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189681. Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis. (PubMed)

Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis. In animals, excessive core body temperatures have been documented to cause malformations; neural tube defects (NTDs) are among the most frequently reported. In humans, data are inconclusive and often conflicting. The objective of our report is to determine the risk for neural tube defects associated with maternal hyperthermia in early pregnancy.We conducted a systematic review and meta (...) -analysis to evaluate available evidence on this topic in humans. MEDLINE, EMBASE, references from published reports, and biologic abstracts from meetings were searched for relevant studies. Reviewers evaluated all the retrieved articles and extracted the relevant data. Individual and summary odds ratios and relative risks were calculated using the Mantel-Haenszel method.Fifteen studies, reporting on 1,719 cases and 37,898 noncases, were included in the meta-analysis. The overall odds ratio for neural

2005 Epidemiology (Cambridge, Mass.)

189682. Reoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis. (Full text)

Reoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis. 15710999 2005 03 15 2018 11 13 0017-5749 54 3 2005 Mar Gut Gut Reoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis. 440-1 Demeester S R SR eng Comment Letter England Gut 2985108R 0017-5749 AIM IM Gut. 2004 Jul;53(7):925-30 15194636 Adenocarcinoma therapy Chemotherapy, Adjuvant Esophageal Neoplasms therapy Humans Meta-Analysis as Topic Radiotherapy, Adjuvant 2005 2

2005 Gut PubMed

189683. Asymptomatic postoperative deep vein thrombosis and the development of postthrombotic syndrome. A systematic review and meta-analysis. (PubMed)

Asymptomatic postoperative deep vein thrombosis and the development of postthrombotic syndrome. A systematic review and meta-analysis. Perioperative antithrombotic clinical regimens have reduced the incidence of postoperative deep venous thrombosis (DVT). Long-term effects of asymptomatic postoperative DVT have been studied in a number of clinical trials and the present review describes the clinical significance of asymptomatic postoperative DVT regarding the possible development (...) of postthrombotic syndrome (PTS). We performed a systematic review of reference databases focusing upon studies including patients suspected of having postoperative DVT and reporting subsequent cases of PTS at the end of a well-defined follow-up period. The included studies were stratified according to type of screening method and applied statistics. Over-all evaluation included meta-analyses based upon the Cochrane software package. The overall relative risk of developing PTS was 1.58 (95% confidence intervals

2005 Thrombosis and haemostasis

189684. CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis. (PubMed)

CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis. Two common variant alleles of the cytochrome CYP2C9 (CYP2C9*2 and CYP2C9*3) lead to reduced warfarin metabolism in vitro and in vivo. The study objective was to examine the strength and quality of existing evidence about CYP2C9 gene variants and clinical outcomes in warfarin-treated patients.The study was a systematic review and meta-analysis. Multiple electronic

2005 Genetics in medicine : official journal of the American College of Medical Genetics

189685. Atrial flutter and the risk of thromboembolism: a systematic review and meta-analysis. (PubMed)

Atrial flutter and the risk of thromboembolism: a systematic review and meta-analysis. We conducted a systematic review and meta-analysis of observational studies to assess the risk of thromboembolism associated with atrial flutter.MEDLINE, EMBASE, bibliographies, and consultation with clinical experts were used to identify studies that report the risk of thromboembolism associated with attempted cardioversion and longer-term risk in chronic atrial flutter. The review process and data

2005 The American journal of medicine

189686. The accuracy of MRI in diagnosis of suspected deep vein thrombosis: systematic review and meta-analysis. (PubMed)

The accuracy of MRI in diagnosis of suspected deep vein thrombosis: systematic review and meta-analysis. Magnetic resonance imaging (MRI) may be used to diagnose deep vein thrombosis (DVT) in patients for whom ultrasound examination is inappropriate or unfeasible. We undertook a systematic review of the literature and meta-analysis to estimate the diagnostic accuracy of MRI for DVT. We searched databases of medical literature and citation lists of retrieved articles. We selected studies (...) that compared MRI with a reference standard in patients with suspected DVT or suspected pulmonary embolus, or high-risk asymptomatic patients. Data were analysed by random effects meta-analysis. We included 14 articles in the meta-analysis. Most compared MRI with venography in patients with clinically suspected DVT. The pooled estimate of sensitivity was 91.5% (95% CI: 87.5-94.5%) and the pooled estimate of specificity was 94.8% (95% CI: 92.6-96.5%). Sensitivity for proximal DVT was higher than sensitivity

