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18221. Vaccine independence, local competences and globalisation: lessons from the history of pertussis vaccines. (PubMed)

Vaccine independence, local competences and globalisation: lessons from the history of pertussis vaccines. In the context of global vaccine politics 'vaccine independence' has been defined as the assumption of financial responsibility for vaccine procurement. This paper suggests 'the possibility of vaccine choice' as an alternative meaning for the term. How far does local competence in vaccine development and production provide that possibility? Coupled to the national vaccination programme (...) (or whooping cough) vaccines, where again controversy surrounds the relative merits of alternative vaccines, permits the question to be posed anew. Results of our analysis from the Netherlands suggest, first, that the pressure to conform has become greater, and second, that the taken-for-granted globalism of today's vaccine system is in need of critical examination.

2006 Social Science & Medicine

18222. Medical student-run health clinics: important contributors to patient care and medical education. (Full text)

Medical student-run health clinics: important contributors to patient care and medical education. Despite the popularity of medical student-run health clinics among U.S. medical schools, there is no information about how many clinics exist, how many students volunteer there, or how many patients they see and what services they offer.We describe, for the first time, the prevalence and operation of medical student-run health clinics nationwide.A web-based survey was sent to all 124 Association (...) ; 31% Black/African American; 25% White; 11% Asian; and 3% Native American or other. Most student-run health clinics had resources both to treat acute illness and also to manage chronic conditions. Clinics were most often funded by private grants (42/59, 71%); among 27 clinics disclosing finances, a median annual operating budget of $12,000 was reported.Medical student-run health clinics offer myriad services to disadvantaged patients and are also a notable phenomenon in medical education. Wider

2007 Journal of General Internal Medicine

18223. A meeting of minds: interdisciplinary research in the health sciences in Canada. (Full text)

of researchers does not always bear this out. This article examines government, industry and academia to identify the cultural and structural characteristics that demand, promote or prevent IDHR in each sector. At its heart is the question, How can universities best support and enhance IDHR, not only for the benefit of science, but also to meet the growing needs of industry and government for intellectual capital? Focusing on the predominant health sciences disciplines, the authors define IDHR as a team (...) and government sectors is not intended to offer rigorous data on the current state of IDHR in Canada. Rather, the goal is to stimulate research-policy dialogue by suggesting a number of immediate measures that can help promote IDHR in Canada. Recommended measures to support IDHR are aimed at better resourcing and recognition (by universities and granting agencies), along with novel approaches to training, such as government-and industry-based studentships. In addition, we recommend that professional

2006 Canadian Medical Association Journal

18224. Sustainability of public health programs: the example of tobacco treatment services in Massachusetts. (Full text)

Sustainability of public health programs: the example of tobacco treatment services in Massachusetts. Sustaining important public or grant-funded services after initial funding is terminated is a major public health challenge. We investigated whether tobacco treatment services previously funded within a statewide tobacco control initiative could be sustained after state funding was terminated abruptly. We found that 2 key strategies-redefining the scope of services being offered and creative

2006 American Journal of Public Health

18225. An open democracy (Full text)

information (e.g., intelligence, internal reports, etc) that are required for self-evaluation and defense against threats to the nation. Governments are granted a privilege to collect, store and use such information to perform necessary tasks. How far does governmental privilege go relative to the intrinsic right of citizens to access and evaluate information?

2007 Molecular Cancer

18226. Apoplastic pH During Low-oxygen Stress in Barley (Full text)

Apoplastic pH During Low-oxygen Stress in Barley Anoxia leads to an energy crisis, tolerance of which varies from plant to plant. Although the apoplast represents an important storage and reaction space, and engages in the mediation of membrane transport, this extracellular compartment has not yet been granted a role during oxygen shortage. Here, an attempt is made to highlight the importance of the apoplast during oxygen stress and to test whether information about it is transferred (...) mediation of energy-rich compounds is evident. It is concluded that anoxia tolerance depends on how the plant is able to hold the proton motive force and H(+) turnover at a level that guarantees sufficient energy is harvested to overcome the crisis.

2006 Annals of botany

18227. Parent perceptions of school-based support for students with traumatic brain injuries (Full text)

following school re-entry. They then rated how difficult it was to obtain support or services from the school and how satisfied they were with the support or services.The majority of participants did not perceive the need for school-based services, even when the injury was severe. Almost all students whose parents perceived a need for an adjusted schedule were granted that accommodation, but few students received school-based counselling or behavioural support.Results indicated that participants

