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1. Surveillance of healthcare-associated infections and prevention indicators in European intensive care units: HAI-Net ICU protocol, version 2.2

Surveillance of healthcare-associated infections and prevention indicators in European intensive care units: HAI-Net ICU protocol, version 2.2 TECHNICAL DOCUMENT www.ecdc.europa.eu Surveillance of healthcare-associated infections and prevention indicators in European intensive care units HAI-Net ICU protocol, version 2.2ECDC TECHNICAL DOCUMENT Surveillance of healthcare-associated infections and prevention indicators in European intensive care units HAI-Net ICU protocol, version 2.2 ii (...) members shall not, in the performance of their duties, deal with a matter in which, directly or indirectly, they have any personal interest such as to impair their independence. Acknowledgements ECDC would like to thank the HAI-Net ICU operational contact points and Member States experts for providing input during meetings (October 2013, February 2014, February 2015), as well as the European Society of Intensive Care Medicine (Infection Section) for reviewing and commenting on the structure

2017 European Centre for Disease Prevention and Control - Technical Guidance

2. AnaConDa-S for sedation with volatile anaesthetics in intensive care

. • SED001: a randomised, controlled, open-label study to confirm the efficacy and safety of sedation with isoflurane in invasively ventilated ICU patients using the AnaConDa administration system. EudraCT number: 2016-004551-67. Status: completed, awaiting publication. Indication: patients in intensive care. Devices: isoflurane or propofol. Date: February 2020. Country: Germany. • SEVO-COVID19: sedation with sevoflurane versus propofol in patients with acute respiratory distress syndrome caused by COVID (...) AnaConDa-S for sedation with volatile anaesthetics in intensive care AnaConDa-S for sedation with volatile anaesthetics in intensive care Medtech innovation briefing Published: 6 October 2020 www.nice.org.uk/guidance/mib229 pathways Summary Summary • The technology technology described in this briefing is AnaConDa-S. It is a volatile anaesthetic delivery system for use with ventilators to allow people to be sedated using inhaled anaesthetics (isoflurane or sevoflurane). • The innovative aspects

2020 National Institute for Health and Clinical Excellence - Advice

3. Clinical Frailty Scale in prediction of mortality, disability and quality of life for patients in need of intensive care

. “Critical Illness”[Mesh] 27 989 4. critical care[Title/Abstract] 29 925 5. Critical illness[Title/Abstract] 8 819 6. critically ill[Title/Abstract] 43 135 7. Intensive care[Title/Abstract] 140 634 8, ICU[Title/Abstract] 54 277 9. 1-8 (OR) 248 489 10 “Airway Management”[Mesh] 133 633 11. “Respiratory Insufficiency”[Mesh] 63 557 12. Influenza, Human[Mesh] 48 335 13. Pneumonia[Mesh] 90 785 14. Ventilat*[Title/Abstract] 162 458 15. Respirat*[Title/Abstract] 485 671 16. Airway*[Title/Abstract] 159 850 17 (...) ; ’ ’ = Citation Marks; searches for an exact phrase Search terms Items found Population: 1. ‘intensive care’/exp 699 967 2. ‘intensive care unit’/exp 186 548 3. ‘critical illness’/exp 28 616 4. ‘critically ill patient’/exp 42 781 5. ‘critical care’:ti,ab,kw 45 100 6. ‘critical illness’:ti,ab,kw 11 979 7. ‘critically ill’:ti,ab,kw 63 867 8. ‘intensive care’:ti,ab,kw 202 584 9. ‘icu’:ti,ab,kw 111 350 10. 1-9 (OR) 916 778 11. ‘assisted ventilation’/exp 168 620 12. ‘respiratory failure’/exp 101 148 13. ‘virus

2020 Swedish Council on Technology Assessement

4. Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants. (Abstract)

Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants. Infants in the neonatal intensive care unit (NICU) are subjected to stress, including sound of high intensity. The sound environment in the NICU is louder than most home or office environments and contains disturbing noises of short duration and at irregular intervals. There are competing auditory signals that frequently challenge preterm infants, staff and parents. The sound levels (...) . To evaluate the effects of sound reduction on short-term medical outcomes (bronchopulmonary dysplasia, intraventricular haemorrhage, periventricular leukomalacia, retinopathy of prematurity). 2. To evaluate the effects of sound reduction on sleep patterns at three months of age. 3. To evaluate the effects of sound reduction on staff performance. 4. To evaluate the effects of sound reduction in the neonatal intensive care unit (NICU) on parents' satisfaction with the care.We searched the Cochrane Central

