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(orthopedic) from:2005 to:2010)

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81. Fixation of subtrochanteric extending/derotational femoral osteotomies with the Locking Compression Plate in ambulatory neuro-orthopaedic patients Full Text available with Trip Pro

Fixation of subtrochanteric extending/derotational femoral osteotomies with the Locking Compression Plate in ambulatory neuro-orthopaedic patients Patients with neuro-orthopaedic disorders often develop hip flexion contractures or rotational hip deformities. Increasing deformities impair the already diminished walking abilities and proximal femoral osteotomies are often performed to maintain/improve walking abilities. Fixation of the osteotomies with condylar plates has been successfully used (...) /4.5 Locking Compression Plate (LCP; Synthes(®)) and postoperative full weight bearing in ambulatory neuro-orthopaedic patients.Fifteen ambulatory neuro-orthopaedic patients (12 cerebral palsy [CP], 1 trisomy 21, 2 hemiparesis) with a mean age of 13.7 years (range 7-22) with hip flexion contractures and/or rotational deformities underwent subtrochanteric (n = 26) osteotomy between July 2004 and October 2007. All patients were allowed to bear their full weight postoperatively. We investigated

2010 Journal of children's orthopaedics

82. A novel route for processing cobalt–chromium–molybdenum orthopaedic alloys Full Text available with Trip Pro

A novel route for processing cobalt–chromium–molybdenum orthopaedic alloys Spark plasma sintering has been used for the first time to prepare the ASTM F75 cobalt-chromium-molybdenum (Co-Cr-Mo) orthopaedic alloy composition using nanopowders. In the preliminary work presented in this report, the effect of processing variables on the structural features of the alloy (phases present, grain size and microstructure) has been investigated. Specimens of greater than 99.5 per cent theoretical

2010 Journal of the Royal Society Interface

83. Population pharmacokinetics of fondaparinux administered at prophylactic doses after major orthopaedic surgery in everyday practice. (Abstract)

Population pharmacokinetics of fondaparinux administered at prophylactic doses after major orthopaedic surgery in everyday practice. Fondaparinux is a synthetic antithrombotic agent with specific anti-factor Xa activity. A population pharmacokinetic model of fondaparinux, based on data obtained in patients included in phase II/III trials, has been described. However, the validity of this model in everyday practice needed to be confirmed. This study was a multicenter, prospective cohort study (...) in consecutive orthopaedic patients treated with 2.5 mg of fondaparinux. Anti-Xa activities were recorded in 809 patients. Population parameters and inter-individual variability were estimated using NONMEM VI software. A two-compartment model with first-order absorption best described fondaparinux pharmacokinetics. Covariates partly explaining inter-individual variability were body weight, age and creatinine clearance estimated by the simplified Modification of Diet in Renal Disease formula (MDRD). A body

2010 Thrombosis and haemostasis

84. Asia-Pacific Thrombosis Advisory Board consensus paper on prevention of venous thromboembolism after major orthopaedic surgery. Full Text available with Trip Pro

Asia-Pacific Thrombosis Advisory Board consensus paper on prevention of venous thromboembolism after major orthopaedic surgery. The incidence of postoperative venous thromboembolism (VTE) in Asian populations is generally thought to be lower than in Western populations, and the use of thromboprophylaxis after surgery is not routine. This paper is authored by the Asia-Pacific Thrombosis Advisory Board. To provide guidance on the most effective postoperative thromboprophylaxis management

2010 Thrombosis and haemostasis

85. Troponin I and NT-proBNP (N-terminal pro-brain natriuretic peptide) do not predict 6-month mortality in frail older patients undergoing orthopedic surgery. (Abstract)

Troponin I and NT-proBNP (N-terminal pro-brain natriuretic peptide) do not predict 6-month mortality in frail older patients undergoing orthopedic surgery. To determine if troponin I and NT-proBNP were predictors of 6-month mortality after emergency orthopedic-geriatric surgery in a frail population.Prospective observational study.Orthopedic-geriatric unit of a metropolitan hospital in Australia.A total of 383 patients were screened; 44 were eligible for this study of which 33 patients (...) or cardiac events in an older frailer population of patients undergoing orthopedic surgery. These patients sustained substantial cardiac morbidity and mortality at 6 months after surgery. The control of symptoms, rather than prolongation of life with cardiological intervention, may be more appropriate for this patient group.2010. Published by Elsevier Inc. All rights reserved.