2007 European radiology

189687. Spinal cord stimulation in complex regional pain syndrome and refractory neuropathic back and leg pain/failed back surgery syndrome: results of a systematic review and meta-analysis. (PubMed)

Spinal cord stimulation in complex regional pain syndrome and refractory neuropathic back and leg pain/failed back surgery syndrome: results of a systematic review and meta-analysis. The drive for good quality evidence has highlighted the importance of well-conducted systematic reviews and meta-analyses that critically evaluate and grade studies for new or existing therapies. A systematic review and meta-analysis was performed to review the efficacy, safety, and cost effectiveness of spinal

2006 Journal of pain and symptom management

189688. Coffee and gastric cancer: systematic review and meta-analysis. (PubMed)

Coffee and gastric cancer: systematic review and meta-analysis. We systematically reviewed the literature on the association between coffee consumption and gastric cancer and performed a meta-analysis of the results. Published cohort and case-control studies were identified in PubMed and reference lists. Random effects meta-analysis was used to pool effects from 23 studies, and heterogeneity was explored by stratification and meta-regression. The odds ratio (OR) for the overall association (...) ) for the two studies from South America. In this meta-analysis we found no adverse effect of coffee associated with gastric cancer. Knowledge on the level of exposure to different coffee constituents may provide a deeper understanding of this reassuring result and the real role of coffee on cancer risk.

2006 Cadernos de Saúde Pública / Ministério da Saúde

189689. A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases. (Full text)

A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases. This systematic review attempted to summarize the associations between the Asn291Ser variant in the lipoprotein lipase (LPL) gene and dyslipidemia, the risk of type 2 diabetes mellitus (T2DM), and coronary heart disease (CHD). In addition, the relationships between the Asn291Ser variant and other metabolic diseases such as obesity and high blood pressure were also investigated (...) in this systematic review. We systematically reviewed the literature by means of a meta-analysis. Twenty-one articles, including 19,246 white subjects, were selected for this meta-analysis. The summary standardized mean difference (SMD) of plasma triglyceride (TG) for carriers compared with noncarriers of the Asn291Ser variant was 3.23 (P < 0.00001). The summary SMD of plasma HDL-cholsterol (HDL-C) for carriers compared with noncarriers of the Asn291Ser variant was -3.42 (P < 0.0001). The summary SMD

2006 Journal of lipid research PubMed

189690. Prenatal exposure to misoprostol and congenital anomalies: systematic review and meta-analysis. (PubMed)

Prenatal exposure to misoprostol and congenital anomalies: systematic review and meta-analysis. The present systematic review was proposed with the objective of estimating the risk of congenital anomalies and other adverse events in children exposed to misoprostol during fetal life. The data source consisted of case-control studies that analyzed the effect of prenatal exposure to misoprostol on the pregnancy outcome, which were located in electronic databases and published up to June 2005 (...) . The outcomes of interest included congenital anomalies, fetal death, low birth weight and prematurity. The odds ratios (OR) for the individual studies were pooled by meta-analysis. Sensitivity tests and heterogeneity analysis were performed. Four studies involving 4899 cases of congenital anomalies and 5742 controls were included in accordance with the selection criteria. None of the studies analyzed other adverse effects from misoprostol on the outcome from gestation. Increased risks of congenital

2006 Reproductive toxicology (Elmsford, N.Y.)

189691. Male circumcision and risk of syphilis, chancroid, and genital herpes: a systematic review and meta-analysis. (Full text)

Male circumcision and risk of syphilis, chancroid, and genital herpes: a systematic review and meta-analysis. Male circumcision is associated with reduced risk of HIV infection. This may be partly because of a protective effect of circumcision on other sexually transmitted infections (STI), especially those causing genital ulcers, but evidence for such protection is unclear. Our objective was to conduct a systematic review and meta-analyses of the associations between male circumcision (...) ).This first systematic review of male circumcision and ulcerative STI strongly indicates that circumcised men are at lower risk of chancroid and syphilis. There is less association with HSV-2. Potential male circumcision interventions to reduce HIV in high risk populations may provide additional benefit by protecting against other STI.

