How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

131 results for

ABCD2 Score

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21. HINTS Outperforms ABCD2 to Screen for Stroke in Acute Continuous Vertigo and Dizziness. (Abstract)

, and new gait unsteadiness) at a single academic center. All underwent neurootologic examination, neuroimaging (97.4% by magnetic resonance imaging [MRI]), and follow-up. ABCD2 risk scores (0-7 points), using the recommended cutoff of ≥4 for stroke, were compared to a three-component eye movement battery (HINTS). Sensitivity, specificity, and positive and negative likelihood ratios (LR+, LR-) were assessed for stroke and other central causes, and the results were stratified by age. False-negative (...) HINTS Outperforms ABCD2 to Screen for Stroke in Acute Continuous Vertigo and Dizziness. Dizziness and vertigo account for about 4 million emergency department (ED) visits annually in the United States, and some 160,000 to 240,000 (4% to 6%) have cerebrovascular causes. Stroke diagnosis in ED patients with vertigo/dizziness is challenging because the majority have no obvious focal neurologic signs at initial presentation. The authors sought to compare the accuracy of two previously published

2013 Academic Emergency Medicine

22. Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA study Full Text available with Trip Pro

Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA study Transient ischemic attack (TIA) etiologic data and the ABCD(2) score may improve early stroke risk prediction, but studies are required in population-based cohorts. We investigated the external validity of the ABCD(2) score, carotid stenosis, and atrial fibrillation for prediction of early recurrent stroke after TIA.Patients (...) , 9.7% to 29.7%) with severe stenosis/occlusion (hazard ratio=3.3; 95% CI, 1.5 to 7.4, P=0.002). In confirmed TIA cases (n=443), the ABCD(2) score performed no better than chance for prediction of 90-day stroke (c-statistic=0.55; 95% CI, 0.45 to 0.64), largely related to the 24.2% (8/33) of patients who experienced a recurrence and had low ABCD(2) scores (0-3). However, in nonspecialist-suspected TIA cases (n=700), the predictive utility improved for stroke at 28 (c-statistic=0.61; 95% CI, 0.50

2010 EvidenceUpdates

23. ABCD2 score predicts severity rather than risk of early recurrent events after transient ischemic attack Full Text available with Trip Pro

ABCD2 score predicts severity rather than risk of early recurrent events after transient ischemic attack The ABCD(2) score predicts the early risk of stroke after transient ischemic attack (TIA). However, data on the severity of recurrent events would also be useful. Do patients with high scores also have more severe early recurrent strokes, perhaps further justifying hospital admission? Do patients with low scores have a low early risk of recurrent TIA as well as recurrent stroke?We completed (...) a prospective, population-based study in Oxfordshire, England, of 500 consecutive patients presenting with TIA from April 1, 2002, by using multiple methods of case ascertainment (Oxford Vascular Study). Recurrent TIA, minor stroke, and major stroke (National Institutes of Health Stroke Scale score >3 at the time of first assessment) were identified by face-to-face follow-up. Predictive value was expressed as the area under the receiver operating characteristic curve.Of 500 patients with TIA, 55 had

2010 EvidenceUpdates

24. Multicenter external validation of the ABCD2 score in triaging TIA patients (Abstract)

Multicenter external validation of the ABCD2 score in triaging TIA patients A simple clinical score (ABCD(2) score) has been introduced to triage TIA patients with a high early risk of stroke. External validation studies have yielded inconsistent results regarding the predictive ability of the ABCD(2) score. We aimed to prospectively validate the former score in a multicenter case series study.We prospectively calculated the ABCD(2) score (age [> or = 60 years: 1 point]; blood pressure (...) % CI 10%-22%). The ABCD(2) score accurately discriminated between TIA patients with high 7-day (c statistic 0.72, 95% CI 0.57-0.88) and 90-day (c statistic 0.75, 95% CI 0.65-0.86) risks of stroke. The 90-day risk of stroke was 7-fold higher in patients with an ABCD(2) score >3 points (28%, 95% CI 18%-38%) than in patients with an ABCD(2) score < or = 3 points (4%, 95% CI 0%-9%). After adjustment for stroke risk factors, race, history of previous TIA, medication use before the index TIA

2010 EvidenceUpdates

25. A multicenter evaluation of the ABCD2 score`s accuracy for predicting early ischemic stroke in admitted patients with transient ischemic attack (Abstract)

