How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

189,729 results for

"metaanalysis" OR "meta analysis" OR "systematic review"〈=en

by
...
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

189521. Systematic review and meta-analysis of observational studies on the prevalence of fractures in coeliac disease. (PubMed)

Systematic review and meta-analysis of observational studies on the prevalence of fractures in coeliac disease. Evidence of an increased bone fracture risk in coeliac disease is on debate. Our aim was to review systematically the current published information on fractures in coeliac disease and to perform a meta-analysis.Case-control and cohort designs were identified by searching MEDLINE (1966-April 2007) and LILACS (1982-April 2007). Participants were adult coeliac disease patients of any sex (...) ) and sensitivity analysis was performed based on the reported quality and design type.While 60 of 405 studies met the initial screening criteria, only 8 met inclusion criteria after detailed review. These studies evaluated a total of 20,955 coeliac disease patients having 1819 (8.7%) fractures and 96,777 controls with 5955 (6.1%) fractures (pooled odds ratio=1.43; 95% confidence interval 1.15-1.78) with considerable heterogeneity among studies (p<0.00001).Our meta-analysis confirms a significant association

2007 Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

189522. Diagnostic utility of pleural fluid carcinoembryonic antigen and CYFRA 21-1 in patients with pleural effusion: a systematic review and meta-analysis. (PubMed)

Diagnostic utility of pleural fluid carcinoembryonic antigen and CYFRA 21-1 in patients with pleural effusion: a systematic review and meta-analysis. Pleural effusions (PE) are the most common complications that may be produced by a wide variety of diseases. A large number of studies exploring the role of carcinoembryonic antigen (CEA) and cytokeratin fragment 19 (CYFRA 21-1) marker in differential diagnosis of PE have been published, employing differing methodologies with sometimes conflicting (...) results. A comprehensive systematic review would be useful to synthesize the currently available bulk of information. The objective of this work was to assess and compare the overall value of pleural fluid CEA and CYFRA 21-1 in differential diagnosis of PEs with a meta-analysis. All the English and Chinese published studies for differential diagnosis of PEs by pleural fluid CEA and CYFRA 21-1 were collected. Methodological quality of the included studies was evaluated. Pooled sensitivity

2007 Journal of clinical laboratory analysis

189523. Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis. (PubMed)

Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis. Ultrasound-based transient elastography is a promising noninvasive alternative to liver biopsy for detecting hepatic fibrosis. However, its overall test performance in various settings remains unknown. The aims of this study were to perform a systematic review and meta-analysis of diagnostic accuracy studies comparing ultrasound-based transient elastography with liver biopsy (...) for hepatic fibrosis.Electronic and manual bibliographic searches to identify potential studies were performed. Selection of studies was based on reported accuracy of ultrasound-based transient elastography compared with liver biopsy. Data extraction was performed independently by 2 reviewers. Meta-analysis combined the sensitivities, specificities, and likelihood ratios of individual studies. Extent and reasons for heterogeneity were assessed.Nine studies in full publication were identified. For patients

2007 Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

189524. Worsening renal function and prognosis in heart failure: systematic review and meta-analysis. (PubMed)

Worsening renal function and prognosis in heart failure: systematic review and meta-analysis. Renal impairment is associated with increased mortality in heart failure (HF). Recently, reports suggest that worsening renal function (WRF) is another predictor of clinical outcome in HF. The present study was designed to establish the proportion of patients with HF that exhibits (WRF) and the associated risk for mortality and hospitalization by conducting a systematic review and meta-analysis.A (...) systematic search of MEDLINE revealed 8 studies on the relationship between WRF and mortality in 18,634 patients with HF. The mortality risk associated with WRF was estimated using random-effects meta-analysis. WRF was defined as an increase in serum creatinine > or = 0.2 mg/dL or a corresponding decrease in estimated glomerular filtration rate > or = 5 mL x min x 1.73 m2. Subgroup analysis included differentiation between in- and out-hospital patients, degree of WRF and time until end point occurrence

2007 Journal of cardiac failure

189525. Effectiveness of routine visits and routine tests in detecting isolated locoregional recurrences after treatment for early-stage invasive breast cancer: a meta-analysis and systematic review. (PubMed)

Effectiveness of routine visits and routine tests in detecting isolated locoregional recurrences after treatment for early-stage invasive breast cancer: a meta-analysis and systematic review. To review the effectiveness of routine visits and routine tests in detecting isolated locoregional recurrences in asymptomatic patients after treatment for early-stage invasive breast cancer.Systematic review and meta-analysis. The proportion of isolated locoregional recurrences diagnosed during routine (...) or other tests, nor if the detection of asymptomatic isolated recurrences had any influence on potential for cure or quality of life. As the overall quality of the included studies and the overall incidence of isolated locoregional recurrences are low, this systematic review highlights the need for prospective comparative studies on cost-effective strategies for the follow-up of patients after a diagnosis of breast cancer.

