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61. Optimal Exercise Programs for Patients With Peripheral Artery Disease: A Scientific Statement From the American Heart Association

as a reproducible discomfort or fatigue in the muscles of the lower extremity that occurs with exertion and is relieved within 10 minutes of rest. Most people with PAD do not have classic claudication symptoms but still have significantly greater functional impairment and decline than people without PAD. This significant physical activity limitation results in functional impairment, mobility loss, and decreased quality of life. Improving functioning and quality of life is a major goal in the treatment (...) in functional status and HRQOL. Individuals with PAD often avoid physical activity, especially walking. Their sedentary lifestyle leads to additional declines in functional status and HRQOL, as well as cardiovascular health. , , , Measures of objective and subjective functioning and HRQOL commonly used in patients with PAD are presented in the Outcome Measures section of this statement. Mechanisms of Training Response to Exercise in Patients With PAD The pathophysiological mechanisms underlying

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2019 American Gastroenterological Association Institute

62. Care of Women with Obesity in Pregnancy

, lactating women on the growth of their infants. N Engl J Med 2000;342:449–53. 187. O’Toole ML, Sawicki MA, Artal R. Structured diet and physical activity prevent postpartum weight retention. J Womens Health (Larchmt) 2003;12:991–8. RCOG Green-top Guideline No. 126 e102 of e106 ª 2018 Royal College of Obstetricians and Gynaecologists188. Bellamy L, Casas JP, Hingorani AD, Williams D. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta- analysis. Lancet 2009;373:1773–9. 189 (...) according to RCOG GTG No. 37b. P What special considerations are recommended for screening, diagnosis and management of mental health problems in women with obesity? Women with BMI 30 kg/m 2 or greater are at increased risk of mental health problems and should therefore be screened for these in pregnancy. D There is insuf?cient evidence to recommend a speci?c lifestyle intervention to prevent depression and anxiety in obese pregnant women. P Antenatal screening What special considerations does maternal

2018 Royal College of Obstetricians and Gynaecologists

63. Managing health and wellbeing in the workplace

analysis by category is shown below as Figure 5. ‘Physical Activity’ focussed (including sedentary behaviour) studies were the most numerous (39 or 11% of the total), followed by Mental Health/Stress (34 or 10% of total). Alcohol (3) was the category with the fewest retrieved studies. Studies conducted in Australia/by Australian researchers (34) made up 10% of retrieved studies in this bibliometric analysis. Figure 6 - Bibliometric analysis of studies 2007-2017 by strategic theme A bibliometric (...) IN THE WORKPLACE| SAX INSTITUTE Factors driving workplace wellness programs Table 1 shows the main drivers of wellness program design (in terms of modifiable risks and issues). Physical activity and stress are the top priorities globally and in Australia. Workplace safety is of highest importance in Asia, Africa/Middle East and Latin America. Figure 4 shows the fasting growing program components and especially the growth of telephonic support and lifestyle coaching services. 3 Table 1 - Extent to which certain

2018 Sax Institute Evidence Check

64. Enhancing Health Promotion and Disease Prevention in Networked Primary Care

public-health service providers; community-health service providers (e.g., mental health, substance use and home-care service providers); and other health organizations (e.g., community health centres, non-government organizations and the First Nations Health Authority). The eight core attributes of primary-care networks, as outlined by the General Practice Services Committee (one of four joint collaborative committees that represent a partnership between the Government of British Columbia (...) systematic reviews of the research literature and occasionally from single research studies. A systematic review is a summary of studies addressing a clearly formulated question that uses systematic and explicit methods to identify, select and appraise research studies, and to synthesize data from the included studies. The rapid synthesis does not contain recommendations, which would have required the authors to make judgments based on their personal values and preferences. Rapid syntheses can

2018 McMaster Health Forum

65. Depression and anxiety programs for children and young people

programs on child internalising problems, anxiety and depression are unknown due to a lack of evaluation. Given that bullying prevention programs are theoretically linked to mental health benefits for both perpetrators and victims, future bullying prevention evaluations should investigate these effects. The present review identified evaluations of physical activity interventions. However, there is evidence that other healthy lifestyle factors, such as good nutrition and sleep and avoiding substance (...) psychological interventions, although the returns are lower than widely implemented health care interventions. DEPRESSION AND ANXIETY PROGRAMS FOR CHILDREN AND YOUNG PEOPLE | SAX INSTITUTE 7 Six other programs were identified as having sufficient evidence to warrant a 2 or 3 thumb rating. These were: Coping Cat ( ? ? ?); Families and Schools Together ( ? ?); Physical activity interventions ( ? ?); the Good Behaviour Game ( ? ?); Mentoring ( ? ?); and Online CBT ( ? ?). All of these programs have been