2020 Cochrane

5. Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit. (Abstract)

or benzodiazepines) in any healthcare settings other than intensive care units (ICU).We searched ALOIS: the Cochrane Dementia and Cognitive Improvement Group's Specialized Register up to 10 April 2019. ALOIS contains records of clinical trials identified from monthly searches of a number of major healthcare databases (including MEDLINE, Embase, PsycINFO, CINAHL, LILACS), numerous trial registries (including national, international and pharmaceutical registries), and grey literature sources.We included randomised (...) Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit. Delirium is a very common condition associated with significant morbidity, mortality, and costs. Current critical care guidelines recommend first and foremost the use of nonpharmacological strategies in both the prevention and treatment of delirium. Pharmacological interventions may augment these approaches and they are currently used widely in clinical practice to manage

2020 Cochrane

6. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome: a rapid review

confirming that the excess deaths seen in the conservative oxygen group were related to differences in oxygenation. The large ICU‐ROX study, which randomized 1000 patients receiving mechanical ventilation in the intensive care unit to either a conservative or usual oxygen therapy, also included a very large prespecified subgroup of participants with a PF ratio < 300 mmHg. Although these participants were not specified as having a diagnosis of ARDS in the ICU‐ROX trial, it is likely that many participants (...) ) that were not eligible for inclusion in this review due to including patients receiving other methods of oxygen administration to mechanical ventilation. The handling oxygenation targets in the intensive care unit (HOT‐ICU) trial is randomizing patients with acute respiratory failure to receive oxygen to target a PaO 2 of either 8 kPa (60 mmHg) or 12 kPa (90 mmHg) ( ), and the second trial is investigating the effects of administering lower amounts of oxygen in patients with COVID‐19 infection

2020 Cochrane

7. ICU mortality following ICU-acquired primary bloodstream infections according to the type of pathogen: A prospective cohort study in 937 Germany ICUs (2006-2015). Full Text available with Trip Pro

ICU mortality following ICU-acquired primary bloodstream infections according to the type of pathogen: A prospective cohort study in 937 Germany ICUs (2006-2015). Mortality due to intensive care unit (ICU) acquired primary blood stream infections (PBSI) is related primarily to patient co-morbidities, types of pathogens and quality of care. The objective of this study is to determine the impact of various types of pathogen on ICU mortality.Data from the German National Nosocomial Infection (...) the prognosis after receiving the microbiological results and may therefore be useful for intensive care physicians.

2018 PLoS ONE

8. Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic

Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic COVID-19: Guidance for the remobilisation of services within health and care settings Infection prevention and control recommendations Uncontrolled if printed. COVID-19: infection prevention and control guidance About this guidance The guidance is issued jointly by the Department of Health and Social Care (DHSC), Public Health Wales (PHW), Public Health Agency (PHA) Northern Ireland, Health

2020 ICM Anaesthesia COVID-19

9. Developing an intervention around referral and admissions to intensive care: a mixed-methods study Full Text available with Trip Pro

Developing an intervention around referral and admissions to intensive care: a mixed-methods study Developing an intervention around referral and admissions to intensive care: a mixed-methods study Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need (...) . >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} This study highlighted the complexity of professional and patient communication in decision-making around referral and admissions to intensive care, with a decision support intervention showing some improved communication with patients. {{author}} {{($index , , , , , , , , , , , , , , , , , , , , & . Chris Bassford 1, 2, * , Frances Griffiths 1 , Mia Svantesson 3 , Mandy Ryan 4 , Nicolas Krucien 4 , Jeremy

2019 NIHR HTA programme

10. Assessing whether COVID-19 patients will benefit from critical care, and an objective approach to capacity challenges during a pandemic: An Intensive Care Society clinical guideline Full Text available with Trip Pro

Assessing whether COVID-19 patients will benefit from critical care, and an objective approach to capacity challenges during a pandemic: An Intensive Care Society clinical guideline Assessing whether COVID-19 patients will benefit from critical care, and an objective approach to capacity challenges during a pandemic: An Intensive Care Society clinical guideline - J Montgomery, HJ Stokes-Lampard, MD Griffiths, D Gardiner, D Harvey, G Suntharalingam, 2020 Intended for healthcare professionals (...) Alerts You are adding the following journals to your email alerts Journal New Content Announcements Journal of the Intensive Care Society Article Menu Did you struggle to get access to this article? This product could help you Accessing resources off campus can be a challenge. Lean Library can solve it Content List Citation Tools How to cite this article If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your