2004 Journal of clinical oncology : official journal of the American Society of Clinical Oncology

189526. Delayed versus early pushing in women with epidural analgesia: a systematic review and meta-analysis. (PubMed)

Delayed versus early pushing in women with epidural analgesia: a systematic review and meta-analysis. 15663115 2005 02 01 2018 12 01 1470-0328 111 12 2004 Dec BJOG : an international journal of obstetrics and gynaecology BJOG Delayed versus early pushing in women with epidural analgesia: a systematic review and meta-analysis. 1333-40 Roberts Christine L CL Centre for Perinatal Health Services Research, School of Public Health, University of Sydney, New South Wales, Australia. Torvaldsen Siranda (...) S Cameron Carolyn A CA Olive Emily E eng Comparative Study Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Review Systematic Review England BJOG 100935741 1470-0328 AIM IM Analgesia, Epidural methods Analgesia, Obstetrical methods Delivery, Obstetric methods Female Humans Labor Stage, First Obstetric Labor Complications prevention & control Pain prevention & control Pregnancy Pregnancy Outcome Randomized Controlled Trials as Topic Time Factors 41 2005 1 25 9 0 2005 2 3 9 0 2005 1

2005 BJOG

189527. Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis. (PubMed)

Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis. In animals, excessive core body temperatures have been documented to cause malformations; neural tube defects (NTDs) are among the most frequently reported. In humans, data are inconclusive and often conflicting. The objective of our report is to determine the risk for neural tube defects associated with maternal hyperthermia in early pregnancy.We conducted a systematic review and meta (...) -analysis to evaluate available evidence on this topic in humans. MEDLINE, EMBASE, references from published reports, and biologic abstracts from meetings were searched for relevant studies. Reviewers evaluated all the retrieved articles and extracted the relevant data. Individual and summary odds ratios and relative risks were calculated using the Mantel-Haenszel method.Fifteen studies, reporting on 1,719 cases and 37,898 noncases, were included in the meta-analysis. The overall odds ratio for neural

2005 Epidemiology (Cambridge, Mass.)

189528. Reoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis. (PubMed)

Reoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis. 15710999 2005 03 15 2018 11 13 0017-5749 54 3 2005 Mar Gut Gut Reoperative chemoradiotherapy for oesophageal cancer: a systematic review and meta-analysis. 440-1 Demeester S R SR eng Comment Letter England Gut 2985108R 0017-5749 AIM IM Gut. 2004 Jul;53(7):925-30 15194636 Adenocarcinoma therapy Chemotherapy, Adjuvant Esophageal Neoplasms therapy Humans Meta-Analysis as Topic Radiotherapy, Adjuvant 2005 2

Full Text available with Trip Pro

2005 Gut

189529. Asymptomatic postoperative deep vein thrombosis and the development of postthrombotic syndrome. A systematic review and meta-analysis. (PubMed)

Asymptomatic postoperative deep vein thrombosis and the development of postthrombotic syndrome. A systematic review and meta-analysis. Perioperative antithrombotic clinical regimens have reduced the incidence of postoperative deep venous thrombosis (DVT). Long-term effects of asymptomatic postoperative DVT have been studied in a number of clinical trials and the present review describes the clinical significance of asymptomatic postoperative DVT regarding the possible development (...) of postthrombotic syndrome (PTS). We performed a systematic review of reference databases focusing upon studies including patients suspected of having postoperative DVT and reporting subsequent cases of PTS at the end of a well-defined follow-up period. The included studies were stratified according to type of screening method and applied statistics. Over-all evaluation included meta-analyses based upon the Cochrane software package. The overall relative risk of developing PTS was 1.58 (95% confidence intervals

2005 Thrombosis and haemostasis

189530. CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis. (PubMed)

CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis. Two common variant alleles of the cytochrome CYP2C9 (CYP2C9*2 and CYP2C9*3) lead to reduced warfarin metabolism in vitro and in vivo. The study objective was to examine the strength and quality of existing evidence about CYP2C9 gene variants and clinical outcomes in warfarin-treated patients.The study was a systematic review and meta-analysis. Multiple electronic

