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81. Ulcerative colitis: management

Ulcerative colitis: management Ulcer Ulcerativ ative colitis: management e colitis: management NICE guideline Published: 3 May 2019 www.nice.org.uk/guidance/ng130 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement (...) of 28Recommendations Recommendations People have the right to be involved in discussions and make informed decisions about their care, as described in your care. Making decisions using NICE guidelines explains how we use words to show the strength (or certainty) of our recommendations, and has information about prescribing medicines (including off-label use), professional guidelines, standards and laws (including on consent and mental capacity), and safeguarding. 1.1 Patient information and support 1.1.1 Discuss

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

82. Cough (acute): antimicrobial prescribing

exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service. It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances of the individual, in consultation with them and their families and carers or guardian. Local commissioners and providers (...) ), but not compared with no treatment or dextromethorphan (low quality evidence). Honey had no significant effect on children's or parents' sleep quality compared with placebo or dextromethorphan, but was significantly better compared with no treatment or diphenhydramine (by about 0.5 to 1 point on a 7-point Likert scale; low to moderate quality evidence). There was no data on the effect of honey on cough duration because follow-up was for 1 day only. There was no significant difference in gastrointestinal side

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

83. Renal and ureteric stones: assessment and management

consideration of the evidence available. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service. It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances of the individual, in consultation with them and their families and carers or guardian (...) decisions about their care, as described in your care. Making decisions using NICE guidelines explains how we use words to show the strength (or certainty) of our recommendations, and has information about prescribing medicines (including off-label use), professional guidelines, standards and laws (including on consent and mental capacity), and safeguarding. 1.1 Diagnostic imaging 1.1.1 Offer urgent (within 24 hours of presentation) low-dose non-contrast CT to adults with suspected renal colic

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

84. Relationship between volumes of services and quality of treatment outcome in the surgical treatment of breast cancer - rapid report

in the analysis, that is, whenever more than 30% of patients were excluded from analysis. Results were also omitted from the investigation whenever the percentage of patients excluded from analysis differed by more than 15% between groups. If the studies’ authors used several statistical models and justified their choice of a preferred model for their underlying data, the statistical model preferred by the author team was used, provided the model fulfilled the conditions defined in Section 4.1.5. If several (...) taken into account and the sources used (administrative databases, clinical databases, medical records). Likewise, the quality of the statistical models used to examine any correlation between VoS and outcome was assessed; this quality depends on the form in which the characteristic of volume entered into the analysis (continuous versus categorical data), the consideration of cluster effects (see Section 4.1.5), and the examination of model quality [32]. The completeness of reporting (e.g

2020 Institute for Quality and Efficiency in Healthcare (IQWiG)

85. Attention deficit hyperactivity disorder: diagnosis and management

of ADHD, should be referred for assessment by a mental health specialist trained in the diagnosis and treatment of ADHD, where there is evidence of typical manifestations of ADHD (hyperactivity/impulsivity and/or inattention) that: began during childhood and have persisted throughout life are not explained by other psychiatric diagnoses (although there may be other coexisting psychiatric conditions) have resulted in or are associated with moderate or severe psychological, social and/or Attention (...) of the person's everyday life and and a full developmental and psychiatric history and and observer reports and assessment of the person's mental state. [2008] [2008] 1.3.2 A diagnosis of ADHD should not be made solely on the basis of rating scale or observational data. However, rating scales such as the Conners' rating scales and the Strengths and Difficulties Questionnaire are valuable adjuncts, and observations (for example, at school) are useful when there is doubt about symptoms. [2008] [2008] 1.3.3

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

86. Dementia: assessment, management and support for people living with dementia and their carers

living with mild to moderate dementia, unless they are indicated for a pre-existing severe mental health problem. Sleep problems Sleep problems 1.7.13 Do not offer melatonin to manage insomnia in people living with Alzheimer's disease. 1.7.14 For people living with dementia who have sleep problems, consider a personalised multicomponent sleep management approach that includes sleep hygiene education, exposure to daylight, exercise and personalised activities. P Parkinson arkinson's disease 's disease (...) our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service. It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