2010 Journal of the American Medical Directors Association

86. Ketamine/midazolam versus etomidate/fentanyl: procedural sedation for pediatric orthopedic reductions. (Abstract)

Ketamine/midazolam versus etomidate/fentanyl: procedural sedation for pediatric orthopedic reductions. Orthopedic reductions are commonly performed procedures requiring sedation in the pediatric emergency department (PED). Ketamine is a widely used agent for pediatric procedural sedation, but its use may present difficulties in select populations, such as those with psychiatric diagnoses. In such a case, alternative agents that are safe and effective are needed. Etomidate is a commonly used (...) induction agent for rapid-sequence intubation in the PED. Several retrospective and few prospective studies support etomidate's safety and efficacy in pediatric procedural sedation.The objective was to compare etomidate/fentanyl (E/F) with ketamine/midazolam (K/M) for procedural sedation during orthopedic reductions in the PED.Prospective, partially blinded, randomized controlled study comparing intravenously administered K/M with intravenously administered E/F. A convenience sample of patients, aged 5

2010 Pediatric Emergency Care Controlled trial quality: uncertain

87. Epidural versus intravenous fentanyl for postoperative analgesia following orthopedic surgery: randomized controlled trial. (Abstract)

Epidural versus intravenous fentanyl for postoperative analgesia following orthopedic surgery: randomized controlled trial. Controversy exists regarding the site of action of fentanyl after epidural injection. The objective of this investigation was to compare the efficacy of epidural and intravenous fentanyl for orthopedic surgery.A randomized double-blind study was performed in Hospital São Paulo.During the postoperative period, in the presence of pain, 29 patients were divided into two

2010 São Paulo medical journal = Revista paulista de medicina Controlled trial quality: predicted high

88. Clinical comparison of 12 mg ropivacaine and 8 mg bupivacaine, both with 20 microg fentanyl, in spinal anaesthesia for major orthopaedic surgery in geriatric patients. Full Text available with Trip Pro

Clinical comparison of 12 mg ropivacaine and 8 mg bupivacaine, both with 20 microg fentanyl, in spinal anaesthesia for major orthopaedic surgery in geriatric patients. The aim of this study was to compare the haemodynamic and anaesthetic effects of 12 mg ropivacaine and 8 mg bupivacaine, both with 20 microg fentanyl, in spinal anaesthesia for major orthopaedic surgery in geriatric patients.Sixty American Society of Anesthesiologists (ASA) II-III patients scheduled for hip arthroplasty were (...) of ropivacaine and 8 mg of bupivacaine with 20 microg fentanyl in spinal anaesthesia can provide sufficient motor and sensory block for major orthopaedic surgery in geriatric patients. However, ropivacaine caused less motor block and haemodynamic side effects than bupivacaine during the procedure.Copyright 2010 S. Karger AG, Basel.

2010 Medical principles and practice : international journal of the Kuwait University, Health Science Centre Controlled trial quality: uncertain

89. [Effective skill training by means of E-learning in orthopaedic surgery]. (Abstract)

[Effective skill training by means of E-learning in orthopaedic surgery]. The effectiveness of e-learning for reporting of x-ray-findings in a prospective, randomized trial was tested.Twenty advanced medical students were randomized into two groups. The test group practiced 4-6 hours with the newly developed software, the control group used conventional learning material. Afterwards, a test was carried out including 30 pathologic x-ray films that were randomly spread through 200 non-pathologic

2010 Zeitschrift für Orthopädie und Unfallchirurgie Controlled trial quality: uncertain

90. [Subarachnoid blockade with ropivacaine versus bupivacaine in urologic and orthopedic surgery]. (Abstract)

[Subarachnoid blockade with ropivacaine versus bupivacaine in urologic and orthopedic surgery]. To compare the effects of intrathecal isobaric ropivacaine (IR) versus isobaric bupivacaine (IB) in a dose ratio of 3:2 in non-ambulatory urologic and orthopedic surgery.One hundred and seventeen patients scheduled for surgery were randomized and assigned in a double-blind fashion to receive either 15 mg of IR (n = 58) or 10 mg of IB (n = 59) into the subarachnoid space.There were no differences

2010 Revista médica del Instituto Mexicano del Seguro Social Controlled trial quality: uncertain

91. [Return to work following work-related orthopaedic rehabilitation: a cluster randomized trial]. (Abstract)