2006 Sexually transmitted infections PubMed

189692. Letter by Rundek et al regarding article, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis". (Full text)

Letter by Rundek et al regarding article, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis". 17724268 2007 09 14 2007 11 15 1524-4539 116 9 2007 Aug 28 Circulation Circulation Letter by Rundek et al regarding article, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis". e317; author reply e318 Rundek Tatjana T Brook Robert D RD Spence J David JD eng (...) Comment Letter United States Circulation 0147763 0009-7322 AIM IM Circulation. 2007 Jan 30;115(4):459-67 17242284 Cardiovascular Diseases epidemiology Carotid Arteries pathology Carotid Artery Diseases epidemiology Humans Meta-Analysis as Topic Stroke epidemiology Tunica Media pathology 2007 8 29 9 0 2007 9 15 9 0 2007 8 29 9 0 ppublish 17724268 116/9/e317 10.1161/CIRCULATIONAHA.107.696385

2007 Circulation PubMed

189693. Quality of life assessed with the Medical Outcomes Study Short Form 36-Item Health Survey of patients on renal replacement therapy: a systematic review and meta-analysis. (Full text)

Quality of life assessed with the Medical Outcomes Study Short Form 36-Item Health Survey of patients on renal replacement therapy: a systematic review and meta-analysis. The Medical Outcomes Study Short Form 36-Item Health Survey (SF-36) is the most widely used generic instrument to estimate quality of life of patients on renal replacement therapy. Purpose of this study was to summarize and compare the published literature on quality of life of hemodialysis (HD), peritoneal dialysis (PD

2007 Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research PubMed

189694. Letter to the editor concerning Petignat et al.'s "Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA testing? A systematic review and meta-analysis." Gynecol Oncol 2007;105(2): 530-535. (PubMed)

Letter to the editor concerning Petignat et al.'s "Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA testing? A systematic review and meta-analysis." Gynecol Oncol 2007;105(2): 530-535. 17904206 2008 01 07 2007 12 06 1095-6859 107 3 2007 Dec Gynecologic oncology Gynecol. Oncol. Letter to the editor concerning Petignat et al.'s "Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA (...) testing? A systematic review and meta-analysis." Gynecol Oncol 2007;105(2): 530-535. 595-6; author reply 596-7 Pretorius Robert G RG Belinson Jerome L JL eng Comment Letter 2007 09 27 United States Gynecol Oncol 0365304 0090-8258 0 DNA, Viral IM Gynecol Oncol. 2007 May;105(2):530-5 17335880 Cervix Uteri pathology virology DNA, Viral analysis Female Humans Papillomaviridae genetics isolation & purification Papillomavirus Infections pathology virology Self-Examination Specimen Handling methods Vaginal

2007 Gynecologic oncology

189695. Lack of association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR) and Panic Disorder: a systematic review and meta-analysis. (Full text)

Lack of association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR) and Panic Disorder: a systematic review and meta-analysis. The aim of this study is to assess the association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR) and Panic Disorder (PD).This is a systematic review and meta-analysis of case-control studies with unrelated individuals of any ethnic origin examining the role of the 5-HTTLPR in PD according to standard diagnostic criteria (DSM (...) intervals.Nineteen potential articles were identified, and 10 studies were included in this meta-analysis. No statistically significant association between 5-HTTLPR and PD was found, OR = 0.91 (CI95% 0.80 to 1.03, p = 0.14). Three sub-analyses divided by ethnicity, control group quality and Agoraphobia comorbidity also failed to find any significant association. No evidence of heterogeneity was found between studies in the analyses.Results from this systematic review do not provide evidence to support

