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121. Canada's Low-Risk Alcohol Drinking Guidelines: Communications Toolkit

are: driving a vehicle or using machinery and tools • taking medicine or other drugs that interact with alcohol • Doing any kind of dangerous physical activity • living with mental or physical health problems • living with alcohol dependence • pregnant or planning to be pregnant • responsible for the safety of others • making important decisions PREGNANT? ZERO IS SAFEST If you are pregnant or planning to become pregnant, or about to breastfeed, the safest choice is to drink no alcohol at all. DELAY YOUR (...) not start to drink or increase your drinking for health benefits. Low-risk drinking helps to promote a culture of moderation. Low-risk drinking supports healthy lifestyles. 500–75 Albert Street, Ottawa, ON K1P 5E7 Tel: 613-235-4048 | Fax: 613-235-8101 Charitable #: 122328750RR0001 Developed on behalf of the National Alcohol Strategy Advisory Committee © Canadian Centre on Substance Use and Addiction 2018 Cette publication est également disponible en français. The Canadian Centre on Substance Abuse

2018 Canadian Centre on Substance Abuse

122. What is the evidence on existing policies and linked activities and their effectiveness for improving health literacy at national, regional and organizational levels in the WHO European Region?

Health, School of Public Health, University of Sydney, Australiavi vi External peer reviewers Jürgen M. Pelikan Emeritus Professor of Sociology, University of Vienna, and Director, Competence Center Health Promotion in Hospitals and Health Care, Gesundheit Österreich GmbH, Vienna, Austria Stephan Van den Broucke Professor of Public Health Psychology, Institut de Recherche en Sciences Psychologiques, Faculté de Psychologie et des Sciences de l'Education, Université Catholique de Louvain, Louvain-la (...) for which both the strategy and the funding are devolved from the Member State to the individual country or semiautonomous region.ix Policies were examined to (i) describe the policy stages; and (ii) analyse the components (antecedents, actors, activities and beneficiaries) and activities using a new framework, the Health Literacy Policy Model. A wide range of activities was identified at international, national and local levels. Baseline health literacy data are not available in all Member States

2018 WHO Health Evidence Network

123. Improving Quality of Life: Substance Use and Aging

of alcohol and drug terms. Retrieved from 4 American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, (5 th ed.). Washington, D.C.: American Psychiatric Publishing.Canadian Centre on Substance Use and Addiction 9 Substance Use and Successful Aging: Key Issues and Considerations 01 CHAPTER AT A GLANCE • Older adults represent the fastest growing segment of society. In Canada, the aging population is expected (...) be downloaded as a PDF at Ce document est également disponible en français sous le titre : Usage de substances au Canada : Meilleure qualité de vie : usage de substances et vieillissement.Substance Use In Canada—Improving Quality of Life: Substance Use and Aging Canadian Centre on Substance Use and Addiction 1 Canada is getting older. According to Statistics Canada, the share of our population made up of older adults will grow from just under 15% in 2010 to more than 25% in 2036

2018 Canadian Centre on Substance Abuse

124. Cardiovascular Disease and Breast Cancer: Where These Entities Intersect: A Scientific Statement From the American Heart Association

physical activity, those who reported high lifetime recreational physical activity had a significantly lower risk of breast cancer–related death (HR, 0.73; 95% CI, 0.54–0.98). Additionally, significant risk reduction for breast cancer–related death was demonstrated in women who had engaged in recreational physical activity more recently before diagnosis (HR, 0.84; 95% CI, 0.73–0.97). In NHSII, data showed that physical activity at ages 14 to 17 years was associated with a 15% lower risk (...) factors ( ). Cardiovascular clinical care and research have focused on risk factors for >60 years, because it is believed that ≈80% of CVD can be prevented through risk factor modifications such as promoting a healthy diet, physical activity, and a healthy weight; abstinence from tobacco; blood pressure control; diabetes mellitus management; and a good lipid profile. Adherence to a larger number of ideal cardiovascular health behaviors or factors from the American Heart Association’s Life’s Simple 7

