How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

70,046 results for

("critical care")

by
...
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21. Approaches to Addressing Post-Intensive Care Syndrome among Intensive Care Unit (ICU) Survivors: A Narrative Review. (Abstract)

Approaches to Addressing Post-Intensive Care Syndrome among Intensive Care Unit (ICU) Survivors: A Narrative Review. Critical illness can be lethal and devastating to survivors. Improvements in acute care have increased the number of intensive care unit (ICU) survivors. These survivors confront a range of new or worsened health states that is commonly denominated Post Intensive Care Syndrome (PICS). These problems include physical, cognitive, psychological, and existential aspects among others (...) . Burgeoning interest in improving long-term outcomes for ICU survivors has driven an array of potential interventions to improve outcomes associated with PICS. To date the most promising interventions appear to relate to very early physical rehabilitation. Late interventions within aftercare and recovery clinics have yielded mixed results, although experience from heart failure programs suggests the possibility that very early case management interventions may help improve intermediate-term outcomes

2019 Annals of the American Thoracic Society

22. The chronic ICU patient: Is intensive care worthwhile for patients with very prolonged ICU-stay (≥ 90 days)? (Abstract)

The chronic ICU patient: Is intensive care worthwhile for patients with very prolonged ICU-stay (≥ 90 days)? Due to medical advances, an increasing number of patients are surviving the acute critical illness. However, some patients require a prolonged critical care treatment. Data on outcome and functional status of patients with an ICU-stay ≥90 days are scarce.Single-center retrospective study including all adult patients with ICU stay ≥90 days treated at the department of intensive care (...) medicine at the university medical center Hamburg-Eppendorf, Germany, between January 1st 2008 and December 31st 2016.Out of 65,249 patients, we identified 96 (0.1%) patients with a very prolonged ICU stay. Median age was 61 (49.8-67) years, 30 (31%) patients were female. Patients were admitted to ICU due to abdominal (28%) reasons, followed by sepsis (23%) and transplantation (15%). Fourteen patients received organ-transplantation: 9 received liver-, 4 lung- and 1 heart-transplantation. All patients

2019 European journal of internal medicine

23. Exploring positive aspects of caregiving in family caregivers of adult icu survivors from ICU to four months post-ICU discharge. (Abstract)

Exploring positive aspects of caregiving in family caregivers of adult icu survivors from ICU to four months post-ICU discharge. Despite growing attention to the positive meaning from ICU survivorship, little is known about positive experience among family caregivers of ICU survivors.To explore positive aspects of caregiving in family caregivers from patients' ICU admission to 4-month post-ICU discharge.A secondary analysis of data from 47 family caregivers of ICU patients who self-reported (...) of ICU survivors rated their caregiving experience as positive during the ICU and post-ICU periods.Copyright © 2019 Elsevier Inc. All rights reserved.

2019 Heart & Lung

24. A Combination Antibiogram Evaluation for <i>Pseudomonas aeruginosa</i> in Respiratory and Blood Sources from Intensive Care Unit (ICU) and Non-ICU Settings in U.S. Hospitals. Full Text available with Trip Pro

A Combination Antibiogram Evaluation for Pseudomonas aeruginosa in Respiratory and Blood Sources from Intensive Care Unit (ICU) and Non-ICU Settings in U.S. Hospitals. Pseudomonas aeruginosa is an important pathogen associated with significant morbidity and mortality. U.S. guidelines for the treatment of hospital-acquired and ventilator-associated pneumonia recommend the use of two antipseudomonal drugs for high-risk patients to ensure that ≥95% of patients receive active empirical (...) not achieve the goal of 95% antibiotic coverage. Adding an aminoglycoside resulted in higher susceptibility rates than adding a fluoroquinolone; piperacillin-tazobactam plus an aminoglycoside resulted in the highest susceptibility rate (93.3%). Intensive care unit (ICU) isolates generally had lower susceptibility rates than non-ICU isolates. Commonly used antipseudomonal drugs, either alone or in combination, did not achieve 95% coverage against U.S. hospital P.aeruginosa isolates, suggesting that new

