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1. Oral progesterone for the prevention of recurrent preterm birth: systematic review and metaanalysis. (Abstract)

Oral progesterone for the prevention of recurrent preterm birth: systematic review and metaanalysis. The purpose of this study was to perform a systematic review and metaanalysis of randomized controlled trials on oral progesterone compared with placebo or other interventions for preterm birth prevention in singleton pregnancies with previous spontaneous preterm birth. The primary outcome was preterm birth at <37 weeks gestation; the secondary outcomes included preterm birth rate at <34 weeks (...) gestation, neonatal morbidity/death, and maternal side-effects.Searches were performed in PubMed, Scopus, ClinicalTrials.gov, PROSPERO, EMBASE, and the Cochrane Register with the use of a combination of words related to "preterm birth," "preterm delivery," "progesterone," "progestogens," and "oral" from inception of each database to April 2018. Additionally, systematic reviews on progesterone for preterm birth prevention that were identified in our search were also reviewed for additional studies. We

2019 American journal of obstetrics & gynecology MFM Controlled trial quality: predicted high

2. Levonorgestrel intrauterine system associated amenorrhea: a systematic review and metaanalysis Full Text available with Trip Pro

Levonorgestrel intrauterine system associated amenorrhea: a systematic review and metaanalysis Amenorrhea is a polarizing noncontraceptive effect of the levonorgestrel intrauterine system. Composite amenorrhea prevalence estimates that summarize all clinical data for the first-year after insertion currently are not available. The purpose of this study was to investigate the validity of existing prevalence estimates by the systematic calculation of amenorrhea measures for a general population (...) were resolved by a third reviewer. Where possible, data were pooled with the use of a random-effects model.Of 2938 potentially relevant studies, we included 9 in our meta-analysis. We calculated amenorrhea prevalence, which was weighted for inter- and intrastudy variance, for 4 90-day intervals and months 0-12. Our results demonstrated few levonorgestrel intrauterine system users (0.2%; 95% confidence interval, 0.0-0.4) experienced amenorrhea during the first 90 days after insertion; however

2019 EvidenceUpdates

3. Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis (Abstract)

Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis Several cell-based therapies have been proposed in recent years the management of low back pain, including the injection of medicinal signaling cells or mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP). However, there is only emerging clinical evidence to support their use at this time.To assess the effectiveness of MSCs or PRP injections in the treatment of low (...) back and lower extremity pain.A systematic review and metaanalysis of the effectiveness of PRP and MSCs injections in managing low back and lower extremity pain.PubMed, Cochrane Library, US National Guideline Clearinghouse, prior systematic reviews, and reference lists. The literature search was performed from 1966 through June 2018.Randomized trials, observational studies, and case reports of injections of biologics into the disc, epidural space, facet joints, or sacroiliac joints.Data extraction

2019 EvidenceUpdates

4. Do evidence summaries increase health policy?makers' use of evidence from systematic reviews? A systematic review Full Text available with Trip Pro

studies. Assessment of heterogeneity Our included studies assessed interventions and reported outcomes that were too different to pool; therefore, metaanalysis was not possible. If it had been, we planned to explore heterogeneity using forest plots and the I 2 statistic according to guidance of the Cochrane Handbook for Systematic Reviews of Interventions (Higgins et al.). We were also thus unable to conduct planned meta‐regression to assess the role of mediating factors, such as: target audience (...) as high risk of bias or studies in which there were unit of analysis errors that could not be reanalysed but metaanalysis was not possible. Results Description of studies Results of the search The search strategy yielded 11,733 references (10,113 after removal of duplicates). depicts the results of the search and screening. During the title and abstract screening process we excluded 10,059 references for failing to meet one or more of our inclusion criteria. The remaining 50 references were reviewed

2018 Campbell Collaboration

5. Noninvasive Ventilation and Survival in Acute Care Settings: A Comprehensive Systematic Review and Metaanalysis of Randomized Controlled Trials

Noninvasive Ventilation and Survival in Acute Care Settings: A Comprehensive Systematic Review and Metaanalysis of Randomized Controlled Trials PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2015 PedsCCM Evidence-Based Journal Club

6. Progestogens in singleton gestations with preterm prelabor rupture of membranes: a systematic review and metaanalysis of randomized controlled trials (Abstract)

Progestogens in singleton gestations with preterm prelabor rupture of membranes: a systematic review and metaanalysis of randomized controlled trials Preterm prelabor rupture of membranes occurs in 3% of all pregnancies. Neonatal benefit is seen in uninfected women who do not deliver immediately after preterm prelabor rupture of membranes. The purpose of this study was to evaluate whether the administration of progestogens in singleton pregnancies prolongs pregnancy after preterm prelabor (...) to delivery. Metaanalysis was performed with the use of the random effects model of DerSimonian and Laird to produce relative risk with 95% confidence interval. Analysis was performed for each mode of progestogen administration separately.Six randomized controlled trials (n=545 participants) were included. Four of the included trials assessed the efficacy of 17-α hydroxyprogesterone caproate; 1 trial assessed rectal progestogen, and 1 trial had 3 arms that compared 17-α hydroxyprogesterone caproate