2018 Sax Institute Evidence Check

66. Bioresorbable Stents in cardiovascular indications (coronary artery disease)

or unstable CAD. CAD is a prevalent disease defined as the manifestation of arteriosclerosis in the coronary arteries and is the leading cause of death in Europe [6]. Risk factors for CAD that can be controlled are smoking, high alcohol consumption, lack of physical activity, high blood cholesterol levels, overweight or obe- sity, diabetes mellitus, hypertension and psychosocial burden, such as stress or depression [7-9]. Patients with CAD have an elevated risk for myocardial infarction (MI), cardiac (...) TABLE OF CONTENTS LIST OF ABBREVIATIONS 6 SUMMARY OF THE RELATIVE EFFECTIVENESS OF BIORESORBABLE STENTS FOR THE TREATMENT OF CARDIOVASCULAR INDICATIONS (CORONARY ARTERY DISEASE) 8 SCOPE 8 INTRODUCTION 8 METHODS 9 RESULTS 10 DISCUSSION 12 CONCLUSION 13 1 SCOPE 18 2 METHODS AND EVIDENCE INCLUDED 20 2.1 ASSESSMENT TEAM 20 2.2 SOURCE OF ASSESSMENT ELEMENTS 20 2.3 SEARCH 20 2.4 STUDY SELECTION 21 2.5 DATA EXTRACTION AND ANALYSES 23 2.6 QUALITY RATING 23 2.7 DESCRIPTION OF THE EVIDENCE USED 23 2.8

2019 EUnetHTA

67. Withdrawal Management Services in Canada: The National Treatment Indicators Report

use the International Statistical Classification of Disease and Related Health Problems, 10 th revision (ICD-10-CA) (Canadian Institute for Health Information, 2015) (see Appendix E). The OMHRS and HMHS report diagnoses codes that are based on the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision (DSM-IV-TR). While most provinces and territories only use ICD-10-CA, the hospital data from Ontario contain records coded using both ICD- 10-CA and DSM-IV-TR (...) provincial and territorial-level WM data. Within Indigenous Services Canada’s Mental Wellness Program, the Youth Solvent Addictions Committee and the Thunderbird Partnership Foundation also provided information about some treatment services pertaining to First Nations. A variety of different systems, methods and processes were used to collect this information across Canada. Generally, a substantial amount of service and client information is collected at the point of screening and assessment or intake

2019 Canadian Centre on Substance Abuse

68. Developing a Value Framework for Genetic Diagnosis: Part I A Systematic Review of Outcomes Hierarchies and Measurement Approaches

Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the American College of Medical Genetics. ACMG Value Review, March 16, 2012 Page 2 TABLE OF CONTENTS Commonly Used Acronyms and Abbreviations 4 Executive Summary 5-9 Introduction 10-13 Background and Context 10 Purpose and Scope 11 Methods 14-19 Key Questions and Review Framework 14 Search Strategy 16 Change in Scope of Review 16 Data Abstraction 17 Data Analysis 17 (...) PROs Patient-reported outcomes QA Quality assurance QALY Quality adjusted life year QI Quality improvement QOF UK Quality Outcomes Framework QOL Quality of life QSR Qualitative Systematic Review RW “real world”, as in “RW data” SER Systematic evidence review TEP Technical Expert Panel UK NHS UK National Health Service US United States ACMG Value Review, March 16, 2012 Page 5 EXECUTIVE SUMMARY Introduction This qualitative systematic review was commissioned by the American College of Medical

2019 American College of Medical Genetics and Genomics

69. WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights

the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights. Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data. CIP data are available at Sales, rights and licensing. To purchase WHO publications, see (...) in the preparation of this guideline 133 Annex 2: Existing recommendations for noncommunicable diseases (NCDs) 135 Annex 3: Scoping review: WHO self-care definitions Annex 8: Guideline Development Group (GDG) judgements related to the new recommendations 149 152 Annex 6: Priority questions and outcomes for the interventions identified for this guideline Web annex: GRADE tables (available at: reproductivehealth/self- care-interventions/en/) 138 Annex 4: Glossary 151 Annex 7: List of reviews

