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Acute Cholecystitis

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2. Endosonography-guided gallbladder drainage versus percutaneous cholecystostomy in very high-risk surgical patients with acute cholecystitis: an international randomised multicentre controlled superiority trial (DRAC 1) Full Text available with Trip Pro

Endosonography-guided gallbladder drainage versus percutaneous cholecystostomy in very high-risk surgical patients with acute cholecystitis: an international randomised multicentre controlled superiority trial (DRAC 1) Endosonography-guided Gallbladder Drainage Versus Percutaneous Cholecystostomy in Very High-Risk Surgical Patients With Acute Cholecystitis: An International Randomised Multicentre Controlled Superiority Trial (DRAC 1) - PubMed This site needs JavaScript to work properly. Please (...) Patients With Acute Cholecystitis: An International Randomised Multicentre Controlled Superiority Trial (DRAC 1) , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China anthonyteoh@surgery.cuhk.edu.hk. 2 Second Department of Internal Medicine, Wakayama Medical University, Wakayama, Wakayama, Japan. 3 Department of Gastroenterology and Hepatology, Tokyo Medical University Hospital, Tokyo, Japan. 4 Gastroenterology

2020 EvidenceUpdates

3. Differentiation of acute cholecystitis from chronic cholecystitis: Determination of useful multidetector computed tomography findings. Full Text available with Trip Pro

Differentiation of acute cholecystitis from chronic cholecystitis: Determination of useful multidetector computed tomography findings. The purpose of this study was to determine the diagnostic value of multidetector computed tomography (MDCT) imaging findings, to identify the most predictive findings, and to assess diagnostic performance in the diagnosis and differentiation of acute cholecystitis from chronic cholecystitis.In this retrospective study, we enrolled 382 consecutive patients (...) with pathologically proven acute or chronic cholecystitis who underwent computed tomography (CT) within 1 month before surgery. The CT findings were compared and logistic regression analysis was used to identify significant CT findings in predicting acute cholecystitis. Diagnostic performance of each CT finding and of combined findings was also assessed.Statistically significant CT findings distinguishing acute cholecystitis from chronic cholecystitis were increased gallbladder dimension (85.5% vs 50.6%, P < .001

2018 Medicine

4. Correction to: An Acute General Surgical Unit (AGSU) Negates the Impact of the Tokyo Guidelines 2018 (TG18) Diagnostic Criteria for the Treatment of Acute Cholecystitis. Full Text available with Trip Pro

Correction to: An Acute General Surgical Unit (AGSU) Negates the Impact of the Tokyo Guidelines 2018 (TG18) Diagnostic Criteria for the Treatment of Acute Cholecystitis. The original article can be found online.

2019 World Journal of Surgery

5. An Acute General Surgical Unit (AGSU) Negates the Impact of the Tokyo Guidelines 2018 (TG18) Diagnostic Criteria for the Treatment of Acute Cholecystitis. (Abstract)

An Acute General Surgical Unit (AGSU) Negates the Impact of the Tokyo Guidelines 2018 (TG18) Diagnostic Criteria for the Treatment of Acute Cholecystitis. The Tokyo Guidelines 2018 (TG18) were developed to aid diagnosis and treatment for acute cholecystitis. The benefits of being treated in an acute general surgical unit (AGSU) include earlier diagnosis and treatment. This study aims to define the usefulness of TG18 before and after the introduction of AGSU.Patients who underwent (...) cholecystectomy at Northern Health were audited retrospectively and assessed for TG18 diagnostic criteria and outcomes between 1 February 2012 and 1 February 2014 (one-year pre- and post-AGSU).Five hundred and eighty-seven patients underwent emergency cholecystectomy with 203 (34.6%) patients having a suspected diagnosis, and 234 (39.9%) patients with a definitive diagnosis of acute cholecystitis using TG18 diagnostic criteria. After the introduction of AGSU, time from imaging to operation improved from 2.5

2019 World Journal of Surgery

6. Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial. Full Text available with Trip Pro

Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial. To assess whether laparoscopic cholecystectomy is superior to percutaneous catheter drainage in high risk patients with acute calculous cholecystitis.Multicentre, randomised controlled, superiority trial.11 hospitals in the Netherlands, February 2011 to January 2016.142 high risk patients with acute calculous cholecystitis were (...) randomly allocated to laparoscopic cholecystectomy (n=66) or to percutaneous catheter drainage (n=68). High risk was defined as an acute physiological assessment and chronic health evaluation II (APACHE II) score of 7 or more.The primary endpoints were death within one year and the occurrence of major complications, defined as infectious and cardiopulmonary complications within one month, need for reintervention (surgical, radiological, or endoscopic that had to be related to acute cholecystitis