2005 Genetics in medicine : official journal of the American College of Medical Genetics

189531. Atrial flutter and the risk of thromboembolism: a systematic review and meta-analysis. (PubMed)

Atrial flutter and the risk of thromboembolism: a systematic review and meta-analysis. We conducted a systematic review and meta-analysis of observational studies to assess the risk of thromboembolism associated with atrial flutter.MEDLINE, EMBASE, bibliographies, and consultation with clinical experts were used to identify studies that report the risk of thromboembolism associated with attempted cardioversion and longer-term risk in chronic atrial flutter. The review process and data

2005 The American journal of medicine

189532. The accuracy of MRI in diagnosis of suspected deep vein thrombosis: systematic review and meta-analysis. (PubMed)

The accuracy of MRI in diagnosis of suspected deep vein thrombosis: systematic review and meta-analysis. Magnetic resonance imaging (MRI) may be used to diagnose deep vein thrombosis (DVT) in patients for whom ultrasound examination is inappropriate or unfeasible. We undertook a systematic review of the literature and meta-analysis to estimate the diagnostic accuracy of MRI for DVT. We searched databases of medical literature and citation lists of retrieved articles. We selected studies (...) that compared MRI with a reference standard in patients with suspected DVT or suspected pulmonary embolus, or high-risk asymptomatic patients. Data were analysed by random effects meta-analysis. We included 14 articles in the meta-analysis. Most compared MRI with venography in patients with clinically suspected DVT. The pooled estimate of sensitivity was 91.5% (95% CI: 87.5-94.5%) and the pooled estimate of specificity was 94.8% (95% CI: 92.6-96.5%). Sensitivity for proximal DVT was higher than sensitivity

2007 European radiology

189533. Spinal cord stimulation in complex regional pain syndrome and refractory neuropathic back and leg pain/failed back surgery syndrome: results of a systematic review and meta-analysis. (PubMed)

Spinal cord stimulation in complex regional pain syndrome and refractory neuropathic back and leg pain/failed back surgery syndrome: results of a systematic review and meta-analysis. The drive for good quality evidence has highlighted the importance of well-conducted systematic reviews and meta-analyses that critically evaluate and grade studies for new or existing therapies. A systematic review and meta-analysis was performed to review the efficacy, safety, and cost effectiveness of spinal

2006 Journal of pain and symptom management

189534. Coffee and gastric cancer: systematic review and meta-analysis. (PubMed)

Coffee and gastric cancer: systematic review and meta-analysis. We systematically reviewed the literature on the association between coffee consumption and gastric cancer and performed a meta-analysis of the results. Published cohort and case-control studies were identified in PubMed and reference lists. Random effects meta-analysis was used to pool effects from 23 studies, and heterogeneity was explored by stratification and meta-regression. The odds ratio (OR) for the overall association (...) ) for the two studies from South America. In this meta-analysis we found no adverse effect of coffee associated with gastric cancer. Knowledge on the level of exposure to different coffee constituents may provide a deeper understanding of this reassuring result and the real role of coffee on cancer risk.

2006 Cadernos de Saúde Pública / Ministério da Saúde

189535. A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases. (PubMed)

A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases. This systematic review attempted to summarize the associations between the Asn291Ser variant in the lipoprotein lipase (LPL) gene and dyslipidemia, the risk of type 2 diabetes mellitus (T2DM), and coronary heart disease (CHD). In addition, the relationships between the Asn291Ser variant and other metabolic diseases such as obesity and high blood pressure were also investigated (...) in this systematic review. We systematically reviewed the literature by means of a meta-analysis. Twenty-one articles, including 19,246 white subjects, were selected for this meta-analysis. The summary standardized mean difference (SMD) of plasma triglyceride (TG) for carriers compared with noncarriers of the Asn291Ser variant was 3.23 (P < 0.00001). The summary SMD of plasma HDL-cholsterol (HDL-C) for carriers compared with noncarriers of the Asn291Ser variant was -3.42 (P < 0.0001). The summary SMD