2019 Antimicrobial Agents and Chemotherapy

25. International prospective observational study on intracranial pressure in intensive care (ICU): the SYNAPSE-ICU study protocol. Full Text available with Trip Pro

International prospective observational study on intracranial pressure in intensive care (ICU): the SYNAPSE-ICU study protocol. Intracranial pressure (ICP) monitoring is commonly used in neurocritical care patients with acute brain injury (ABI). Practice about indications and use of ICP monitoring in patients with ABI remains, however, highly variable in high-income countries, while data on ICP monitoring in low and middle-income countries are scarce or inconsistent. The aim of the SYNAPSE-ICU (...) available to the scientific community by means of abstracts submitted to the European Society of Intensive Care Medicine annual conference and by scientific reports and original articles submitted to peer-reviewed journals.NCT03257904.© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

2019 BMJ open

26. Clinical practice guidelines for pain, agitation, delirium, sedation and mobilisation in the intensive care unit: A Rapid Review

Clinical practice guidelines for pain, agitation, delirium, sedation and mobilisation in the intensive care unit: A Rapid Review ICU pain, agitation, delirium, sedation and mobilisation CPGs: A Rapid Review 1 Clinical practice guidelines for pain, agitation, delirium, sedation and mobilisation in the intensive care unit: A Rapid Review Citation Corey Joseph & Angela Melder. April 2018. Clinical practice guidelines for pain, agitation, delirium, sedation and mobilisation in the intensive care (...) unit: A Rapid Review. Centre for Clinical Effectiveness, Monash Health, Melbourne, Australia. Contact cce@monashhealth.org Executive Summary Background The Program Medical Director for Critical Care has requested a review of clinical practice guidelines for pain, agitation, delirium, sedation and mobilisation in the intensive care unit (ICU) to inform future implementation of a new clinical practice guideline in the ICU. Objectives The objective of this review was to review and summarise current

2019 Monash Health Evidence Reviews

27. Nutrition Therapy in the Patient with COVID-19 Disease Requiring ICU Care

and Enteral Nutrition Intensive care units (ICU) worldwide have become overwhelmed with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced respiratory failure leading to COVID-19 disease. Good supportive care remains the cornerstone in managing critically ill patients with COVID-19. The need to address the provision of critical care nutrition remains an integral component of these supportive measures. The nutritional management of the ICU patient with COVID-19 is in principle very (...) , Desachy A, Bellec F, et al.; Clinical Research in Intensive Care and Sepsis (CRICS) Group. Effect of not monitoring residual gastric volume on Nutrition Therapy in the Patient with COVID-19 Disease Requiring ICU Care: Updated March 30, 2020 8 risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a randomized controlled trial. JAMA. 2013 Jan 16;309(3):249-56. 12. Reignier J, Dimet J, Martin-Lefevre L, Bontemps F, Fiancette M, Clementi E,et

2020 American Society for Parenteral and Enteral Nutrition

28. APSF/ASA Guidance on Purposing Anesthesia Machines as ICU Ventilators

patients. Anesthesia machines require more monitoring than do ICU ventilators and room access for non- COVID patients is easier. 4. WHERE SHOULD THE MACHINES BE USED? OR or ICU? (UPDATED APRIL 7, 2020) Ongoing ICU level patient care is best done in an intensive care unit but the local resources will likely dictate where the anesthesia machines will be deployed. a. ICU Rooms: At a minimum, the room requires space to accommodate the machine and sources of high pressure air and oxygen. Scavenging (...) APSF/ASA Guidance on Purposing Anesthesia Machines as ICU Ventilators APSF/ASA Guidance on Purposing Anesthesia Machines as ICU Ventilators Anesthesia machines are equipped with ventilators that in many cases are capable of providing life-sustaining mechanical ventilation to patients with respiratory failure. They are used for this purpose every day in the operating room. FDA approved labeling does not provide for using anesthesia ventilators for long term ventilatory support. Nevertheless