2018 American Heart Association

125. Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency

recommend increasing the glucocorticoid dosage. (1|⊕⊕⊕○) 4.8 In patients with congenital adrenal hyperplasia under everyday mental and emotional stress and minor illness and/or before routine physical exercise we recommend against the use of increased glucocorticoid doses. (1|⊕⊕○○) 4.9 In patients with congenital adrenal hyperplasia who require treatment, we recommend always wearing or carrying medical identification indicating that they have adrenal insufficiency. (1|⊕⊕⊕○) 4.10 In patients (...) be performed only in centers with experienced pediatric surgeons/urologists, pediatric endocrinologists, pediatric anesthesiologists, behavioral/mental health professionals, and social work services. Extensive discussions regarding risks and benefits, shared decision-making, review of potential complications, and fully informed consent need to occur prior to surgery. The option to forgo surgery should be considered. 7.2 In severely virilized females, we advise discussion about early surgery to repair

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2018 Pediatric Endocrine Society

126. Relative effectiveness assessment of Femtosecond laser-assisted cataract surgery (FLACS) compared to standard ultrasound phacoemulsification cataract surgery

no difference between study arms). Data from two studies (25,28) assessing refractive outcomes were used for the analysis and pooled estimate showed no difference between study groups. [D0006] At one week, one study found a marginally significant and not clinically relevant difference (less than 0.1 log MAR varia- tion) in favour of FLACS, while the second study found no statistically significant difference be- tween the two study arms. At one month, neither study found a statistically significant result (...) AND EVIDENCE INCLUDED 23 ASSESSMENT TEAM 23 PATIENTS’ INVOLVEMENT 27 SOURCE OF ASSESSMENT ELEMENTS 27 SEARCH 27 STUDY SELECTION 28 DATA EXTRACTION AND ANALYSES 30 QUALITY RATING 31 PATIENT INVOLVEMENT 32 DESCRIPTION OF THE EVIDENCE USED 32 DEVIATIONS FROM PROJECT PLAN 41 DESCRIPTION AND TECHNICAL CHARACTERISTICS OF TECHNOLOGY (TEC) 42 RESEARCH QUESTIONS 42 HEALTH PROBLEM AND CURRENT USE OF THE TECHNOLOGY (CUR) 55 RESEARCH QUESTIONS 55 RESULTS 55 CLINICAL EFFECTIVENESS (EFF) 71 RESEARCH QUESTIONS 71 RESULTS

2018 EUnetHTA

128. Testicular Cancer

., et al. Going from evidence to recommendations. BMJ, 2008. 336: 1049. 6. La Vecchia, C., et al. Cancer mortality in Europe, 2000-2004, and an overview of trends since 1975. Ann Oncol, 2010. 21: 1323. 7. Jemal, A., et al. Cancer statistics, 2009. CA Cancer J Clin, 2009. 59: 225. 8. Nigam, M., et al. Increasing incidence of testicular cancer in the United States and Europe between 1992 and 2009. World J Urol, 2014. 33: 623. 9. Ghazarian, A.A., et al. Recent trends in the incidence of testicular germ (...) of metachronous contralateral testicular germ cell tumours. Br J Cancer, 2012. 107: 1637. 32. Lerro, C.C., et al. A systematic review and meta-analysis of the relationship between body size and testicular cancer. Br J Cancer, 2010. 103: 1467. 33. Brierley, J.E., et al., The TNM Classification of Malignant Tumours 8th edition. 2016. 34. Peyret, C. Tumeurs du testicule. Synthèse et recommandations en onco-urologie. [Testicular tumours. Summary of onco-urological recommendations] [Article in French]. Prog Urol