2008 Brain Injury

18228. COURAGE: PCI vs. medical therapy in stable CAD

COURAGE: PCI vs. medical therapy in stable CAD COURAGE - Wiki Journal Club COURAGE From Wiki Journal Club Jump to: , Boden WE, et al. "Optimal medical therapy with or without PCI for stable coronary disease". The New England Journal of Medicine . 2007. 356:1503-16. • • Contents Clinical Question In patients with stable CAD, how does optimal medical therapy plus PCI compare to optimal medical therapy alone in improving survival? Bottom Line In patients with stable CAD, there were no differences (...) undergoing PCI do so electively, this is probably closer to 30% with many of those likely meeting COURAGE exclusion criteria High rate of excluded patients Inclusion of angioplasty likely worsened outcomes Likely incomplete revascularization given discordance between the incidence of multivessel disease and procedures with multiple stents placed No stratification by ischemic burden Unclear how long patients took clopidogrel or if extended duration of therapy would improve outcomes in the PCI group

2007 Wiki Journal Club

18229. Emergence of relations and the essence of learning: a review of Sidman's Equivalence relations and behavior: a research story. Book review. (Full text)

and how it relates to behavior. Sidman used the idea of stimulus-stimulus relations among features of the environment to develop his theories about equivalence relations. Experimental work with children and animals demonstrated their ability to use equivalence relations to learn new tasks. The subject received feedback and reinforcement for specific choices made during training, then was presented with new choices during testing. Results of the tests indicate that subjects were able to establish (...) relations and retrieve them in different situations. NASA Discipline Number 06-10 NASA Discipline Space Human Factors NASA Program Space Human Factors Non-NASA Center Rumbaugh D M DM GA St U, Atlanta Grant numbers: NAG2-438 1995 10 1 0 0 2001 9 11 10 1 1995 10 1 0 0 ppublish 11539166 PMC2733722 Brain. 1965 Jun;88(2):237-94 5318481 Brain. 1965 Sep;88(3):585-644 5318824 Psychol Sci. 1991 May;2(3):190-3 11537106

1995 The Behavior Analyst

18230. Statistical inference in behavior analysis: Useful friend (Full text)

is valued. Knowing how to use statistical inferential procedures would make behavior analysts more methodologically sophisticated. It would also help them to critically evaluate research in other areas of psychology, obtain research grants, and publish their research in diverse outlets, which would help others to see behavior-analytic work.

1999 The Behavior Analyst

18231. Gefitinib in Treating Patients With Cervical Cancer

: RATIONALE: Biological therapies such as gefitinib may interfere with the growth of the tumor cells and slow the growth of cervical cancer. Comparing results of diagnostic procedures performed before, during, and after treatment with gefitinib may help doctors predict a patient's response to treatment and help plan the most effective treatment. PURPOSE: This phase II trial is studying how well gefitinib works in treating patients with cervical cancer. Condition or disease Intervention/treatment Phase (...) and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00049556 Locations Layout table for location information United States, Maryland Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support Bethesda, Maryland, United States, 20892-1182 NCI - Center

2002 Clinical Trials

18232. Olanzapine Versus Placebo in the Treatment of Mania in Adolescents With Bipolar I Disorder

and Company Information provided by: Eli Lilly and Company Study Details Study Description Go to Brief Summary: The purpose of this study is to determine the efficacy (how well the drug works), safety, and any side effects of olanzapine compared to placebo in the treatment of mania in bipolar disorder in adolescents. Both the potential benefits and side effects of olanzapine will be evaluated throughout this trial. Condition or disease Intervention/treatment Phase Bipolar Disorder Drug: Olanzapine Drug (...) a document granting consent. Female patients of child-bearing potential must test negative for pregnancy at the time of enrollment based on a serum pregnancy test. Exclusion Criteria: Female patients who are either pregnant or nursing. Current diagnosis of schizophrenia, schizophreniform disorder, or schizoaffective disorder. Patient with acute or unstable medical conditions, such that intensive care unit hospitalization for the disease is anticipated within 6 months. Patients who have previously

2002 Clinical Trials

18233. Enhanced Linkage Maps From Family-Based Genetics Studies

. Accurate estimates of meiotic map distance cannot be obtained by any means other than by linkage analysis using genotype data. The study is in response to a Request for Applications entitled "NHLBI Innovative Research Grant Program" released in July, 2001. The purpose of the initiative is to support new approaches to heart, lung, and blood diseases and sleep disorders that use existing data sets or existing biological specimen collections whether obtained through National Heart, Lung, and Blood (...) Institute support or not. DESIGN NARRATIVE: The genetic epidemiology study will build improved highly-precise sex-specific linkage maps utilizing thousands of individuals who have previously been genotyped. After filtering out obvious relationship and genotype errors, the study will incorporate methods that properly model for genotyping errors. In addition to creating precise maps for the scientific community, the study will also use these genotype data to study how recombination may vary between ethnic