2018 EvidenceUpdates

7. FSRH CEU Statement to published systematic review: The relationship between progestin hormonal contraception and depression: a systematic review

evidence relating to risk of depression associated with use of progestogen-only contraception (POC).1 The authors of the review conclude that the bulk of the evidence does not support an association between use of POC and depression based on validated measures. Meta-analysis was not possible due to the heterogeneity of studies. Your download should start automatically. If not . Document types Thinking about taking a qualification? Registration is now quick and easy online. About FSRH FSRH is a faculty (...) FSRH CEU Statement to published systematic review: The relationship between progestin hormonal contraception and depression: a systematic review FSRH CEU Statement to published systematic review: The relationship between progestin hormonal contraception and depression: a systematic review - Faculty of Sexual and Reproductive Healthcare FSRH CEU Statement to published systematic review: The relationship between progestin hormonal contraception and depression: a systematic review FSRH CEU

2018 Faculty of Sexual & Reproductive Healthcare

8. Pars plana vitrectomy for vitreomacular traction syndrome: a systematic review and metaanalysis of safety and efficacy

Pars plana vitrectomy for vitreomacular traction syndrome: a systematic review and metaanalysis of safety and efficacy Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2014 DARE.

9. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and meta-analysis

Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and meta-analysis Redirecting

2020 Covid-19 Ad hoc papers

10. COVID-19 Computed Tomography Findings: A Systematic Review and Meta-Analysis

COVID-19 Computed Tomography Findings: A Systematic Review and Meta-Analysis Redirecting

2020 Covid-19 Ad hoc papers

11. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis

Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Redirecting

2020 Covid-19 Ad hoc papers

12. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis

Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis Redirecting

2020 Covid-19 Ad hoc papers

13. Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and meta-analysis Full Text available with Trip Pro

Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and meta-analysis Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and metaanalysis - Long - - Journal of Evidence-Based Medicine - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term ARTICLE Free Access Effectiveness of N95 respirators versus surgical masks (...) against influenza: A systematic review and metaanalysis Chinese Evidence‐Based Medicine Center, West China Hospital, Sichuan University, Chengdu, P.R. China West China School of Medicine, Sichuan University, Chengdu, P.R. China West China School of Medicine, Sichuan University, Chengdu, P.R. China School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China Chinese Evidence‐Based Medicine Center, West China Hospital, Sichuan University, Chengdu, P.R. China

2020 Covid-19 Ad hoc papers

14. Covid-19: Physical interventions to interrupt or reduce the spread of respiratory viruses. Part 1 - Face masks, eye protection and person distancing: systematic review and meta-analysis

Covid-19: Physical interventions to interrupt or reduce the spread of respiratory viruses. Part 1 - Face masks, eye protection and person distancing: systematic review and meta-analysis Physical interventions to interrupt or reduce the spread of respiratory viruses. Part 1 - Face masks, eye protection and person distancing: systematic review and meta-analysis | medRxiv Search for this keyword Physical interventions to interrupt or reduce the spread of respiratory viruses. Part 1 - Face masks (...) , eye protection and person distancing: systematic review and meta-analysis Tom Jefferson , Mark Jones , Lubna A Al Ansari , Ghada Bawazeer , Elaine Beller , Justin Clark , John Conly , Chris Del Mar , Elisabeth Dooley , Eliana Ferroni , Paul Glasziou , Tammy Hoffman , Sarah Thorning , Mieke Van Driel doi: https://doi.org/10.1101/2020.03.30.20047217 Tom Jefferson 1 University of Oxford; For correspondence: Mark Jones 2 Bond University, Australia; For correspondence: Lubna A Al Ansari 3 Kind Saud

2020 Covid-19 Ad hoc papers

15. Airway clearance techniques for cystic fibrosis: an overview of Cochrane systematic reviews. Full Text available with Trip Pro

Airway clearance techniques for cystic fibrosis: an overview of Cochrane systematic reviews. Cystic fibrosis is a life-limiting genetic condition in which thick mucus builds up in the lungs, leading to infections, inflammation, and eventually, deterioration in lung function. To clear their lungs of mucus, people with cystic fibrosis perform airway clearance techniques daily. There are various airway clearance techniques, which differ in terms of the need for assistance or equipment, and cost.To (...) summarise the evidence from Cochrane Reviews on the effectiveness and safety of various airway clearance techniques in people with cystic fibrosis.For this overview, we included Cochrane Reviews of randomised or quasi-randomised controlled trials (including cross-over trials) that evaluated an airway clearance technique (conventional chest physiotherapy, positive expiratory pressure (PEP) therapy, high-pressure PEP therapy, active cycle of breathing techniques, autogenic drainage, airway oscillating

