acute otitis media in children. Acute otitis media (AOM) is one of the most common diseases in early infancy and childhood. Antibiotic use for AOM varies from 56% in the Netherlands to 95% in the USA, Canada and Australia. This is an update of a Cochrane review first published in The Cochrane Library in Issue 1, 1997 and previously updated in 1999, 2005, 2009 and 2013.To assess the effects of antibiotics for children with AOM.We searched CENTRAL (2015, Issue 3), MEDLINE (1966 (...) to April week 3, 2015), OLDMEDLINE (1958 to 1965), EMBASE (January 1990 to April 2015), Current Contents (1966 to April 2015), CINAHL (2008 to April 2015) and LILACS (2008 to April 2015).Randomised controlled trials (RCTs) comparing 1) antimicrobial drugs with placebo and 2) immediate antibiotic treatment with expectant observation (including delayed antibiotic prescribing) in children with AOM.Two review authors independently assessed trial quality and extracted data.For the review of antibiotics

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2015 Cochrane

6. Direction-Changing Positional Nystagmus in Acute Otitis Media Complicated by Serous Labyrinthitis: New Insights into Positional Nystagmus. (PubMed)

Direction-Changing Positional Nystagmus in Acute Otitis Media Complicated by Serous Labyrinthitis: New Insights into Positional Nystagmus. To demonstrate characteristic nystagmus findings in acute otitis media (AOM) complicated by serous labyrinthitis and discuss the mechanism of direction-changing positional nystagmus (DCPN) in this condition.A patient with AOM complicated by serous labyrinthitis on the left side.Video nystagmography and 3D fluid attenuated inversion recovery (FLAIR) magnetic (...) resonance imaging (MRI).Characterize positional nystagmus in a head-roll test observing the change of nystagmus direction in process of time and compare findings of temporal bone 3D FLAIR MRI.A previously healthy 50-year-old man who complained of acute otalgia, hearing loss, and vertigo was diagnosed with AOM complicated by serous labyrinthitis on the left side. A head-roll test performed on the day when vertigo developed showed persistent geotropic DCPN. While pre- and postcontrast T1-weighted MRI

2019 Otology and Neurotology

7. Otitis Media - Acute Otitis Media & Otitis Media with Effusion

Otitis Media - Acute Otitis Media & Otitis Media with Effusion Otitis Media: Acute Otitis Media (AOM) and Otitis Media with Effusion (OME) - Province of British Columbia theme_3_collection theme_3_frontend theme_3_collection theme_3_frontend Birth, Adoption, Death, Marriage & Divorce theme_1_collection theme_1_frontend theme_1_collection theme_1_frontend British Columbians & Our Governments theme_data_collection data_frontend theme_data_collection data_frontend Data theme_5_collection (...) theme_10_frontend theme_10_collection theme_10_frontend Sports, Recreation, Arts & Culture theme_8_collection theme_8_frontend theme_8_collection theme_8_frontend Taxes & Tax Credits theme_14_collection theme_14_frontend theme_14_collection theme_14_frontend Tourism & Immigration Search default_collection default_frontend Section Navigation Otitis Media: Acute Otitis Media (AOM) and Otitis Media with Effusion (OME) Effective Date: January 1, 2010 Recommendations and Topics Scope This guideline applies

2010 Clinical Practice Guidelines and Protocols in British Columbia

8. Supplemental Project to Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media

of or residing in the same household as another participan RCT: Randomized controlled trial; AOM: acute otitis media; DOB: date of birth; NR: not reported; OME: otitis media with effusion; MEE: middle ear effusion; TTP: tympanostomy tube placement Arm Details Table 3 shows the arm details information for the studies with both a registry record and papers. Again, the agreement between the record and the data extracted from the papers was, in general, well matched. One record, ISRCTN35793977, indicated a third (...) effusion persisted ISRCTN35793977 TT and adenoidectomy TT Observation and medical management MRC Multicentre Otitis Media Study Group 2012 (TARGET) 22443163 TT and adenoidectomy TT ISRCTN57358603 Early TT Watchful waiting for a period of nine months with analysis by intention to treat Maw 1999 10459904 TT within 6 weeks Watchful waiting for 9 months then TT if needed NCT00629694 TT and adenoidectomy Myringotomy and adenoidectomy Vlastos 2011 21205368 TT and adenoidectomy Myringotomy and adenoidectomy

