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81. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. (Full text)

A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Yeast two-hybrid (Y2H) is a well-established genetics-based system that uses yeast to selectively display binary protein-protein interactions (PPIs). To meet the current need to unravel complex PPI networks, several adaptations have been made to establish medium- to high-throughput Y2H screening platforms, with several having successfully incorporated the use of the next-generation sequencing (NGS

2018 PLoS ONE PubMed abstract

82. Screen time and social media: Interventions to protect our children’s health

influencers on children’s screen time habits, and it is imperative that they set an example of healthy online behaviours. The UK CMOs commend the work of the Royal College of Paediatrics and Child Health in developing questions and practical tips to support families’ discussion of their screen use . [7] The UK CMOs have also produced advice for parents on how to incorporate screen use into health development. [ 8] To better understand the intersection of screen time and health more comprehensive research (...) Screen time and social media: Interventions to protect our children’s health Screen time and social media: Interventions to protect our children’s health - The BMJ ---> An appropriate mechanism for measuring children’s digital engagement needs to be developed Today’s children have screens integrated into daily life from an early age. There are advantages of having this online world at their fingertips, but the potential threat to their health and development has become of increasing concern

2019 The BMJ Blog

83. Randomised controlled trial: Fifty years of age-based screening: time for a new risk-based screening approach

Randomised controlled trial: Fifty years of age-based screening: time for a new risk-based screening approach Fifty years of age-based screening: time for a new risk-based screening approach | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Fifty years of age-based screening: time for a new risk-based screening approach Article Text Prevention Randomised controlled trial Fifty years of age-based screening: time for a new risk-based

2014 Evidence-Based Medicine

84. Cervical cancer incidence after normal cytological sample in routine screening using SurePath, ThinPrep, and conventional cytology: population based study. (Full text)

Cervical cancer incidence after normal cytological sample in routine screening using SurePath, ThinPrep, and conventional cytology: population based study. Objective To compare the cumulative incidence of cervical cancer diagnosed within 72 months after a normal screening sample between conventional cytology and liquid based cytology tests SurePath and ThinPrep.Design Retrospective population based cohort study.Setting Nationwide network and registry of histo- and cytopathology

2017 BMJ PubMed abstract

85. Mobile Health Technology for Atrial Fibrillation Screening Using Photoplethysmography-Based Smart Devices: The HUAWEI Heart study. (Abstract)

Mobile Health Technology for Atrial Fibrillation Screening Using Photoplethysmography-Based Smart Devices: The HUAWEI Heart study. Low detection and nonadherence are major problems in current management approaches for patients with suspected atrial fibrillation (AF). Mobile health (mHealth) devices may enable earlier AF detection, and improved AF management.To investigate the effectiveness of AF screening in a large population-based cohort using smart device based photoplethysmography (PPG

2019 Journal of the American College of Cardiology

86. Non-invasive screening using ventilatory gas analysis to distinguish between chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. (Full text)

Non-invasive screening using ventilatory gas analysis to distinguish between chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. Clinical presentations associated with chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH) at rest are highly similar. Differentiating between CTEPH and PAH using non-invasive techniques remains challenging. Thus, we examined whether analysis of ventilatory gas in response to postural changes

2019 Respirology PubMed abstract

87. Does a novel diagnostic pathway including blood-based risk prediction and MRI-targeted biopsies outperform prostate cancer screening using prostate-specific antigen and systematic prostate biopsies? - protocol of the randomised study STHLM3MRI. (Full text)

Does a novel diagnostic pathway including blood-based risk prediction and MRI-targeted biopsies outperform prostate cancer screening using prostate-specific antigen and systematic prostate biopsies? - protocol of the randomised study STHLM3MRI. Prostate cancer is a leading cause of cancer death among men in the Western world. Early detection of prostate cancer has been shown to decrease mortality, but has limitations with low specificity leading to unnecessary biopsies and overdiagnosis of low

2019 BMJ open Controlled trial quality: uncertain PubMed abstract

88. Investigating the feasibility of stratified breast cancer screening using a masking risk predictor. (Full text)

Investigating the feasibility of stratified breast cancer screening using a masking risk predictor. Women with dense breasts face a double risk for breast cancer; they are at a higher risk for development of breast cancer than those with less dense breasts, and there is a greater chance that mammography will miss detection of a cancer in dense breasts due to the masking effect of surrounding fibroglandular tissue. These women may be candidates for supplemental screening. In this study

