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121. Effectiveness of Interventions for Reducing Screen Time in Children

Effectiveness of Interventions for Reducing Screen Time in Children Effectiveness of Interventions for Reducing Screen Time in Children: Rapid Review of the Evidence Marco Ghassemi, Research and Policy Analyst Cathy Granger, Acting Director Chronic Disease and Injury Prevention Region of Peel Public Health October 2012 Reducing Screen Time in Children: Review of the Evidence Table of Contents Key Messages 2 Executive Summary 3 1 Issue 5 2 Context 6 3 Searching the Evidence 8 4 Critical (...) Appraisal 10 5 Description of Included Studies 10 6 Synthesis of Findings 13 7 Applicability and Transferability 20 8 Recommendations 24 References 25 Appendices 27 Appendix A: Socio-Ecological Model of Screen Time and Health 28 Appendix B: Search Strategy 29 Appendix C: Literature Search Flowchart 31 Appendix D: Data Extraction Table of Review Articles 32 Appendix E: Data Extraction Table of Primary Study Results 40 Appendix F: Data Extraction Table of Excluded Systematic Reviews 44 Appendix G

2012 Peel Health Library

122. Community-based evaluation of immigrant tuberculosis screening using interferon release assays and tuberculin skin testing: observational study and economic analysis

Community-based evaluation of immigrant tuberculosis screening using interferon release assays and tuberculin skin testing: observational study and economic analysis Community-based evaluation of immigrant tuberculosis screening using interferon release assays and tuberculin skin testing: observational study and economic analysis Community-based evaluation of immigrant tuberculosis screening using interferon release assays and tuberculin skin testing: observational study and economic analysis (...) assumptions/parameters. Bibliographic details Pareek M, Bond M, Shorey J, Seneviratne S, Guy M, White P, Lalvani A, Kon OM. Community-based evaluation of immigrant tuberculosis screening using interferon release assays and tuberculin skin testing: observational study and economic analysis. Thorax 2013; 68(3): 230-239 PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Adolescent; Adult; Asia /ethnology; Cost-Benefit Analysis; Emigration and Immigration; Female; Great

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2013 NHS Economic Evaluation Database.

123. Rapid review of factors associated with flexible sigmoidoscopy screening use. (PubMed)

Rapid review of factors associated with flexible sigmoidoscopy screening use. Flexible sigmoidoscopy (FS) screening has been shown to reduce colorectal cancer (CRC) incidence and mortality among screened adults. The aim of this review was to identify patient-related factors associated with the screening test's use. We searched PubMed for studies that examined the association between FS screening use and one or more factors. To determine the eligibility of studies, we first reviewed titles (...) , then abstracts, and finally the full paper. We started with a narrow search, which we expanded successively (by adding 'OR' terms) until the number of new publications eligible after abstract review was <1% of the total number of publications. We then abstracted factors from eligible papers and reported the number of times each was found to be positively or negatively associated with FS screening use. We identified 42 papers, most of which reported studies conducted in the United States of America (n = 21

2018 Preventive Medicine

124. A latent growth curve model to estimate electronic screen use patterns amongst adolescents aged 10 to 17 years. (PubMed)

in Grade 5 (n = 636), Grade 7 (n = 672), and Grade 9 (n = 640) for 24 months. At approximately six-month intervals, students reported their total screen time as well as time spent on social networking, passive screen use, gaming, and web use. Patterns of screen use were determined using latent growth curve modelling.In the Grades 7 and 9 cohorts, girls generally reported more screen use than boys (by approximately one hour a day), though all cohorts of boys reported more gaming. The different forms (...) A latent growth curve model to estimate electronic screen use patterns amongst adolescents aged 10 to 17 years. High quality, longitudinal data describing young people's screen use across a number of distinct forms of screen activity is missing from the literature. This study tracked multiple screen use activities (passive screen use, gaming, social networking, web searching) amongst 10- to 17-year-old adolescents across 24 months.This study tracked the screen use of 1948 Australian students

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2018 BMC Public Health

125. Segmenting women eligible for cervical cancer screening using demographic, behavioural and attitudinal characteristics. (PubMed)