2019 World Health Organisation Guidelines

71. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease

and Science University to perform rapid systematic evidence reviews for 5 of the key topics: aspirin use, T2DM, nutrition and diet, obesity and weight loss, and tobacco use. In parallel, an independent health data and epidemiology expert, Lee Ann Prebil, conducted a systematic evidence review for the key topic of exercise and physical activity and conducted targeted literature searches to support this document’s discussion of patient-centered approaches, including team-based care, shared decision-making (...) Prevention of Cardiovascular Disease Page 21 of 98 3.2. Exercise and Physical Activity Recommendations for Exercise and Physical Activity Referenced studies that support recommendations are summarized in Online Data Supplements 6 and 7. COR LOE Recommendations I B-R 1. Adults should be routinely counseled in healthcare visits to optimize a physically active lifestyle (S3.2-1, S3.2-2). I B-NR 2. Adults should engage in at least 150 minutes per week of accumulated moderate-intensity or 75 minutes per week

2019 American Heart Association

72. Testicular Cancer

., et al. Going from evidence to recommendations. BMJ, 2008. 336: 1049. 6. La Vecchia, C., et al. Cancer mortality in Europe, 2000-2004, and an overview of trends since 1975. Ann Oncol, 2010. 21: 1323. 7. Jemal, A., et al. Cancer statistics, 2009. CA Cancer J Clin, 2009. 59: 225. 8. Nigam, M., et al. Increasing incidence of testicular cancer in the United States and Europe between 1992 and 2009. World J Urol, 2014. 33: 623. 9. Ghazarian, A.A., et al. Recent trends in the incidence of testicular germ (...) of metachronous contralateral testicular germ cell tumours. Br J Cancer, 2012. 107: 1637. 32. Lerro, C.C., et al. A systematic review and meta-analysis of the relationship between body size and testicular cancer. Br J Cancer, 2010. 103: 1467. 33. Brierley, J.E., et al., The TNM Classification of Malignant Tumours 8th edition. 2016. 34. Peyret, C. Tumeurs du testicule. Synthèse et recommandations en onco-urologie. [Testicular tumours. Summary of onco-urological recommendations] [Article in French]. Prog Urol

2019 European Association of Urology

73. Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review

osteoporosis drug treatment (ODT) and ODT discontinuation and holidays on fractures and harms. Data sources. MEDLINE ® , Embase ® , and Cochrane databases from 1995 to October 2018;; bibliographies of relevant systematic reviews. Review methods. We defined long-term ODT as >3 years and ODT holidays as discontinuation for =1 year after =1 year of use. Trials were used for incident fractures and harms, and controlled observational studies were included for additional harms. Two (...) investigators rated risk of bias. For studies with low or medium risk of bias, one investigator extracted data and a second verified accuracy. Two investigators graded strength of evidence (SOE). Results. Sixty-one English-language studies were included. In women with osteoporosis, 4 years of alendronate reduced clinical fractures (hazard ratio [HR] 0.64 [95% confidence interval (CI) 0.50, 0.82]) (moderate SOE) and radiographic vertebral fractures (HR 0.50 [95% CI 0.31, 0.82]) (moderate SOE), while 4 years

2019 Effective Health Care Program (AHRQ)

74. Management of Infertility

to polycystic ovary syndrome (PCOS), endometriosis, unknown reasons, or tubal or peritoneal factors or (b) couples with male factor infertility, and evaluated short- and long-term health outcomes of gamete donors in infertility. Data sources. We searched PubMed ® , Embase ® , and the Cochrane Database of Systematic Reviews for English-language studies published from January 1, 2007, to October 3, 2018, that reported live birth rates, pregnancy and neonatal outcomes, time to pregnancy, and short-term (...) and long-term adverse outcomes for mothers and children born after infertility treatment. For male and female donors, we searched for studies reporting short- and long-term adverse effects and quality-of-life outcomes. Review methods. Two investigators screened each abstract and full-text article for inclusion; abstracted data; and performed quality ratings, applicability ratings, and evidence grading. Where appropriate, random-effects models were used to compute summary estimates of effects. Results

2019 Effective Health Care Program (AHRQ)

75. Prevention and early intervention for adults with mild to moderate depression

interventions currently being used within the National Health System (NHS) in England, UK. Data for the review was obtained using a survey of NHS Mental Health Trusts across England, via Freedom of Information requests for Improving Access to Psychological Therapies (IAPT) services, and a systematic search of the NHS apps library. Results identified that 13 different web apps and 35 smartphone apps for depression, stress and anxiety were being used and made available through IAPT, NHS Apps Library (...) the benefits of technology-based peer support. At the time of the review, barriers to using mobile apps included low bandwidth, disengagement and loss of interest, concerns around privacy and data storage, and concerns about clinical risk and cybersafety of peers and participants interacting in this environment. Significant advances in technology and security have occurred since 2014, potentially increasing the potential of this technology in managing and delivering peer interventions for mental health