2018 BMJ Controlled trial quality: predicted high

7. Long-term outcomes of acute acalculous cholecystitis treated by non-surgical management. Full Text available with Trip Pro

Long-term outcomes of acute acalculous cholecystitis treated by non-surgical management. Although cholecystectomy is generally recommended for acute acalculous cholecystitis (AAC) treatment, non-surgical management can be considered in patients at a high risk for surgery. This study compared outcomes of surgical and non-surgical management and analyzed the long-term outcomes of AAC patients managed non-surgically.We retrospectively analyzed 89 patients diagnosed with AAC between January 1, 2007

2020 Medicine

8. Comparison of endoscopic naso-gallbladder drainage and percutaneous transhepatic gallbladder drainage in acute suppurative cholecystitis: Study Protocol Clinical Trial (SPIRIT Compliant). Full Text available with Trip Pro

Comparison of endoscopic naso-gallbladder drainage and percutaneous transhepatic gallbladder drainage in acute suppurative cholecystitis: Study Protocol Clinical Trial (SPIRIT Compliant). Transitional drainage, which is followed by cholecystectomy plays a key role in the management of acute cholecystitis, especially in high-risk surgical patients. Endoscopic naso-gallbladder drainage (ENGBD) is an alternative to percutaneous transhepatic gallbladder drainage (PTGBD) for patients who need (...) temporary drainage. There is a lack of prospective comparison on the relevant outcomes of the two drainage methods during the period of drainage, especially the subsequent cholecystectomy.This is a randomized controlled two-arm non-blind single center trial. Patients with acute cholecystitis undergo emergent or early cholecystectomy and need drainage will be randomly assigned to group PTGBD or ENGBD. Pain score is defined as the primary endpoint, whereas several secondary endpoints, such as the rates

2020 Medicine

9. Percutaneous cholecystostomy - An option in selected patients with acute cholecystitis. Full Text available with Trip Pro

Percutaneous cholecystostomy - An option in selected patients with acute cholecystitis. While urgent percutaneous cholecystostomy (PC) was introduced as an alternative to acute surgical treatment for acute cholecystitis (AC), the current place of PC in the treatment algorithm for AC is challenged. We evaluate demographics and outcomes of PC in routine clinical practice in a population-based cohort.Retrospective evaluation of consecutive patients treated with PC for AC between 2000 and 2015 (...) . The severity of cholecystitis was graded according to the 2013 Tokyo Guidelines.One hundred forty-nine patients were included (82; 55% males) (median age of 72.5 years; range, 21-92). The Tokyo Guidelines criteria of 2013 (TG13) severity grade distribution was 4%, 61.7%, and 34.2% for grades I, II, and III, respectively. No difference was observed between males and females with regard to age, American Society of Anesthesiologists (ASA) score, comorbidities, or previous history of cholecystitis. PC

2020 Medicine

10. Surgical treatment of acute calculous cholecystitis complicated with hepatic dysfunction. Full Text available with Trip Pro

Surgical treatment of acute calculous cholecystitis complicated with hepatic dysfunction. To evaluate the timing, feasibility, and necessity of early laparoscopic cholecystectomy (LC) in the management of patients with acute calculous cholecystitis complicated with hepatic dysfunction.The clinical data of 60 patients with acute calculous cholecystitis complicated with hepatic dysfunction treated from January 2016 to January 2018 were analyzed retrospectively. A total of 32 patients underwent LC (...) and fewer hospital costs (P < .05). All the patients were cured.It is safe, feasible, and necessary to perform LC within 72 hours in patients with acute calculous cholecystitis complicated with hepatic dysfunction. Such patients show a high positive correlation between the inflammation of acute calculous cholecystitis and the damage of hepatic function.