87. Learning disabilities and behaviour that challenges: service design and delivery

The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service. It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances (...) of skilled staff to meet people's needs. This was restated in a later review, the so-called 'Mansell 2 report' (Services for people with learning disabilities and challenging behaviour or mental health needs Department of Health), which also highlighted the increased use of placements away from people's homes. The exposure of widespread abuse at Winterbourne View hospital in 2011 led to a review of care provided in this hospital, and across England more widely, for people with a learning disability

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

88. Otitis media (acute): antimicrobial prescribing

of the evidence available. When exercising their judgement, professionals and practitioners are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or the people using their service. It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances of the individual, in consultation with them and their families and carers or guardian. Local (...) on first choice taken for at least 2 en for at least 2 to 3 to 3 da days) ys) Co-amoxiclav 1 to 11 months, 0.25 ml/kg of 125/31 suspension three times a day for 5 to 7 days 1 to 5 years, 5 ml of 125/31 suspension three times a day or 0.25 ml/kg of 125/31 suspension three times a day for 5 to 7 days 6 to 11 years, 5 ml of 250/62 suspension three times a day or 0.15 ml/kg of 250/62 suspension three times a day for 5 to 7 days 12 to 17 years, 250/125 mg or 500/125 mg three times a day for 5 to 7 days

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

89. Post-traumatic stress disorder

care, GPs should take responsibility for assessment and initial coordination of care. This includes determining the need for emergency physical or mental health assessment. [2005, amended 2018] [2005, amended 2018] 1.2.2 Assessment of people with PTSD should be comprehensive, including an assessment of physical, psychological and social needs and a risk assessment. [2005, amended 2018] [2005, amended 2018] 1.2.3 Where management is shared between primary and secondary care, healthcare professionals (...) there may be cultural challenges to recognising the psychological consequences of trauma (see recommendations on avoiding stigma and promoting social inclusion in the NICE guideline on service user experience in adult mental health). [2005, amended 2018] [2005, amended 2018] 1.5.2 Ensure that screening, assessment and interventions for PTSD are culturally and linguistically appropriate. [2005, amended 2018] [2005, amended 2018] 1.5.3 If language or culture differences present challenges to the use

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

90. Patisiran for treating hereditary transthyretin amyloidosis

the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take this guidance fully into account, alongside the individual needs, preferences and values of their patients. The application of the recommendations in this guidance are at the discretion of health professionals and their individual patients and do not override the responsibility of healthcare professionals to make decisions appropriate (...) -of-rights). Page 9 of 32provide physical and emotional care to patients while experiencing a considerable emotional burden of their own. Carers of people with hATTR amyloidosis reported that dealing with gastrointestinal problems (especially diarrhoea), patients' mental functioning and the combination of symptoms is particularly difficult. The committee concluded that hATTR amyloidosis is a rare, serious and debilitating condition that severely affects the lives of patients, families and carers. Unmet

2019 National Institute for Health and Clinical Excellence - Highly specialised technology

91. Idelalisib for treating refractory follicular lymphoma

' matching adjusted indirect comparison was 26.7 people (26.7 represents a statistic rather than an actual number of people). The committee concluded that, although it preferred the 'updated' over the 'reverse' comparison, sparse data and potential confounding meant that the clinical-effectiveness results reflecting both were unreliable. Idelalisib for treating refractory follicular lymphoma (TA604) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms (...) at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take this guidance fully into account, alongside the individual needs, preferences and values of their patients. The application of the recommendations in this guidance are at the discretion of health professionals and their individual patients and do not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

92. Transcatheter Aortic Valve Implantation in Patients With Severe, Symptomatic Aortic Valve Stenosis at Intermediate Surgical Risk