A multicenter evaluation of the ABCD2 score`s accuracy for predicting early ischemic stroke in admitted patients with transient ischemic attack We evaluate, in admitted patients with transient ischemic attack, the accuracy of the ABCD(2) (age [A], blood pressure [B], clinical features [weakness/speech disturbance] [C], transient ischemic attack duration [D], and diabetes history [D]) score in predicting ischemic stroke within 7 days.At 16 North Carolina hospitals, we enrolled a prospective (...) , nonconsecutive sample of admitted patients with transient ischemic attack and with no stroke history, presenting within 24 hours of transient ischemic attack symptom onset. We conducted a medical record review to determine ischemic stroke outcomes within 7 days. According to a modified Rankin Scale Score, strokes were classified as disabling (>2) or nondisabling (< or =2).During a 35-month period, we enrolled 1,667 patients, of whom 373 (23%) received a diagnosis of an ischemic stroke within 7 days. Eighteen

2010 EvidenceUpdates

26. Addition of brain infarction to the ABCD2 Score (ABCD2I): a collaborative analysis of unpublished data on 4574 patients Full Text available with Trip Pro

Addition of brain infarction to the ABCD2 Score (ABCD2I): a collaborative analysis of unpublished data on 4574 patients The ABCD system was developed to predict early stroke risk after transient ischemic attack. Incorporation of brain imaging findings has been suggested, but reports have used inconsistent methods and been underpowered. We therefore performed an international, multicenter collaborative study of the prognostic performance of the ABCD(2) score and brain infarction on imaging (...) to determine the optimal weighting of infarction in the score (ABCD(2)I).Twelve centers provided unpublished data on ABCD(2) scores, presence of brain infarction on either diffusion-weighted imaging or CT, and follow-up in cohorts of patients with transient ischemic attack diagnosed by World Health Organization criteria. Optimal weighting of infarction in the ABCD(2)I score was determined using area under the receiver operating characteristic curve analyses and random effects meta-analysis.Among 4574

2010 EvidenceUpdates

27. Diagnosis of TIA (DOT) score - design and validation of a new clinical diagnostic tool for transient ischaemic attack. Full Text available with Trip Pro

Diagnosis of TIA (DOT) score - design and validation of a new clinical diagnostic tool for transient ischaemic attack. The diagnosis of Transient Ischaemic Attack (TIA) can be difficult and 50-60% of patients seen in TIA clinics turn out to be mimics. Many of these mimics have high ABCD2 scores and fill urgent TIA clinic slots inappropriately. A TIA diagnostic tool may help non-specialists make the diagnosis with greater accuracy and improve TIA clinic triage. The only available diagnostic (...) score (Dawson et al) is limited in scope and not widely used. The Diagnosis of TIA (DOT) Score is a new and internally validated web and mobile app based diagnostic tool which encompasses both brain and retinal TIA.The score was derived retrospectively from a single centre TIA clinic database using stepwise logistic regression by backwards elimination to find the best model. An optimum cutpoint was obtained for the score. The derivation and validation cohorts were separate samples drawn from

2016 BMC Neurology

28. Clinical predictive value of the ABCD2 score for early risk of stroke in patients who have had transient ischaemic attack and who present to an Australian tertiary hospital. (Abstract)

Clinical predictive value of the ABCD2 score for early risk of stroke in patients who have had transient ischaemic attack and who present to an Australian tertiary hospital. To determine the predictive value of the ABCD(2) score for early risk of stroke in Australian patients who have had transient ischaemic attack (TIA).Cohort study of 512 consecutive patients with suspected TIA referred by the emergency department to the acute stroke unit (in accordance with the TIA pathway) of an urban (...) tertiary hospital in Melbourne, Victoria, between 1 June 2004 and 30 November 2007.Overall accuracy, estimated by the area under the curve (AUC) of receiver operating characteristic plots (of true positive rate v false positive rate), and sensitivity, specificity, predictive values and likelihood ratios at prespecified cut-off ABCD(2) scores for stroke within 2, 7 and 90 days.24 patients were excluded because their symptoms lasted more than 24 hours. All included patients were reviewed by a stroke

2011 Medical Journal of Australia

29. Changes in Intracortical Excitability After Transient Ischemic Attack Are Associated With ABCD2 Score. Full Text available with Trip Pro

Changes in Intracortical Excitability After Transient Ischemic Attack Are Associated With ABCD2 Score. A transient ischemic attack (TIA) is a brief ischemic episode characterized by rapid clinical resolution and not associated with permanent cerebral infarction. Whether changes in intracortical excitability persist and are related to clinical predictors of stroke risk after TIA remains unknown.Participants were individuals with clinically resolved motor TIA with no structural lesions (...) and healthy age-matched control participants. Single and paired-pulse transcranial magnetic stimulation was used to measure intracortical excitability. Recruitment curves for percent inhibition and facilitation were used to derive excitability thresholds. Correlations between threshold asymmetries and ABCD(2) score were performed.Results showed a significant 3-way interaction with reduced inhibition and enhanced facilitation in the affected compared with unaffected hemisphere after TIA. No significant

2011 Stroke

30. Patients With Transient Ischemic Attack With ABCD2 <4 Can Have Similar 90-Day Stroke Risk as Patients With Transient Ischemic Attack With ABCD2 >=4. Full Text available with Trip Pro