2019 Breast cancer research : BCR PubMed abstract

89. Feasibility of Automated Cameras to Measure Screen Use in Adolescents. (Abstract)

Feasibility of Automated Cameras to Measure Screen Use in Adolescents. The influence of screens and technology on adolescent well-being is controversial and there is a need to improve methods to measure these behaviors. This study examines the feasibility and acceptability of using automated wearable cameras to measure evening screen use in adolescents.A convenience sample of adolescents (aged 13-17 years, n=15) wore an automated camera for 3 evenings from 5:00pm to bedtime. The camera (Brinno (...) TLC120) captured an image every 15 seconds. Fieldwork was completed between October and December 2017, and data analyzed in 2018. Feasibility was examined by quality of the captured images, wear time, and whether images could be coded in relation to contextual factors (e.g., type of screen and where screen use occurred). Acceptability was examined by participant compliance to the protocol and from an exit interview.Data from 39 evenings were analyzed (41,734 images), with a median of 268 minutes per

2019 American journal of preventive medicine

90. Systematic screening using FRAX<sup>®</sup> leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial. (Abstract)

Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial. In the large community-based SCOOP trial, systematic fracture risk screening using FRAX® led to greater use of AOM and greater adherence, in women at high fracture risk, compared with usual care.In the SCreening of Older wOmen for Prevention of fracture (SCOOP) trial, we investigated the effect of the screening intervention on subsequent long (...) was associated with poorer adherence (OR per year increase in age 0.96 [95% CI 0.93, 0.99], p = 0.01), whereas history of parental hip fracture was associated with greater rate adherence (OR 1.67 [95% CI 1.23, 2.26], p < 0.01).Systematic fracture risk screening using FRAX® leads to greater use of AOM and greater adherence, in women at high fracture risk, compared with usual care.

2019 Osteoporosis International

91. Self- screening using the Edinburgh post natal depression scale for mothers and fathers to initiate early help seeking behaviours. (Abstract)

Self- screening using the Edinburgh post natal depression scale for mothers and fathers to initiate early help seeking behaviours. The forthcoming birth of a new baby and the life changes that occur can present parents with a range of challenges. While recognised in mothers, postnatal depression is not well researched in fathers; especially considering that up to 25% of men report experiencing depression in the ante and postnatal periods. The aim of this study was to test a self-screening tool

2019 Archives of Psychiatric Nursing Controlled trial quality: uncertain

92. Visual Acuity Assessment and Vision Screening Using a Novel Smartphone Application. (Abstract)

Visual Acuity Assessment and Vision Screening Using a Novel Smartphone Application. To evaluate a smartphone-based application's (Peek Acuity) ability to assess visual acuity and screen for ocular conditions in children, we compared visual acuity assessment between Peek Acuity and the pediatric ophthalmology examination and evaluated Peek Acuity's ability to identify children with referable ocular conditions.We prospectively recruited 111 children age 3-17 years, presenting to a pediatric

2019 Journal of Pediatrics Controlled trial quality: uncertain

93. Cost-effectiveness of osteoporosis screening using biomechanical computed tomography for patients with a previous abdominal CT. (Abstract)

Cost-effectiveness of osteoporosis screening using biomechanical computed tomography for patients with a previous abdominal CT. Osteoporosis screening rates by DXA are low (9.5% women, 1.7% men) in the U.S. Medicare population aged 65 and older. Addressing this care gap, we estimated the benefits of a validated osteoporosis diagnostic test suitable for patients age 65 and older with an abdominal computed tomography (CT) scan taken for any indication but without a recent DXA. Our analysis (...) treatment adherence, and longer treatment duration. When the sensitivity and specificity of BCT were set to those for DXA, the prevented hip fractures versus usual care remained high (2.7 per 1,000 women; 1.5 per 1,000 men), indicating the importance of high screening rates on clinical efficacy. Therefore, for patients with a previously taken abdominal CT and without a recent DXA, osteoporosis screening using biomechanical computed tomography may be a cost-effective alternative to current usual care

2019 Journal of Bone and Mineral Research

94. Objective vision screening using PlusoptiX for children aged 3-11 years in rural Turkey. (Full text)

Objective vision screening using PlusoptiX for children aged 3-11 years in rural Turkey. This population based cross sectional study was conducted to detect amblyopia risk factors and myopia in a rural district of Northwestern Turkey by using PlusoptiX S12R (Photoscreener PlusoptiX Inc., Nuremberg, Germany).Children from 38 rural schools in Caycuma district of Zonguldak Turkey underwent vision screening in their school using PlusoptiX S12 photoscreener. Data were analyzed using the factory

