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81. Specific cognitive-neurophysiological processes predict impulsivity in the childhood attention-deficit/hyperactivity disorder combined subtype. (Full text)

Specific cognitive-neurophysiological processes predict impulsivity in the childhood attention-deficit/hyperactivity disorder combined subtype. Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neuropsychiatric disorders in childhood. Besides inattention and hyperactivity, impulsivity is the third core symptom leading to diverse and serious problems. However, the neuronal mechanisms underlying impulsivity in ADHD are still not fully understood. This is all the more (...) subprocesses from perceptual gating to attentional selection, resource allocation and response selection processes are altered in this patient group. Perceptual gating, stimulus-driven attention selection and resource allocation processes were more pronounced in ADHD-C, are related to activation differences in parieto-occipital networks and suggest attentional filtering deficits. However, only response selection processes, associated with medial prefrontal networks, predicted impulsive errors in ADHD

2016 Psychological Medicine PubMed abstract

82. Diagnostic accuracy of a brief screening tool for attention deficit hyperactivity disorder in UK prison inmates. (Full text)

Diagnostic accuracy of a brief screening tool for attention deficit hyperactivity disorder in UK prison inmates. Attention deficit hyperactivity disorder (ADHD) is overrepresented in prison, making it imperative to identify a screening tool that can be quickly applied to efficiently detect the disorder. We explored the discrimination ability of a widely used ADHD screen, the Barkley Adult ADHD Rating Scale (BAARS-IV), against a clinical diagnostic interview. A brief version of the screen (...) accuracy. The brief screening instrument has great potential to be used as an accurate and resource-effective tool to screen young people and adults for likely ADHD in the criminal justice system.

2016 Psychological Medicine PubMed abstract

83. Neuroelectric and Behavioral Effects of Acute Exercise on Task Switching in Children with Attention-Deficit/Hyperactivity Disorder (Full text)

Neuroelectric and Behavioral Effects of Acute Exercise on Task Switching in Children with Attention-Deficit/Hyperactivity Disorder The main purpose of this two-part study was to examine the effects of acute, moderate intensity exercise on task switching in children with attention-deficit/hyperactivity disorder (ADHD). In Study 1, we compared the task switching performance of children with and without ADHD. Twenty children with ADHD and 20 matched controls performed the task switching paradigm (...) , in which the behavioral indices and P3 component of event-related potentials elicited by task-switching were assessed simultaneously. The amplitude and latency of P3 reflected the amount of attention resource allocated to task-relevant stimulus in the environment and the efficiency of stimulus detection and evaluation, respectively. The task switching included two conditions; the pure condition required participants to perform the task on the same rule (e.g., AAAA or BBBB) whereas the mixed condition

2016 Frontiers in psychology PubMed abstract

84. A Cost-Utility Analysis of Lisdexamfetamine Versus Atomoxetine in the Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder and Inadequate Response to Methylphenidate (Full text)

A Cost-Utility Analysis of Lisdexamfetamine Versus Atomoxetine in the Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder and Inadequate Response to Methylphenidate An economic analysis from the perspective of the UK National Health Service (NHS) evaluated the cost effectiveness of lisdexamfetamine dimesylate (LDX) compared with atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder who have had an inadequate response (...) identified via a systematic literature review. Healthcare resource use estimates were obtained via a survey of clinicians. Daily drug costs were derived from British National Formulary 2012 costs and mean doses reported in the trial. One-way and probabilistic sensitivity analyses (PSAs) were performed.The comparison of LDX with atomoxetine resulted in an estimate of an incremental cost-effectiveness ratio of £1802 per quality-adjusted life-year (QALY). The result was robust in a wide range of sensitivity

2016 CNS drugs PubMed abstract

85. Methylphenidate in Adults With Attention Deficit/Hyperactivity Disorder

Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Keywords provided by Hospital de Clinicas de Porto Alegre: ADHD Adults treatment Methylphenidate Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Methylphenidate (...) treatment outcomes in ADHD. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 600 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Methylphenidate in Adults With Attention Deficit/Hyperactivity Disorder Study Start Date : February 2002 Estimated Primary Completion Date : December 2032 Estimated Study Completion Date : December 2032 Resource links provided