2020 ICM Anaesthesia COVID-19

11. COVID-19 pandemic personal protective equipment (PPE): Guidance for intensive care

be reasonably relaxed in such circumstances Page 10 of 20 ICU preparedness for the prevention and control of COVID-19 infection To deliver Critical Care through different phases of pandemic, local ICU escalation policies should: • identify the location of areas • identify the number of beds • identify the IPC measured required at each step of ICU escalation for patients with proven or highly suspected COVID-19 Intensive care services have developed plans and processes for dealing with patients with both (...) COVID-19 pandemic personal protective equipment (PPE): Guidance for intensive care COVID-19 pandemic personal protective equipment (PPE): Guidance for intensive care. IPS update: August 2020 First release: July 2020 Page 1 of 20 Endorsing organisations Page 2 of 20 COVID-19 pandemic personal protective equipment (PPE): Guidance for intensive care. Contents Endorsing organisations 1 Contents 2 List of contributors 3 Summary 4 Summary of PPE guidance 5 Suspected or proven COVID -19 6 COVID-19

2020 ICM Anaesthesia COVID-19

12. Post-ICU Syndrome: The Coming Wave That Needs Attention Now

discharged COVID-19 ICU survivors Each evening, television newscasts feature uplifting human interest stories of victory over the virus with the discharge of a patient wheeled down a hallway to greet loved ones. Dedicated caregivers clap to celebrate the challenging cases that triumphed over COVID-19. As joyful as each discharge is, weeks or months later, many survivors will say their battle was far from over. A likely postsurvival crisis: Post-intensive care syndrome (PICS) PICS, a nonspecific syndrome (...) that results from physical, mental, and emotional stresses associated with critical illness and treatment in intensive care units (ICUs), isn’t new. It was first recognized as a distinct medical entity over the past decade, and PICS awareness remains fragmentary. Because of the long ICU stays and mechanical ventilation that some patients with COVID-19 experience, PICS is likely to become much more prevalent. Cardinal features include neuromuscular weakness from immobility, cognitive impairment from

2020 Covid-19 Ad hoc papers

13. Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic

trade union and/or staff representative. There is some further guidance available from the BMA, RCM and Maternity Action. Some working environments (e.g. operating theatres, respiratory wards and intensive care/high dependency units) carry a higher risk of exposure to the virus for all healthcare staff, including pregnant women, through the greater number of aerosol-generating procedures (AGPs) performed. These procedures are summarised in the PHE publication ‘Guidance on Infection Prevention (...) Advice for pregnant members of the anaesthesia and intensive care workforce during the COVID-19 pandemic 1 Occupational health advice for employers and pregnant women during the COVID-19 pandemic Version 3: Published Tuesday 21 April 2020 COVID-19 virus infection and pregnancy2 Updates Please note that version 1 of this occupational health guidance was published as a chapter in the RCOG’s general Coronavirus (COVID-19) Infection in Pregnancy guidance. The occupational health guidance will now

2020 ICM Anaesthesia COVID-19

14. Clinical guide for acute kidney injury in hospitalised patients with COVID-19 outside the intensive care unit during the coronavirus pandemic

circumstances we may face: www.gmc- uk.org/news/news-archive/how-we-will-continue-to-regulate-in-light-of-novel-coronavirus Who is this guide for? This guidance is for use by all professionals looking after inpatients with COVID-19 outside intensive care settings. Background • Acute kidney injury (AKI) in critically ill patients is multifactorial. • There is little reliable UK data on the incidence and outcomes of patients with COVID-19 and AKI outside the ICU. • At this stage we do not have a full (...) Clinical guide for acute kidney injury in hospitalised patients with COVID-19 outside the intensive care unit during the coronavirus pandemic Publications approval reference: 001559 NHS England and NHS Improvement Specialty guides for patient management during the coronavirus pandemic Clinical guide for acute kidney injury in hospitalised patients with COVID-19 outside the intensive care unit during the coronavirus pandemic 21 April 2020, Version 1.1 (the updates in this document are marked

2020 Covid-19 Ad hoc guidelines

15. The Australian and New Zealand Intensive Care Society (ANZICS) COVID-19 Guidelines

to): ? Complex Care Units or other High Dependency Units ? Perioperative monitoring / recovery areas ? Coronary care units ? Uncommissioned or unstaffed ICU bays ? Decommissioned critical care areas (e.g. ‘old’ ICUs) The following criteria are the College of Intensive Care Medicine (CICM) requirements for a high dependency area and may be considered in repurposing an area for the care of critically ill patients: ? Two oxygen outlets ? One air outlet ? Two suction outlets ? Twelve mains electricity outlets (...) decision making is currently lacking in many areas. However, we have drawn on previous pandemic experience and contemporary infection control literature in the Intensive Care Unit (ICU). We have developed a ‘living document’, which will be revised in an iterative process that will incorporate local and international knowledge as this disease progresses through the community. The most up to date document and all previous iterations will be found on the ANZICS website www.anzics.com.au. As of today (16

2020 Covid-19 Ad hoc guidelines

16. Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT Full Text available with Trip Pro

Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website

2019 NIHR HTA programme

17. Effect of Flexible Family Visitation on Delirium Among Patients in the Intensive Care Unit: The ICU Visits Randomized Clinical Trial. Full Text available with Trip Pro

Effect of Flexible Family Visitation on Delirium Among Patients in the Intensive Care Unit: The ICU Visits Randomized Clinical Trial. The effects of intensive care unit (ICU) visiting hours remain uncertain.To determine whether a flexible family visitation policy in the ICU reduces the incidence of delirium.Cluster-crossover randomized clinical trial involving patients, family members, and clinicians from 36 adult ICUs with restricted visiting hours (<4.5 hours per day) in Brazil. Participants (...) were recruited from April 2017 to June 2018, with follow-up until July 2018.Flexible visitation (up to 12 hours per day) supported by family education (n = 837 patients, 652 family members, and 435 clinicians) or usual restricted visitation (median, 1.5 hours per day; n = 848 patients, 643 family members, and 391 clinicians). Nineteen ICUs started with flexible visitation, and 17 started with restricted visitation.Primary outcome was incidence of delirium during ICU stay, assessed using the CAM-ICU

2019 JAMA Controlled trial quality: predicted high

18. External Validation of Two Models to Predict Delirium in Critically Ill Adults Using Either the Confusion Assessment Method-ICU or the Intensive Care Delirium Screening Checklist for Delirium Assessment Full Text available with Trip Pro

External Validation of Two Models to Predict Delirium in Critically Ill Adults Using Either the Confusion Assessment Method-ICU or the Intensive Care Delirium Screening Checklist for Delirium Assessment To externally validate two delirium prediction models (early prediction model for ICU delirium and recalibrated prediction model for ICU delirium) using either the Confusion Assessment Method-ICU or the Intensive Care Delirium Screening Checklist for delirium assessment.Prospective (...) Care Delirium Screening Checklist. Discrimination was determined using the area under the receiver operating characteristic curve. The predictive performance was determined for the Confusion Assessment Method-ICU and Intensive Care Delirium Screening Checklist cohort, and compared with both prediction models' original reported performance. A total of 1,286 Confusion Assessment Method-ICU-assessed patients and 892 Intensive Care Delirium Screening Checklist-assessed patients were included. Compared

2019 EvidenceUpdates

19. Evaluating service development in critical care: The impact of establishing a medical high dependency unit on intensive care unit workload, case mix, and mortality Full Text available with Trip Pro

Evaluating service development in critical care: The impact of establishing a medical high dependency unit on intensive care unit workload, case mix, and mortality Critical care services underpin the delivery of many types of secondary care, and there is increasing focus on how to best deliver such services. The aim of this study was to investigate the impact of establishing a medical high dependency unit, in a tertiary referral center, on the workload, case mix, and mortality of the intensive (...) care unit.Single-center, 11-year retrospective study of patients admitted to the general intensive care unit, before and after the opening of the medical high dependency unit, using interrupted time series methodology.Over the duration of the study period, 3209 medical patients were admitted to the intensive care unit. There was a constant rate of medical admissions to the intensive care unit until the opening of the medical high dependency unit, followed by a statistically significant decline

2018 Journal of the Intensive Care Society

20. Report on Post-intensive Care Syndrome (PICS) for general practitioners

? TABLE OF CONTENTS LIST OF FIGURES 6 LIST OF TABLES 6 LIST OF ABBREVIATIONS 7 INTRODUCTION 9 POST-INTENSIVE CARE SYNDROME 9 PICS AND COVID-19 10 PICS AND GENERAL PRACTITIONERS 10 STUDY OBJECTIVE AND RESEARCH QUESTIONS 11 GENERAL METHODOLOGY 11 CONTENT OF THE REPORT 12 1 CHAPTER 1: WHAT IS THE POST-INTENSIVE CARE SYNDROME? 13 1.1 ICU-ACQUIRED WEAKNESS 13 1.2 MENTAL HEALTH PROBLEMS 14 1.2.1 Anxiety and depression 14 1.2.2 PTSD 14 1.3 COGNITIVE IMPAIRMENT 15 1.4 CONSEQUENCES ON FAMILY MEMBERS 16 1.5 (...) -intensive care syndrome (PICS) conceptual diagram (Needham et al) 1 9 Figure 1 – ICU discharge instrument proposed by Milton et al (online) 108 25 Figure 3 – Overview of detection tools per health domain 29 LIST OF TABLES Table 2 – Description of systematic reviews on prevalence of PICS-related disorders 18 Table 3 – Summary of risk factors identified in selected systematic reviews, per disorder 20 Table 4 – Description of findings of systematic reviews on risk factors, per dimension 22 Table 5

2020 Belgian Health Care Knowledge Centre

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