2017 Effective Health Care Program (AHRQ)

9. Tympanostomy Tubes in Children with Otitis Media

and recurrent acute otitis media, summarize the frequency of adverse effects or complications associated with TT placement, synthesize information on the necessity for water precautions in children with TT, and assess the effectiveness of available treatments for otorrhea in children who have TT. Data sources. We conducted literature searches in MEDLINE ® , the Cochrane Central Trials Registry and Cochrane Database of Systematic Reviews, Embase ® , and CINAHL ® . Additionally, we perused the reference lists (...) palate or Down syndrome. Children with recurrent acute otitis media may have fewer episodes after TT placement, but the evidence base is limited and there is insufficient evidence to assess the impact on quality of life. The benefits of TT placement must be weighed against a variety of adverse events. There is no compelling evidence for children with TT to avoid swimming or bathing, or use earplugs or bathing caps. Should otorrhea develop, the evidence supports topical treatment rather than oral

2017 Effective Health Care Program (AHRQ)

10. Etiology of Acute Otitis Media in Children Less Than 5 Years of Age: A Pooled Analysis of 10 Similarly Designed Observational Studies. (PubMed)

Etiology of Acute Otitis Media in Children Less Than 5 Years of Age: A Pooled Analysis of 10 Similarly Designed Observational Studies. Acute otitis media (AOM) is an important cause of childhood morbidity and antibiotic prescriptions. However, the relative importance of the well-known otopathogens, Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu), remains unclear because of a limited number of tympanocentesis-based studies that vary significantly in populations sampled, case

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2016 Pediatric Infectious Dsease Journal

11. Acute Otitis Media Observation

Acute Otitis Media Observation Acute Otitis Media Observation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Acute Otitis Media (...) Observation Acute Otitis Media Observation Aka: Acute Otitis Media Observation , Observation Protocol for Acute Otitis Media Management From Related Chapters II. Background Most cases resolve without antibiotics Consider symptomatic treatment Antibiotics are more likely to cause side effects than speed symptomatic improvement for one not to have at 2-7 days: 20 for one to have adverse antibiotic effects ( , , rash): 14 (2013) Presc Lett 20(4): 20-21 III. Indications (with Informed Consent of parents) Age

2018 FP Notebook

12. Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish Children

, 2019 Sponsor: GlaxoSmithKline Information provided by (Responsible Party): GlaxoSmithKline Study Details Study Description Go to Brief Summary: The goal of this study is to look at the effect of pneumococcal conjugate vaccines (PCV) on physician-diagnosed otitis media (OM) and acute otitis media (AOM) incidence in Swedish children by collecting and analyzing patient level observational data already available in existing regional and national databases. Condition or disease Intervention/treatment (...) Acute Otitis Media Otitis Media Other: Data collection Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 1 participants Observational Model: Other Time Perspective: Retrospective Official Title: Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish Children Actual Study Start Date : June 16, 2016 Actual Primary Completion Date : May 18, 2017 Actual Study Completion Date : September 14, 2017 Resource links

2016 Clinical Trials

13. Systematic review and meta-analysis: Oral antibiotics confer small benefits and small harms in low-risk children with acute otitis media

Systematic review and meta-analysis: Oral antibiotics confer small benefits and small harms in low-risk children with acute otitis media Oral antibiotics confer small benefits and small harms in low-risk children with acute otitis media | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Oral antibiotics confer small benefits and small harms in low-risk children with acute otitis media Article Text Therapeutics Systematic review and meta

2014 Evidence-Based Medicine (Requires free registration)

14. Trends in Otitis Media Incidence After Conjugate Pneumococcal Vaccination; A National Observational Study. (PubMed)

Trends in Otitis Media Incidence After Conjugate Pneumococcal Vaccination; A National Observational Study. Pneumococcal conjugate vaccine (PCV) was introduced in 2000. The first 7-valent vaccine (PCV7) was followed by a 13-valent vaccine (PCV13) with the same conjugate, and a 10-valent vaccine (PCV10), conjugated to protein D from Haemophilus influenzae. The vaccines offer some protection against pneumococcal acute otitis media (AOM), and, with PCV10, possibly also some protection against H (...) . influenzae AOM. PCV7 was introduced in Sweden in 2009, but from 2010, Swedish counties were free to use either PCV13 or PCV10. The purpose of this study was to investigate the incidence of AOM-related diagnoses and surgical procedures before and after the introduction of PCV in Sweden, but also to compare the areas using PCV13 and PCV10.Data showing the number of AOM diagnoses, ventilation tube insertions, myringotomies, acute mastoiditis cases and mastoidectomies between 2005 and 2014 were extracted

2017 Pediatric Infectious Dsease Journal

15. Impact of acute otitis media clinical practice guidelines on antibiotic and analgesic prescriptions: a systematic review. (PubMed)