2018 European Association of Urology

129. Assessment and Interventions for Perinatal Depression

within the first year following childbirth (23, 29). Criteria of symptoms of perinatal depression are varied, depending on the source. For example, the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders - 5 (DSM-5) identifies perinatal depression as a type of major depressive disorder with a peripartum onset, and symptoms occurring on a daily or near-daily basis over a two- week time frame or longer (29). Criteria for a diagnosis of perinatal depression, according to the DSM-5 (...) for developing policy or securing the supports required within health-care organizations for implementing best practices. Recommendations in the three areas (practice, education, and organization and system policy) focus on evidence- based strategies that nurses and the interprofessional team require for perinatal depression screening, assessment, prevention, interventions, and evaluation. Additionally, the recommendations describe the necessary resources for coordinated mental health services and supports

2018 Registered Nurses' Association of Ontario

130. Exploratory steps for the formulation of Belgian health system targets

(and their replacement with polyunsaturated fats) ? Increase the rate of exclusive breastfeeding in the first six months of life to at least 50% WHO targets on Noncommunicable Diseases 12 , WHO 33 , WHO regional office for Europe 34, 31 Lifestyles : Physical activity ? By 2025, a 10% relative reduction in prevalence of insufficient physical activity WHO targets on Noncommunicable Diseases 12 22 Exploratory steps for the formulation of Belgian health system targets KCE Report 292 Lifestyles : Substance abuse ? 200 (...) Santé et du Social de Bruxelles-Capitale), Joeri Guillaume (Socialistische Mutualiteiten), Catherine Le Gales (Institut Francilien Recherche Innovation Société [IFRIS], France), Murielle Lona (Mutualités Libres), Alain Piette (SPF Emploi – FOD Werkgelegenheid), Françoise Renard (ISP – WIV), Rik Thys (Socialistische Mutualiteiten), Saskia Van den Bogaert (FOD Volksgezondheid – SPF Santé Publique), Pieter Vandenbulcke (Vlaams Agentschap Zorg en Gezondheid), Stephan Van den Broucke (UCL), Johan Van Der

2017 Belgian Health Care Knowledge Centre

131. Low back pain and radicular pain: development of a clinical pathway

METHODS 22 3.2.1 Identification of eligible pathways and countries 22 3.2.2 Identification of variables relevant to the quality, efficacy, feasibility and applicability of low back pain care pathways 23 3.2.3 Data collection 23 2 Low back pain and radicular pain: development of a clinical pathway KCE Report 295 3.2.4 Processing and analysis of the data 24 3.3 RESULTS 24 3.3.1 Number of identified pathways 24 3.3.2 Characteristics of retrieved pathways 26 3.3.3 Pathway components related to quality (...) : A STEPWISE PROCESS PROVIDES A ROLE TO EACH TYPE OF HEALTHCARE PROVIDER 103 8.6.1 The primary care should be reinforced 103 8.6.2 The referral to the secondary care could be improved 107 KCE Report 295 Low back pain and radicular pain: development of a clinical pathway 5 8.6.3 Coordination of care is not optimal 108 8.7 FINDING 7: GATHERING DATA AND MONITORING SHOULD BE FORESEEN BEFORE THE PATHWAY IMPLEMENTATION 110 8.7.1 The COMI questionnaire 111 8.7.2 The ICHOM set of measures 112 9 BELGIAN PATHWAYS

2017 Belgian Health Care Knowledge Centre

132. Required hospital capacity in 2025 and criteria for rationalisation of complex cancer surgery, radiotherapy and maternity services

, the Netherlands; Ministerie van Gezondheid, Welzijn en Sport, Den Haag, the Netherlands), Florien Margareth Kruse (Celsus Academy for sustainable healthcare, IQ Healthcare, Radboud University Medical Center, Nijmegen, the Netherlands), Mélanie Lefèvre (KCE), Yolande Lievens (Departement Radiotherapie, UZ Gent; Universiteit Gent), Patriek Mistiaen (KCE), Aude Vaandering (Cliniques Universitaires Saint-Luc), Elizabeth Van Eycken (Stichting Kankerregister), Ewout van Ginneken (European Observatory on Health (...) (Association Francophone des Pharmaciens Hospitaliers de Belgique (AFPHB)), Christiaan Decoster (FOD Volksgezondheid – SPF Santé Publique), Dirk Dewolf (Vlaams Agentschap Zorg en Gezondheid), Thomas De Rijdt (Belgische Vereniging van Ziekenhuisapothekers (BVZA)), Michael Dufrane (Centrale générale des syndicats libéraux de Belgique (CGSLB)), Geneviève Durant (Agence pour une Vie de Qualité (AViQ)), Dieter Goemaere (Gezondheidsinstellingen Brussel Bruxelles Institutions de Santé (GIBBIS)), Liesbeth Haesaert