2020 American Society of Anesthesiologists

29. Evidence summary for average length of stay in the intensive care unit for COVID-19

in the intensive care unit for COVID-19 The Health Information and Quality Authority (HIQA) has developed a series of ‘Evidence Summaries’ to assist the Clinical Expert Advisory Group (EAG) supporting the National Public Health Emergency Team (NPHET) in their response to COVID-19. These summaries are based on specific research questions. This evidence summary was developed to address the following research question: What is the average or median length of stay in the intensive care unit (ICU) for affected (...) admitted to ICU, in Wuhan, China with a definitive outcome (discharge or death) up to 31 January 2020. The second study (2) reports a retrospective analysis of 101 deceased patients in one intensive care unit in Wuhan, China up to 16 February 2020. The third study describes the first 18 cases of COVID-19 identified in Singapore, of which two patients were admitted to ICU. The fourth study describes the first 12 cases of COVID-19 identified in the United States, of which one received ICU level of care

2020 Health Information and Quality Authority

30. Pediatric Hyperinflammatory Syndrome and COVID-19: Statement and Recommendations From a Pediatric Intensive Care International Collaborative Conference Call

Pediatric Hyperinflammatory Syndrome and COVID-19: Statement and Recommendations From a Pediatric Intensive Care International Collaborative Conference Call Pediatric Hyperinflammatory Syndrome and COVID-19: Statement and Recommendations From a Pediatric Intensive Care International Collaborative Conference Call - American College of Cardiology ') Search All Types Search or Menu put forth by the Royal College of Pediatrics and Child Health (see sidebar on right). Children with SARS-CoV-2 (...) benefit from care by a multidisciplinary team of specialists, including those with expertise in intensive care, cardiology, rheumatology, immunology and infectious diseases. Royal College of Pediatrics and Child Health Case Definition for Paediatric multisystem inflammatory syndrome temporally associated with COVID-19 A child presenting with persistent fever, inflammation (neutrophilia, elevated CRP and lymphopenia) and evidence of single or multiorgan dysfunction (shock, cardiac, respiratory, renal

2020 American College of Cardiology

31. Antibiotic Stewardship in the Intensive Care Unit: An Official ATS Workshop Report in Collaboration with the ACCN, ACCP, CDC, and SCCM Full Text available with Trip Pro

and Prevention, American Association of Critical-Care Nurses, American College of Chest Physicians, and Society of Critical Care Medicine Show All... PubMed: You may print one copy of this document at no charge. However, if you require more than one copy, you must place a reprint order. Domestic reprint orders: ; international reprint orders: . Abstract Section: Intensive care units (ICUs) are an appropriate focus of antibiotic stewardship program efforts because a large proportion of any hospital’s use (...) -Resistant Bacteria initiative is the enhancement of antibiotic stewardship programs (ASPs) to preserve the activity of current and future antibiotics ( ). Intensive care units (ICUs) are an appropriate focus of ASP efforts because a large proportion of any hospital’s use of parenteral antibiotics, especially broad-spectrum, occurs in the ICU ( ). The ICU is also the locus of many patients with life-threatening infections due to multidrug-resistant (MDR) bacteria ( ). However, despite general support

2020 American Thoracic Society

32. Assessment of Costs of Avoidable Delays in Intensive Care Unit Discharge Full Text available with Trip Pro

Assessment of Costs of Avoidable Delays in Intensive Care Unit Discharge Assessment of Costs of Avoidable Delays in Intensive Care Unit Discharge | Critical Care Medicine | JAMA Network Open | JAMA Network Publications | | 2020 American Medical Association. All Rights Reserved Individual Sign In Institutional Sign In Figure 1. Patient Selection Flowchart ICU indicates intensive care unit. Figure 2. Monthly Mean Avoidable Time During the Study Period Table 1. Basic Characteristics of the Study (...) study.  JAMA Intern Med . 2018;178(10):1390-1399. doi:  Martin CM, Lam M, Allen B, et al. Determinants of direct discharge home from critical care units: a population-based cohort analysis.  Crit Care Med . 2020;48(4):475-483. doi:  Rewa OG, Stelfox HT, Ingolfsson A, et al. Indicators of intensive care unit capacity strain: a systematic review.  Crit Care . 2018;22(1):86. doi:  Tran DT, Thanh NX, Opgenorth D, et al. Association between strained ICU capacity and healthcare costs