Impact of acute otitis media clinical practice guidelines on antibiotic and analgesic prescriptions: a systematic review. Clinical practice guidelines focusing on judicious use of antibiotics for childhood acute otitis media (AOM) have been introduced in many countries around the world.To systematically review the effects of these guidelines on the prescription of antibiotics and analgesics for children with AOM.Systematic searches of PubMed, Embase and Cochrane Library from inception to 6 June (...) and after guideline introduction. All studies had an observational design, using longitudinal data of children aged under 15 years (n=200-4.6 million) from either routine care, insurance databases or electronic surveys. Risk of bias of all studies was judged serious to critical.Of the five studies reporting on antibiotic prescription rates, three showed a decline of 5%-12% up to 3 years after guideline introduction and two found no or negligible effect. In one US study, the initial 9% decline decreased

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2018 Archives of Disease in Childhood

16. Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR)

Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR) Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR) (PROMAR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03614117 Recruitment Status : Recruiting First Posted : August 3

2018 Clinical Trials

17. Current management and referral patterns of pediatricians for acute otitis media. (PubMed)

Current management and referral patterns of pediatricians for acute otitis media. The American Academy of Pediatrics (AAP) has published an evidence-based clinical practice guideline for the management of acute otitis media (AOM), most recently revised in 2013. This study aims to assess current practice patterns and how they compare to the published guideline.An 11 question survey addressing topics included in the 2013 AAP AOM guidelines was mailed to 196 practicing pediatricians. Statistical (...) analysis was performed using Chi-square and ANOVA testing.76 (38%) completed surveys were returned. 75% of respondents were in group practice (non-academic) and 83% were in practice 11 years or more. 93% were members of the AAP. 46% of responding pediatricians use pneumatic otoscopy and/or tympanometry at least once a day to aid in the diagnosis of AOM, while 28% never do. 15% of respondents would choose close observation over antibiotics in a child under the age of 2 years with unilateral non-severe

2018 International Journal of Pediatric Otorhinolaryngology

18. Changes Over Time in Nasopharyngeal Colonization in Children Under 2 Years of Age at the Time of Diagnosis of Acute Otitis Media (1999–2014) (PubMed)

Changes Over Time in Nasopharyngeal Colonization in Children Under 2 Years of Age at the Time of Diagnosis of Acute Otitis Media (1999–2014) In children with acute otitis media (AOM), a decrease in nasopharyngeal (NP) colonization with vaccine serotypes of Streptococcus pneumoniae has been noted since the introduction of pneumococcal conjugate vaccines (PCVs). The purpose of this study is to describe corresponding changes in colonization with Haemophilus influenzae.In 4 separate studies, we (...) was observed, suggesting an impact of PCVs, the most recent prevalence rates of NP colonization with H. influenzae and ß-lactamase production were like those observed before universal administration of PCV7. This knowledge is critical to guide appropriate treatment recommendations for children with AOM.

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2018 Open forum infectious diseases

19. A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera (PubMed)

A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera Recurrent acute otitis media (rAOM, recurrent ear infection) is a common childhood disease caused by bacteria termed otopathogens, for which current treatments have limited effectiveness. Generic probiotic therapies have shown promise, but seem to lack specificity. We hypothesised that healthy children with no history of AOM carry protective commensal bacteria that could (...) fluids, middle ear rinses and ear canal swabs from the cases and nasopharyngeal swabs from both groups underwent 16S rRNA gene sequencing. The nasopharyngeal microbiomes of cases and controls were distinct. We observed a significantly higher abundance of Corynebacterium and Dolosigranulum in the nasopharynx of controls. Alloiococcus, Staphylococcus and Turicella were abundant in the middle ear and ear canal of cases, but were uncommon in the nasopharynx of both groups. Gemella and Neisseria were

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2018 BMC microbiology

20. Otitis Media with Effusion (OME)

of a 2004 guideline codeveloped by the American Academy of Otolaryngology—Head and Neck Surgery Foundation, the American Academy of Pediatrics, and the American Academy of Family Physicians, provides evidence-based recommendations to manage otitis media with effusion (OME), defined as the presence of fluid in the middle ear without signs or symptoms of acute ear infection. Changes from the prior guideline include consumer advocates added to the update group, evidence from 4 new clinical practice (...) . Abbreviations and Definitions of Common Terms. Table 1. Abbreviations and Definitions of Common Terms. About 2.2 million diagnosed episodes of OME occur annually in the United States at a cost of $4.0 billion. The indirect costs are likely much higher since OME is largely asymptomatic and many episodes are therefore undetected, including those in children with hearing difficulties or school performance issues. In contrast, acute otitis media (AOM) is the rapid onset of signs and symptoms of inflammation

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2016 American Academy of Otolaryngology - Head and Neck Surgery

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