Patients With Transient Ischemic Attack With ABCD2 <4 Can Have Similar 90-Day Stroke Risk as Patients With Transient Ischemic Attack With ABCD2 >=4. It is unclear whether patients with transient ischemic attack with an ABCD(2) score <4 can be safely evaluated within the following week as recommended by some national guidelines rather than in emergency.A total of 1679 patients in the SOS-TIA prospective cohort had a definite or possible transient ischemic attack and had complete information (...) on ABCD(2) score components. They were evaluated and treated as soon as possible in a transient ischemic attack clinic with round-the-clock access, 87% of them within 24 hours of the first call to medical attention. Criteria for emergency treatment were internal carotid or intracranial artery stenosis ≥50% or major cardiac source of embolism.Primary end point was stroke at 90 days. The 90-day stroke rate (number of events/number of patients) was 3.4% (24/701) in patients with ABCD(2) score ≥4, 3.9% (7

2011 Stroke

31. Early diffusion weighted MRI as a negative predictor for disabling stroke after ABCD2 score risk categorization in transient ischemic attack patients Full Text available with Trip Pro

Early diffusion weighted MRI as a negative predictor for disabling stroke after ABCD2 score risk categorization in transient ischemic attack patients The prognostic value early diffusion-weighted magnetic resonance imaging (DWMRI) adds in the setting of transient ischemic attack (TIA), after risk stratification by a clinical score, is unclear. The purpose of this study is to evaluate, after ABCD2 score risk categorization in admitted TIA patients, whether negative DWMRI performed within 24 (...) hours of symptom onset improves on the identification of patients at low risk for experiencing a disabling stroke within 90 days.At 15 North Carolina hospitals, we enrolled a prospective nonconsecutive sample of admitted TIA patients. We excluded patients not undergoing a DWMRI within 24 hours of admission and patients for whom a dichotomized (< or = or >3) ABCD2 score could not be calculated. We conducted a medical record review to determine disabling ischemic stroke outcomes within 90 days.Over 35

2009 EvidenceUpdates

32. Does ABCD2 score below 4 allow more time to evaluate patients with a transient ischemic attack? Full Text available with Trip Pro

Does ABCD2 score below 4 allow more time to evaluate patients with a transient ischemic attack? The National Institute for Clinical Excellence (NICE) recommends that patients with a transient ischemic attack and ABCD(2) score > or =4 and those with >2 transient ischemic attacks within 1 week be admitted for urgent complete etiologic evaluation within 24 hours and that those with an ABCD(2) score <4 be evaluated less urgently within 1 week.Using data from 1176 patients with a definite (...) or possible transient ischemic attack or minor stroke included in the SOS-TIA registry (January 2003 to June 2007), we studied the usefulness of the conventional ABCD(2) score cutoff as well as the NICE criteria for urgent admission to a stroke unit defined as presence of symptomatic internal carotid artery stenosis > or =50%, symptomatic intracranial artery stenosis > or =50%, or major cardiac source of embolism.Among 697 patients with an ABCD(2) score <4, 20% required immediate consideration

2009 EvidenceUpdates

33. Validation and refinement of the ABCD2 score: a population-based analysis Full Text available with Trip Pro

Validation and refinement of the ABCD2 score: a population-based analysis Transient ischemic attacks are a frequent diagnosis in the emergency department setting, yet expert opinion as to the proper follow-up and need for hospitalization differs widely. Recently, an effort has been made to risk-stratify patients presenting with transient ischemic attacks through scoring systems such as the ABCD and ABCD2 scales. The aim of our study was to independently validate these scores using a population (...) -based cohort.Using the data from the Rochester Stroke and Transient Ischemic Attack Registry and resources of the Rochester Epidemiology Project, medical records of all residents of Rochester, Minn, with a diagnosis of incident transient ischemic attack from 1985 through 1994 were examined (N=284). Patients were scored on the ABCD and ABCD2 scales and new scores were created by adding hyperglycemia and a history of hypertension. The end points of stroke and death were collected previously and were

2009 EvidenceUpdates

34. Prognostic value of the ABCD2 score beyond short-term follow-up after transient ischemic attack (TIA)--a cohort study. Full Text available with Trip Pro

Prognostic value of the ABCD2 score beyond short-term follow-up after transient ischemic attack (TIA)--a cohort study. Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA. We assessed the value of this score to predict the vascular outcome after TIA during medium- to long-term follow-up.The ABCD2 score of 176 TIA patients consecutively admitted to the Stroke Unit was retrospectively (...) for the combined endpoint of cerebral ischemic events, cardiac ischemic events and death of vascular or unknown cause.Fifty-five patients (32.0%) had an ABCD2 score < or = 3, 80 patients (46.5%) had an ABCD2 score of 4-5 points and 37 patients (21.5%) had an ABCD2 score of 6-7 points. Follow-up data were available in 173 (98.3%) patients. Twenty-two patients (13.8%) experienced an ischemic stroke or TIA; 5 (3.0%) a myocardial infarction or acute coronary syndrome; 10 (5.7%) died of vascular or unknown cause