[Return to work following work-related orthopaedic rehabilitation: a cluster randomized trial]. Since the 1990s work-related programmes became more important in orthopaedic rehabilitation. However, in Germany orthopaedic rehabilitation initially focussed on improvements in evaluating functional capacity and on the development of appropriate modules of exercise therapy while psychosocial work demands have been less considered in the rehabilitation process so far.Aims of the study were (...) implementation and efficacy evaluation of an intensified multimodal work-related programme following a cognitive behavioural approach.Participants were patients with substantial work-related problems. Included patients were randomized in groups either to the work-related programme or to the common orthopaedic rehabilitation (cluster randomization). Primary outcome was return to work. Analyses were based on post-treatment data and data after six months.236 (86.8%) patients consented to participate

2010 Die Rehabilitation Controlled trial quality: uncertain

92. A multicenter, randomized, triple-masked, placebo-controlled trial of the effect of ambulatory continuous femoral nerve blocks on discharge-readiness following total knee arthroplasty in patients on general orthopaedic wards. Full Text available with Trip Pro

A multicenter, randomized, triple-masked, placebo-controlled trial of the effect of ambulatory continuous femoral nerve blocks on discharge-readiness following total knee arthroplasty in patients on general orthopaedic wards. A continuous femoral nerve block (cFNB) involves the percutaneous insertion of a catheter adjacent to the femoral nerve, followed by a local anesthetic infusion, improving analgesia following total knee arthroplasty (TKA). Portable infusion pumps allow infusion

2010 Pain Controlled trial quality: predicted high

93. A randomized comparison of transfusion triggers in elective orthopaedic surgery using leucocyte-depleted red blood cells. (Abstract)

A randomized comparison of transfusion triggers in elective orthopaedic surgery using leucocyte-depleted red blood cells. In elective orthopaedic hip- and knee replacement surgery patients, we studied the effect of implementation of a uniform transfusion policy on RBC usage.A randomized, controlled study. A new uniform, restrictive transfusion policy was compared with standard care, which varied among the three participating hospitals. Only prestorage leucocyte-depleted RBC(s) were used

2010 Vox sanguinis Controlled trial quality: uncertain

94. Resistive-polymer versus forced-air warming: comparable efficacy in orthopedic patients. Full Text available with Trip Pro

Resistive-polymer versus forced-air warming: comparable efficacy in orthopedic patients. Several adverse consequences are caused by mild perioperative hypothermia. Maintaining normothermia with patient warming systems, today mostly with forced air (FA), has thus become a standard procedure during anesthesia. Recently, a polymer-based resistive patient warming system was developed. We compared the efficacy of a widely distributed FA system with the resistive-polymer (RP) system in a prospective (...) , randomized clinical study.Eighty patients scheduled for orthopedic surgery were randomized to either FA warming (Bair Hugger warming blanket #522 and blower #750, Arizant, Eden Prairie, MN) or RP warming (Hot Dog Multi-Position Blanket and Hot Dog controller, Augustine Biomedical, Eden Prairie, MN). Core temperature, skin temperature (head, upper and lower arm, chest, abdomen, back, thigh, and calf), and room temperature (general and near the patient) were recorded continuously.After an initial decrease

2010 Anesthesia and analgesia Controlled trial quality: uncertain

95. Revised cardiac risk index and postoperative morbidity after elective orthopaedic surgery: a prospective cohort study. Full Text available with Trip Pro

Revised cardiac risk index and postoperative morbidity after elective orthopaedic surgery: a prospective cohort study. The revised cardiac risk index (RCRI) is associated strongly with increased cardiac ischaemic risk and perioperative death. Associations with non-cardiac morbidity in non-cardiac surgery have not been explored. In the elective orthopaedic surgical population, morbidity is common but preoperative predictors are unclear. We hypothesized that RCRI would identify individuals (...) significant associations with hospital stay, as measured by the area under the receiver-operating characteristic curves for mRCRI 0.64 (95% CI: 0.58-0.70) and POSSUM 0.70 (95% CI: 0.63-0.75).mRCRI score ≥ 3 is associated with increased postoperative non-cardiac morbidity and prolonged hospital stay after elective orthopaedic procedures. mRCRI can contribute to objective risk stratification of postoperative morbidity.