2019 BMC Ophthalmology PubMed abstract

95. Quality of Care and Preventive Screening Use in the CareFirst Patient-Centered Medical Home Program. (Abstract)

Quality of Care and Preventive Screening Use in the CareFirst Patient-Centered Medical Home Program. Despite their value, comprehensive diabetes care and screening for common cancers remain underutilized. We examined the association between participation in a patient-centered medical home (PCMH) program with strong financial incentives and receipt of preventive care in the first 5 years after program launch. Using multivariate regression analysis, we compared outcomes for adults under the care

2019 Journal for Healthcare Quality

96. The Impacts of the ACA Medicaid Expansions on Cancer Screening Use by Primary Care Provider Supply. (Abstract)

The Impacts of the ACA Medicaid Expansions on Cancer Screening Use by Primary Care Provider Supply. Recent studies of the impacts of the Affordable Care Act (ACA) Medicaid expansions on cancer screening use have mostly found insignificant effects. We posit that these findings mask meaningful heterogeneity in impacts depending on availability of primary care providers.This study examined the impacts of the ACA Medicaid expansions on cancer screening use separately by state-level supply (...) of primary care providers.We used data from the 2012 and 2016 Behavioral Risk Factor Surveillance System surveys to measure use of mammograms, Pap smear tests, blood stool tests, and sigmoidoscopy/colonoscopy for age groups recommended receiving these tests. The main analytical sample included 24,878-31,890 individuals with household income below 138% Federal Poverty Line. We used a difference-in-differences design comparing pre-post expansion changes in cancer screening use between expanding

2019 Medical Care

97. Frailty Screening Using the Electronic Health Record within a Medicare Accountable Care Organization. (Full text)

Frailty Screening Using the Electronic Health Record within a Medicare Accountable Care Organization. The accumulation of deficits model for frailty has been used to develop an Electronic Health Record (EHR) frailty index (eFI) that has been incorporated into British guidelines for frailty management. However, there have been limited applications of EHR-based approaches in the United States.We constructed an adapted eFI for patients in our Medicare Accountable Care Organization (ACO, N=12,798

2019 Biological Sciences and Medical Sciences PubMed abstract

98. To Each Stress Its Own Screen: A Cross-Sectional Survey of the Patterns of Stress and Various Screen Uses in Relation to Self-Admitted Screen Addiction. (Full text)

To Each Stress Its Own Screen: A Cross-Sectional Survey of the Patterns of Stress and Various Screen Uses in Relation to Self-Admitted Screen Addiction. The relationship between stress and screen addiction is often studied by exploring a single aspect of screen-related behavior in terms of maladaptive dependency or the risks associated with the content. Generally, little attention is given to the pattern of using different screens for different types of stressors, and variations arising from (...) ) differences in stress types in relation to subjective screen addiction and different types of needs for screens. We hypothesized that interindividual heterogeneity in screen-related behavior would reflect coping differences in dealing with different stressors.A multifactorial Web-based survey was conducted to gather data about screen-related behaviors (such as screen time, internet addiction, and salience of different types of screens and related activities), and different sources of stress (emotional

2019 Journal of medical Internet research PubMed abstract

99. Addressing priority challenges in the detection and assessment of colorectal polyps from capsule endoscopy and colonoscopy in colorectal cancer screening using machine learning. (Full text)

Addressing priority challenges in the detection and assessment of colorectal polyps from capsule endoscopy and colonoscopy in colorectal cancer screening using machine learning. Colorectal capsule endoscopy (CCE) is a potentially valuable patient-friendly technique for colorectal cancer screening in large populations. Before it can be widely applied, significant research priorities need to be addressed. We present two innovative data science algorithms which can considerably improve acquisition

2019 Acta Oncologica PubMed abstract

100. Questionnaires and checklists for central auditory processing screening used in Brazil: a systematic review. (Full text)

Questionnaires and checklists for central auditory processing screening used in Brazil: a systematic review. The action of listening involves a complex interaction between the peripheral and central auditory systems. Central auditory processing disorder can be described as any problem in one or more auditory abilities. Literature reports that behavioral questionnaires and checklists can be applied to screen individuals at risk for central auditory processing disorder.To identify and analyze

2019 Brazilian journal of otorhinolaryngology PubMed abstract

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