2020 Medicine

11. Retrospective Analysis of Outcomes Following Percutaneous Cholecystostomy for Acute Cholecystitis. (Abstract)

Retrospective Analysis of Outcomes Following Percutaneous Cholecystostomy for Acute Cholecystitis. Percutaneous cholecystostomy (PC) is often performed for patients with acute cholecystitis who are too high risk for cholecystectomy. The purpose of this retrospective study was to evaluate the outcomes of this cohort of patients over a 5-year period.A retrospective analysis of all patients treated with PC for acute cholecystitis in a tertiary centre teaching hospital was conducted. The study

2020 World Journal of Surgery

12. Is out-of-hours cholecystectomy for acute cholecystitis associated with complications? Full Text available with Trip Pro

Is out-of-hours cholecystectomy for acute cholecystitis associated with complications? Existing data on the safety of out-of-hours cholecystectomy are conflicting. The aim of this study was to investigate whether out-of-hours cholecystectomy for acute cholecystitis is associated with a higher risk for complications compared with surgery during office hours.This was a population-based cohort study. The Swedish Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography Register (...) (GallRiks) was used to investigate the association between out-of-hours cholecystectomy for acute cholecystitis and complications developing within 30 days. Data from patients who underwent cholecystectomy between 2006 and 2017 were collected. Out-of-hours surgery was defined as surgery commencing between 19.00 and 07.00 hours on weekdays, or any time at weekends (Friday 19.00 hours to Monday 07.00 hours). Multivariable logistic regression analysis was used to assess the risk of complications, with time

2020 British Journal of Surgery

13. Comparison of laparoscopic cholecystectomy and delayed laparoscopic cholecystectomy in aged acute calculous cholecystitis: a cohort study. (Abstract)

Comparison of laparoscopic cholecystectomy and delayed laparoscopic cholecystectomy in aged acute calculous cholecystitis: a cohort study. In elderly patients with calculous acute cholecystitis, the risk of emergency surgery is high, and percutaneous cholecystostomy tube drainage (PC) combined with delayed laparoscopic cholecystectomy (DLC) may be a good choice. We retrospectively compared laparoscopic cholecystectomy (LC) to DLC after PC to determine which is the better treatment strategy.We (...) performed a retrospective cohort analysis of 752 patients with acute calculous cholecystitis. Patients with the following conditions were included: (1) age > 65 years old; (2) patients with a grade 2 or 3 severity of cholecystitis according to the 2013 Tokyo Guidelines (TG13); (3) the surgeons who performed the LC were professors or associate professors and (4) the DLC was performed in our hospital after PC. Patients who missed their 30-day follow-up; were diagnosed with bile duct stones, cholangitis

2020 Surgical endoscopy

14. Safety and feasibility of prolonged versus early laparoscopic cholecystectomy for acute cholecystitis: a single-center retrospective study. Full Text available with Trip Pro

Safety and feasibility of prolonged versus early laparoscopic cholecystectomy for acute cholecystitis: a single-center retrospective study. Laparoscopic cholecystectomy (LC) is the standard treatment for acute cholecystitis (AC), and it should be performed within 72 h of symptoms onset if possible. In many undesired situations, LC was performed beyond the golden 72 h. However, the safety and feasibility of prolonged LC (i.e., performed more than 72 h after symptoms onset) are largely unknown

2020 Surgical endoscopy

15. Evaluation of the CT Scan as the First Examination for the Diagnosis and Therapeutic Strategy for Acute Cholecystitis. (Abstract)

Evaluation of the CT Scan as the First Examination for the Diagnosis and Therapeutic Strategy for Acute Cholecystitis. The CT scan has supplanted the abdominal ultrasound for emergency examinations. A comparison of CT scan and ultrasound performance for the diagnosis and management of acute cholecystitis in acute care was proposed. The hypothesis is that the CT scan may be sufficient for the diagnosis of acute cholecystitis, which would allow faster progress to surgery.The retrospective study (...) of consecutive patients operated for acute cholecystitis or gallbladder distension with pre-operative imaging within 48 h in one centre.Between 2015 and 2017, a total of 341 cholecystectomies were performed in our centre. The analysis involved 120 patients. Ultrasound had better sensitivity than the CT scan, respectively, 79.4% [70.5-86.6] and 52.3% [42.5-62.1], but less specificity, with 61.5% [31.6-86.1] and 92.3% [64.0-99.8], respectively. However, there was a significant difference in favour of the CT

2020 World Journal of Surgery

16. Cholecystitis

examination findings. Ultrasound is the definitive initial test; hepatobiliary iminodiacetic acid (HIDA) scanning and MRI may be helpful in cases where diagnosis is unclear. Treatment is early cholecystectomy. Definition Acute cholecystitis is acute gallbladder inflammation, and one of the major complications of cholelithiasis or gallstones. It develops in up to 10% of patients with symptomatic gallstones. Ziessman HA. Acute cholecystitis, biliary obstruction and biliary leakage. Semin Nucl Med. 2003 Oct (...) ;33(4):279-96. http://www.ncbi.nlm.nih.gov/pubmed/14625840?tool=bestpractice.com In most cases (90%), it is caused by complete cystic duct obstruction usually due to an impacted gallstone in the gallbladder neck or cystic duct, which leads to inflammation within the gallbladder wall. Ziessman HA. Acute cholecystitis, biliary obstruction and biliary leakage. Semin Nucl Med. 2003 Oct;33(4):279-96. http://www.ncbi.nlm.nih.gov/pubmed/14625840?tool=bestpractice.com In 5% of cases, bile inspissation