2010 British Journal of Anaesthesia

96. Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic Surgery. (Abstract)

Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic Surgery. Reduced estimated glomerular filtration rate (eGFR) is strongly associated with increased cardiovascular risk and all-cause mortality. Associations with morbidity in elective, moderate-risk noncardiac surgery have not been explored. We hypothesized that chronic kidney disease (CKD) would be associated with excess morbidity after elective, moderate-risk orthopedic surgery.Patients undergoing elective orthopedic (...) ), both between and within CKD compared with normal renal function patients. Multiple regression analysis was performed to assess the association of CKD, perioperative factors with morbidity, and length of hospital stay.Postoperative morbidity survey was recorded in 526 patients undergoing elective orthopedic surgery. CKD patients (n = 142; 27%) sustained excess morbidity on postoperative day 5 (OR 2.1 [95% CI: 1.2-3.7]; P < 0.0001). CKD patients took longer (HR 1.6 [95% CI: 1.2-1.9]) to become

2010 Anesthesia and Analgesia

97. A review of the use of common antiplatelet agents in orthopaedic practice. Full Text available with Trip Pro

A review of the use of common antiplatelet agents in orthopaedic practice. Antiplatelet agents are widely prescribed for the primary and secondary prevention of cardiovascular events. A common clinical problem facing orthopaedic and trauma surgeons is how to manage patients receiving these agents who require surgery, either electively or following trauma. The dilemma is to balance the risk of increased blood loss if the antiplatelet agents are continued peri-operatively against the risk

2010 The Journal of Bone and Joint Surgery British Volume

98. Quality of Postoperative Care after Major Orthopedic Surgery Is Correlated with Both Long-term Cardiovascular Outcome and Troponin Ic Elevation. (Abstract)

Quality of Postoperative Care after Major Orthopedic Surgery Is Correlated with Both Long-term Cardiovascular Outcome and Troponin Ic Elevation. The aim of this study performed in patients undergoing major orthopedic surgery was to assess the impact of changes in practice on both the incidence of postoperative myocardial ischemia (PMI) detected by serial measurements of troponin Ic and long-term cardiac outcome.During a 3-yr period, troponin Ic was measured on the first 3 days after major (...) orthopedic surgery in a multidisciplinary hospital. After 16 months of study, postoperative care was improved. Cardiac death, myocardial infarction, and cardiac failure were considered major adverse cardiac events and were recorded during the hospital stay and the first postoperative year. The incidences of PMI and major adverse cardiac events were used as result indicators for quality of care and compared before (P1) and after (P2) quality enhancement.Three hundred seventy-eight surgical procedures were

2010 Anesthesiology

99. Orthopaedic sequelae of childhood meningococcemia: management considerations and outcome. (Abstract)

Orthopaedic sequelae of childhood meningococcemia: management considerations and outcome. Patients who survive the initial acute phase of fulminant meningococcemia are at increased risk for serious orthopaedic complications. This report describes our experience with purpura fulminans related to meningococcemia, with emphasis on musculoskeletal sequelae and their treatment.We retrospectively reviewed the cases of forty-eight patients (twenty-two boys and twenty-six girls) who survived the acute (...) extremities was similar to that in the lower extremities. Eight patients (17%) acquired soft-tissue and bone infections at the distal portion of the amputation stump, at a mean of 7.2 ± 5.4 years after the initial sepsis. Thirteen patients (27%) were found to have developmental delay at the time of follow-up, and it was severe in seven of them.All patients who survive meningococcal septicemia should be followed by an orthopaedic surgeon who is experienced in pediatric limb deformities and amputations

2010 The Journal of Bone and Joint Surgery. American Volume

100. Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients. (Abstract)

Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients. Deep venous thrombosis (DVT) and pulmonary embolism (PE) are possible sources of morbidity and mortality in patients with musculoskeletal neoplasms (MSN).To compare the efficacy of aspirin (ASA) and pneumatic compression devices (PCD) to low-molecular-weight heparin (LMWH) and PCD in patients undergoing orthopedic procedures for MSN of the pelvis or lower extremity.Of (...) arthroplasty, procedures of the hip/pelvis, and metastatic disease were more often managed with LMWH/PCD.DVT prophylaxis in orthopedic oncology remains a complex topic in which physicians must balance the risks of thromboembolic disease against the risks of post-operative complications.2010 Wiley-Liss, Inc.

2010 Journal of Surgical Oncology

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