Full Text available with Trip Pro

2006 Journal of lipid research

189536. Prenatal exposure to misoprostol and congenital anomalies: systematic review and meta-analysis. (PubMed)

Prenatal exposure to misoprostol and congenital anomalies: systematic review and meta-analysis. The present systematic review was proposed with the objective of estimating the risk of congenital anomalies and other adverse events in children exposed to misoprostol during fetal life. The data source consisted of case-control studies that analyzed the effect of prenatal exposure to misoprostol on the pregnancy outcome, which were located in electronic databases and published up to June 2005 (...) . The outcomes of interest included congenital anomalies, fetal death, low birth weight and prematurity. The odds ratios (OR) for the individual studies were pooled by meta-analysis. Sensitivity tests and heterogeneity analysis were performed. Four studies involving 4899 cases of congenital anomalies and 5742 controls were included in accordance with the selection criteria. None of the studies analyzed other adverse effects from misoprostol on the outcome from gestation. Increased risks of congenital

2006 Reproductive toxicology (Elmsford, N.Y.)

189537. Male circumcision and risk of syphilis, chancroid, and genital herpes: a systematic review and meta-analysis. (PubMed)

Male circumcision and risk of syphilis, chancroid, and genital herpes: a systematic review and meta-analysis. Male circumcision is associated with reduced risk of HIV infection. This may be partly because of a protective effect of circumcision on other sexually transmitted infections (STI), especially those causing genital ulcers, but evidence for such protection is unclear. Our objective was to conduct a systematic review and meta-analyses of the associations between male circumcision (...) ).This first systematic review of male circumcision and ulcerative STI strongly indicates that circumcised men are at lower risk of chancroid and syphilis. There is less association with HSV-2. Potential male circumcision interventions to reduce HIV in high risk populations may provide additional benefit by protecting against other STI.

Full Text available with Trip Pro

2006 Sexually transmitted infections

189538. Letter by Rundek et al regarding article, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis". (PubMed)

Letter by Rundek et al regarding article, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis". 17724268 2007 09 14 2007 11 15 1524-4539 116 9 2007 Aug 28 Circulation Circulation Letter by Rundek et al regarding article, "Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis". e317; author reply e318 Rundek Tatjana T Brook Robert D RD Spence J David JD eng (...) Comment Letter United States Circulation 0147763 0009-7322 AIM IM Circulation. 2007 Jan 30;115(4):459-67 17242284 Cardiovascular Diseases epidemiology Carotid Arteries pathology Carotid Artery Diseases epidemiology Humans Meta-Analysis as Topic Stroke epidemiology Tunica Media pathology 2007 8 29 9 0 2007 9 15 9 0 2007 8 29 9 0 ppublish 17724268 116/9/e317 10.1161/CIRCULATIONAHA.107.696385

Full Text available with Trip Pro

2007 Circulation

189539. Quality of life assessed with the Medical Outcomes Study Short Form 36-Item Health Survey of patients on renal replacement therapy: a systematic review and meta-analysis. (PubMed)

Quality of life assessed with the Medical Outcomes Study Short Form 36-Item Health Survey of patients on renal replacement therapy: a systematic review and meta-analysis. The Medical Outcomes Study Short Form 36-Item Health Survey (SF-36) is the most widely used generic instrument to estimate quality of life of patients on renal replacement therapy. Purpose of this study was to summarize and compare the published literature on quality of life of hemodialysis (HD), peritoneal dialysis (PD

Full Text available with Trip Pro

2007 Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

189540. Letter to the editor concerning Petignat et al.'s "Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA testing? A systematic review and meta-analysis." Gynecol Oncol 2007;105(2): 530-535. (PubMed)

Letter to the editor concerning Petignat et al.'s "Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA testing? A systematic review and meta-analysis." Gynecol Oncol 2007;105(2): 530-535. 17904206 2008 01 07 2007 12 06 1095-6859 107 3 2007 Dec Gynecologic oncology Gynecol. Oncol. Letter to the editor concerning Petignat et al.'s "Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA (...) testing? A systematic review and meta-analysis." Gynecol Oncol 2007;105(2): 530-535. 595-6; author reply 596-7 Pretorius Robert G RG Belinson Jerome L JL eng Comment Letter 2007 09 27 United States Gynecol Oncol 0365304 0090-8258 0 DNA, Viral IM Gynecol Oncol. 2007 May;105(2):530-5 17335880 Cervix Uteri pathology virology DNA, Viral analysis Female Humans Papillomaviridae genetics isolation & purification Papillomavirus Infections pathology virology Self-Examination Specimen Handling methods Vaginal

2007 Gynecologic oncology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>