2010 BMC Neurology

35. Validation of the ABCD2 Score to Identify the Patients With High Risk of Late Stroke After a Transient Ischemic Attack or Minor Ischemic Stroke. Full Text available with Trip Pro

Validation of the ABCD2 Score to Identify the Patients With High Risk of Late Stroke After a Transient Ischemic Attack or Minor Ischemic Stroke. The ABCD(2) score is able to predict the short-term risk of stroke after a transient ischemic attack/minor stroke. We aimed to explore its predictive value for long-term recurrent stroke.Consecutive patients with a transient ischemic attack/minor stroke, hospitalized during a 2-year period, were followed up to document any further stroke and death (...) stratified by a 7-point ABCD(2) score. Result- A total of 490 patients were followed for an average of 40.5 months (SD, 10.7 months). Further stroke were identified in 76 (15.5%) patients and 62 (12.7%) patients died during follow-up. Multivariate Cox regression analysis showed that an ABCD(2) score >4 was found to be an independent risk factor for further stroke (hazard ratio, 2.27; 95% CI, 1.36 to 3.80) and for death (hazard ratio, 1.68; 95% CI, 0.99 to 2.85).In addition to predicting short-term stroke

2010 Stroke

36. PAW17 Recurrent transient ischaemic attack, capsular warning syndrome, ABCD2 score and early risk of stroke: a population-based study. (Abstract)

PAW17 Recurrent transient ischaemic attack, capsular warning syndrome, ABCD2 score and early risk of stroke: a population-based study.

2010 Neurosurgery and Psychiatry

38. Stroke and transient ischaemic attack in over 16s: diagnosis and initial management

assessment and investigation, to be seen within 24 hours of onset of symptoms. [2019] [2019] 1.1.6 Do not use scoring systems, such as ABCD2, to assess risk of subsequent stroke or to inform urgency of referral for people who have had a suspected or confirmed TIA. [2019] [2019] Stroke and transient ischaemic attack in over 16s: diagnosis and initial management (NG128) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 (...) transient ischaemic attack Recommendations 1.1.5 to 1.1.7 Stroke and transient ischaemic attack in over 16s: diagnosis and initial management (NG128) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 22 of 38Wh Why the committee made the recommendations y the committee made the recommendations Evidence showed that risk prediction scores (ABCD2 and ABCD3) used in isolation are poor at discriminating low and high risk

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

39. Dual vs single antiplatelet therapy Full Text available with Trip Pro

neurological deficit 0 42 0 7 A score of 4 or more on the ABCD2 scale, which estimates the risk of recurrent stroke after a TIA We recommend dual antiplatelet therapy over single agent therapy. Start as soon as possible after index event. More details Strong All or nearly all informed people would likely want this option. Benefits outweigh harms for almost everyone. Weak Most people would likely want this option. Benefits outweigh harms for the majority, but not for everyone. Weak Most people would likely (...) : The ABCD2 score and NIHSS score are typically used to help assess the severity of a transient ischaemic attack or stroke and can help to guide future care. Around 1 in 10 people go on to have a stroke after high risk transient ischaemic attack ( ). The chance of a further stroke soon after minor stroke is less clear but is likely to be around 10-12% range. Box 2 Assessment of severity of transient ischaemic attack and minor stroke and subsequent risk of stroke Transient ischaemic attack Severity

2018 BMJ Rapid Recommendations

40. Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update

for nondiagnostic studies 17 Table 5. Definition of strength of evidence grades 19 Table 6. Thromboembolic events by CHADS2 score and on antiplatelet and/or anticoagulant therapy 27 Table 7. Thromboembolic events by CHADS2 score and who are off therapy 29 Table 8. Thromboembolic events by CHADS2 score and for whom underlying anticoagulant/antiplatelet therapy is mixed or unclear 30 Table 9. Thromboembolic events by CHA2DS2-VASc score and who are on antiplatelet and/or anticoagulant therapy 32 Table 10 (...) . Thromboembolic events by CHA2DS2-VASc score and who are off therapy 35 Table 11. Thromboembolic events by CHA2DS2-VASc score and for whom underlying anticoagulant/antiplatelet therapy is mixed or unclear 38 Table 12. Thromboembolic events by Framingham risk score and who are on antiplatelet and/or anticoagulant therapy 39 Table 13. Thromboembolic events by Framingham risk score and for whom underlying anticoagulant/antiplatelet therapy is mixed or unclear 39 Table 14. Thromboembolic events by Framingham risk

2018 Effective Health Care Program (AHRQ)

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>