2016 Clinical Trials

86. Cognitive Behavior Group Therapy in Adolescents With Attention Deficit Hyperactivity Disorder

. The intervention consists of 12 weekly cognitive behavioral therapy sessions addressing core difficulties and concerns of the adolescent population with ADHD. The investigators wish to determine the efficacy of group therapy in adolescents with ADHD who receive medical treatment but still have impairing ADHD symptoms. Condition or disease Intervention/treatment Phase Attention Deficit Disorder With Hyperactivity Behavioral: cognitive behavior group therapy Other: Treatment as usual Not Applicable Study Design (...) Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 96 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Official Title: Cognitive Behavior Group Therapy in Adolescents (14-18 Years) With Attention Deficit Hyperactivity Disorder (ADHD) Study Start Date : January 2017 Estimated Primary Completion Date : January 2020 Estimated Study Completion Date

2016 Clinical Trials

87. Attention Deficit Hyperactivity Disorder: Nutrition and Environment

and Environmental Conditions in Attention Deficit Hyperactivity Disorder Study Start Date : November 2016 Estimated Primary Completion Date : May 2017 Estimated Study Completion Date : June 2017 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Nutritional intervention Patients subject to nutritional education by CINUSA group protocol Behavioral: Nutritional education Nutritional education trough a personal online (...) nutritional consultant No Intervention: No intervention Patients not subject to nutritional education Outcome Measures Go to Primary Outcome Measures : Change in Conners [ Time Frame: At 3 and 6 months ] Conners conduct questionnaire: attention deficit and disruptive behavior disorders; hyperactivity; and combined type. Secondary Outcome Measures : Change in sleep [ Time Frame: At 3 and 6 months ] Markers related to sleep: adapted Short Form Health Survey-36 for sleep quality. Change in exercise markers

2016 Clinical Trials

88. The Effects of Working Memory Training in Children With Attention-Deficit/Hyperactivity Disorder

: Chang Gung Memorial Hospital Information provided by (Responsible Party): I-hsuan Shen, Chang Gung Memorial Hospital Study Details Study Description Go to Brief Summary: Previous studies indicated that children with attention-deficit/hyperactivity disorder (ADHD) often suffer from deficits in executive function, such as attentional control, inhibition, and working memory. One of these executive functions, working memory, plays a critical role in academic performance and classroom behavior. Working (...) Party: I-hsuan Shen, Associated professor, Chang Gung Memorial Hospital ClinicalTrials.gov Identifier: Other Study ID Numbers: 104-5308A3 First Posted: November 9, 2016 Last Update Posted: October 26, 2017 Last Verified: October 2017 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior

2016 Clinical Trials

89. Rhodiola Rosea in Adults With Attention Deficit/Hyperactivity Disorder

Numbers: 150425 First Posted: April 13, 2016 Last Update Posted: August 22, 2017 Last Verified: August 2017 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Keywords provided by Hospital de Clinicas de Porto Alegre: ADHD Adults Treatment Rhodiola rosea Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental (...) : Hospital de Clinicas de Porto Alegre Information provided by (Responsible Party): Hospital de Clinicas de Porto Alegre Study Details Study Description Go to Brief Summary: This study evaluates the use of Rhodiola rosea in the treatment of Attention Deficit/Hyperactivity Disorder (ADHD) in adults. Half of participants will receive Rhodiola rosea, while the other half will receive placebo. Condition or disease Intervention/treatment Phase Attention Deficit/Hyperactivity Disorder Drug: Rhodiola Drug

2016 Clinical Trials

90. The Effect of Methylphenidate on Primary Enuresis in Children With Attention Deficit Hyperactivity Disorder

Urinary Incontinence Nocturnal Enuresis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Urination Disorders Urologic Diseases Behavioral Symptoms Elimination Disorders Lower Urinary Tract Symptoms Urological Manifestations Methylphenidate Central Nervous System Stimulants Physiological Effects of Drugs Dopamine Uptake Inhibitors Neurotransmitter Uptake (...) The Effect of Methylphenidate on Primary Enuresis in Children With Attention Deficit Hyperactivity Disorder The Effect of Methylphenidate on Primary Enuresis in Children With Attention Deficit Hyperactivity Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2016 Clinical Trials