2020 Institute of Health Economics

33. Dutch ICU survivors have more consultations with general practitioners before and after ICU admission compared to a matched control group from the general population. Full Text available with Trip Pro

Dutch ICU survivors have more consultations with general practitioners before and after ICU admission compared to a matched control group from the general population. General Practitioners (GPs) play a key role in the healthcare trajectory of patients. If the patient experiences problems that are typically non-life-threatening, such as the symptoms of post-intensive-care syndrome, the GP will be the first healthcare professional they consult. The primary aim of this study is to gain insight (...) in the frequency of GP consultations during the year before hospital admission and the year after discharge for ICU survivors and a matched control group from the general population. The secondary aim of this study is to gain insight into differences between subgroups of the ICU population with respect to the frequency of GP consultations.We conducted a retrospective cohort study, combining a national health insurance claims database and a national quality registry for ICUs. Clinical data of patients admitted

2019 PLoS ONE

34. Evaluation of ICU Risk Models Adapted for Use as Continuous Markers of Severity of Illness Throughout the ICU Stay (Abstract)

Evaluation of ICU Risk Models Adapted for Use as Continuous Markers of Severity of Illness Throughout the ICU Stay Evaluate the accuracy of different ICU risk models repurposed as continuous markers of severity of illness.Nonintervention cohort study.eICU Research Institute ICUs using tele-ICU software calculating continuous ICU Discharge Readiness Scores between January 2013 and March 2016.Five hundred sixty-one thousand four hundred seventy-eight adult ICU patients with an ICU length of stay (...) between 4 hours and 30 days.Not available.Hourly Acute Physiology and Chronic Health Evaluation IV, Sequential Organ Failure Assessment, and Discharge Readiness Scores were calculated beginning hour 4 of the ICU stay. Primary outcome was the area under the receiver operating characteristic curve for the mean score with ICU mortality. Secondary outcomes included area under the receiver operating characteristic curves for ICU mortality with admission, median, maximum and last scores, and for death

2018 EvidenceUpdates

35. Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial. Full Text available with Trip Pro

Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial. Acute acidaemia is frequently observed during critical illness. Sodium bicarbonate infusion for the treatment of severe metabolic acidaemia is a possible treatment option but remains controversial, as no studies to date have examined its effect on clinical outcomes. Therefore, we aimed to evaluate whether sodium (...) bicarbonate infusion would improve these outcomes in critically ill patients.We did a multicentre, open-label, randomised controlled, phase 3 trial. Local investigators screened eligible patients from 26 intensive care units (ICUs) in France. We included adult patients (aged ≥18 years) who were admitted within 48 h to the ICU with severe acidaemia (pH ≤7·20, PaCO2 ≤45 mm Hg, and sodium bicarbonate concentration ≤20 mmol/L) and with a total Sequential Organ Failure Assessment score of 4 or more

2018 Lancet

36. Consensus guidelines for managing the airway in patients with COVID-19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetist Full Text available with Trip Pro

Consensus guidelines for managing the airway in patients with COVID-19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetist Severe acute respiratory syndrome-corona virus-2, which causes coronavirus disease 2019 (COVID-19), is highly contagious. Airway management of patients with COVID-19 is high risk to staff and patients. We aimed to develop principles for airway

2020 Anaesthesia

37. Potential preventive and therapeutic effect of Chinese herb rhubarb (da huang) for intensive care unit/pediatric intensive care unit gastrointestinal failure patients: A protocol for systematic review. Full Text available with Trip Pro