Segmenting women eligible for cervical cancer screening using demographic, behavioural and attitudinal characteristics. The best ways to communicate effectively to under-screened women about cervical cancer screening are unknown. Segmentation techniques create homogeneous segments of women in the population that are different from one another, and help to determine on whom communication efforts should be focused and how messaging should be tailored. We used segmentation techniques to better

2018 Preventive Medicine

126. Risk-adjusted colorectal cancer screening using the FIT and routine screening data: development of a risk prediction model. (PubMed)

Risk-adjusted colorectal cancer screening using the FIT and routine screening data: development of a risk prediction model. The faecal immunochemical test (FIT) is replacing the guaiac faecal occult blood test in colorectal cancer screening. Increased uptake and FIT positivity will challenge colonoscopy services. We developed a risk prediction model combining routine screening data with FIT concentration to improve the accuracy of screening referrals.Multivariate analysis used complete cases

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2018 British Journal of Cancer

127. Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age-Sex-Specific Thresholds for Test Positivity. (PubMed)

Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age-Sex-Specific Thresholds for Test Positivity. Background: Despite age and sex differences in fecal hemoglobin (f-Hb) concentrations, most fecal immunochemical test (FIT) screening programs use population-average cut-points for test positivity. The impact of age/sex-specific threshold on FIT accuracy and colonoscopy demand for colorectal cancer screening are unknown.Methods: Using data

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2018 Cancer Epidemiology & Biomarkers and Prevention

128. Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids (PubMed)

Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids Environmental toxins, such as lead and other heavy metals, pesticides, and other compounds, represent a significant health concern within the USA and around the world. Even in the twenty-first century, a plethora of cities and towns in the U.S. have suffered from exposures to lead in drinking water or other heavy metals in food or the earth, while there is a high possibility of further places

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2018 Frontiers in public health

129. Importance of Toxicokinetics to Assess the Utility of Zebrafish Larvae as Model for Psychoactive Drug Screening Using Meta-Chlorophenylpiperazine (mCPP) as Example (PubMed)

Importance of Toxicokinetics to Assess the Utility of Zebrafish Larvae as Model for Psychoactive Drug Screening Using Meta-Chlorophenylpiperazine (mCPP) as Example The number of new psychoactive substances (NPS) increases rapidly, harming society and fuelling the need for alternative testing strategies. These should allow the ever-increasing number of drugs to be tested more effectively for their toxicity and psychoactive effects. One proposed strategy is to complement rodent models

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2018 Frontiers in pharmacology

130. Identification of specific and common diagnostic antibody markers for gastrointestinal cancers by SEREX screening using testis cDNA phage library (PubMed)

Identification of specific and common diagnostic antibody markers for gastrointestinal cancers by SEREX screening using testis cDNA phage library The present study was planned to identify novel serum antibody markers for digestive organ cancers. We have used screening by phage expression cloning and identified novel fourteen antigens in this experiment. The presence of auto-antibodies against these antigens in serum specimens was confirmed by western blotting. As for auto-antibodies against

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2018 Oncotarget

131. Screening US Vietnam Veterans for Liver Fluke Exposure 5 Decades After the End of the War (PubMed)

Screening US Vietnam Veterans for Liver Fluke Exposure 5 Decades After the End of the War Clonorchiasis caused by Clonorchis sinensis and opisthorchiasis caused by Opisthorchis viverrini are prevalent in the Far East, including Vietnam. The causal relationship between the 2 liver flukes and cholangiocarcinoma (CCA) has been well documented. Cholangiocarcinoma, a rare tumor of bile ducts, usually occurs in the sixth-seventh decade of life. In the United States, 8000 people are diagnosed with CCA

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2018 Infectious Diseases in Clinical Practice (Baltimore, Md.)

132. Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor (PubMed)

Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor Structural studies of integral membrane proteins have been limited by the intrinsic conformational flexibility and the need to stabilize the proteins in solution. Stabilization by mutagenesis was very successful for structural biology of G protein-coupled receptors (GPCRs). However, it requires heavy protein engineering and may introduce structural deviations. Here we describe the use (...) of specific calixarenes-based detergents for native GPCR stabilization. Wild type, full length human adenosine A2A receptor was used to exemplify the approach. We could stabilize native, glycosylated, non-aggregated and homogenous A2AR that maintained its ligand binding capacity. The benefit of the preparation for fragment screening, using the Saturation-Transfer Difference nuclear magnetic resonance (STD-NMR) experiment is reported. The binding of the agonist adenosine and the antagonist caffeine were

