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Actinic Keratoses

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41. High Patient Satisfaction with Daylight-Activated Methyl Aminolevulinate Cream in the Treatment of Multiple Actinic Keratoses: Results of an Observational Study in Australia (PubMed)

High Patient Satisfaction with Daylight-Activated Methyl Aminolevulinate Cream in the Treatment of Multiple Actinic Keratoses: Results of an Observational Study in Australia Actinic keratoses (AK) are treated to reduce the risk of progression to squamous cell carcinoma and for symptomatic and cosmetic benefits. The objective of this observational study was to generate real-life data on the use of daylight photodynamic therapy with methyl aminolevulinate cream (MAL DL-PDT) in treating mild

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2017 Dermatology and therapy

42. Pharmacoeconomy of drugs used in the treatment of actinic keratoses (PubMed)

Pharmacoeconomy of drugs used in the treatment of actinic keratoses Actinic keratosis (AK) represents an emerging issue in the area of skin diseases which undergo high risk for developing squamous cell carcinoma (SCC). Recently, evidence has been accumulated that 3% diclofenac sodium and ingenol mubetate may efficiently counteract the development of progressive AK even if the pharmacoeconomic impact of such a treatment remains poorly defined. With the objective of assessing the efficacy of 3

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2016 International journal of immunopathology and pharmacology

43. Improved patient satisfaction using ingenol mebutate gel 0.015% for the treatment of facial actinic keratoses: a prospective pilot study (PubMed)

Improved patient satisfaction using ingenol mebutate gel 0.015% for the treatment of facial actinic keratoses: a prospective pilot study Actinic keratoses (AKs), especially on areas of the face, have a negative impact on a patient's quality of life (QoL). These lesions manifest on sun-damaged skin and have the potential to progress to squamous cell carcinoma. Field-directed therapy alone and in combination with lesion-directed treatment is effective in clearing both visible and nonvisible AK

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2016 Clinical, cosmetic and investigational dermatology

44. Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States

Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States (DaylightPDT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02867722

2016 Clinical Trials

45. Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy

Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02990221 Recruitment Status : Active, not recruiting First Posted : December 13, 2016 Last Update Posted : January 8, 2018 Sponsor: University

2016 Clinical Trials

46. Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses

Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02952898 Recruitment Status : Completed First Posted : November 2, 2016 Results First Posted : January 10, 2019 Last Update Posted : January 10

2016 Clinical Trials

47. Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin

Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03006185 Recruitment Status : Completed First Posted : December 30, 2016 Last Update Posted : July 13

2016 Clinical Trials

48. Effect of a Pre-Treatment Educational Video in Improving Patient Satisfaction with 5-Fluorouracil Treatment for Actinic Keratoses: A Randomized Controlled Trial. (PubMed)

Effect of a Pre-Treatment Educational Video in Improving Patient Satisfaction with 5-Fluorouracil Treatment for Actinic Keratoses: A Randomized Controlled Trial. Patient treatment satisfaction and adherence may be affected by the initial understanding of outcomes in the treatment of actinic keratoses with 5-fluorouracil 5% cream (5-FU). Pre-treatment educational videos may optimize this understanding. The objective of this study was to determine whether prospective patient viewing (...) of an educational video delineating treatment effects and expectations improves patient satisfaction and treatment completion rates for the treatment of actinic keratoses with 5-FU.Forty-four participants were recruited to the UC Davis Dermatology outpatient clinic. Each participant was randomized to the video (group A) or control group (group B), and topical 5-FU cream treatment was conducted for 2 weeks in both groups.A follow-up questionnaire was performed to assess patient satisfaction and adherence

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2016 Dermatology and therapy

49. Microneedling Prior to Levulan PDT for the Treatment of Actinic Keratoses: A Split-Face, Blinded Trial. (PubMed)

Microneedling Prior to Levulan PDT for the Treatment of Actinic Keratoses: A Split-Face, Blinded Trial. Photodynamic Therapy (PDT) with topical Levulan is an approved and efficacious method for treating actinic keratoses. This therapy depends on the ability of the Levulan (delta amino levulinic acid) to penetrate the stratum corneum and enter the cells of the epidermis. Microneedling is an increasing popular cosmetic therapy in which an array of tiny needles is used to make holes

