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form may develop after acuteangleclosure where synechial closure of the angle persists. It may also develop over time, as the angle closes from prolonged or repeated contact between the peripheral iris and the trabecular meshwork, which often leads to peripheral anterior synechiae (PAS) and functional damage to the angle. History and exam presence of risk factors halos around lights aching eye or brow pain headache nausea, vomiting reduced visual acuity eye redness elevatedintraocularpressure (...) Angle-closureglaucomaAngle-closureglaucoma - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search Angle-closureglaucoma Last reviewed: February 2019 Last updated: March 2018 Summary Acuteangle-closureglaucoma is an urgent but uncommon, dramatic symptomatic event with blurring of vision, painful red eye, headache, nausea, and vomiting. Diagnosis is made by noting high intra-ocular pressure, corneal oedema, shallow
Optic disc melanocytoma with normal tension glaucoma and angleclosureglaucoma: Two case reports. Optic disc melanocytoma is an ophthalmic tumor that arises from melanocytes, and is a variant of the melanocytic nevus. Here we report 2 cases of optic disc melanocytoma in Asian patient: one associated with normal tension glaucoma (NTG), and the other associated with angleclosureglaucoma (ACG).Case 1 is a 57-year-old Asian female presented to our department for a general ophthalmic examination (...) examination revealed shallow anterior chamber. Under the impression of intermittent angleclosure attack, prophylactic laser peripheral iridotomy were performed. On dilated fundus examination, black pigmented lesion was found at superior sector of optic disc. Further examination revealed bilateral superotemporal, inferotemporal RNFL thinning on OCT, and spatially corresponding visual field defects.Clinical diagnosis of NTG was made for case 1 patient. Although it was a little distant from typical
-Blanco A, Munoz B, Friedman DS, Foster PJ. The prevalence of primary angleclosureglaucoma in European derived populations: a systematic review. Br J Ophthalmol. 2012;96(9):1162-7 Hui X, Michelessi M. Medical interventions for treating primary angle-closureglaucoma. Cochrane Database of Systematic Reviews 2015;12:CD012001 Lachkar Y, Bouassida W. Drug-induced acuteangleclosureglaucoma Curr Opin Ophthalmol 2007;18:129-33 Napier ML, Azuara-Blanco A. Changing patterns in treatment of angleclosure (...) glaucoma. Curr Opin Ophthalmol. 2018;29(2):130-4 Rich R. The pilocarpine paradox. Journal of Glaucoma. 1996;5:225-7 Lay summary Primary AngleClosureGlaucoma (PACG) is rarer in this country than Primary Open Angle Glaucoma, and in its acute form differs in that the drainage route for the fluid inside the eye is closed off, rather than gradually blocked. It affects women more often than men, is commoner in long-sighted people and people of East Asian ancestry, and becomes more likely to occur as people
, and narrow irido-corneal angles. 6 As people age, their anterior chamber becomes more shallow and the lens thickens and moves anteriorly, 5 which makes this condition rare below the age of forty, with the peak incidence occurring in the sixth and seventh decades of life. 8 Physical Examination Patients with acuteangleclosureglaucoma present with conjunctival injection and a fixed, mid-dilated pupil measuring 5-6 mm in diameter. 9 Due to the elevatedintraocularpressure, the eye may feel hard (...) Medical Concepts: AcuteAngleClosureGlaucomaAcuteAngleClosureGlaucoma Review - CanadiEM Medical Concepts: AcuteAngleClosureGlaucoma In by Stephanie Cargnelli October 11, 2016 A 62 year old woman presents to your Emergency Department with a chief complaint of severe right eye pain. Upon further questioning, she reveals reduced vision in the affected eye and colored halos around lights. She reports a diffuse headache and two episodes of vomiting. A quick physical exam reveals significant
with a diagnosis of low grade ciliary body melanoma. This patient experienced eventual mechanical angleclosure with a CWS appearing in the posterior pole in the setting of acute elevation of intraocular pressure (IOP). This eye underwent enucleation and pathology evaluation.Fundus photography documented a CWS in the posterior segment during a period of acute elevation in IOP. Subsequently the eye was enucleated due to pain from refractory angleclosureglaucoma secondary to low grade iris-ciliary body ring (...) in the setting of acute elevations of IOP and may be associated with loss of nerve fiber layer. This loss of nerve fiber layer can confound the ability to judge glaucoma progression based on nerve fiber layer thickness via optical coherence tomography and changes in disc contours. Patient care may benefit from care provider's awareness of this possible phenomenon in the setting of angleclosure.