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2018 Scientific reports

133. High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin–myosin structure and function (PubMed)

High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin–myosin structure and function We have used a novel time-resolved FRET (TR-FRET) assay to detect small-molecule modulators of actin-myosin structure and function. Actin-myosin interactions play crucial roles in the generation of cellular force and movement. Numerous mutations and post-translational modifications of actin or myosin disrupt muscle function and cause life-threatening syndromes

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2018 The Journal of biological chemistry

134. A Multi-Anatomical Retinal Structure Segmentation System for Automatic Eye Screening Using Morphological Adaptive Fuzzy Thresholding (PubMed)

A Multi-Anatomical Retinal Structure Segmentation System for Automatic Eye Screening Using Morphological Adaptive Fuzzy Thresholding Eye exam can be as efficacious as physical one in determining health concerns. Retina screening can be the very first clue for detecting a variety of hidden health issues including pre-diabetes and diabetes. Through the process of clinical diagnosis and prognosis; ophthalmologists rely heavily on the binary segmented version of retina fundus image; where

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2018 IEEE journal of translational engineering in health and medicine

135. Identification of a Water-Coordinating HER2 Inhibitor by Virtual Screening Using Similarity-Based Scoring (PubMed)

Identification of a Water-Coordinating HER2 Inhibitor by Virtual Screening Using Similarity-Based Scoring Human epidermal growth factor receptor 2 (HER2) is a validated breast cancer drug target for small molecule inhibitors that target the ATP-binding pocket of the kinase domain. In this work, a large-scale virtual screen was performed to a novel homology model of HER2, in a hypothesized "fully active" state, that considered water-mediated interactions during the prioritization of compounds

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2018 Biochemistry

136. Pilot Study of Vitamin D Screening Use in Peripheral Arterial Disease Patient Over Maximum Distance Walking

Pilot Study of Vitamin D Screening Use in Peripheral Arterial Disease Patient Over Maximum Distance Walking Pilot Study of Vitamin D Screening Use in Peripheral Arterial Disease Patient Over Maximum Distance Walking - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Pilot Study of Vitamin D Screening Use in Peripheral Arterial Disease Patient Over Maximum Distance Walking The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2018 Clinical Trials

137. HCC Screening Using DNA Methylation Changes in ctDNA

HCC Screening Using DNA Methylation Changes in ctDNA HCC Screening Using DNA Methylation Changes in ctDNA - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. HCC Screening Using DNA Methylation Changes in ctDNA

2018 Clinical Trials

138. Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNA

Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNA Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNA - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNA The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03499678 Recruitment Status : Recruiting First Posted : April 17, 2018 Last

2018 Clinical Trials

139. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults (PubMed)

Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults Reducing premature mortality associated with age-related chronic diseases, such as cancer and cardiovascular disease, is an urgent priority. We report early results using genomics in combination with advanced imaging and other clinical testing to proactively screen for age-related chronic disease risk among adults. We enrolled active, symptom-free adults in a study of screening (...) for age-related chronic diseases associated with premature mortality. In addition to personal and family medical history and other clinical testing, we obtained whole-genome sequencing (WGS), noncontrast whole-body MRI, dual-energy X-ray absorptiometry (DXA), global metabolomics, a new blood test for prediabetes (Quantose IR), echocardiography (ECHO), ECG, and cardiac rhythm monitoring to identify age-related chronic disease risks. Precision medicine screening using WGS and advanced imaging along

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2018 Proceedings of the National Academy of Sciences of the United States of America

140. Factors Associated with Participation in Pulmonary Tuberculosis Screening Using Chest X-Ray among Diabetes Mellitus Type II Patients in Denpasar, Bali, Indonesia (PubMed)

Factors Associated with Participation in Pulmonary Tuberculosis Screening Using Chest X-Ray among Diabetes Mellitus Type II Patients in Denpasar, Bali, Indonesia Diabetes mellitus (DM) increases the risk of developing pulmonary tuberculosis (TB) disease. Therefore, pulmonary TB screening among DM patients is essential. This study aimed to identify factors associated with participation of DM type II patients in pulmonary TB screening using chest X-ray. This was a cross-sectional analytic study

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2018 Tuberculosis research and treatment

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