2016 Journal of drugs in dermatology : JDD

50. Microneedles assisted incubation during aminolevulinic acid photodynamic therapy of actinic keratoses - a randomized controlled evaluator blind trial. (PubMed)

Microneedles assisted incubation during aminolevulinic acid photodynamic therapy of actinic keratoses - a randomized controlled evaluator blind trial. 27730625 2017 10 31 2017 10 31 1365-2133 176 2 2017 02 The British journal of dermatology Br. J. Dermatol. Microneedle-assisted incubation during aminolaevulinic acid photodynamic therapy of actinic keratoses: a randomized controlled evaluator-blind trial. 543-545 10.1111/bjd.15116 Lev-Tov H H Department of Dermatology and Cutaneous Surgery (...) Controlled Trial 2016 12 22 England Br J Dermatol 0004041 0007-0963 0 Photosensitizing Agents 88755TAZ87 Aminolevulinic Acid IM Aged Aged, 80 and over Aminolevulinic Acid administration & dosage Equipment Design Facial Dermatoses drug therapy Female Forehead Humans Keratosis, Actinic drug therapy Male Middle Aged Needles Pain etiology Pain Measurement Photochemotherapy instrumentation Photosensitizing Agents administration & dosage Prospective Studies Single-Blind Method 2016 10 13 6 0 2017 11 1 6 0 2016

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2016 British Journal of Dermatology

51. Optical coherence tomography of actinic keratoses and basal cell carcinomas - differentiation by quantification of signal intensity and layer thickness. (PubMed)

Optical coherence tomography of actinic keratoses and basal cell carcinomas - differentiation by quantification of signal intensity and layer thickness. Previous studies have shown that actinic keratoses (AKs) and basal cell carcinomas (BCCs) can be diagnosed by optical coherence tomography (OCT) based on morphological characteristics. There is a lack of systematic studies that give standardized information on signal intensity and layer thickness of AKs and BCCs.The aim of this study

2016 Journal of the European Academy of Dermatology and Venereology

52. Actikerall™ (5-Fluorouracil 0.5% and Salicylic Acid 10%) Topical Solution for Patient-directed Treatment of Actinic Keratoses. (PubMed)

Actikerall™ (5-Fluorouracil 0.5% and Salicylic Acid 10%) Topical Solution for Patient-directed Treatment of Actinic Keratoses. Actinic keratosis (AK), a common cutaneous lesion with the potential to transform into squamous cell carcinoma, has traditionally been treated with ablative and/or surgical procedures. Recently, a topical formulation combining 0.5% 5-fluorouracil with 10% salicylic acid (5-FU-SA) was introduced in Europe under the trade name Actikerall™ for the treatment of grade I/II

2016 Skin therapy letter

53. Long-term Outcome of Low-concentration Hexyl-5-aminolaevulinate Daylight Photodynamic Therapy for Treatment of Actinic Keratoses. (PubMed)

Long-term Outcome of Low-concentration Hexyl-5-aminolaevulinate Daylight Photodynamic Therapy for Treatment of Actinic Keratoses. 27304514 2017 01 26 2017 05 05 1651-2057 97 1 2017 01 04 Acta dermato-venereologica Acta Derm. Venereol. Long-term Outcome of Low-concentration Hexyl-5-aminolaevulinate Daylight Photodynamic Therapy for Treatment of Actinic Keratoses. 120-121 10.2340/00015555-2484 Neittaanmäki-Perttu Noora N Department of Dermatology and Allergology, Helsinki University Central (...) Hospital, FIN-00029 Helsinki, Finland. noora.neittaanmaki@fimnet.fi. Karppinen Toni Tapani TT Tani Taneli T Snellman Erna E Grönroos Mari M eng Journal Article Sweden Acta Derm Venereol 0370310 0001-5555 0 Photosensitizing Agents 88755TAZ87 Aminolevulinic Acid G7H20TKI67 5-aminolevulinic acid hexyl ester IM Aged Aminolevulinic Acid analogs & derivatives therapeutic use Head Humans Keratosis, Actinic drug therapy Male Pain Measurement Photochemotherapy Photosensitizing Agents therapeutic use Treatment