Association of Gabapentin or Pregabalin Use and Incidence of AcuteAngle-closureGlaucoma. Gabapentin and its derivatives have numerous indications and are commonly prescribed medications. In this article, we provide evidence of a link between gabapentinoid use and incidence of acuteangle-closure glaucoma.Gabapentinoids, such as gabapentin and pregabalin, are commonly prescribed classes of drugs in North America. We sought to determine the association of gabapentin or pregabalin use (...) and the incidence of acuteangle-closure glaucoma.This was a nested case-control study. All adult patients who developed acuteangle-closureglaucoma between January 1, 2006 and December 31, 2016, and enrolled in the PharMetrics Plus database were eligible for inclusion. A conditional logistic regression model was constructed to assess the association between gabapentin or pregabalin use and the incidence of acuteangle-closure glaucoma.Incidence of acuteangle-closureglaucoma was found to be statistically
Differences between fellow eyes of acute and chronic primary angleclosure (glaucoma): An ultrasound biomicroscopy quantitative study. To compare various biometric parameters between fellow eyes of acute primary angleclosure (glaucoma) [APAC(G)] and fellow eyes of chronic primary angleclosure (glaucoma) [CPAC(G)].Ultrasound biomicroscopy examinations were performed on 47 patients with unilateral APAC(G) and 41 patients with asymmetric CPAC(G) before laser peripheral iridotomy and pilocarpine (...) ), as well as larger LV (P = 0.002), IC (P = 0.012), and IRD (P = 0.003). On multivariate logistic regression analyses, a 0.1 mm decrease in ACD (odds ratio [OR]: 0.705, 95%CI: 0.564-0.880, P = 0.002), ICPD (OR: 0.557, 95%CI: 0.335-0.925, P = 0.024), and a 0.1 mm increase in IRD (OR: 2.707, 95%CI: 1.025-7.149, P = 0.045), was significantly associated with occurrence of acute angle closures.Fellow eyes of APAC(G) had smaller anterior segment dimensions, higher LV, more posterior iris insertion, greater IC
A Convergence of Ophthalmic and Life-threatening Emergencies: AcuteAngleClosureGlaucoma and Subarachnoid Hemorrhage. To report a unique case of acuteangleclosureglaucoma in the setting of a subarachnoid hemorrhage due to a ruptured cerebral aneurysm.Observational case report and review of the literature.A 75-year-old woman presented with blurry vision, nausea, vomiting, and left eye pain. She was found to have a complete third nerve palsy, with ptosis, exotropia, hypotropia, and a fixed (...) mydriasis with resultant acuteangleclosureglaucoma. Pilocarpine was initiated, and neuroimaging revealed a subarachnoid hemorrhage from a ruptured posterior communicating artery aneurysm. The aneurysm was successfully coiled, and outpatient laser iridotomies were subsequently performed. Only 4 prior cases of acuteangleclosureglaucoma in the setting of a third nerve palsy have been reported in the literature. To our knowledge, this case is the first report of angleclosureglaucoma in the setting
-closureglaucoma (PACG), acute primary angleclosure (APAC), primary open-angle glaucoma (POAG), pigmentary glaucoma (PG) and pseudoexfoliative glaucoma (PXG) from 111 hospitals covering 67 cities from 22 provinces, 4 municipalities, and 5 autonomous regions in mainland China. Clinical data were collected using an Electronic Data Capture System designed by Tongren hospital and Gauss informed Ltd. Blood samples were collected from every patient for further genetic analysis.Medical records of 10892 (...) . At the national level, there are few reports on the current medical practice for glaucoma patients. Chinese Glaucoma Study Consortium (CGSC) will be considered as the first nation-wide glaucoma registry in China. Here we describe its design, rationale, the geographic distribution of the hospitals, and baseline patient characteristics.From December 21st 2015 to September 9th 2018, CGSC recruited patients with the diagnoses of primary angle-closure suspect (PACS), primary angle-closure (PAC), primary angle