2017 Belgian Health Care Knowledge Centre

133. Low back pain and radicular pain: evaluation and management

for writing a publication or participating in its development: Luc Ailliet (grant for doctoral degree VU Amsterdam 2011 - 2015) Participation in scientific or experimental research as an initiator, principal investigator or researcher: Luc Ailliet (doctoral degree VU Amsterdam 2011 – 2015 «Rol van biopsychosociale factoren in het herstel van mensen met nekpijn en /of low back pain »), Anne Berquin (validation French version of questionnaire Örebro (OMPSQ)), Mieke Dolphens (investigator IWT-TBM financed (...) Interdisciplinaire Douleur HQE High quality evidence ICSI Institute for Clinical Systems Improvement (U.S) IDEWE Belgische Externe Dienst voor Preventie en Bescherming op het Werk i.e. Id est; that is IMA – AIM InterMutualistisch Agentschap – Agence Intermutualiste 8 Low back pain and radicular pain KCE Report 287 INAMI – RIZIV – NIHDI Institut National d’Assurance Maladie-Invalidité – Rijksinstituut voor Ziekte- en Invaliditeitsverzekering - National Institute for Health and Disability Insurance ISP – WIV

2017 Belgian Health Care Knowledge Centre

134. WHO Guidelines on Integrated Care for Older People (ICOPE)

/publications/essential_ncd_interventions_ lr_settings.pdf Guidelines for hearing aids and services for developing countries (2004): hearing_aid_guide_en.pdf Global recommendations on physical activity for health (2010): recommendations Evidence and recommendations 3 Most of the conditions selected for these integrated care for older people (ICOPE) guidelines share the same underlying factors and determinants. It may (...) plan, and all domains are assessed together. 2. Interventions to improve nutrition and encourage physical exercise are included in most of the care plans, and all the interventions needed are delivered in conjunction with each other. 3. The presence of any impairment/decline in capacity always triggers an urgent referral for medical assessment of the associated disease (examples being hypertension, diabetes, chronic obstructive pulmonary disease, and dementia). WHO has developed clinical guidelines

2017 World Health Organisation Guidelines

135. WHO recommendations on child health

on symptom-based screening and have no contact with a TB case should receive 6 months of IPT (10 mg/kg/day) as part of a comprehensive package of HIV prevention and care (strong recommendation, moderate-quality evidence). Source 10. NON-COMMUNICABLE DISEASES PREVENTION Physical activity ¦ ¦ Children and young people aged 5–17 years old should accumulate at least 60 minutes of moderate- to vigorous-intensity physical activity daily. Physical activity of amounts greater than 60 minutes daily will provide (...) additional health benefits. Most of daily physical activity should be aerobic. Vigorous-intensity activities should be incorporated, including those that strengthen muscle and bone, at least three times per week. (Strong recommendation, high quality evidence.) Source NEW Sugar Intakes ¦ ¦ WHO recommends a reduced intake of free sugars throughout the lifecourse (strong recommendation). — In both adults and children, WHO recommends reducing the intake of free sugars to less than 10% of total energy intake