2019 Cochrane

16. Early amniotomy after cervical ripening for induction of labor: a systematic review and metaanalysis of randomized controlled trials. (Abstract)

Early amniotomy after cervical ripening for induction of labor: a systematic review and metaanalysis of randomized controlled trials. Timing of artificial rupture of membranes (ie, amniotomy) in induction of labor is controversial, because it has been associated not only with shorter labors, but also with fetal nonreassuring testing, at times necessitating cesarean delivery. The aim of this systematic review and metaanalysis of randomized trials was to evaluate the effectiveness of early (...) amniotomy vs late amniotomy or spontaneous rupture of membranes after cervical ripening.The search was conducted with the use of electronic databases from inception of each database through February 2019. Review of articles included the abstracts of all references that were retrieved from the search.Selection criteria included randomized clinical trials that compared early amniotomy vs control (ie, late amniotomy or spontaneous rupture of membranes) after cervical ripening with either Foley catheter

2019 American Journal of Obstetrics and Gynecology

17. Venous Thrombotic Risk in Transgender Women Undergoing Estrogen Therapy: A Systematic Review and Metaanalysis. Full Text available with Trip Pro

Venous Thrombotic Risk in Transgender Women Undergoing Estrogen Therapy: A Systematic Review and Metaanalysis. Transgender women are female individuals who were recorded men at birth based on natal sex. Supporting a person's gender identity improves their psychological health, and gender-affirming hormones reduce gender dysphoria and benefit mental health. For transgender women, estrogen administration has clinically significant benefits. Previous reviews have reported conflicting literature (...) on the thrombotic risk of estrogen therapy in transgender women and have highlighted the need for more high-quality research.To help address the gap in understanding thrombotic risk in transgender women receiving estrogen therapy, we performed a systematic literature review and metaanalysis. Two evaluators independently assessed quality using the Ottawa Scale for Cohort Studies. The Poisson normal model was used to estimate the study-specific incidence rates and the pooled incidence rate. Heterogeneity

2019 Clinical Chemistry

18. Prevalence and main outcomes of placenta accreta spectrum: a systematic review and metaanalysis. (Abstract)

Prevalence and main outcomes of placenta accreta spectrum: a systematic review and metaanalysis. The objective of this study was to evaluate the prevalence of placenta accreta spectrum in general population studies and the main maternal outcomes at delivery.Data sources: We searched PubMed, Google Scholar, clinicalTrials.gov and MEDLINE between 1982 and 2018.Articles providing data on the number of cases of placenta accreta spectrum per pregnancies, births or deliveries in a defined (...) of the diagnosis and differential diagnosis between adherent and invasive accreta placentation.This meta-analysis indicates wide variation between studies for the prevalence rate of placenta accreta spectrum and for the different grades of accreta placentation, highlighting the need for consistency in definitions used to describe placenta accreta spectrum at birth and in reporting on this increasing common obstetric complication.Copyright © 2019. Published by Elsevier Inc.

2019 American Journal of Obstetrics and Gynecology

19. Pregnancy outcomes in women with kidney transplant: Metaanalysis and systematic review. Full Text available with Trip Pro

Pregnancy outcomes in women with kidney transplant: Metaanalysis and systematic review. Reproductive function in women with end stage renal disease generally improves after kidney transplant. However, pregnancy remains challenging due to the risk of adverse clinical outcomes.We searched PubMed/MEDLINE, Elsevier EMBASE, Scopus, BIOSIS Previews, ISI Science Citation Index Expanded, and the Cochrane Central Register of Controlled Trials from date of inception through August 2017 for studies

2019 BMC Nephrology

20. Interventions for Temporomandibular Joint Disorder: An Overview of Systematic Reviews

Interventions for Temporomandibular Joint Disorder: An Overview of Systematic Reviews Interventions for Temporomandibular Joint Disorder: An Overview of Systematic Reviews | CADTH.ca Find the information you need Interventions for Temporomandibular Joint Disorder: An Overview of Systematic Reviews Interventions for Temporomandibular Joint Disorder: An Overview of Systematic Reviews Last updated: May 9, 2019 Project Number: RE0035-000 Product Line: Result type: Report Temporomandibular disorders (...) (TMD) are disorders involving the temporomandibular joint (TMJ) and associated structures, and affect approximately 5% to 12% of individuals. TMD can lead to chronic pain, tooth grinding, and cervical spine and mobility issues, all of which are precursors to more serious impairment of function. There are a plethora of different strategies to treat TMD, including pharmacological interventions, non-surgical interventions, and surgery. An overview and critical appraisal of systematic reviews relevant

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

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