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2016 Acta Dermato-Venereologica

54. Actinic Keratoses

Actinic Keratoses Actinic Keratoses Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Actinic Keratoses Actinic Keratoses Aka: Actinic (...) Keratoses , Actinic Keratosis From Related Chapters II. Epidemiology Most common premalignant skin lesion Responsible for 60% of involving the skin : White skin (increases with age) Age 20-29: 10% Age 80-89: 75% III. Pathophysiology Superficial keratotic tumor Previously considered distinct premalignant changes Now thought to be very early s IV. Risk Factors Fair-skinned, blue-eyed persons Living in sunny climate Cummulative extensive Older persons V. Symptoms Typically asymptomatic May be pruritic

2018 FP Notebook

55. Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil

Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02938715 Recruitment Status : Completed First

2016 Clinical Trials

56. Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. (PubMed)

Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. Ingenol mebutate (IngMeb) is approved for treatment of actinic keratoses (AK) and may cause unpredictable local skin responses (LSR).We sought to investigate whether IngMeb-induced LSR, pain, and pruritus could be alleviated with a topical glucocorticoid and, further, to assess efficacy, cosmetic outcome, and patient

2016 Journal of the American Academy of Dermatology

57. Artificial White Light vs Daylight Photodynamic Therapy for Actinic Keratoses: A Randomized Clinical Trial. (PubMed)

Artificial White Light vs Daylight Photodynamic Therapy for Actinic Keratoses: A Randomized Clinical Trial. Daylight photodynamic therapy using topical methyl 5-aminolevulinic acid (MAL) for actinic keratoses (AKs) is as effective as conventional photodynamic therapy but has the advantage of being almost pain free. Daylight photodynamic therapy, however, requires dry and warm weather conditions.To establish if topical MAL photodynamic therapy using a white light light-emitting diode (LED) lamp

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2016 JAMA dermatology

58. Randomized Vehicle-Controlled Study of Short Drug Incubation Aminolevulinic Acid Photodynamic Therapy for Actinic Keratoses of the Face or Scalp. (PubMed)

Randomized Vehicle-Controlled Study of Short Drug Incubation Aminolevulinic Acid Photodynamic Therapy for Actinic Keratoses of the Face or Scalp. Aminolevulinic acid photodynamic therapy (ALA-PDT) can be effective and well tolerated when applied over a broad area and for short drug incubation times.To evaluate the effect of short-incubation time and application method on the safety and efficacy of ALA-PDT versus vehicle (VEH-PDT) in the treatment of actinic keratoses (AKs) of the face

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2016 Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

59. Pulse photodynamic therapy reduces inflammation without compromising efficacy in the treatment of multiple mild actinic keratoses of the face and scalp - a randomized clinical trial. (PubMed)

Pulse photodynamic therapy reduces inflammation without compromising efficacy in the treatment of multiple mild actinic keratoses of the face and scalp - a randomized clinical trial. The main side-effects of photodynamic therapy (PDT) for actinic keratoses (AKs) are post-treatment erythema and oedema, and pain during illumination. Severe erythema after PDT enhances the down time associated with the treatment.To evaluate in a randomized intraindividual study whether pulse-PDT and corticosteroid

2016 The British journal of dermatology

60. A Randomized Split-Face Clinical Trial of Photodynamic Therapy with Methyl Aminolevulinate versus Ingenol Mebutate Gel for the Treatment of Multiple Actinic Keratoses of the Face and Scalp. (PubMed)

A Randomized Split-Face Clinical Trial of Photodynamic Therapy with Methyl Aminolevulinate versus Ingenol Mebutate Gel for the Treatment of Multiple Actinic Keratoses of the Face and Scalp. Photodynamic therapy with methyl aminolevulinate (MAL-PDT) and ingenol mebutate gel (IMB) are approved therapeutic options for multiple actinic keratoses (AKs).The aim of this intraindividual, split-face, randomized clinical trial was to compare treatment outcomes of MAL-PDT and IMB.Two symmetrical

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2016 Dermatology

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