2017 World Health Organisation Guidelines

136. WHO recommendations on adolescent health

and physical activity Tobacco 8. Violence and injury prevention 9. Prevention of mental health problems and promotion of mental health 10. Nutrition Management of adolescent conditions 11. HIV testing and counselling for adolescents living with HIV 12. Antiretroviral Therapy 13. Treatment of skin and oral HIV-associated conditions in children and adults 14. Treatment of sexually transmitted infections 15. Treatment of malaria 16. Treatment of malnutrition 17. Violence and injuries 18. Mental disorders 36 (...) Intellectual Property Organization. Suggested citation. WHO recommendations on adolescent health: guidelines approved by the WHO Guidelines Review Committee. Geneva: World Health Organization; 2017 (WHO/MCA/17.08). Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data. CIP data are available at Sales, rights and licensing. To purchase WHO publications, see To submit requests for commercial use and queries on rights and licensing, see

2017 World Health Organisation Guidelines

137. Improving Health and Wellbeing Outcomes in the Early Years

policies and actions to address the epidemic of childhood obesity through nutrition and physical activity plans are to be welcomed. Barriers and threats at the policy level • Although the direction is positive, it may need to move faster. There remain barriers to intersectoral and interdepartmental working. • There are gaps in data and research, including the long term effects of interventions that may take many years to emerge. • Sources of funding are expected to become scarce in the near future (...) of travel is likely to improve levels of physical activity with subsequent health benefits. In addition, many of the problems which adults experience have their origins in early childhood, which has implications for a wide range of social policies. Prevention and early intervention initiatives in the early years support today’s children to become healthy, socially and economically engaged adults in the future. Research demonstrates that the costs of unresolved childhood problems are borne by a range

2017 Institute of Public Health in Ireland

138. The National Alcohol Strategy Monitoring Project: A Status Report

Canadian Centre on Substance Use and Addiction, 2017. CCSA, 500–75 Albert Street Ottawa, ON K1P 5E7 Tel.: 613-235-4048 Email: Production of this document has been made possible through a financial contribution from Health Canada. The views expressed herein do not necessarily represent the views of Health Canada. This document can also be downloaded as a PDF at Ce document est également disponible en français sous le titre : Projet de surveillance de la Stratégie nationale sur (...) is to measure progress in the implementation of the NAS over time and how that progress translates into promoting moderation and reducing the overall harm from alcohol in Canada. Methods To ensure neutrality and objectivity in the development of this report, NASAC agreed to develop a monitoring strategy that would also guide the development of future reports. Monitoring is a systematic, ongoing process to collect, analyze and interpret accurate, up-to-date, relevant information from various data sources

2017 Canadian Centre on Substance Abuse

139. Investment for health and well-being: a review of the social return on investment from public health policies to support implementing the Sustainable Development Goals by building on Health 2020

(21–23).5 The conditions in which people live, work and age, and which shape their behaviour, are influenced by the distribution of money, power and resources at global, national and local levels. Investment that addresses this distribution is itself influenced by policy choices and will have impact on physical, mental and social well-being (13,24–26). Investing in the wider determinants of health drives health, well-being and resilience through influencing the social, cultural, political (...) of evidence to be reviewed if identified through the searches or provided by the contributors. The searches covered the period from 1 January 2007 to 1 January 2017. Searches were performed in February–March 2017. Additional documents answering the inclusion/exclusion criteria received from the contributors or peer reviewers were added during March–May 2017. 1.4.2. Data extraction A systematic scoping review of reviews was carried out using comprehensive search strategies adapted to the specific databases

2017 WHO Health Evidence Network

140. Key policies for addressing the social determinants of health and health inequities

or to inform more specific searches from which further documents were identified. The searches covered the period from 1 January 1997 to 31 March 2017. Searches were performed in February–March 2017. Additional documents identified through expert contributors, peer reviewers and snowballing were added during March–May 2017. Annex 1 outlines the search strategy in more detail. 1.3.2. Data extraction The searches identified a total of 211 records after duplicate removal. An additional 155 records were (...) universal, comprehensive ECEC, including issues of access, quality and staff training, along with the need for good data collection, research and evaluation of services. Refocus public investment on the early years Most countries spend a greater proportion of public money on older citizens; spending on children tends to focus on children after entry into compulsory education (24,25). Providing universal, comprehensive ECEC services requires investing more resources on the period from conception

2017 WHO Health Evidence Network

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