91. Group-based Cognitive-behavioral Therapy for Adults With Attention-deficit/Hyperactivity Disorder Inattentive-type

, and 4. The CBT for ADHD-I protocol reduces core symptoms of ADHD-I as well as symptoms of stress, depression, and anxiety, and improves quality of life. Condition or disease Intervention/treatment Phase Attention Deficit Disorder With Hyperactivity Behavioral: Cognitive-behavioral therapy Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 40 participants Intervention Model: Single Group Assignment Primary Purpose (...) : Treatment Official Title: Group-based Cognitive-behavioral Therapy for Adults With Attention-deficit/Hyperactivity Disorder Inattentive-type: a Pilot Study Study Start Date : August 2016 Actual Primary Completion Date : June 2017 Actual Study Completion Date : June 2017 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Cognitive-behavioral therapy Behavioral: Cognitive-behavioral therapy Outcome Measures Go

2016 Clinical Trials

92. Early Interventions in Children With Attention Deficit/Hyperactivity Disorder

: No Keywords provided by Guilherme Vanoni Polanczyk, University of Sao Paulo: Parental training Preschool age Attention Deficit/Hyperactivity Disorder (ADHD) Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Methylphenidate Central (...) to neurobiological measures. Implications: This study proposes an innovative and relevant analysis, which will enable the field to advance the knowledge of biological mechanisms related to ADHD and to treatment response. Also, the study will expand the evidence to guide early prevention strategies and early intervention. Condition or disease Intervention/treatment Phase Attention Deficit Disorder With Hyperactivity Preschool Child Drug: Methylphenidate Behavioral: Parental training Other: Psychoeducational

2016 Clinical Trials

93. Caregiver Treatment Preferences for Children with a New Versus Existing Attention-Deficit/Hyperactivity Disorder Diagnosis. (Full text)

Caregiver Treatment Preferences for Children with a New Versus Existing Attention-Deficit/Hyperactivity Disorder Diagnosis. Parental experiences with managing their child's attention-deficit/hyperactivity disorder (ADHD) can influence priorities for treatment. This study aimed to identify the ADHD management options caregivers most prefer and to determine if preferences differ by time since initial ADHD diagnosis.Primary caregivers (n = 184) of a child aged 4-14 years old in care for ADHD were (...) . A conditional logit model using effect-coded variables was used to estimate preference weights stratified by time since ADHD diagnosis.Participants were primarily the mother (84%) and had a college or postgraduate education (76%) with 75% of the children on stimulant medications. One-on-one caregiver behavior training, medication use seven days a week, therapy in a clinic, and an individualized education program were most preferred for managing ADHD. Aside from caregiver training and monthly out-of-pocket

2016 Journal of Child and Adolescent Psychopharmacology PubMed abstract

94. A Randomized Controlled Trial of a School-Implemented School-Home Intervention for Attention-Deficit/Hyperactivity Disorder Symptoms and Impairment. (Abstract)

A Randomized Controlled Trial of a School-Implemented School-Home Intervention for Attention-Deficit/Hyperactivity Disorder Symptoms and Impairment. This study evaluated the efficacy of a novel psychosocial intervention (Collaborative Life Skills [CLS]) for primary-school students with attention-deficit/hyperactivity disorder (ADHD) symptoms. CLS is a 12-week program consisting of integrated school, parent, and student treatments delivered by school-based mental health providers. Using (...) practices for decreasing ADHD and oppositional defiant disorder symptoms and improving key areas of functional impairment. They further suggest that existing school-based mental health resources can be redeployed from non-empirically supported practices to those with documented efficacy. This model holds promise for improving access to efficient evidence-based treatment for inattentive and disruptive behavior beyond the clinic setting. Clinical Trial Registration Information-Study of the Collaborative

2016 Journal of the American Academy of Child and Adolescent Psychiatry Controlled trial quality: uncertain

95. Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder

," the clinician asked questions 3-5. Active suicidal ideation included any participant who answered "yes" to questions 2-5. If the answers to ideation questions 1 and 2 were "No," then the clinician proceeded to 5 (yes/no) questions that addressed suicidal behavior, which was categorized as actual attempt, interrupted attempt, aborted attempt, preparatory acts or behaviors, and completed suicide. Secondary Outcome Measures : Change From Baseline in Attention Deficit/Hyperactivity Disorder Rating Scale (ADHD (...) -211 First Posted: March 30, 2015 Results First Posted: October 25, 2018 Last Update Posted: October 25, 2018 Last Verified: November 2017 Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms

2015 Clinical Trials

96. Safety and Tolerability Study of SPD489 in Preschool Children Aged 4-5 Years, Diagnosed With Attention-deficit/Hyperactivity Disorder

Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Lisdexamfetamine Dimesylate Central Nervous System Stimulants Physiological Effects of Drugs Dopamine Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Dopamine Agents (...) Recruitment Status : Active, not recruiting First Posted : June 9, 2015 Last Update Posted : January 16, 2019 Sponsor: Shire Information provided by (Responsible Party): Shire Study Details Study Description Go to Brief Summary: To evaluate the long-term safety of SPD489 administered as a daily morning dose (5, 10, 15, 20, and 30 mg/day) in preschool children diagnosed with Attention-deficit/Hyperactivity Disorder (ADHD). Participants will be enrolled into this study from antecedent study SPD489-211

2015 Clinical Trials

97. Brain Training in Children With/At-risk for Attention-Deficit/Hyperactivity Disorder and Executive Function Impairment

With or At-risk for Attention-Deficit/Hyperactivity Disorder (ADHD) and Executive Function (EF) Impairment Study Start Date : October 2015 Estimated Primary Completion Date : December 2018 Estimated Study Completion Date : December 2019 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Brain Training (Active) The children in this arm receive one type of "Brain Training" with online computer games that actively (...) : Other Study ID Numbers: 30874-2 First Posted: October 27, 2015 Last Update Posted: August 21, 2018 Last Verified: August 2018 Keywords provided by Irene M. Loe, Stanford University: Attention Deficit Hyperactivity Disorder; executive function; preschool Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders

2015 Clinical Trials

98. Attention-deficit/Hyperactivity Disorder Translational Center for Identifying Biomarkers

Update Posted: December 7, 2015 Last Verified: December 2015 Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Methylphenidate Atomoxetine Hydrochloride Central Nervous System Stimulants Physiological Effects of Drugs Dopamine (...) was: Recruiting First Posted : December 7, 2015 Last Update Posted : December 7, 2015 Sponsor: Seoul National University Childrens Hospital Information provided by (Responsible Party): Booog Nyung Kim, Seoul National University Childrens Hospital Study Details Study Description Go to Brief Summary: The purpose of this study was to identify genetic, brain morphologic, and environmental biomarkers that contribute to the pathophysiology of attention-deficit/hyperactivity disorder (ADHD). Condition or disease

2015 Clinical Trials

99. Effects of a Probiotic Supplement on Symptoms of Attention Deficit Hyperactivity Disorder and Anxiety in Children

ClinicalTrials.gov Identifier: Other Study ID Numbers: APB-C1 First Posted: September 10, 2015 Last Update Posted: September 10, 2015 Last Verified: September 2015 Keywords provided by Acadia University: probiotic ADHD anxiety digestive health children attention deficit gut brain axis nutritional supplement microbiome Additional relevant MeSH terms: Layout table for MeSH terms Anxiety Disorders Attention Deficit Disorder with Hyperactivity Hyperkinesis Mental Disorders Attention Deficit and Disruptive Behavior (...) and anxiety in children. The main goal is to determine if probiotics might be useful as a treatment for anxiety and ADHD symptoms in children. A second goal is to examine the effects of probiotics on saliva cortisol levels. Finally, the investigators are also interested in the effects of the probiotics on children's digestive health. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Anxiety Dietary Supplement: L. helveticus R0052 and B. longum R0175 Other: Placebo

2015 Clinical Trials

100. Cognitive Behavioral Therapy for Adolescents With Attention-Deficit / Hyperactivity Disorder

adolescents with ADHD, it can be made widely available to these adolescents in the community. This would help them improve their academic, social, and emotional functioning and ultimately their long term outcomes. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Behavioral: Cognitive Behavioural & Skills Training Behavioral: Supportive Group Therapy Other: Treatment as Usual - community resources Drug: Methylphenidate or amphetamine product Phase 4 Detailed (...) , 2018 Last Verified: July 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Plan Description: There is no plan to make individual data available. Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms

2015 Clinical Trials

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