BACKGROUND 10 Health Condition 10 Clinical Need and Target Population 10 Current Treatment Options 10 Health Technology Under Review 11 Regulatory Information 12 Ontario Context 12 PROSPERO Registration 12 CLINICAL EVIDENCE 13 Research Question 13 Methods 13 Clinical Literature Search 13 Literature Screening 14 Inclusion Criteria 14 Exclusion Criteria 14 Outcomes of Interest 15 Data Extraction 15 Evidence Synthesis and Statistical Analysis 15 Critical Appraisal of Evidence 16 Expert Consultation 16 (...) . For individual studies, we extracted relevant data on study design and characteristics, risk-of- bias items, results, and PICOTS. We extracted the patients’ baseline characteristics, including those based on the PROGRESS-Plus categories (place of residence, race/ethnicity, occupation, gender/sex, religion, education, socioeconomic status, social capital), when available. 23 We contacted authors of the studies to provide clarification as needed. Evidence Synthesis and Statistical Analysis We summarized

2020 Health Quality Ontario

93. 10-kHz High-Frequency Spinal Cord Stimulation for Adults With Chronic Noncancer Pain

Ontario Context 11 Expert Consultation 12 PROSPERO Registration 12 CLINICAL EVIDENCE 13 Research Question 13 Methods 13 Clinical Literature Search 13 Eligibility Criteria 13 Literature Screening 14 Data Extraction 14 Statistical Analysis 15 Critical Appraisal of Evidence 15 Results 16 Clinical Literature Search 16 Characteristics of Included Studies 17 Risk of Bias in the Included Studies 18 Pain Intensity 19 Functional Disability 22 Opioid Use 23 Patient Satisfaction 23 Global Impression of Change 24 (...) , such as burst) Outcome Measures • Effectiveness – Pain: intensity, responders – Functional disability, physical activity, mobility, employment status – Medication use, reductions in opioid or other analgesic use – Patient satisfaction – Global Impression of Change – Sleep quality – Health-related quality of life, anxiety and depression • Safety: device/surgery-related postoperative and longer-term adverse events Literature Screening A single reviewer conducted an initial screening of titles and abstracts

2020 Health Quality Ontario

94. Suicide postvention services

Having a personal or family history of mental health or suicidal behaviour increases the risks of these problems. 5,19 People bereaved by suicide are also susceptible to physical illnesses, possibly due to the levels of stress or an unhealthy lifestyle (for example, poor diet or smoking). 19-21 Recent research has also started to shed light on the phenomenon of personal (or posttraumatic) growth in suicide bereavement. 22 This has been defined as the positive psychological changes experienced (...) INSTITUTE Study reference, Location Study design, assessment Level of evidence (NHMRC grade) Sample Intervention / control N = … Age: M (SD) or range Sex: F/M: n/n (%/%) Intervention, Setting Outcome measures Main outcomes Limitations suicide (Panta Rhei): A pilot feasibility study. Psychology and Psychotherapy, 92(1), 39-56 Italy -Baseline: 4–6 days before intervention -Post: 4–6 days after emotion- and grief-oriented exercises Setting: Residential, group Dimensions of affect: Profile of Mood States

2020 Sax Institute Evidence Check

95. Mid-life support: Insights for employers

Examples of topics Health General Overall health - past, current and future Impact on work/life Life expectancy and family history Family health/possible caring responsiblities Weight Fitness Current level of exercise Future opportunities to make changes Health behaviours including diet, alcohol consumption and smoking habits) Critical illnesses Own and family history (cancer, stroke, kidney disease, diabetes, dementia, lung disease) Help NHS Health check Emotional/ psychological Personal attributes (...) that, at least sometimes, they have too little money to spend on their needs. (Centre for Ageing Better, 2015). More than one third (35.7%) of people aged 45–54 are so-called sandwich carers (with a dependent child in their home and providing regular care to a relative who is sick, disabled or elderly (Office for National Statistics, 2019) and 55-64 is the peak age for caring in the UK (Census, 2011). There are 1.8 million low to middle income (LMI 1 ) older households in the UK, in which the head

2020 The Centre for Ageing Better

96. What research has been done to understand substance misuse within the UK student population, and what interventions have been introduced as a result?