2018 Sax Institute Evidence Check

76. Addressing Social Isolation To Improve the Health of Older Adults: A Rapid Review

evaluated physical activity interventions in older adults. Two RCTs 46, 48 reported health benefits, both of which were multicomponent interventions that combined exercise with other interventions including social, leisure activities (e.g. cooking), and/or diet programming. One RCT (n=77) 48 examined a 3-month, twice-weekly, 100-minute resistance exercise program combined with either a nutritional or psychosocial program. This 8 intervention was delivered to pre-frail or frail older adults by trainers (...) . This study involved a 3-month multicomponent intervention delivered at a community center, but was conducted less frequently (once a week vs. twice a week). This intervention included two-hour sessions once a week of physical activity (e.g., walking, stretching, and weights) combined with leisure activities (e.g., cooking, games, and crafts). This study found no effect on social support but did report significant improvement in quality of life at 3 months. This intervention was delivered by health care

2019 Effective Health Care Program (AHRQ)

77. Primary Prevention of Cardiovascular Disease

development process. Avalere Health commissioned the Pacific Northwest Evidence-based Practice Center at Oregon Health and Science University to perform rapid systematic evidence reviews for 5 of the key topics: aspirin use, T2DM, nutrition and diet, obesity and weight loss, and tobacco use. In parallel, an independent health data and epidemiology expert, Lee Ann Prebil, conducted a systematic evidence review for the key topic of exercise and physical activity and conducted targeted literature searches (...) for Exercise and Physical Activity Referenced studies that support recommendations are summarized in Online Data Supplements 6 and 7. COR LOE Recommendations I B-R 1. Adults should be routinely counseled in healthcare visits to optimize a physically active lifestyle (S3.2-1, S3.2-2). I B-NR 2. Adults should engage in at least 150 minutes per week of accumulated moderate-intensity or 75 minutes per week of vigorous-intensity aerobic physical activity (or an equivalent combination of moderate and vigorous

2019 American College of Cardiology

78. Contraceptive Choices for Young People

factors: individual factors (knowledge, attitude, personal aspirations, previous use, perceived risk); familial (family structure, parent–child relationship, socioeconomic status); relationship (partner characteristics) and social (social norms, peer influences, access to services). 12,26–30 In the UK, the contraceptive pill and condom remain the two most commonly used methods. Office of National Statistics survey data (2008/2009) 31 indicate that among women aged 16–29 years who were at risk (...) that use of EC may be influenced by factors such as perceived pregnancy risk, personal and perceived attitudes towards EC and confidence in asking for it. 50–52 Data from the Office of National Statistics indicates that whilst 86% of individuals aged 16–19 years had heard of emergency hormonal contraception, only 35% had heard of the emergency intrauterine device (IUD). 48 There are now three methods of EC available in the UK: POEC, the copper-bearing intrauterine device (Cu-IUD), and the progesterone

2019 Faculty of Sexual & Reproductive Healthcare

79. Guidance on the clinical management of anxiety disorders, specifically focusing on diagnosis and treatment strategies

always produces distress, anxiety disorders can be disabling. Data from the Australian National Survey of Mental Health and Wellbeing (Slade et al., 2009b) dem- onstrate significant disruption to everyday life among peo- ple who met criteria for current panic disorder, SAD or GAD as their principal complaint; the number of days unable to work or do normal tasks due to anxiety during the previous month was reported as less than 1 day by approximately half, 1–7 days by one-third, and more than 7 days (...) be experienced as normal when they are consistent with the demands of the situation. Anxiety disorders, like all mental disorders, lie on dimen- sions that extend from transient symptoms, to symptoms that are severe, disabling and persist for years. The threshold on this dimension at which a disorder is defined is specified in the diagnostic criteria listed by International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10; World Health Organization, 1993, 2016

2018 Royal Australian and New Zealand College of Psychiatrists

80. Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD

about the effectiveness and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (ECOPD). Data sources. Embase ® , Epub Ahead of Print, In-Process & Other Non-Indexed Citations, MEDLINE ® Daily, MEDLINE, Cochrane Central Registrar of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus from database inception to January 2, 2019. Review methods. We included randomized controlled trials (RCTs) that evaluated (...) pharmacologic intervention or nonpharmacologic interventions for ECOPD. The strength of evidence (SOE) was graded for critical final health outcomes. Results. We included 98 RCTs (13,401 patients, mean treatment duration 9.9 days, mean followup 3.7 months). Final health outcomes, including mortality, resolution of exacerbation, hospital readmissions, repeat exacerbations, and need for intubation, were infrequently evaluated and often showed no statistically significant differences between groups. Antibiotic

2019 Effective Health Care Program (AHRQ)

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