An unusual case of acuteangle-closureglaucoma following deep anterior lamellar keratoplasty using the â€œbig bubbleâ€ technique To report the first case of acuteangleclosure due to a high-pressure Descemet membrane detachment following deep anterior lamellar keratoplasty (DALK) using the "big bubble" technique.A 25-year-old man underwent DALK surgery for keratoconus using the "big bubble" technique in which an air bubble is injected in deep stroma to promote dissection of underlying (...) Descemet membrane from stroma. Surgery was uneventful and the patient was discharged home in good conditions. On post-operative day 1, the patient came back with severe periocular pain. Intra-ocular pressure was found to be 38 mmHg. Anterior-segment OCT revealed a "double anterior chamber" created by a high-pressure Descemet detachment that was occluding the pupil and causing secondary acuteangleclosureglaucoma. The patient was brought back promptly to the operating room where the high-pressure
The Seasonality of Acute Attack of Primary Angle-ClosureGlaucoma in Beijing, China In this study, the seasonality of acute attack of primary angle-closureglaucoma (PACG) was analysed. This retrospective case series included 283 patients (200 women, 83 men; mean age, 68.2 ± 10.3 years; range, 37-96 years) with acute attack of PACG from a university-based clinic over 4 years. Patients' age and sex, and the date and season of onset of PACG attack, were analysed. Descriptive analysis and von (...) Mises distribution were used for statistical analysis. The highest incidence of acute attack of PACG was observed in those aged 60-69 years (34.6%). Descriptive analysis showed that the incidence was greater in June and July for men, November for women, and November for the entire sample. An angular plot (using von Mises distribution) of the individual dates of onset revealed the estimated peak onset on September 11, November 8, and October 28 for men, women, and both, respectively. Integration
A Novel Association between Oxybutynin Use and Bilateral AcuteAngleClosureGlaucoma: A Case Report and Literature Review We are reporting a case of a 62-year-old male presenting with headache and blurry vision. His condition resolved with cessation of the presumed offending medication and urgent bilateral laser peripheral iridotomies since he failed medical therapy. This case presents a novel association between oxybutynin and bilateral acuteangle-closureglaucoma (AACG).
Acuteangleclosureglaucoma â€“ A potential blind spot in critical care We report a case of a 69-year-old gentleman who developed an acutely painful eye with loss of visual acuity whilst on the critical care unit. He was admitted three days previously with an infective exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation. In addition, he received intravenous antibiotics, steroids, nebulised bronchodilators and intravenous aminophylline, together (...) with noradrenaline for blood pressure support. On development of visual symptoms, an emergency ophthalmology review diagnosed acuteangleclosureglaucoma. Treatment with pilocarpine eye drops, intravenous acetazolamide and bilateral YAG laser iridotomies provided immediate symptom relief and he went on to make an excellent recovery. Acuteangleclosureglaucoma is a potentially devastating ophthalmic emergency. Critical care patients are at particular risk for the development of this condition due to the use
Endoscopic Goniosynechialysis for AcuteAngleClosureGlaucoma Following Descemetâ€™s Stripping Automated Endothelial Keratoplasty We describe a new modified technique to release the peripheral iridocorneal adhesions that formed after Descemet stripping automated endothelial keratoplasty. The usual technique of goniosynechialysis was modified and performed using endoscopic fiber-optic light and camera probe to aid visualization of the adherent iris tissue and carry out uneventful 270 degrees (...) and improved quality of life. How to cite this article: Rana M, Shah S, Pandey P, Masood I. Endoscopic Goniosynechialysis for AcuteAngleClosureGlaucoma Following Descemet's Stripping Automated Endothelial Keratoplasty. J Curr Glaucoma Pract 2018;12(2):90-93.