that they currently use drugs • There was low use of, and low knowledge about, drugs such as modafinil, Ritalin or Adderall • Students mainly used drugs for recreational purposes, but other motives included enhancement for sports or academia, the ability to sleep/reduce stress, or to manage illnesses • 16% of the universities surveyed, incorrectly advised students that the use of drugs is a criminal offence • Public health policies should include social interventions aimed at generating recreational alternatives (...) smoking. Drug use “Student drug use is not homogenous and very little is known about the nuances and diversity of their use/non-use beyond prevalence data” p224 (1) a) Prevalence Over the last 10 years, there has been an increase in the amount of research on drug use among university students, but much of this has been conducted in the United States (US) (2). In 2018, a review of the literature to determine the current state of knowledge on student drug use specifically in the UK, found 13 UK studies

2020 Public Health England - Evidence Briefings

97. Raising the bar on strength and balance: The importance of community-based provision

that are most beneficial to the three population groups identified, it is useful to think about appropriate settings for delivery, workforce and qualification requirements, together with opportunities to embed messaging around strength and balance across the spectrum. Table 2 demonstrates these considerations. Type of sport, physical activity or exercise Strong e?ect Running Resistance Training Aerobics, circuit training Ball Games Racquet Sports Yoga, Tai Chi Dance Walking Nordic Walking Cycling (...) exist for outcomes relating to reducing isolation and promoting physical activity for example. Sports: swim, cycle, run, walk, group exercise, gym programmes. Programmes should include a pre-exercise assessment due to potential co-morbidities requiring liaison with GP. Participants may need to speak to their GP before participating in exercise programmes. Exercise instructors, physiotherapists, therapy teams, specialist teams. Exercise instructors, volunteers. Exercise instructors, support workers

2020 The Centre for Ageing Better

98. Axicabtagene ciloleucel for treating diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma after 2 or more systemic therapies

of the treatment. Both the clinical experts and NHS England's clinical lead for the Cancer Drugs Fund noted that patients in ZUMA-1 were representative of the various subgroups who would be eligible for axicabtagene ciloleucel in the NHS. The committee concluded that the results from ZUMA-1 were generalisable to patients in the NHS. ZUMA ZUMA-1 is a single-arm study so compar -1 is a single-arm study so comparator data need to be tak ator data need to be taken from an en from an alternativ alternative source e (...) the clinical plausibility of the extrapolated curve and the survival plateau for patients who had not had subsequent stem cell transplants. The committee noted that in the ERG's exploratory analyses, considering external (the extent to which the long-term predictions align with other data sources or clinical experience) and internal (visual assessment and goodness of fit statistics) validity, a generalised gamma distribution was considered the more appropriate choice. The committee acknowledged

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

99. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

, fatigue, myalgia, and headache, followedbymildsuppressionof bone marrow. Attention should be paid to identify the change of clinical manifestations or adverse drug reactions. 8.2.3 Nutritional support According to the patients’ condition, provide high- protein, high-vitamin, carbohydrate-containing diets (e.g. eggs, fish, lean meat, milk, etc.) for enough nu- trition to improve physical condition. 8.2.4 Psychological nursing Take good care of the patient and respond to the pa- tient’s question timely (...) management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control (including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue

2020 Covid-19 Ad hoc guidelines

100. Optimising maternity services and maternal and newborn outcomes in a pandemic A rapid analytic scoping review

the safety of community and hospital settings for health professionals? Principles for equitable, safe, effective, quality maternal and newborn care in a pandemic were developed to inform this review, derived from evidence and key resources: o Continue to provide evidence-based, equitable, safe, compassionate and respectful care for physical and mental health, wherever and whenever care takes place, by remote access if necessary o Protect the human rights of women and newborn infants, unless and only (...) unless the public health imperative makes this impossible o Ensure strict hygiene measures and social distancing when possible o Ensure birth companionship o Prevent unnecessary interventions o Do not separate mother and newborn infant unless absolutely necessary o Promote and support breastfeeding o Protect and support staff, including their mental health needs Key findings and recommendations on each review question are briefly presented, including strategies for maintaining essential components

2020 Royal College of Midwives

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