Potential preventive and therapeutic effect of Chinese herb rhubarb (da huang) for intensive care unit/pediatric intensive care unit gastrointestinal failure patients: A protocol for systematic review. The Chinese herb da huang (DH) (Rhubarb) is commonly used for GIF intensive care unit (ICU)/pediatric intensive care unit (PICU) gastrointestinal failure (GIF) patients in China. However, the potential preventive and therapeutic effect of DH in these patients has not yet been studied (...) systematically.The aim of this study was to evaluate the preventive and therapeutic effects of DH in treating ICU/PICU GIF patients with the most recent evidence.We systematically searched 7 databases from inception to March 30, 2018. RevMan 5.3 software was used to perform a meta-analysis. GRADE methodology was applied to evaluate the quality of evidence for each outcome. The review protocol was registered on PROSPERO (CRD42018092710) in advance.Seven studies comprising 788 pediatric or adult participants were

2020 Medicine

38. Is my patient ready for a safe transfer to a lower-intensity care setting? Nursing complexity as an independent predictor of adverse events risk after ICU discharge. (Abstract)

Is my patient ready for a safe transfer to a lower-intensity care setting? Nursing complexity as an independent predictor of adverse events risk after ICU discharge. Patients discharged from intensive care units (ICUs) are at risk for adverse events (AEs). Establishing safe discharge criteria is challenging. No available criteria consider nursing complexity among risk factors.To investigate whether nursing complexity upon ICU discharge is an independent predictor for AEs.Prospective (...) observational study. The Patient Acuity and Complexity Score (PACS) was developed to measure nursing complexity. Its predictive power for AEs was tested using multivariate regression analysis.The final regression model showed a very-good discrimination power (AUC 0.881; p<0.001) for identifying patients who experienced AEs. Age, ICU admission reason, PACS, cough strength, PaCO2, serum creatinine and sodium, and transfer to Internal Medicine showed to be predictive of AEs. Exceeding the identified PACS

2020 Heart & Lung

39. The handling oxygenation targets in the intensive care unit (HOT-ICU) trial: Detailed statistical analysis plan. (Abstract)

The handling oxygenation targets in the intensive care unit (HOT-ICU) trial: Detailed statistical analysis plan. No solid evidence exists on optimal oxygenation targets in intensive care patients. The handling oxygenation targets in the intensive care unit (HOT-ICU) trial assesses the effects of a targeted arterial oxygen tension of 8 vs 12 kPa on 90-day mortality in acutely admitted adult patients with hypoxaemic respiratory failure. This article describes the detailed statistical analysis (...) plan for the predefined outcomes and supplementary analyses in the HOT-ICU trial.The trial will include 2928 patients to be able to detect or reject a true 20% relative risk reduction in the primary outcome of 90-day all-cause mortality with an α of 5% and a β of 10%. Analyses of the primary and secondary outcomes will be conducted according to the intention-to-treat principle and adjusted for stratification variables. The primary outcome and dichotomous secondary outcomes will be analysed using

2020 Acta Anaesthesiologica Scandinavica

40. The Agents Intervening against Delirium in the Intensive Care Unit-Trial (AID-ICU trial):- a detailed statistical analysis plan. (Abstract)

The Agents Intervening against Delirium in the Intensive Care Unit-Trial (AID-ICU trial):- a detailed statistical analysis plan. The AID-ICU trial aims to assess the benefits and harms of haloperidol for the treatment of delirium in acutely admitted, adult intensive care unit (ICU) patients. This paper describes the detailed statistical analysis plan for the primary publication of results from the AID-ICU trial.The AID-ICU trial is a investigator-initiated, pragmatic, international, multicentre (...) , randomised, blinded, parallel-group trial allocating 1000 adult ICU patients with manifest delirium 1:1 to haloperidol or placebo. The primary outcome measure is days alive and out of hospital within 90 days post-randomisation. Secondary outcome measures are days alive without delirium or coma, Serious Adverse Reactions (SARs) to haloperidol, use of escape medicine, days alive without mechanical ventilation, and mortality, health-related quality-of-life measures and cognitive function 1-year post

2020 Acta Anaesthesiologica Scandinavica

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>