2007 Behavioral and brain functions : BBF PubMed

189696. Volume of tobacco advertising in African American markets: systematic review and meta-analysis. (Full text)

Volume of tobacco advertising in African American markets: systematic review and meta-analysis. African Americans currently bear the greatest burden of morbidity and mortality due to smoking, and exposure to pro-tobacco media messages predicts smoking. This study compared the concentration (proportion of media messages that are for tobacco) and density (pro-tobacco media messages per person) of pro-tobacco media messages between African American and Caucasian markets.We searched Medline (1966 (...) eligibility criteria, including seven comparing billboard/signage in African American and Caucasian markets and four comparing magazine advertising in African American and Caucasian markets. Meta-analysis estimated a pooled odds ratio of 1.7 (95% confidence interval [CI] 1.1, 2.6) for a given billboard being smoking-related in African American vs. Caucasian market areas (i.e., concentration). The pooled rate ratio of the density of smoking-related billboards was 2.6 (95% CI 1.5, 4.7) in African American

2007 Public health reports (Washington, D.C. : 1974) PubMed

189697. The prehospital 12-lead electrocardiogram's effect on time to initiation of reperfusion therapy: a systematic review and meta-analysis of existing literature. (PubMed)

The prehospital 12-lead electrocardiogram's effect on time to initiation of reperfusion therapy: a systematic review and meta-analysis of existing literature. The prehospital electrocardiogram (ECG) is becoming the standard of care of suspected cardiac chest pain. We evaluated the evidence regarding the prehospital ECG and sought to quantify the reduction in time to reperfusion therapy attributable to the prehospital ECG. We conducted a systematic review and analyzed studies that were conducted (...) in emergency medical systems relevant to providers in the United States. The papers were limited to studies that reported original data that compared prehospital ECG to no prehospital ECG groups. Four studies containing 99 patients met the inclusion criteria. A meta-analysis of these studies revealed a difference of 24.7 (95% confidence interval, 16.7-32.7) minutes. Providers now have a quantified value of the prehospital ECG based on the best published evidence. In addition, this search showed

2005 American Journal of Emergency Medicine

189698. Caregiver-specific outcomes in antidementia clinical drug trials: a systematic review and meta-analysis. (PubMed)

Caregiver-specific outcomes in antidementia clinical drug trials: a systematic review and meta-analysis. To describe the range of caregiver-specific outcomes and approaches to their study within antidementia drug trials and to quantify the effect of cholinesterase inhibitors on burden and active time use of caregivers of persons with Alzheimer's disease (AD).Systematic review of English-language publications and unpublished reports of antidementia clinical drug trials that included caregiver

2005 Journal of the American Geriatrics Society

189699. Use of prostate-specific antigen (PSA) isoforms for the detection of prostate cancer in men with a PSA level of 2-10 ng/ml: systematic review and meta-analysis. (PubMed)

Use of prostate-specific antigen (PSA) isoforms for the detection of prostate cancer in men with a PSA level of 2-10 ng/ml: systematic review and meta-analysis. Measurement of serum prostate-specific antigen (PSA) for the detection of prostate cancer has poor specificity in men with PSA levels between 2 and 10 ng/ml. It has been suggested that measurement of the ratio of free to total PSA (f/tPSA) or complexed PSA (cPSA) might offer an improvement. We performed a systematic review and meta (...) -analysis to evaluate the diagnostic performance of these tests among men with PSA levels between 2 and 10 ng/ml.Data on sensitivity and specificity were extracted from 66 eligible studies. Likelihood ratios and summary receiver operating characteristic curves were estimated and possible sources of heterogeneity between studies examined.Use of the f/tPSA or the cPSA test improved diagnostic performance among men with a total PSA (tPSA) of 2-4 or 4-10 ng/ml compared to tPSA alone. The diagnostic

2005 European urology

189700. Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review. (Full text)

Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review. A number of studies have investigated two common polymorphisms in the beta(2)-adrenoceptor gene, Arg/Gly16 and Gln/Glu27, in relation to asthma susceptibility. The authors performed a meta-analysis of each polymorphism, as well as haplotype analysis, for adult and pediatric populations separately, using published data, supplemented by additional data requested from

2005 American journal of epidemiology PubMed

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