AcuteAngle-ClosureGlaucoma Caused by Venlafaxine 29893371 2018 12 11 2018 12 11 2542-5641 131 12 2018 Jun 20 Chinese medical journal Chin. Med. J. AcuteAngle-ClosureGlaucoma Caused by Venlafaxine. 1502-1503 10.4103/0366-6999.233952 Zhou Nan N Department of Pharmacy, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, China. Zhao Jia-Xin JX Department of Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, China. Zhu Ya-Ning YN Department of Pharmacy, Shaanxi (...) Provincial People's Hospital, Xi'an, Shaanxi 710068, China. Zhang Peng P Department of Pharmacy, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, China. Zuo Yan Y Department of Pharmacy, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, China. eng Letter China Chin Med J (Engl) 7513795 0366-6999 0 Antidepressive Agents, Second-Generation 7D7RX5A8MO Venlafaxine Hydrochloride IM Acute Disease Antidepressive Agents, Second-Generation adverse effects Glaucoma, Angle-Closure chemically
Bilateral acuteangle-closureglaucoma following tramadol subcutaneous administration. To report a case of bilateral acuteangleclosure-glaucoma following the use of subcutaneous Tramadol.A 42-year-old healthy man with unremarkable past medical and ocular history, was admitted to the Orthopedic Department for surgical treatment of a bilateral open fracture of the femur following a road accident. Three hoursafterTramadolsubcutaneous injection, the patient complained of a bilateral acute painful (...) visual loss with persistent vomiting. An ocular examination showed bilateral acuteangle-closure-glaucoma. The patient was treated with topical anti-glaucoma therapy and intravenous Mannitol 20%.After resolution of ocular hypertension attack, NdYag laser peripheral iridotomy was performed on both eyes. After a follow-up period of 7 days visual acuity improved to 20/20 in both eyes and intraocular pressure returned to normal levels.This case highlights the risk of developing bilateral acuteangle
AcuteAngle-closureGlaucoma Associated With Aripiprazole in the Setting of Plateau Iris Configuration. The purpose of this study was to report a novel case of drug-induced angle-closure from aripiprazole (Abilify), an atypical antipsychotic, and propose a mechanism for this association.We report a case of a 45-year-old white woman who presented in subacute angleclosure 2 months after initiating aripiprazole 5 mg daily for depression. This patient reported no prior ocular history and had been (...) of the angles in both eyes 1 week after cessation.This is the first report to describe drug-induced angle-closureglaucoma associated with aripiprazole use. The mechanism of angleclosure, we hypothesize, is from mydriasis and/or supraciliary effusion mediated by the serotoninergic effect on the iris and ciliary body complex. Treatment is preferably cessation of the medication. However, in cases where the medication is necessary for management of major depression, iridoplasty should be performed to reduce
glaucoma, primary and secondary angleclosureglaucoma Condition after previous glaucoma incisional surgery IOP > 40 mmHg Myopia (> -6 dpt) or hypermetropia (> +4 dpt) Axis length < 22 mm or > 26 mm Exudative age-related macular degeneration, instable macular degeneration 30 days prior to inclusion, or macular edema Acute retinal detachment Uncontrolled Diabetes Mellitus (DM) with manifestation of moderate to severe non-proliferative diabetic Retinopathy (DR) or proliferative DR. History or evidence (...) Performance and Safety of the ARGOS-SC01 Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma Surgery Performance and Safety of the ARGOS-SC01 Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save
reduce the risk of vision loss and therefore improve quality of life. Vision loss may be classified as a disability which is a protected characteristic defined in the Equality Act (2010). Improved management of IOP may reduce the risk of vision loss and therefore improve quality of life. People of African-Caribbean family origin are at increased risk of COAG. People of Asian family origin are at increased risk of acuteangle-closureglaucoma. Evidence re Evidence review view Clinical and technical (...) The SENSIMED Triggerfish contact lens sensor for continuous 24-hour recording of ocular dimensional changes in people with or at risk of developing glaucoma The SENSIMED T The SENSIMED T riggerfish contact lens sensor riggerfish contact lens sensor for continuous 24-hour recording of ocular for continuous 24-hour recording of ocular dimensional changes in people with or at risk of dimensional changes in people with or at risk of de dev veloping glaucoma eloping glaucoma Medtech innovation