2002 Clinical Trials

18234. Ixabepilone in Treating Patients With Locally Advanced or Metastatic Breast Cancer

) Information provided by: National Cancer Institute (NCI) Study Details Study Description Go to Brief Summary: RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: This phase II trial is studying how well ixabepilone works in treating patients with locally advanced or metastatic breast cancer. Condition or disease Intervention/treatment Phase Breast Cancer Drug: ixabepilone Phase 2 Detailed Description: OBJECTIVES: Determine (...) the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00045097 Locations Layout table for location information United States, Maryland Suburban Hospital Bethesda, Maryland, United States, 20814 Oncology Care Associates Bethesda, Maryland, United States, 20817 Warren Grant Magnuson Clinical Center - NCI

2002 Clinical Trials

18235. SU5416 in Treating Patients With Refractory or Relapsed Multiple Myeloma

, United States, 37232-6838 Sponsors and Collaborators Fox Chase Cancer Center National Cancer Institute (NCI) Investigators Layout table for investigator information Study Chair: Mitchell R. Smith, MD, PhD Fox Chase Cancer Center More Information Go to Layout table for additonal information Responsible Party: Fox Chase Cancer Center ClinicalTrials.gov Identifier: Other Study ID Numbers: FCCC-00009 CDR0000068022 ( Registry Identifier: PDQ (Physician Data Query) ) NCI-58 ( Other Grant/Funding Number

2000 Clinical Trials

18236. R115777 in Treating Patients With Progressive, Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

Fox Chase Cancer Center More Information Go to Layout table for additonal information Responsible Party: Fox Chase Cancer Center ClinicalTrials.gov Identifier: Other Study ID Numbers: FCCC-99031 CDR0000067866 ( Registry Identifier: PDQ (Physician Data Query) ) NCI-20 ( Other Grant/Funding Number: National Cancer Institute ) First Posted: March 16, 2004 Last Update Posted: July 11, 2013 Last Verified: July 2013 Keywords provided by Fox Chase Cancer Center: adenocarcinoma of the prostate stage IV

2000 Clinical Trials

18237. Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma

Query) ) NCI-T95-0075H ( Other Grant/Funding Number: National Cancer Institute ) First Posted: May 3, 2004 Last Update Posted: July 11, 2013 Last Verified: July 2013 Keywords provided by Fox Chase Cancer Center: stage III adult Hodgkin lymphoma stage IV adult Hodgkin lymphoma recurrent adult Hodgkin lymphoma stage III cutaneous T-cell non-Hodgkin lymphoma stage IV cutaneous T-cell non-Hodgkin lymphoma recurrent cutaneous T-cell non-Hodgkin lymphoma small intestine lymphoma unspecified adult solid

2000 Clinical Trials

18238. Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps

to this study by ClinicalTrials.gov Identifier (NCT Number): Layout table for additonal information Responsible Party: National Cancer Institute (NCI) ClinicalTrials.gov Identifier: Other Study ID Numbers: NCI-2012-02327 98-008 NYH-CMC-0298-108 SC-IQ4-99-02-005 CDR0000067750 NCI-P00-0141 STRANG-98-008 BWH-NO1-CN-95015 N01CN95015 ( Other Grant/Funding Number: US NIH Grant/Contract Award Number ) First Posted: November 5, 2003 Last Update Posted: April 12, 2013 Last Verified: April 2013 Additional relevant (...) in FAP patients. The use of celecoxib may be an effective way to prevent the development of sporadic adenomatous polyps, precursors of colorectal cancer. This randomized phase III trial is studying celecoxib to see how well it works compared to a placebo in preventing the development of adenomatous colorectal polyps in patients who have had at least one polyp removed. Condition or disease Intervention/treatment Phase Colon Cancer Rectal Cancer Drug: celecoxib Other: placebo Phase 3 Detailed

2000 Clinical Trials

18239. Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer

University Medical Center Stanford, California, United States, 94305-5408 Sponsors and Collaborators Stanford University National Cancer Institute (NCI) Investigators Layout table for investigator information Study Chair: Harlan A. Pinto, MD Stanford University More Information Go to Publications of Results: Layout table for additonal information Responsible Party: Stanford University ClinicalTrials.gov Identifier: Other Study ID Numbers: IRB-12503 CA67166 ( Other Grant/Funding Number: Public Health

2000 Clinical Trials

18240. Cryosurgery in Treating Patients With Liver Cancer or Liver Metastases

Study ID Numbers: 93-0092.cc NCI-V95-0657 ( Other Grant/Funding Number: National Cancer Institute ) First Posted: August 11, 2004 Last Update Posted: July 22, 2013 Last Verified: July 2013 Keywords provided by University of Colorado, Denver: localized unresectable adult primary liver cancer recurrent adult primary liver cancer liver metastases Additional relevant MeSH terms: Layout table for MeSH terms Liver Neoplasms Neoplasm Metastasis Digestive System Neoplasms Neoplasms by Site Neoplasms

1999 Clinical Trials

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