2018 BMJ Best Practice

17. Performance of the Choledocholithiasis Diagnostic Score in Patients with Acute Cholecystitis Full Text available with Trip Pro

Performance of the Choledocholithiasis Diagnostic Score in Patients with Acute Cholecystitis The prevalence of choledocholithiasis among patients with acute cholecystitis is estimated to be between 9 and 16.5%. There are no validated algorithms to predict choledocholithiasis in this group of patients.The aim of this study was to evaluate the performance of the choledocholithiasis diagnostic score proposed by the American Society for Gastrointestinal Endoscopy, in patients with acute (...) cholecystitis.A retrospective cross-sectional study, covering a 4-year period at a secondary care hospital, was performed. All patients with an encoded diagnosis of acute cholecystitis and with at least one of the following procedures were included: endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasound, magnetic resonance cholangiopancreatography, and intraoperative cholangiography.Among 4,369 patients with the diagnosis of acute cholecystitis, 40 (0.92%) had clinical or sonographic

2017 GE Portuguese journal of gastroenterology

18. Systematic review with meta analysis: Early laparoscopic cholecystectomy appears better than delayed laparoscopic cholecystectomy for patients with acute cholecystitis

Systematic review with meta analysis: Early laparoscopic cholecystectomy appears better than delayed laparoscopic cholecystectomy for patients with acute cholecystitis Early laparoscopic cholecystectomy appears better than delayed laparoscopic cholecystectomy for patients with acute cholecystitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more (...) cholecystectomy for patients with acute cholecystitis Article Text Therapeutics/Prevention Systematic review with meta analysis Early laparoscopic cholecystectomy appears better than delayed laparoscopic cholecystectomy for patients with acute cholecystitis Kurinchi Gurusamy Statistics from Altmetric.com Commentary on : Wu XD , Tian X , Liu MM , et al . Meta-analysis comparing early versus delayed laparoscopic cholecystectomy for acute cholecystitis . Context Acute cholecystitis, also known as inflammation

2016 Evidence-Based Medicine

19. Acute Hepatitis B with Pancreatitis and Cholecystitis Leading to Acute Liver Failure and Death Full Text available with Trip Pro

Acute Hepatitis B with Pancreatitis and Cholecystitis Leading to Acute Liver Failure and Death Acute liver failure is defined as severe acute liver injury, concurrent with encephalopathy and loss of hepatic synthetic function, in a patient without known pre-existing liver disease. Evaluation of acute liver failure in the emergency department should focus on identification of treatable causes. Acute liver failure from acute hepatitis B infection is a rare but potentially lethal occurrence. Multi (...) -organ dysfunction from acute liver failure may be exacerbated by metabolic and inflammatory reactions associated with acute pancreatitis, which accompanies approximately 5% of cases of acute viral hepatitis. Transplant-free survival rate with liver failure from acute hepatitis B is unfortunately less than 20%.

2018 Clinical Practice and Cases in Emergency Medicine

20. Acute Acalculous Cholecystitis due to primary acute Epstein-Barr virus infection treated with laparoscopic cholecystectomy; a case report Full Text available with Trip Pro

Acute Acalculous Cholecystitis due to primary acute Epstein-Barr virus infection treated with laparoscopic cholecystectomy; a case report Epstein Barr virus (EBV) is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic EBV shedders. It usually presents with fever, pharyngitis and lymphadenopathy. Majority of individuals with primary EBV infection recover uneventfully. Acute Acalculous Cholecystitis (AAC) is usually seen in hospitalized (...) and critically ill patients with major trauma, shock, severe sepsis, total parenteral nutrition and mechanical ventilation.We report a 25-year- old woman presented with acute Epstein-Barr Virus (EBV)infection and hepatobiliary iminodiacetic acid (HIDA) scan confirmed presence of Acute Acalculous Cholecystitis (AAC). Conservative management was advised initially, but she had a laparoscopic cholecystectomy due to intolerable abdominal pain.AAC is a rare complication of acute EBV infection and it is usually

2018 Annals of Medicine and Surgery

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